Rattus norvegicus

114 known processes

S100a1

S100 calcium binding protein A1

S100a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.276
Rat
homeostatic process GO:0042592 331 0.177
inorganic cation transmembrane transport GO:0098662 202 0.158
oxoacid metabolic process GO:0043436 290 0.146
inorganic ion transmembrane transport GO:0098660 229 0.136
organic acid metabolic process GO:0006082 292 0.133
chemical homeostasis GO:0048878 292 0.108
carboxylic acid metabolic process GO:0019752 289 0.108
cellular chemical homeostasis GO:0055082 247 0.101
transmembrane transport GO:0055085 412 0.101
calcium ion homeostasis GO:0055074 162 0.094
cation transmembrane transport GO:0098655 263 0.093
response to transition metal nanoparticle GO:1990267 122 0.091
Rat
sodium ion transport GO:0006814 82 0.086
single organism behavior GO:0044708 130 0.086
cation transport GO:0006812 382 0.081
regulation of cellular component organization GO:0051128 368 0.080
Rat
sodium ion transmembrane transport GO:0035725 67 0.074
response to estrogen GO:0043627 232 0.073
ion homeostasis GO:0050801 212 0.072
response to ethanol GO:0045471 162 0.070
Rat
response to metal ion GO:0010038 253 0.067
Rat
cation homeostasis GO:0055080 195 0.066
cellular metal ion homeostasis GO:0006875 172 0.066
cellular divalent inorganic cation homeostasis GO:0072503 162 0.062
divalent inorganic cation homeostasis GO:0072507 165 0.062
cellular amino acid metabolic process GO:0006520 107 0.062
organophosphate metabolic process GO:0019637 370 0.056
glutathione metabolic process GO:0006749 15 0.055
metal ion transport GO:0030001 289 0.054
apoptotic process GO:0006915 381 0.054
Rat
cellular cation homeostasis GO:0030003 180 0.053
catabolic process GO:0009056 351 0.053
response to acid chemical GO:0001101 222 0.052
cellular calcium ion homeostasis GO:0006874 160 0.052
monovalent inorganic cation transport GO:0015672 172 0.052
ion transmembrane transport GO:0034220 365 0.049
regulation of nervous system development GO:0051960 264 0.048
regulation of multicellular organismal development GO:2000026 376 0.048
Rat
cellular response to stress GO:0033554 269 0.044
Rat
cellular lipid metabolic process GO:0044255 208 0.044
single organism catabolic process GO:0044712 283 0.044
response to monosaccharide GO:0034284 159 0.042
aging GO:0007568 241 0.042
response to alkaloid GO:0043279 132 0.042
metal ion homeostasis GO:0055065 186 0.041
cellular homeostasis GO:0019725 252 0.040
cellular response to endogenous stimulus GO:0071495 377 0.039
negative regulation of metabolic process GO:0009892 331 0.039
response to toxic substance GO:0009636 133 0.039
regulation of ion transport GO:0043269 245 0.038
programmed cell death GO:0012501 392 0.038
Rat
anatomical structure morphogenesis GO:0009653 298 0.038
Rat
behavior GO:0007610 205 0.037
cellular catabolic process GO:0044248 295 0.037
response to amino acid GO:0043200 75 0.035
amine metabolic process GO:0009308 38 0.034
response to genistein GO:0033595 4 0.033
response to estradiol GO:0032355 164 0.032
negative regulation of cell death GO:0060548 229 0.032
potassium ion transport GO:0006813 97 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
multicellular organismal signaling GO:0035637 44 0.030
intracellular signal transduction GO:0035556 314 0.030
response to extracellular stimulus GO:0009991 380 0.030
response to wounding GO:0009611 254 0.029
Rat
response to molecule of bacterial origin GO:0002237 194 0.029
Rat
cellular response to organonitrogen compound GO:0071417 197 0.029
regulation of molecular function GO:0065009 398 0.029
regulation of neuron differentiation GO:0045664 208 0.029
cellular amine metabolic process GO:0044106 38 0.029
transmission of nerve impulse GO:0019226 42 0.029
response to purine containing compound GO:0014074 126 0.029
regulation of cell differentiation GO:0045595 320 0.029
Rat
single organism biosynthetic process GO:0044711 342 0.028
response to nutrient levels GO:0031667 370 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
neurological system process GO:0050877 219 0.027
regulation of cell proliferation GO:0042127 359 0.027
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.027
brain development GO:0007420 247 0.026
Human
positive regulation of multicellular organismal process GO:0051240 387 0.026
secretion GO:0046903 307 0.026
response to carbohydrate GO:0009743 183 0.026
regulation of apoptotic process GO:0042981 335 0.026
Rat
positive regulation of biosynthetic process GO:0009891 319 0.026
xenobiotic metabolic process GO:0006805 19 0.025
response to oxidative stress GO:0006979 186 0.025
reproductive process GO:0022414 372 0.025
regulation of neurogenesis GO:0050767 247 0.025
single organism carbohydrate catabolic process GO:0044724 40 0.025
organic substance catabolic process GO:1901575 316 0.024
regulation of phosphorylation GO:0042325 248 0.024
central nervous system development GO:0007417 311 0.023
Human Rat
positive regulation of cell proliferation GO:0008284 249 0.023
Rat
regulation of signal transduction GO:0009966 318 0.023
carbohydrate metabolic process GO:0005975 130 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
response to decreased oxygen levels GO:0036293 237 0.023
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
Rat
regulation of rna metabolic process GO:0051252 391 0.022
response to xenobiotic stimulus GO:0009410 23 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
carbohydrate catabolic process GO:0016052 40 0.022
cellular ion homeostasis GO:0006873 184 0.022
potassium ion transmembrane transport GO:0071805 71 0.022
cellular potassium ion transport GO:0071804 72 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
regulation of programmed cell death GO:0043067 341 0.021
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.021
cellular amide metabolic process GO:0043603 44 0.021
cell projection organization GO:0030030 302 0.021
cytosolic calcium ion homeostasis GO:0051480 140 0.021
regulation of secretion GO:0051046 224 0.020
generation of precursor metabolites and energy GO:0006091 62 0.020
response to oxygen levels GO:0070482 265 0.020
Rat
response to zinc ion GO:0010043 39 0.020
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
positive regulation of cell communication GO:0010647 271 0.020
Rat
calcium ion transmembrane transport GO:0070588 70 0.020
positive regulation of nervous system development GO:0051962 178 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
positive regulation of response to stimulus GO:0048584 285 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
Rat
positive regulation of neurogenesis GO:0050769 165 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
response to lipopolysaccharide GO:0032496 191 0.019
Rat
response to bacterium GO:0009617 200 0.018
Rat
negative regulation of nervous system development GO:0051961 79 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
response to peptide GO:1901652 292 0.018
regulation of cell development GO:0060284 263 0.018
response to external biotic stimulus GO:0043207 221 0.018
Rat
negative regulation of programmed cell death GO:0043069 183 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
gland development GO:0048732 155 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
sexual reproduction GO:0019953 148 0.017
response to nitrosative stress GO:0051409 2 0.017
response to insulin GO:0032868 133 0.017
reproduction GO:0000003 245 0.017
response to organophosphorus GO:0046683 102 0.017
divalent metal ion transport GO:0070838 132 0.017
purine containing compound metabolic process GO:0072521 253 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
negative regulation of developmental process GO:0051093 125 0.016
Rat
multicellular organism reproduction GO:0032504 233 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
protein homooligomerization GO:0051260 91 0.016
positive regulation of cell death GO:0010942 184 0.016
Rat
lipid metabolic process GO:0006629 283 0.016
response to nutrient GO:0007584 248 0.016
muscle system process GO:0003012 115 0.016
regulation of secretion by cell GO:1903530 208 0.016
neuronal action potential GO:0019228 35 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
development of primary sexual characteristics GO:0045137 107 0.016
neuron differentiation GO:0030182 368 0.016
macromolecular complex assembly GO:0065003 273 0.015
cofactor metabolic process GO:0051186 95 0.015
single organism reproductive process GO:0044702 297 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
sulfur compound metabolic process GO:0006790 70 0.015
positive regulation of gene expression GO:0010628 244 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
Rat
regulation of metal ion transport GO:0010959 118 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
neuron projection development GO:0031175 273 0.015
response to ketone GO:1901654 182 0.015
regulation of catalytic activity GO:0050790 304 0.015
cellular component assembly GO:0022607 360 0.015
regulation of cell growth GO:0001558 85 0.015
response to cytokine GO:0034097 215 0.014
cell migration GO:0016477 197 0.014
response to heat GO:0009408 60 0.014
divalent inorganic cation transport GO:0072511 134 0.014
peptide metabolic process GO:0006518 32 0.014
intracellular transport GO:0046907 185 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
response to axon injury GO:0048678 59 0.014
secretion by cell GO:0032940 248 0.014
cell motility GO:0048870 202 0.014
negative regulation of skeletal muscle tissue development GO:0048642 3 0.014
Rat
dna metabolic process GO:0006259 96 0.014
response to hexose GO:0009746 144 0.014
defense response GO:0006952 194 0.014
Rat
regulation of neuron projection development GO:0010975 161 0.014
regulation of transcription dna templated GO:0006355 374 0.014
glucose homeostasis GO:0042593 75 0.014
positive regulation of transport GO:0051050 245 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
positive regulation of ion transport GO:0043270 94 0.013
cofactor biosynthetic process GO:0051188 28 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
programmed necrotic cell death GO:0097300 2 0.013
protein complex biogenesis GO:0070271 263 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
locomotion GO:0040011 237 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
regulation of growth GO:0040008 105 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to biotic stimulus GO:0009607 226 0.013
Rat
protein complex subunit organization GO:0071822 302 0.013
positive regulation of signaling GO:0023056 270 0.013
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
anion transport GO:0006820 178 0.013
ribonucleoside metabolic process GO:0009119 174 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
rna metabolic process GO:0016070 406 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
nucleotide metabolic process GO:0009117 279 0.012
nitrogen compound transport GO:0071705 229 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
cellular ketone metabolic process GO:0042180 51 0.012
response to nicotine GO:0035094 51 0.012
regulation of homeostatic process GO:0032844 101 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
positive regulation of developmental process GO:0051094 283 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
positive regulation of signal transduction GO:0009967 175 0.012
positive regulation of molecular function GO:0044093 230 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
multi organism reproductive process GO:0044703 262 0.012
response to hypoxia GO:0001666 231 0.012
Rat
male gamete generation GO:0048232 99 0.012
cellular response to peptide GO:1901653 133 0.012
response to other organism GO:0051707 220 0.012
Rat
positive regulation of cell development GO:0010720 176 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
regulation of protein metabolic process GO:0051246 289 0.012
xenobiotic catabolic process GO:0042178 7 0.011
regulation of calcium ion transmembrane transport GO:1903169 18 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
nucleic acid templated transcription GO:0097659 379 0.011
action potential GO:0001508 54 0.011
immune system process GO:0002376 204 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
Rat
cellular response to fluid shear stress GO:0071498 4 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
Rat
head development GO:0060322 247 0.011
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
cellular response to metal ion GO:0071248 55 0.011
jak stat cascade GO:0007259 26 0.011
response to lithium ion GO:0010226 28 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
neuron development GO:0048666 286 0.011
protein complex assembly GO:0006461 263 0.011
macromolecule localization GO:0033036 252 0.011
cellular component morphogenesis GO:0032989 155 0.011
Rat
regulation of cell projection organization GO:0031344 175 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regeneration GO:0031099 163 0.010
rna biosynthetic process GO:0032774 380 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
skeletal muscle cell differentiation GO:0035914 2 0.010
Rat
macromolecular complex subunit organization GO:0043933 339 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
spermatogenesis GO:0007283 99 0.010
negative regulation of cell communication GO:0010648 158 0.010
positive regulation of cell migration GO:0030335 96 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
response to growth factor GO:0070848 189 0.010
response to amine GO:0014075 46 0.010

S100a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.011
inherited metabolic disorder DOID:655 0 0.011