Rattus norvegicus

0 known processes

Aifm3

apoptosis-inducing factor, mitochondrion-associated 3

(Aliases: MGC109275,RGD1306028)

Aifm3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 247 0.180
nitrogen compound transport GO:0071705 229 0.141
cation transport GO:0006812 382 0.084
central nervous system development GO:0007417 311 0.081
neuron neuron synaptic transmission GO:0007270 60 0.079
learning or memory GO:0007611 90 0.076
cellular response to nitrogen compound GO:1901699 210 0.072
programmed cell death GO:0012501 392 0.072
transmembrane transport GO:0055085 412 0.071
carboxylic acid metabolic process GO:0019752 289 0.070
response to peptide hormone GO:0043434 278 0.069
reproductive process GO:0022414 372 0.063
cation transmembrane transport GO:0098655 263 0.061
response to transition metal nanoparticle GO:1990267 122 0.061
inner ear receptor cell differentiation GO:0060113 2 0.060
response to extracellular stimulus GO:0009991 380 0.060
response to growth factor GO:0070848 189 0.054
single organism reproductive process GO:0044702 297 0.053
cellular response to peptide GO:1901653 133 0.052
cellular chemical homeostasis GO:0055082 247 0.047
regulation of signal transduction GO:0009966 318 0.046
organic acid metabolic process GO:0006082 292 0.046
regulation of secretion by cell GO:1903530 208 0.046
homeostatic process GO:0042592 331 0.046
behavior GO:0007610 205 0.045
cellular response to lipid GO:0071396 201 0.045
organic acid transport GO:0015849 116 0.044
rhythmic process GO:0048511 156 0.044
cellular response to endogenous stimulus GO:0071495 377 0.044
neurotransmitter transport GO:0006836 42 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
regulation of programmed cell death GO:0043067 341 0.040
brain development GO:0007420 247 0.037
development of primary sexual characteristics GO:0045137 107 0.037
positive regulation of secretion GO:0051047 140 0.035
cell migration GO:0016477 197 0.034
cellular response to organic cyclic compound GO:0071407 202 0.034
cellular response to growth factor stimulus GO:0071363 162 0.034
memory GO:0007613 54 0.034
anion transmembrane transport GO:0098656 77 0.033
negative regulation of cell death GO:0060548 229 0.033
amine transport GO:0015837 57 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
positive regulation of cell communication GO:0010647 271 0.033
signal transduction by phosphorylation GO:0023014 144 0.032
regulation of rna biosynthetic process GO:2001141 381 0.031
anion transport GO:0006820 178 0.031
signal release GO:0023061 145 0.031
learning GO:0007612 33 0.031
neurological system process GO:0050877 219 0.031
mapk cascade GO:0000165 140 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
telencephalon development GO:0021537 62 0.028
response to acid chemical GO:0001101 222 0.027
positive regulation of nervous system development GO:0051962 178 0.027
positive regulation of protein modification process GO:0031401 142 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of cellular localization GO:0060341 263 0.027
inorganic cation transmembrane transport GO:0098662 202 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
response to zinc ion GO:0010043 39 0.027
hormone transport GO:0009914 121 0.026
positive regulation of signaling GO:0023056 270 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
multi organism reproductive process GO:0044703 262 0.026
response to nutrient levels GO:0031667 370 0.026
defense response GO:0006952 194 0.025
tripeptide transport GO:0042939 2 0.025
lipid transport GO:0006869 61 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
sexual reproduction GO:0019953 148 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
regeneration GO:0031099 163 0.025
associative learning GO:0008306 19 0.025
divalent inorganic cation transport GO:0072511 134 0.025
cell cell signaling GO:0007267 335 0.025
regulation of cell development GO:0060284 263 0.025
protein oligomerization GO:0051259 191 0.025
cognition GO:0050890 92 0.025
negative regulation of signaling GO:0023057 157 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
cellular component biogenesis GO:0044085 368 0.024
intracellular signal transduction GO:0035556 314 0.024
synaptic transmission glutamatergic GO:0035249 33 0.024
amine metabolic process GO:0009308 38 0.023
cardiovascular system development GO:0072358 134 0.023
synaptic transmission GO:0007268 235 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
regulation of apoptotic process GO:0042981 335 0.023
response to oxygen levels GO:0070482 265 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
positive regulation of ion transport GO:0043270 94 0.022
tissue development GO:0009888 252 0.022
response to peptide GO:1901652 292 0.022
regulation of hormone levels GO:0010817 187 0.021
mesoderm development GO:0007498 2 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
secretion GO:0046903 307 0.021
response to nicotine GO:0035094 51 0.020
positive regulation of lipid catabolic process GO:0050996 4 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of protein modification process GO:0031399 194 0.020
negative regulation of cell communication GO:0010648 158 0.020
metal ion transport GO:0030001 289 0.020
skeletal system development GO:0001501 41 0.020
apoptotic process GO:0006915 381 0.020
stress activated protein kinase signaling cascade GO:0031098 37 0.019
growth GO:0040007 165 0.019
metal ion homeostasis GO:0055065 186 0.019
catabolic process GO:0009056 351 0.019
aging GO:0007568 241 0.019
mechanoreceptor differentiation GO:0042490 2 0.019
hair cell differentiation GO:0035315 2 0.019
regulation of glutamate secretion GO:0014048 17 0.019
positive regulation of cell death GO:0010942 184 0.019
adult locomotory behavior GO:0008344 4 0.019
protein phosphorylation GO:0006468 345 0.018
adult behavior GO:0030534 16 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
neuron projection development GO:0031175 273 0.018
ion transmembrane transport GO:0034220 365 0.018
establishment of tissue polarity GO:0007164 2 0.018
regulation of synaptic transmission GO:0050804 141 0.018
activation of protein kinase activity GO:0032147 47 0.018
cellular cation homeostasis GO:0030003 180 0.018
regulation of mapk cascade GO:0043408 116 0.018
regulation of cell differentiation GO:0045595 320 0.018
establishment of planar polarity GO:0001736 1 0.018
multicellular organism growth GO:0035264 1 0.018
hippocampus development GO:0021766 30 0.018
regulation of protein metabolic process GO:0051246 289 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
response to cocaine GO:0042220 39 0.018
cellular response to organonitrogen compound GO:0071417 197 0.017
neuromuscular process GO:0050905 2 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
oxoacid metabolic process GO:0043436 290 0.017
regulation of cell proliferation GO:0042127 359 0.017
cellular response to acid chemical GO:0071229 75 0.017
ras protein signal transduction GO:0007265 29 0.017
positive regulation of developmental process GO:0051094 283 0.017
response to nutrient GO:0007584 248 0.017
cellular component assembly GO:0022607 360 0.017
response to hypoxia GO:0001666 231 0.017
ovulation cycle process GO:0022602 50 0.017
response to toxic substance GO:0009636 133 0.017
hormone secretion GO:0046879 115 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
organic anion transport GO:0015711 132 0.017
regulation of hormone secretion GO:0046883 106 0.017
regulation of secretion GO:0051046 224 0.017
forebrain development GO:0030900 98 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
heart morphogenesis GO:0003007 3 0.016
organ regeneration GO:0031100 101 0.016
single organism behavior GO:0044708 130 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.016
response to metal ion GO:0010038 253 0.016
regulation of establishment of planar polarity GO:0090175 2 0.016
cellular ketone metabolic process GO:0042180 51 0.016
amide transport GO:0042886 105 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
spinal cord development GO:0021510 27 0.016
ossification GO:0001503 70 0.016
response to manganese ion GO:0010042 13 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
negative regulation of amine transport GO:0051953 24 0.016
response to ethanol GO:0045471 162 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
regulation of synaptic transmission glutamatergic GO:0051966 26 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
inorganic anion transport GO:0015698 41 0.015
sensory perception GO:0007600 101 0.015
regulation of amino acid transport GO:0051955 25 0.015
gland development GO:0048732 155 0.015
response to ketone GO:1901654 182 0.015
protein complex assembly GO:0006461 263 0.015
reproduction GO:0000003 245 0.015
regulation of neurogenesis GO:0050767 247 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
serotonin receptor signaling pathway GO:0007210 10 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
response to oxidative stress GO:0006979 186 0.015
macromolecule localization GO:0033036 252 0.014
gonad development GO:0008406 104 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
cellular ion homeostasis GO:0006873 184 0.014
morphogenesis of a polarized epithelium GO:0001738 1 0.014
negative regulation of secretion GO:0051048 82 0.014
locomotion GO:0040011 237 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of anion transport GO:0044070 43 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
single organism catabolic process GO:0044712 283 0.014
insulin secretion GO:0030073 69 0.014
response to alkaloid GO:0043279 132 0.014
neuron development GO:0048666 286 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
positive regulation of cell development GO:0010720 176 0.013
gamete generation GO:0007276 124 0.013
glutathione transport GO:0034635 2 0.013
liver development GO:0001889 90 0.013
positive regulation of kinase activity GO:0033674 77 0.013
response to hexose GO:0009746 144 0.013
embryonic pattern specification GO:0009880 1 0.013
negative regulation of synaptic transmission GO:0050805 29 0.013
regulation of protein kinase activity GO:0045859 105 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of signal transduction GO:0009967 175 0.013
divalent metal ion transport GO:0070838 132 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
protein complex subunit organization GO:0071822 302 0.012
acid secretion GO:0046717 48 0.012
multicellular organismal response to stress GO:0033555 25 0.012
regulation of saliva secretion GO:0046877 3 0.012
response to estrogen GO:0043627 232 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
neuron differentiation GO:0030182 368 0.012
neurotransmitter uptake GO:0001504 3 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
regulation of neuron death GO:1901214 115 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
pallium development GO:0021543 42 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
sex differentiation GO:0007548 113 0.012
axis specification GO:0009798 4 0.012
cellular response to stress GO:0033554 269 0.012
regulation of catalytic activity GO:0050790 304 0.012
amino acid transport GO:0006865 70 0.012
connective tissue development GO:0061448 33 0.012
regulation of cell migration GO:0030334 128 0.012
organophosphate catabolic process GO:0046434 148 0.012
negative regulation of metabolic process GO:0009892 331 0.012
auditory receptor cell differentiation GO:0042491 2 0.012
response to ammonium ion GO:0060359 71 0.011
response to other organism GO:0051707 220 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
response to carbohydrate GO:0009743 183 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of organic acid transport GO:0032890 35 0.011
positive regulation of molecular function GO:0044093 230 0.011
branched chain amino acid transport GO:0015803 2 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
cellular homeostasis GO:0019725 252 0.011
ovulation cycle GO:0042698 67 0.011
response to inorganic substance GO:0010035 377 0.011
regulation of transcription dna templated GO:0006355 374 0.011
circulatory system process GO:0003013 183 0.011
chemical homeostasis GO:0048878 292 0.011
secretion by tissue GO:0032941 37 0.011
glutamate secretion GO:0014047 19 0.011
choline transport GO:0015871 4 0.011
cellular component movement GO:0006928 248 0.011
negative regulation of transport GO:0051051 136 0.011
limbic system development GO:0021761 38 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of locomotion GO:0040012 148 0.011
circadian rhythm GO:0007623 88 0.011
protein complex biogenesis GO:0070271 263 0.011
single organism biosynthetic process GO:0044711 342 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
asymmetric stem cell division GO:0098722 2 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
cellular catabolic process GO:0044248 295 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.010
rna biosynthetic process GO:0032774 380 0.010
antibiotic transport GO:0042891 2 0.010
organophosphate metabolic process GO:0019637 370 0.010
localization of cell GO:0051674 202 0.010
cell motility GO:0048870 202 0.010
regulation of heart rate GO:0002027 16 0.010
purine containing compound metabolic process GO:0072521 253 0.010
female gonad development GO:0008585 53 0.010
response to estradiol GO:0032355 164 0.010
developmental process involved in reproduction GO:0003006 159 0.010
cellular response to magnesium ion GO:0071286 4 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
stem cell division GO:0017145 4 0.010
ion homeostasis GO:0050801 212 0.010

Aifm3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
bone development disease DOID:0080006 0 0.024
bone disease DOID:0080001 0 0.024
musculoskeletal system disease DOID:17 0 0.024
connective tissue disease DOID:65 0 0.024
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
sensory system disease DOID:0050155 0 0.011
disease of metabolism DOID:0014667 0 0.011