Rattus norvegicus

0 known processes

Actn1

actinin, alpha 1

Actn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 86 0.374
Mouse Fly
cytoskeleton organization GO:0007010 111 0.334
Mouse Fly
single organism organelle organization GO:1902589 180 0.254
Mouse Fly
organelle organization GO:0006996 266 0.254
Mouse Fly
actin crosslink formation GO:0051764 3 0.182
cellular component biogenesis GO:0044085 368 0.180
Human Mouse Fly
cellular component morphogenesis GO:0032989 155 0.163
Fly
actin cytoskeleton organization GO:0030036 73 0.133
Mouse Fly
transcription dna templated GO:0006351 377 0.108
mrna transcription GO:0009299 2 0.101
cell motility GO:0048870 202 0.098
organic acid metabolic process GO:0006082 292 0.084
actin filament organization GO:0007015 42 0.082
Mouse
macromolecular complex subunit organization GO:0043933 339 0.077
Mouse
localization of cell GO:0051674 202 0.076
protein complex subunit organization GO:0071822 302 0.071
Mouse
neuron differentiation GO:0030182 368 0.070
protein phosphorylation GO:0006468 345 0.068
neuron projection development GO:0031175 273 0.066
neuron projection morphogenesis GO:0048812 122 0.065
cell projection organization GO:0030030 302 0.065
regulation of cell differentiation GO:0045595 320 0.063
cell morphogenesis involved in differentiation GO:0000904 119 0.061
blood circulation GO:0008015 183 0.060
cellular component movement GO:0006928 248 0.060
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.059
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.058
cation transport GO:0006812 382 0.057
single organism catabolic process GO:0044712 283 0.056
regulation of cytoskeleton organization GO:0051493 49 0.055
regulation of cellular protein metabolic process GO:0032268 267 0.055
protein complex assembly GO:0006461 263 0.055
response to decreased oxygen levels GO:0036293 237 0.054
Rat
organic anion transport GO:0015711 132 0.054
circulatory system process GO:0003013 183 0.054
regulation of multicellular organismal development GO:2000026 376 0.054
cellular nitrogen compound catabolic process GO:0044270 163 0.054
tissue development GO:0009888 252 0.053
dendrite development GO:0016358 72 0.053
muscle system process GO:0003012 115 0.052
cellular response to stress GO:0033554 269 0.051
purine nucleoside catabolic process GO:0006152 124 0.050
negative regulation of macromolecule metabolic process GO:0010605 260 0.050
oxoacid metabolic process GO:0043436 290 0.048
mrna transcription from rna polymerase ii promoter GO:0042789 1 0.047
locomotion GO:0040011 237 0.047
actomyosin structure organization GO:0031032 22 0.045
Fly
protein complex biogenesis GO:0070271 263 0.045
cellular ketone metabolic process GO:0042180 51 0.044
cell part morphogenesis GO:0032990 123 0.044
aging GO:0007568 241 0.044
cell cell signaling GO:0007267 335 0.043
regulation of molecular function GO:0065009 398 0.043
regulation of cellular component organization GO:0051128 368 0.042
cell projection morphogenesis GO:0048858 123 0.041
cell morphogenesis GO:0000902 142 0.041
anion transport GO:0006820 178 0.041
cellular amino acid metabolic process GO:0006520 107 0.039
negative regulation of signaling GO:0023057 157 0.039
immune system process GO:0002376 204 0.039
positive regulation of multicellular organismal process GO:0051240 387 0.039
positive regulation of programmed cell death GO:0043068 157 0.039
carboxylic acid metabolic process GO:0019752 289 0.037
response to oxygen levels GO:0070482 265 0.037
Rat
regulation of cell development GO:0060284 263 0.037
single organism cellular localization GO:1902580 102 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.036
purine nucleoside metabolic process GO:0042278 169 0.036
ion transmembrane transport GO:0034220 365 0.036
regulation of response to wounding GO:1903034 69 0.036
nucleic acid templated transcription GO:0097659 379 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.034
renal filtration GO:0097205 10 0.034
cellular component assembly GO:0022607 360 0.034
Human Mouse Fly
intracellular signal transduction GO:0035556 314 0.034
response to wounding GO:0009611 254 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
Fly
dendrite morphogenesis GO:0048813 43 0.033
actin filament bundle organization GO:0061572 19 0.033
Mouse
nucleotide metabolic process GO:0009117 279 0.033
actin filament bundle assembly GO:0051017 19 0.032
Mouse
regulation of protein metabolic process GO:0051246 289 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
defense response GO:0006952 194 0.032
negative regulation of metabolic process GO:0009892 331 0.032
neuron development GO:0048666 286 0.032
catabolic process GO:0009056 351 0.032
cellular response to oxygen containing compound GO:1901701 386 0.031
reproductive process GO:0022414 372 0.031
multicellular organismal reproductive process GO:0048609 233 0.030
regulation of ion transport GO:0043269 245 0.030
positive regulation of developmental process GO:0051094 283 0.030
regulation of cell projection organization GO:0031344 175 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.029
muscle structure development GO:0061061 87 0.029
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
secretion by cell GO:0032940 248 0.029
apoptotic process GO:0006915 381 0.029
Rat
epithelium development GO:0060429 96 0.029
regulation of rna metabolic process GO:0051252 391 0.028
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
heart process GO:0003015 57 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
leukocyte activation GO:0045321 76 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
ribonucleotide catabolic process GO:0009261 136 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
regulation of cellular component biogenesis GO:0044087 86 0.027
heart contraction GO:0060047 57 0.026
regulation of cellular component movement GO:0051270 150 0.026
Human
nitrogen compound transport GO:0071705 229 0.026
divalent inorganic cation transport GO:0072511 134 0.026
regulation of organelle organization GO:0033043 80 0.026
regulation of protein phosphorylation GO:0001932 183 0.025
negative regulation of actin filament polymerization GO:0030837 4 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
cellular homeostasis GO:0019725 252 0.025
regulation of locomotion GO:0040012 148 0.025
organic substance catabolic process GO:1901575 316 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
regulation of transcription dna templated GO:0006355 374 0.025
negative regulation of cell communication GO:0010648 158 0.024
response to starvation GO:0042594 59 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
positive regulation of signaling GO:0023056 270 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
regulation of anatomical structure size GO:0090066 135 0.024
organophosphate metabolic process GO:0019637 370 0.024
cardiac muscle contraction GO:0060048 27 0.024
macromolecule localization GO:0033036 252 0.024
regulation of nucleotide metabolic process GO:0006140 117 0.023
positive regulation of cell communication GO:0010647 271 0.023
protein targeting GO:0006605 61 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
carboxylic acid transport GO:0046942 115 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
response to growth factor GO:0070848 189 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
positive regulation of cellular component biogenesis GO:0044089 55 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
response to inorganic substance GO:0010035 377 0.022
positive regulation of synaptic transmission GO:0050806 62 0.022
positive regulation of cell death GO:0010942 184 0.022
regulation of cell morphogenesis GO:0022604 77 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
cellular catabolic process GO:0044248 295 0.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.022
negative regulation of molecular function GO:0044092 133 0.022
purine containing compound metabolic process GO:0072521 253 0.022
regulation of blood circulation GO:1903522 110 0.021
cation homeostasis GO:0055080 195 0.021
regulation of signal transduction GO:0009966 318 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of immunoglobulin production GO:0002639 4 0.021
nucleoside monophosphate metabolic process GO:0009123 93 0.021
secretion GO:0046903 307 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
response to nutrient levels GO:0031667 370 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.020
single organism biosynthetic process GO:0044711 342 0.020
regulation of apoptotic process GO:0042981 335 0.020
Rat
ribonucleoside metabolic process GO:0009119 174 0.020
purine nucleoside monophosphate metabolic process GO:0009126 84 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
regulation of synaptic transmission GO:0050804 141 0.020
cell cycle GO:0007049 101 0.020
regulation of secretion by cell GO:1903530 208 0.020
cellular protein complex assembly GO:0043623 44 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.019
regulation of purine nucleotide catabolic process GO:0033121 65 0.019
protein targeting to nucleus GO:0044744 35 0.019
aromatic compound catabolic process GO:0019439 168 0.019
positive regulation of cellular component movement GO:0051272 102 0.019
regulation of catabolic process GO:0009894 113 0.019
central nervous system development GO:0007417 311 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
amino acid transport GO:0006865 70 0.019
reproduction GO:0000003 245 0.019
ribonucleoside monophosphate catabolic process GO:0009158 55 0.019
regulation of neuron projection development GO:0010975 161 0.019
response to hypoxia GO:0001666 231 0.019
Rat
cellular response to cytokine stimulus GO:0071345 127 0.019
regulation of response to stress GO:0080134 126 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
positive regulation of cytoskeleton organization GO:0051495 26 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
oxidation reduction process GO:0055114 304 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
actin filament polymerization GO:0030041 11 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
stress activated protein kinase signaling cascade GO:0031098 37 0.017
response to oxidative stress GO:0006979 186 0.017
positive regulation of protein modification process GO:0031401 142 0.017
striated muscle cell development GO:0055002 26 0.017
Fly
macromolecular complex assembly GO:0065003 273 0.017
platelet aggregation GO:0070527 4 0.017
regulation of protein complex assembly GO:0043254 33 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cell migration GO:0016477 197 0.017
calcium ion homeostasis GO:0055074 162 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
cellular amine metabolic process GO:0044106 38 0.017
regulation of cell motility GO:2000145 131 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
rna metabolic process GO:0016070 406 0.016
programmed cell death GO:0012501 392 0.016
Rat
cardiovascular system development GO:0072358 134 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
regulation of actin filament based process GO:0032970 42 0.016
cytoplasmic transport GO:0016482 115 0.016
coagulation GO:0050817 28 0.016
calcium ion transport GO:0006816 131 0.016
cation transmembrane transport GO:0098655 263 0.016
metal ion transport GO:0030001 289 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
single organism intracellular transport GO:1902582 166 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
heterocycle catabolic process GO:0046700 167 0.016
regulation of cellular response to stress GO:0080135 49 0.016
positive regulation of gene expression GO:0010628 244 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.015
inflammatory response GO:0006954 150 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
response to hexose GO:0009746 144 0.015
intracellular transport GO:0046907 185 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
heterotypic cell cell adhesion GO:0034113 2 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
cellular response to peptide GO:1901653 133 0.015
axis specification GO:0009798 4 0.015
nucleotide catabolic process GO:0009166 139 0.015
nucleoside metabolic process GO:0009116 179 0.015
regulation of nucleotide catabolic process GO:0030811 65 0.015
positive regulation of blood coagulation GO:0030194 4 0.015
positive regulation of cell development GO:0010720 176 0.015
multi organism reproductive process GO:0044703 262 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.015
protein oligomerization GO:0051259 191 0.015
regulation of neurogenesis GO:0050767 247 0.015
cell cycle process GO:0022402 57 0.015
development of primary sexual characteristics GO:0045137 107 0.015
negative regulation of atp catabolic process GO:1903290 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
purine containing compound catabolic process GO:0072523 138 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
Fly
regulation of protein polymerization GO:0032271 19 0.014
regulation of transmembrane transport GO:0034762 122 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
actin filament depolymerization GO:0030042 3 0.014
regulation of dendrite morphogenesis GO:0048814 33 0.014
regulation of protein modification process GO:0031399 194 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
regulation of cell cycle GO:0051726 73 0.014
muscle contraction GO:0006936 88 0.014
positive regulation of molecular function GO:0044093 230 0.014
protein localization to organelle GO:0033365 57 0.014
regulation of muscle system process GO:0090257 79 0.014
response to cytokine GO:0034097 215 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
positive regulation of cell adhesion GO:0045785 30 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
ventricular cardiac muscle cell development GO:0055015 2 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
intracellular protein transport GO:0006886 79 0.013
ion homeostasis GO:0050801 212 0.013
ras protein signal transduction GO:0007265 29 0.013
divalent metal ion transport GO:0070838 132 0.013
regulation of actin filament depolymerization GO:0030834 2 0.013
regulation of actin polymerization or depolymerization GO:0008064 12 0.013
axon development GO:0061564 96 0.013
regulation of body fluid levels GO:0050878 90 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
protein localization GO:0008104 191 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of neuron differentiation GO:0045664 208 0.013
muscle cell proliferation GO:0033002 84 0.013
response to extracellular stimulus GO:0009991 380 0.013
sequestering of calcium ion GO:0051208 8 0.013
hormone secretion GO:0046879 115 0.013
wound healing GO:0042060 122 0.013
central nervous system neuron axonogenesis GO:0021955 1 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
response to toxic substance GO:0009636 133 0.013
macromolecule catabolic process GO:0009057 58 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
gonad development GO:0008406 104 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
striated muscle contraction GO:0006941 44 0.013
protein transport GO:0015031 132 0.013
establishment of protein localization to organelle GO:0072594 44 0.013
embryonic pattern specification GO:0009880 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
response to carbohydrate GO:0009743 183 0.012
regulation of cell migration GO:0030334 128 0.012
immune system development GO:0002520 41 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
organic acid transport GO:0015849 116 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
negative regulation of actin filament depolymerization GO:0030835 2 0.012
anterior posterior pattern specification GO:0009952 1 0.012
male gamete generation GO:0048232 99 0.012
regulation of actin cytoskeleton organization GO:0032956 30 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
cytokine mediated signaling pathway GO:0019221 43 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
generation of precursor metabolites and energy GO:0006091 62 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
negative regulation of neuron death GO:1901215 69 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
jnk cascade GO:0007254 28 0.012
smooth muscle contraction GO:0006939 37 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
immune response GO:0006955 104 0.012
biological adhesion GO:0022610 110 0.012
Human
dephosphorylation GO:0016311 98 0.012
motor neuron axon guidance GO:0008045 1 0.012
regulation of cellular component size GO:0032535 51 0.012
regulation of peptide secretion GO:0002791 82 0.012
positive regulation of immune system process GO:0002684 90 0.012
circulatory system development GO:0072359 134 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
lipid metabolic process GO:0006629 283 0.011
response to metal ion GO:0010038 253 0.011
calcium ion transport into cytosol GO:0060402 38 0.011
leukocyte migration GO:0050900 38 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
regulation of cell proliferation GO:0042127 359 0.011
regulation of hormone levels GO:0010817 187 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
regulation of nervous system development GO:0051960 264 0.011
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.011
regulation of immune system process GO:0002682 123 0.011
sequestering of metal ion GO:0051238 9 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of secretion GO:0051046 224 0.011
protein import GO:0017038 37 0.011
chemotaxis GO:0006935 66 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
gamete generation GO:0007276 124 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
cell substrate adhesion GO:0031589 29 0.011
Human
actin polymerization or depolymerization GO:0008154 14 0.011
regulation of cellular localization GO:0060341 263 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
rna localization GO:0006403 4 0.011
regulation of actin filament length GO:0030832 12 0.011
mapk cascade GO:0000165 140 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of hydrolase activity GO:0051336 143 0.011
synaptic transmission GO:0007268 235 0.011
regulation of transporter activity GO:0032409 50 0.010
developmental maturation GO:0021700 25 0.010
homeostatic process GO:0042592 331 0.010
response to insulin GO:0032868 133 0.010
regulation of dendrite development GO:0050773 59 0.010
establishment of planar polarity GO:0001736 1 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
regulation of phosphorylation GO:0042325 248 0.010
atp metabolic process GO:0046034 72 0.010
regulation of heart contraction GO:0008016 48 0.010
positive regulation of ossification GO:0045778 17 0.010
acute inflammatory response GO:0002526 58 0.010
regulation of peptide transport GO:0090087 87 0.010
negative regulation of gene expression GO:0010629 199 0.010

Actn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
urinary system disease DOID:18 0 0.028
cardiovascular system disease DOID:1287 0 0.018
epilepsy syndrome DOID:1826 0 0.017
central nervous system disease DOID:331 0 0.017
brain disease DOID:936 0 0.017
neuromuscular disease DOID:440 0 0.016
charcot marie tooth disease DOID:10595 0 0.016
neuropathy DOID:870 0 0.016
nephritis DOID:10952 0 0.016
kidney disease DOID:557 0 0.016
electroclinical syndrome DOID:0050701 0 0.012
neonatal period electroclinical syndrome DOID:0050702 0 0.012