Rattus norvegicus

0 known processes

Apbb3

amyloid beta (A4) precursor protein-binding, family B, member 3

(Aliases: Fe65l2)

Apbb3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
receptor metabolic process GO:0043112 18 0.133
secretion by cell GO:0032940 248 0.117
Rat
neuron differentiation GO:0030182 368 0.109
regulation of nervous system development GO:0051960 264 0.105
regulation of multicellular organismal development GO:2000026 376 0.098
regulation of secretion GO:0051046 224 0.094
Rat
cell projection organization GO:0030030 302 0.094
apoptotic process GO:0006915 381 0.092
organophosphate metabolic process GO:0019637 370 0.087
regulation of signal transduction GO:0009966 318 0.084
neuron development GO:0048666 286 0.081
regulation of cellular component organization GO:0051128 368 0.080
vesicle mediated transport GO:0016192 181 0.075
positive regulation of multicellular organismal process GO:0051240 387 0.075
organic substance catabolic process GO:1901575 316 0.072
regulation of molecular function GO:0065009 398 0.071
programmed cell death GO:0012501 392 0.070
catabolic process GO:0009056 351 0.068
macromolecule localization GO:0033036 252 0.067
Rat
cellular catabolic process GO:0044248 295 0.067
cell cell signaling GO:0007267 335 0.067
organelle organization GO:0006996 266 0.066
Rat
neuron projection development GO:0031175 273 0.065
axon development GO:0061564 96 0.063
cellular component movement GO:0006928 248 0.063
regulation of cell development GO:0060284 263 0.060
carboxylic acid metabolic process GO:0019752 289 0.058
cell projection morphogenesis GO:0048858 123 0.057
anatomical structure morphogenesis GO:0009653 298 0.056
regulation of nucleic acid templated transcription GO:1903506 380 0.056
Rat
response to nutrient levels GO:0031667 370 0.053
locomotion GO:0040011 237 0.053
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
single organism catabolic process GO:0044712 283 0.051
regulation of axonogenesis GO:0050770 37 0.051
regulation of neuron differentiation GO:0045664 208 0.051
organonitrogen compound catabolic process GO:1901565 179 0.050
cellular amino acid metabolic process GO:0006520 107 0.050
nucleoside phosphate metabolic process GO:0006753 283 0.049
synaptic transmission GO:0007268 235 0.048
negative regulation of multicellular organismal process GO:0051241 203 0.048
oxoacid metabolic process GO:0043436 290 0.048
intracellular transport GO:0046907 185 0.047
organic acid metabolic process GO:0006082 292 0.047
secretion GO:0046903 307 0.047
Rat
regulation of cellular localization GO:0060341 263 0.045
Rat
regulation of cell differentiation GO:0045595 320 0.045
protein localization GO:0008104 191 0.045
Rat
cellular response to stress GO:0033554 269 0.045
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.044
cellular lipid metabolic process GO:0044255 208 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.043
purine ribonucleotide metabolic process GO:0009150 227 0.043
endocytosis GO:0006897 84 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
neuron projection morphogenesis GO:0048812 122 0.042
macromolecular complex subunit organization GO:0043933 339 0.041
Rat
organophosphate catabolic process GO:0046434 148 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.041
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.040
regulation of neurogenesis GO:0050767 247 0.040
transcription dna templated GO:0006351 377 0.039
Rat
positive regulation of transport GO:0051050 245 0.039
Rat
cellular component biogenesis GO:0044085 368 0.039
protein phosphorylation GO:0006468 345 0.039
regulation of programmed cell death GO:0043067 341 0.039
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
nucleotide metabolic process GO:0009117 279 0.038
response to nutrient GO:0007584 248 0.038
purine containing compound metabolic process GO:0072521 253 0.038
establishment of protein localization GO:0045184 141 0.038
Rat
membrane organization GO:0061024 94 0.037
cellular amine metabolic process GO:0044106 38 0.037
amine metabolic process GO:0009308 38 0.037
regulation of rna metabolic process GO:0051252 391 0.036
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.036
growth GO:0040007 165 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
purine nucleoside triphosphate catabolic process GO:0009146 122 0.035
axonogenesis GO:0007409 71 0.035
regulation of catabolic process GO:0009894 113 0.035
intracellular signal transduction GO:0035556 314 0.035
cellular component assembly GO:0022607 360 0.034
cell motility GO:0048870 202 0.034
response to extracellular stimulus GO:0009991 380 0.034
rna biosynthetic process GO:0032774 380 0.034
Rat
regulation of apoptotic process GO:0042981 335 0.033
ribose phosphate metabolic process GO:0019693 235 0.033
ribonucleoside catabolic process GO:0042454 126 0.032
small gtpase mediated signal transduction GO:0007264 36 0.032
nucleoside triphosphate metabolic process GO:0009141 144 0.032
single organism intracellular transport GO:1902582 166 0.032
response to inorganic substance GO:0010035 377 0.032
Rat
regulation of catalytic activity GO:0050790 304 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
Rat
cellular protein localization GO:0034613 122 0.032
positive regulation of developmental process GO:0051094 283 0.031
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
protein transport GO:0015031 132 0.031
Rat
receptor mediated endocytosis GO:0006898 42 0.031
purine nucleotide metabolic process GO:0006163 229 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
regulation of neuron projection development GO:0010975 161 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
cell morphogenesis involved in differentiation GO:0000904 119 0.030
purine nucleotide catabolic process GO:0006195 136 0.030
g protein coupled receptor signaling pathway GO:0007186 242 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
purine containing compound catabolic process GO:0072523 138 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
Rat
regulation of secretion by cell GO:1903530 208 0.029
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
nucleoside metabolic process GO:0009116 179 0.028
regulation of transcription dna templated GO:0006355 374 0.028
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
localization of cell GO:0051674 202 0.027
actin filament based process GO:0030029 86 0.027
multicellular organism reproduction GO:0032504 233 0.027
negative regulation of metabolic process GO:0009892 331 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
Rat
regulation of cell projection organization GO:0031344 175 0.027
cell morphogenesis GO:0000902 142 0.027
regulation of rna biosynthetic process GO:2001141 381 0.026
Rat
positive regulation of cell differentiation GO:0045597 217 0.026
rna metabolic process GO:0016070 406 0.026
Rat
cellular ketone metabolic process GO:0042180 51 0.026
nucleoside triphosphate catabolic process GO:0009143 123 0.026
positive regulation of secretion by cell GO:1903532 128 0.026
Rat
cell part morphogenesis GO:0032990 123 0.026
aging GO:0007568 241 0.026
cellular component morphogenesis GO:0032989 155 0.026
purine nucleoside metabolic process GO:0042278 169 0.025
protein complex subunit organization GO:0071822 302 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.025
carbohydrate derivative catabolic process GO:1901136 147 0.025
proteolysis GO:0006508 175 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
response to wounding GO:0009611 254 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
response to monosaccharide GO:0034284 159 0.024
ribonucleotide catabolic process GO:0009261 136 0.024
response to hexose GO:0009746 144 0.024
regulation of growth GO:0040008 105 0.024
response to growth factor GO:0070848 189 0.024
regulation of nucleotide metabolic process GO:0006140 117 0.024
negative regulation of neurogenesis GO:0050768 78 0.024
response to peptide hormone GO:0043434 278 0.023
response to hypoxia GO:0001666 231 0.023
reproduction GO:0000003 245 0.023
single organism biosynthetic process GO:0044711 342 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
reproductive process GO:0022414 372 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
positive regulation of neuron differentiation GO:0045666 126 0.022
positive regulation of molecular function GO:0044093 230 0.022
gtp catabolic process GO:0006184 71 0.022
hormone transport GO:0009914 121 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
ras protein signal transduction GO:0007265 29 0.022
positive regulation of cell death GO:0010942 184 0.022
positive regulation of cell development GO:0010720 176 0.022
macromolecular complex assembly GO:0065003 273 0.022
regulation of protein metabolic process GO:0051246 289 0.022
metal ion transport GO:0030001 289 0.021
cellular homeostasis GO:0019725 252 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
response to external biotic stimulus GO:0043207 221 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.021
negative regulation of cell death GO:0060548 229 0.021
neuron death GO:0070997 127 0.021
cell type specific apoptotic process GO:0097285 134 0.021
response to glucose GO:0009749 136 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
chemotaxis GO:0006935 66 0.021
glycosyl compound catabolic process GO:1901658 126 0.021
regulation of membrane potential GO:0042391 110 0.021
phospholipid metabolic process GO:0006644 61 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
developmental process involved in reproduction GO:0003006 159 0.020
nucleic acid templated transcription GO:0097659 379 0.020
Rat
response to peptide GO:1901652 292 0.020
cellular macromolecule localization GO:0070727 122 0.020
carboxylic acid biosynthetic process GO:0046394 83 0.020
nucleotide catabolic process GO:0009166 139 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
lipid metabolic process GO:0006629 283 0.020
gtp metabolic process GO:0046039 72 0.020
actin cytoskeleton organization GO:0030036 73 0.020
negative regulation of developmental process GO:0051093 125 0.020
single organism cellular localization GO:1902580 102 0.020
positive regulation of signaling GO:0023056 270 0.020
multi organism reproductive process GO:0044703 262 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
Rat
positive regulation of neurogenesis GO:0050769 165 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
embryonic pattern specification GO:0009880 1 0.020
positive regulation of nervous system development GO:0051962 178 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
multicellular organism growth GO:0035264 1 0.019
response to alkaloid GO:0043279 132 0.019
lipid modification GO:0030258 52 0.019
tissue development GO:0009888 252 0.019
cytoplasmic transport GO:0016482 115 0.019
response to metal ion GO:0010038 253 0.019
Rat
protein autophosphorylation GO:0046777 66 0.019
regulation of hydrolase activity GO:0051336 143 0.019
negative regulation of nervous system development GO:0051961 79 0.019
heterocycle catabolic process GO:0046700 167 0.019
adult locomotory behavior GO:0008344 4 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
protein complex assembly GO:0006461 263 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.018
signal release GO:0023061 145 0.018
negative regulation of molecular function GO:0044092 133 0.018
protein oligomerization GO:0051259 191 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
protein complex biogenesis GO:0070271 263 0.018
brain development GO:0007420 247 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
negative regulation of cell development GO:0010721 82 0.017
nucleoside catabolic process GO:0009164 126 0.017
response to decreased oxygen levels GO:0036293 237 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.017
negative regulation of gene expression GO:0010629 199 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
cytoskeleton dependent cytokinesis GO:0061640 2 0.017
single organism organelle organization GO:1902589 180 0.017
Rat
homeostatic process GO:0042592 331 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
Rat
cardiovascular system development GO:0072358 134 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
Rat
response to insulin GO:0032868 133 0.017
regulation of small gtpase mediated signal transduction GO:0051056 48 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.016
regulation of cell growth GO:0001558 85 0.016
peptidyl amino acid modification GO:0018193 126 0.016
Rat
single organism reproductive process GO:0044702 297 0.016
aromatic compound catabolic process GO:0019439 168 0.016
positive regulation of gene expression GO:0010628 244 0.016
Rat
cell migration GO:0016477 197 0.016
regulation of gtpase activity GO:0043087 57 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
Rat
cell growth GO:0016049 104 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of secretion GO:0051047 140 0.016
Rat
axis specification GO:0009798 4 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
nitrogen compound transport GO:0071705 229 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
cytoskeleton organization GO:0007010 111 0.016
chemical homeostasis GO:0048878 292 0.016
ion transmembrane transport GO:0034220 365 0.016
cellular chemical homeostasis GO:0055082 247 0.016
gamete generation GO:0007276 124 0.016
regulation of protein modification process GO:0031399 194 0.016
regulation of rab protein signal transduction GO:0032483 3 0.016
synapse organization GO:0050808 46 0.016
response to oxidative stress GO:0006979 186 0.016
response to biotic stimulus GO:0009607 226 0.015
response to carbohydrate GO:0009743 183 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
regulation of anatomical structure size GO:0090066 135 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
organ morphogenesis GO:0009887 75 0.015
regulation of system process GO:0044057 208 0.015
response to temperature stimulus GO:0009266 94 0.015
response to lipopolysaccharide GO:0032496 191 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
response to other organism GO:0051707 220 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
alcohol metabolic process GO:0006066 77 0.015
negative regulation of transport GO:0051051 136 0.015
regeneration GO:0031099 163 0.015
axon guidance GO:0007411 24 0.014
glycerophospholipid metabolic process GO:0006650 47 0.014
developmental growth GO:0048589 100 0.014
regulation of developmental growth GO:0048638 45 0.014
response to acid chemical GO:0001101 222 0.014
regulation of cell migration GO:0030334 128 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
taxis GO:0042330 67 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
heart morphogenesis GO:0003007 3 0.014
regulation of synapse structure and activity GO:0050803 21 0.014
positive regulation of catabolic process GO:0009896 78 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
single organism membrane organization GO:0044802 74 0.014
regulation of nucleoside metabolic process GO:0009118 66 0.014
regulation of hormone secretion GO:0046883 106 0.014
exocytosis GO:0006887 60 0.014
sexual reproduction GO:0019953 148 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
spindle organization GO:0007051 2 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
neuron apoptotic process GO:0051402 88 0.014
head development GO:0060322 247 0.014
central nervous system development GO:0007417 311 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
bmp signaling pathway GO:0030509 4 0.014
response to cytokine GO:0034097 215 0.014
negative regulation of cell communication GO:0010648 158 0.014
response to purine containing compound GO:0014074 126 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
response to oxygen levels GO:0070482 265 0.014
behavior GO:0007610 205 0.014
regulation of protein kinase activity GO:0045859 105 0.014
small molecule biosynthetic process GO:0044283 124 0.014
regulation of cell motility GO:2000145 131 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of phosphorylation GO:0042325 248 0.013
intracellular protein transport GO:0006886 79 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
Rat
cellular ion homeostasis GO:0006873 184 0.013
regulation of hormone levels GO:0010817 187 0.013
synaptic vesicle endocytosis GO:0048488 4 0.013
anion transport GO:0006820 178 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
neuronal ion channel clustering GO:0045161 3 0.013
response to radiation GO:0009314 137 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
neurological system process GO:0050877 219 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of cell proliferation GO:0042127 359 0.013
cytokinetic process GO:0032506 1 0.013
hormone secretion GO:0046879 115 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
insulin secretion GO:0030073 69 0.012
dephosphorylation GO:0016311 98 0.012
positive regulation of protein modification process GO:0031401 142 0.012
cellular component maintenance GO:0043954 4 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
glycerolipid metabolic process GO:0046486 67 0.012
olfactory behavior GO:0042048 2 0.012
regulation of cellular component movement GO:0051270 150 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
cognition GO:0050890 92 0.012
response to bacterium GO:0009617 200 0.012
peptide secretion GO:0002790 86 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
transmembrane transport GO:0055085 412 0.012
gland development GO:0048732 155 0.012
defense response GO:0006952 194 0.012
cofactor metabolic process GO:0051186 95 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
immune system process GO:0002376 204 0.011
phosphatidylinositol dephosphorylation GO:0046856 4 0.011
establishment of vesicle localization GO:0051650 31 0.011
cellular cation homeostasis GO:0030003 180 0.011
regulation of kinase activity GO:0043549 117 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cellular response to peptide GO:1901653 133 0.011
regulation of organelle organization GO:0033043 80 0.011
response to ammonium ion GO:0060359 71 0.011
regulation of neuron death GO:1901214 115 0.011
positive regulation of cell communication GO:0010647 271 0.011
rho protein signal transduction GO:0007266 11 0.011
coenzyme metabolic process GO:0006732 86 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
circulatory system process GO:0003013 183 0.011
oxidation reduction process GO:0055114 304 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
lipid biosynthetic process GO:0008610 128 0.011
reproductive structure development GO:0048608 128 0.011
cation transport GO:0006812 382 0.011
protein localization to membrane GO:0072657 36 0.011
response to reactive oxygen species GO:0000302 120 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
synaptic vesicle localization GO:0097479 24 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
cell cycle checkpoint GO:0000075 2 0.011
neural crest cell development GO:0014032 2 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
rna localization GO:0006403 4 0.011
positive regulation of hydrolase activity GO:0051345 86 0.010
regulation of transmembrane transport GO:0034762 122 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
regulation of ras protein signal transduction GO:0046578 45 0.010
regulation of transferase activity GO:0051338 123 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
positive regulation of nucleotide catabolic process GO:0030813 53 0.010
appendage morphogenesis GO:0035107 4 0.010
eye morphogenesis GO:0048592 4 0.010
glial cell differentiation GO:0010001 65 0.010
cation homeostasis GO:0055080 195 0.010
establishment of organelle localization GO:0051656 37 0.010
regulation of telomerase activity GO:0051972 2 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
response to organophosphorus GO:0046683 102 0.010
rab protein signal transduction GO:0032482 1 0.010
double strand break repair GO:0006302 1 0.010
Rat
salivary gland development GO:0007431 3 0.010
blood circulation GO:0008015 183 0.010

Apbb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.012