Rattus norvegicus

31 known processes

Cyp3a23/3a1

cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1

(Aliases: RL33,CYP,cDEX,CYP3A23,Cyp3a3,MGC108757,Cyp3a1)

Cyp3a23/3a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alkaloid metabolic process GO:0009820 3 0.915
Human
trichloroethylene metabolic process GO:0018979 1 0.878
response to cesium ion GO:0010164 2 0.841
naphthalene containing compound metabolic process GO:0090420 2 0.834
steroid metabolic process GO:0008202 73 0.730
Human Fly
chlorinated hydrocarbon metabolic process GO:0042196 4 0.691
response to xenobiotic stimulus GO:0009410 23 0.637
Zebrafish Fly
halogenated hydrocarbon metabolic process GO:0042197 4 0.637
response to extracellular stimulus GO:0009991 380 0.614
epoxygenase p450 pathway GO:0019373 1 0.581
nicotine metabolic process GO:0018933 1 0.568
cellular response to endogenous stimulus GO:0071495 377 0.525
acylglycerol metabolic process GO:0006639 21 0.521
cellular response to organic cyclic compound GO:0071407 202 0.506
cellular response to xenobiotic stimulus GO:0071466 19 0.467
Fly
monocarboxylic acid metabolic process GO:0032787 152 0.458
Fly
oxoacid metabolic process GO:0043436 290 0.441
Fly
naphthalene metabolic process GO:0018931 2 0.440
carboxylic acid metabolic process GO:0019752 289 0.426
Fly
neutral lipid metabolic process GO:0006638 21 0.370
lipid metabolic process GO:0006629 283 0.370
Human Fly
steroid biosynthetic process GO:0006694 48 0.347
Human Fly
4 nitrophenol metabolic process GO:0018960 1 0.246
fatty acid metabolic process GO:0006631 99 0.232
Fly
cellular response to lipid GO:0071396 201 0.225
response to estrogen GO:0043627 232 0.211
response to other organism GO:0051707 220 0.210
Fly
oxidation reduction process GO:0055114 304 0.203
response to peptide GO:1901652 292 0.196
response to insecticide GO:0017085 21 0.191
Fly
response to ethanol GO:0045471 162 0.188
response to nutrient GO:0007584 248 0.182
regulation of lipid biosynthetic process GO:0046890 38 0.177
lipid biosynthetic process GO:0008610 128 0.172
Human Fly
cellular response to hormone stimulus GO:0032870 247 0.166
calcitriol biosynthetic process from calciol GO:0036378 2 0.163
Human
small molecule catabolic process GO:0044282 59 0.161
response to sulfur dioxide GO:0010477 3 0.156
cellular ketone metabolic process GO:0042180 51 0.155
Fly
insecticide metabolic process GO:0017143 4 0.155
Fly
xenobiotic metabolic process GO:0006805 19 0.143
Fly
cellular response to oxygen containing compound GO:1901701 386 0.138
reproductive process GO:0022414 372 0.131
single organism catabolic process GO:0044712 283 0.131
Human Fly
response to acid chemical GO:0001101 222 0.127
response to external biotic stimulus GO:0043207 221 0.126
Fly
response to nutrient levels GO:0031667 370 0.126
pyridine containing compound metabolic process GO:0072524 32 0.124
drug catabolic process GO:0042737 1 0.116
Human
hepaticobiliary system development GO:0061008 90 0.115
icosanoid metabolic process GO:0006690 38 0.114
immune system process GO:0002376 204 0.114
drug metabolic process GO:0017144 11 0.108
anion transport GO:0006820 178 0.105
toxin catabolic process GO:0009407 1 0.103
Fly
hormone metabolic process GO:0042445 69 0.103
Fly
catabolic process GO:0009056 351 0.101
Human Fly
secondary metabolite catabolic process GO:0090487 1 0.101
Fly
response to biotic stimulus GO:0009607 226 0.099
Fly
response to bacterium GO:0009617 200 0.096
Fly
response to ddt GO:0046680 1 0.095
Fly
cellular amino acid metabolic process GO:0006520 107 0.093
response to lipopolysaccharide GO:0032496 191 0.092
reproduction GO:0000003 245 0.091
liver development GO:0001889 90 0.091
single organism reproductive process GO:0044702 297 0.090
triglyceride metabolic process GO:0006641 21 0.089
cellular response to organonitrogen compound GO:0071417 197 0.086
positive regulation of multicellular organismal process GO:0051240 387 0.086
Rat
response to peptide hormone GO:0043434 278 0.086
macromolecule localization GO:0033036 252 0.085
unsaturated fatty acid metabolic process GO:0033559 39 0.085
telencephalon development GO:0021537 62 0.082
isoprenoid metabolic process GO:0006720 45 0.082
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.081
cellular response to nitrogen compound GO:1901699 210 0.080
regulation of lipid metabolic process GO:0019216 68 0.080
response to corticosteroid GO:0031960 235 0.079
cellular hormone metabolic process GO:0034754 49 0.077
Fly
multicellular organism reproduction GO:0032504 233 0.076
catecholamine metabolic process GO:0006584 19 0.073
terpenoid metabolic process GO:0006721 37 0.073
Human
vitamin d biosynthetic process GO:0042368 2 0.068
Human
arachidonic acid metabolic process GO:0019369 20 0.067
organic substance catabolic process GO:1901575 316 0.064
Human
secondary metabolic process GO:0019748 15 0.064
Fly
protein phosphorylation GO:0006468 345 0.064
single organism biosynthetic process GO:0044711 342 0.064
Human Fly
cellular lipid metabolic process GO:0044255 208 0.063
Human Fly
organic acid biosynthetic process GO:0016053 83 0.062
organic hydroxy compound transport GO:0015850 77 0.061
regulation of secretion by cell GO:1903530 208 0.061
multi multicellular organism process GO:0044706 138 0.061
response to oxidative stress GO:0006979 186 0.058
response to organophosphorus GO:0046683 102 0.058
Fly
cellular nitrogen compound catabolic process GO:0044270 163 0.058
Human
multi organism reproductive process GO:0044703 262 0.057
transmembrane transport GO:0055085 412 0.056
bile acid and bile salt transport GO:0015721 12 0.055
organic acid metabolic process GO:0006082 292 0.055
Fly
response to molecule of bacterial origin GO:0002237 194 0.054
protein complex biogenesis GO:0070271 263 0.054
response to vitamin d GO:0033280 34 0.051
fatty acid derivative metabolic process GO:1901568 38 0.051
lipid catabolic process GO:0016042 46 0.051
Human
regulation of phosphate metabolic process GO:0019220 349 0.049
cellular response to alcohol GO:0097306 87 0.049
rhythmic process GO:0048511 156 0.049
vitamin d metabolic process GO:0042359 4 0.048
Human
multicellular organismal reproductive process GO:0048609 233 0.048
response to radiation GO:0009314 137 0.047
regulation of response to stress GO:0080134 126 0.046
peptidyl amino acid modification GO:0018193 126 0.045
long chain fatty acid metabolic process GO:0001676 32 0.045
catechol containing compound metabolic process GO:0009712 19 0.044
monocarboxylic acid transport GO:0015718 52 0.044
response to cytokine GO:0034097 215 0.042
biphenyl catabolic process GO:0070980 2 0.041
phenol containing compound metabolic process GO:0018958 30 0.041
regulation of immune system process GO:0002682 123 0.041
regulation of hormone levels GO:0010817 187 0.040
Fly
cellular response to nutrient levels GO:0031669 60 0.040
exogenous drug catabolic process GO:0042738 1 0.040
Human
response to purine containing compound GO:0014074 126 0.039
Fly
lipid localization GO:0010876 62 0.039
phenylpropanoid metabolic process GO:0009698 5 0.039
protein homooligomerization GO:0051260 91 0.038
intestinal absorption GO:0050892 3 0.038
macromolecular complex assembly GO:0065003 273 0.037
aging GO:0007568 241 0.037
protein complex assembly GO:0006461 263 0.037
coumarin metabolic process GO:0009804 5 0.037
negative regulation of transport GO:0051051 136 0.037
carboxylic acid transport GO:0046942 115 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
positive regulation of phosphorylation GO:0042327 177 0.036
positive regulation of protein kinase b signaling GO:0051897 10 0.035
glycerolipid metabolic process GO:0046486 67 0.034
cellular catabolic process GO:0044248 295 0.034
Human Fly
response to reactive oxygen species GO:0000302 120 0.033
peptidyl tyrosine modification GO:0018212 72 0.033
organonitrogen compound catabolic process GO:1901565 179 0.033
Human
organic hydroxy compound metabolic process GO:1901615 115 0.032
Human Fly
positive regulation of lipid catabolic process GO:0050996 4 0.032
establishment of protein localization GO:0045184 141 0.032
cellular response to extracellular stimulus GO:0031668 73 0.032
linoleic acid metabolic process GO:0043651 4 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
Human
diterpenoid metabolic process GO:0016101 33 0.031
heterocycle catabolic process GO:0046700 167 0.030
4 chlorobiphenyl metabolic process GO:0018880 1 0.030
ion transmembrane transport GO:0034220 365 0.030
regulation of phosphorylation GO:0042325 248 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
cellular component assembly GO:0022607 360 0.029
hormone biosynthetic process GO:0042446 25 0.029
Fly
development of primary sexual characteristics GO:0045137 107 0.029
small molecule biosynthetic process GO:0044283 124 0.028
Human Fly
female sex differentiation GO:0046660 59 0.028
regulation of catalytic activity GO:0050790 304 0.028
female pregnancy GO:0007565 122 0.028
regulation of molecular function GO:0065009 398 0.028
ovulation cycle GO:0042698 67 0.028
negative regulation of protein metabolic process GO:0051248 114 0.028
negative regulation of cellular protein metabolic process GO:0032269 106 0.027
progesterone metabolic process GO:0042448 8 0.027
negative regulation of metabolic process GO:0009892 331 0.027
cellular response to stress GO:0033554 269 0.027
regulation of system process GO:0044057 208 0.027
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
choline transport GO:0015871 4 0.026
response to vitamin GO:0033273 131 0.026
aromatic compound catabolic process GO:0019439 168 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
cellular amine metabolic process GO:0044106 38 0.025
carboxylic acid catabolic process GO:0046395 49 0.025
regeneration GO:0031099 163 0.025
regulation of cellular catabolic process GO:0031329 101 0.024
carbohydrate biosynthetic process GO:0016051 42 0.024
organic hydroxy compound biosynthetic process GO:1901617 51 0.024
Human Fly
testosterone biosynthetic process GO:0061370 5 0.024
reproductive structure development GO:0048608 128 0.024
peptidyl tyrosine phosphorylation GO:0018108 72 0.024
brain development GO:0007420 247 0.024
tetrapyrrole metabolic process GO:0033013 11 0.023
cellular response to vitamin d GO:0071305 12 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
regulation of protein kinase activity GO:0045859 105 0.023
positive regulation of lipid metabolic process GO:0045834 33 0.023
oxidative demethylation GO:0070989 2 0.023
cofactor metabolic process GO:0051186 95 0.023
canalicular bile acid transport GO:0015722 5 0.022
cellular response to peptide GO:1901653 133 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
monosaccharide metabolic process GO:0005996 61 0.022
circulatory system process GO:0003013 183 0.022
Rat
response to ketone GO:1901654 182 0.022
organic anion transport GO:0015711 132 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
organ regeneration GO:0031100 101 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
gonad development GO:0008406 104 0.020
positive regulation of lipid biosynthetic process GO:0046889 25 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
steroid catabolic process GO:0006706 5 0.020
Human
protein complex subunit organization GO:0071822 302 0.020
response to growth factor GO:0070848 189 0.020
secretion GO:0046903 307 0.020
muscle contraction GO:0006936 88 0.020
glycogen metabolic process GO:0005977 23 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
forebrain development GO:0030900 98 0.019
lipid transport GO:0006869 61 0.019
cellular macromolecule localization GO:0070727 122 0.019
blood circulation GO:0008015 183 0.019
Rat
regulation of protein metabolic process GO:0051246 289 0.019
monocarboxylic acid biosynthetic process GO:0072330 48 0.018
positive regulation of nervous system development GO:0051962 178 0.018
programmed cell death GO:0012501 392 0.018
catecholamine biosynthetic process GO:0042423 9 0.018
gamete generation GO:0007276 124 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
protein oligomerization GO:0051259 191 0.018
response to toxic substance GO:0009636 133 0.018
Fly
response to insulin GO:0032868 133 0.018
ras protein signal transduction GO:0007265 29 0.018
protein kinase b signaling GO:0043491 18 0.018
developmental process involved in reproduction GO:0003006 159 0.018
regulation of mapk cascade GO:0043408 116 0.018
alditol metabolic process GO:0019400 4 0.017
response to activity GO:0014823 73 0.017
sulfation GO:0051923 2 0.017
regulation of hormone secretion GO:0046883 106 0.017
cellular response to ketone GO:1901655 51 0.017
regulation of protein modification process GO:0031399 194 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
intracellular signal transduction GO:0035556 314 0.016
glycogen biosynthetic process GO:0005978 15 0.016
toxin metabolic process GO:0009404 9 0.016
Fly
protein localization GO:0008104 191 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
amide transport GO:0042886 105 0.016
jak stat cascade GO:0007259 26 0.016
parturition GO:0007567 10 0.016
regulation of nervous system development GO:0051960 264 0.016
defense response to gram negative bacterium GO:0050829 3 0.016
Fly
alcohol metabolic process GO:0006066 77 0.016
Human Fly
response to gonadotropin GO:0034698 34 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
organic acid catabolic process GO:0016054 49 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
defense response GO:0006952 194 0.015
Fly
glucan biosynthetic process GO:0009250 15 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
chemokine metabolic process GO:0050755 3 0.015
multicellular organismal homeostasis GO:0048871 49 0.015
transmission of nerve impulse GO:0019226 42 0.015
positive regulation of fatty acid beta oxidation GO:0032000 4 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
negative regulation of protein modification process GO:0031400 52 0.015
amine metabolic process GO:0009308 38 0.014
regulation of signal transduction GO:0009966 318 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
retinoid metabolic process GO:0001523 24 0.014
regulation of catabolic process GO:0009894 113 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.014
positive regulation of transport GO:0051050 245 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
growth GO:0040007 165 0.014
Fly
regulation of steroid metabolic process GO:0019218 25 0.014
response to hexose GO:0009746 144 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
activation of protein kinase b activity GO:0032148 3 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
c21 steroid hormone metabolic process GO:0008207 14 0.013
cellular response to external stimulus GO:0071496 118 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
Fly
response to lead ion GO:0010288 33 0.013
response to alkaloid GO:0043279 132 0.013
Fly
positive regulation of apoptotic process GO:0043065 154 0.013
developmental growth GO:0048589 100 0.013
Fly
response to metal ion GO:0010038 253 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
regulation of protein maturation GO:1903317 50 0.013
regulation of protein localization GO:0032880 81 0.013
multicellular organism growth GO:0035264 1 0.013
response to carbohydrate GO:0009743 183 0.013
negative regulation of gene expression GO:0010629 199 0.013
positive regulation of humoral immune response GO:0002922 2 0.013
norepinephrine metabolic process GO:0042415 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
response to estradiol GO:0032355 164 0.013
cell adhesion GO:0007155 110 0.013
response to camp GO:0051591 91 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.012
antral ovarian follicle growth GO:0001547 3 0.012
urea cycle GO:0000050 5 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
regulation of cell adhesion GO:0030155 52 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
male gamete generation GO:0048232 99 0.012
phenylpropanoid catabolic process GO:0046271 3 0.012
carbohydrate homeostasis GO:0033500 75 0.012
antibiotic transport GO:0042891 2 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
regulation of response to tumor cell GO:0002834 3 0.012
positive regulation of catabolic process GO:0009896 78 0.012
positive regulation of jak stat cascade GO:0046427 19 0.012
retinal metabolic process GO:0042574 3 0.012
negative regulation of molecular function GO:0044092 133 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
protein targeting to nucleus GO:0044744 35 0.012
response to mercury ion GO:0046689 15 0.012
Fly
neuron differentiation GO:0030182 368 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.012
porphyrin containing compound metabolic process GO:0006778 8 0.012
response to monosaccharide GO:0034284 159 0.012
negative regulation of gluconeogenesis GO:0045721 1 0.011
cellular response to nutrient GO:0031670 30 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
cellular response to vitamin GO:0071295 21 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
sterol catabolic process GO:0016127 1 0.011
response to ionizing radiation GO:0010212 59 0.011
cellular protein localization GO:0034613 122 0.011
organic acid transport GO:0015849 116 0.011
serine family amino acid biosynthetic process GO:0009070 4 0.011
cellular component biogenesis GO:0044085 368 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
platelet aggregation GO:0070527 4 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
action potential GO:0001508 54 0.011
sex differentiation GO:0007548 113 0.011
cellular aldehyde metabolic process GO:0006081 11 0.011
neuron development GO:0048666 286 0.011
cartilage condensation GO:0001502 2 0.011
regulation of peptide transport GO:0090087 87 0.011
cellular response to magnesium ion GO:0071286 4 0.011
neuron projection development GO:0031175 273 0.011
intracellular protein transport GO:0006886 79 0.010
response to calcium ion GO:0051592 59 0.010
regulation of neurogenesis GO:0050767 247 0.010
myoblast fusion GO:0007520 2 0.010
sorbitol biosynthetic process GO:0006061 1 0.010
glutathione biosynthetic process GO:0006750 3 0.010
b cell mediated immunity GO:0019724 4 0.010
bile acid secretion GO:0032782 5 0.010
polyol biosynthetic process GO:0046173 13 0.010
Human
negative regulation of neuron projection development GO:0010977 46 0.010
cellular response to fluid shear stress GO:0071498 4 0.010
regulation of neuron projection development GO:0010975 161 0.010
secondary alcohol metabolic process GO:1902652 2 0.010
Human
response to triglyceride GO:0034014 3 0.010
regulation of hydrolase activity GO:0051336 143 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010

Cyp3a23/3a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.027
disease of anatomical entity DOID:7 0 0.022
Human
vascular disease DOID:178 0 0.022
Human
cardiovascular system disease DOID:1287 0 0.022
Human
immune system disease DOID:2914 0 0.016
blood coagulation disease DOID:1247 0 0.016
inherited blood coagulation disease DOID:2214 0 0.016
hematopoietic system disease DOID:74 0 0.016
hypertension DOID:10763 0 0.015
Human
artery disease DOID:0050828 0 0.015
Human
essential hypertension DOID:10825 0 0.015
Human