Rattus norvegicus

0 known processes

Mitf

microphthalmia-associated transcription factor

Mitf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of apoptotic process GO:0042981 335 0.050
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.036
intracellular signal transduction GO:0035556 314 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
regulation of cellular component organization GO:0051128 368 0.033
programmed cell death GO:0012501 392 0.033
Mouse
neuron differentiation GO:0030182 368 0.032
positive regulation of molecular function GO:0044093 230 0.032
regulation of molecular function GO:0065009 398 0.031
oxoacid metabolic process GO:0043436 290 0.031
single organism biosynthetic process GO:0044711 342 0.031
organic acid metabolic process GO:0006082 292 0.031
organelle organization GO:0006996 266 0.031
organophosphate metabolic process GO:0019637 370 0.031
regulation of programmed cell death GO:0043067 341 0.031
Mouse
regulation of cell differentiation GO:0045595 320 0.030
Mouse
neuron development GO:0048666 286 0.030
cellular component biogenesis GO:0044085 368 0.030
Human
response to extracellular stimulus GO:0009991 380 0.030
nucleotide metabolic process GO:0009117 279 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
Human
apoptotic process GO:0006915 381 0.029
Mouse
response to growth factor GO:0070848 189 0.029
protein phosphorylation GO:0006468 345 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
regulation of rna metabolic process GO:0051252 391 0.028
Human Zebrafish Mouse Rat Worm
regulation of nucleic acid templated transcription GO:1903506 380 0.028
Human Zebrafish Mouse Rat Worm
regulation of intracellular signal transduction GO:1902531 218 0.028
positive regulation of cellular component organization GO:0051130 200 0.028
cellular component assembly GO:0022607 360 0.027
Human
central nervous system development GO:0007417 311 0.027
regulation of signal transduction GO:0009966 318 0.026
regulation of catalytic activity GO:0050790 304 0.026
cell cell signaling GO:0007267 335 0.026
rna biosynthetic process GO:0032774 380 0.025
Human Zebrafish Mouse Rat Worm
positive regulation of biosynthetic process GO:0009891 319 0.025
Human Mouse Worm
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
Human Mouse Worm
regulation of rna biosynthetic process GO:2001141 381 0.025
Human Zebrafish Mouse Rat Worm
regulation of phosphate metabolic process GO:0019220 349 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
cellular component movement GO:0006928 248 0.024
macromolecular complex assembly GO:0065003 273 0.024
Human
rna metabolic process GO:0016070 406 0.024
Human Zebrafish Mouse Rat Worm
organic substance catabolic process GO:1901575 316 0.024
secretion GO:0046903 307 0.023
negative regulation of metabolic process GO:0009892 331 0.023
Human
secretion by cell GO:0032940 248 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
purine containing compound metabolic process GO:0072521 253 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
Mouse
response to nutrient GO:0007584 248 0.022
regulation of cellular component movement GO:0051270 150 0.022
neuron projection development GO:0031175 273 0.022
brain development GO:0007420 247 0.022
protein complex assembly GO:0006461 263 0.022
Human
cellular chemical homeostasis GO:0055082 247 0.022
negative regulation of cell death GO:0060548 229 0.022
Mouse
cell migration GO:0016477 197 0.021
biological adhesion GO:0022610 110 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
Human Mouse Worm
cellular amine metabolic process GO:0044106 38 0.021
regulation of cellular localization GO:0060341 263 0.021
cellular response to lipid GO:0071396 201 0.021
cellular catabolic process GO:0044248 295 0.021
Worm
nucleic acid templated transcription GO:0097659 379 0.021
Human Zebrafish Mouse Rat Worm
positive regulation of developmental process GO:0051094 283 0.021
regulation of nervous system development GO:0051960 264 0.020
cell projection organization GO:0030030 302 0.020
regulation of transcription dna templated GO:0006355 374 0.020
Human Zebrafish Mouse Rat Worm
response to bacterium GO:0009617 200 0.020
Worm
chemical homeostasis GO:0048878 292 0.020
catabolic process GO:0009056 351 0.020
Worm
cellular homeostasis GO:0019725 252 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
response to cytokine GO:0034097 215 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
response to acid chemical GO:0001101 222 0.019
cellular ketone metabolic process GO:0042180 51 0.019
ion homeostasis GO:0050801 212 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
positive regulation of cell development GO:0010720 176 0.019
single organism organelle organization GO:1902589 180 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
eye morphogenesis GO:0048592 4 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
Human Mouse Worm
positive regulation of phosphate metabolic process GO:0045937 262 0.018
response to biotic stimulus GO:0009607 226 0.018
Worm
regulation of phosphorylation GO:0042325 248 0.018
single organism catabolic process GO:0044712 283 0.018
amine metabolic process GO:0009308 38 0.018
response to decreased oxygen levels GO:0036293 237 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
Human Mouse Worm
purine ribonucleotide metabolic process GO:0009150 227 0.018
response to estrogen GO:0043627 232 0.018
proteolysis GO:0006508 175 0.018
anion transport GO:0006820 178 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
Mouse
positive regulation of phosphorylation GO:0042327 177 0.017
regulation of catabolic process GO:0009894 113 0.017
Worm
response to oxygen levels GO:0070482 265 0.017
cation transport GO:0006812 382 0.017
response to inorganic substance GO:0010035 377 0.017
protein complex subunit organization GO:0071822 302 0.017
Human
macromolecule localization GO:0033036 252 0.017
Worm
reproduction GO:0000003 245 0.017
Worm
cellular amino acid metabolic process GO:0006520 107 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
Human Zebrafish Mouse Worm
cellular response to growth factor stimulus GO:0071363 162 0.017
response to nutrient levels GO:0031667 370 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
calcium ion homeostasis GO:0055074 162 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
signal transduction by phosphorylation GO:0023014 144 0.016
cell motility GO:0048870 202 0.016
regulation of hormone levels GO:0010817 187 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
Human Mouse Worm
head development GO:0060322 247 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
Mouse
cellular cation homeostasis GO:0030003 180 0.016
transmembrane transport GO:0055085 412 0.016
regeneration GO:0031099 163 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
ras protein signal transduction GO:0007265 29 0.016
synaptic transmission GO:0007268 235 0.016
signal release GO:0023061 145 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Human
positive regulation of cell communication GO:0010647 271 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
membrane organization GO:0061024 94 0.015
regulation of secretion by cell GO:1903530 208 0.015
positive regulation of nervous system development GO:0051962 178 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
gastrulation GO:0007369 2 0.015
regulation of cell development GO:0060284 263 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
Human
circulatory system process GO:0003013 183 0.015
protein localization GO:0008104 191 0.015
defense response GO:0006952 194 0.015
Worm
localization of cell GO:0051674 202 0.015
reproductive structure development GO:0048608 128 0.015
regulation of neurogenesis GO:0050767 247 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
tissue development GO:0009888 252 0.015
Zebrafish Mouse
positive regulation of signaling GO:0023056 270 0.015
regulation of secretion GO:0051046 224 0.015
neurological system process GO:0050877 219 0.015
regulation of cell proliferation GO:0042127 359 0.015
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.015
response to external biotic stimulus GO:0043207 221 0.015
Worm
cellular response to nitrogen compound GO:1901699 210 0.015
response to carbohydrate GO:0009743 183 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
regulation of neuron differentiation GO:0045664 208 0.015
forebrain development GO:0030900 98 0.015
locomotion GO:0040011 237 0.014
regulation of protein modification process GO:0031399 194 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
negative regulation of transport GO:0051051 136 0.014
carboxylic acid transport GO:0046942 115 0.014
protein complex biogenesis GO:0070271 263 0.014
Human
positive regulation of apoptotic process GO:0043065 154 0.014
growth GO:0040007 165 0.014
reproductive process GO:0022414 372 0.014
vesicle mediated transport GO:0016192 181 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
regulation of system process GO:0044057 208 0.014
nucleoside metabolic process GO:0009116 179 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
Human Mouse Worm
metal ion transport GO:0030001 289 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
response to glucocorticoid GO:0051384 223 0.014
organophosphate catabolic process GO:0046434 148 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
intracellular transport GO:0046907 185 0.014
nitrogen compound transport GO:0071705 229 0.014
metal ion homeostasis GO:0055065 186 0.014
transcription dna templated GO:0006351 377 0.014
Human Zebrafish Mouse Rat Worm
behavior GO:0007610 205 0.014
cellular ion homeostasis GO:0006873 184 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
aromatic compound catabolic process GO:0019439 168 0.014
lipid metabolic process GO:0006629 283 0.014
regulation of cell projection organization GO:0031344 175 0.013
positive regulation of cell migration GO:0030335 96 0.013
aging GO:0007568 241 0.013
Worm
mapk cascade GO:0000165 140 0.013
heterocycle catabolic process GO:0046700 167 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of transport GO:0051050 245 0.013
multicellular organism growth GO:0035264 1 0.013
response to radiation GO:0009314 137 0.013
response to hypoxia GO:0001666 231 0.013
multicellular organism reproduction GO:0032504 233 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to peptide GO:1901652 292 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
reproductive system development GO:0061458 128 0.013
regulation of cell motility GO:2000145 131 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
Human Mouse Worm
positive regulation of cell differentiation GO:0045597 217 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cell projection morphogenesis GO:0048858 123 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
single organism reproductive process GO:0044702 297 0.013
regulation of protein metabolic process GO:0051246 289 0.013
cellular response to stress GO:0033554 269 0.013
response to peptide hormone GO:0043434 278 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
response to metal ion GO:0010038 253 0.013
response to lipopolysaccharide GO:0032496 191 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
taxis GO:0042330 67 0.012
rhythmic process GO:0048511 156 0.012
negative regulation of signaling GO:0023057 157 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
single organism intracellular transport GO:1902582 166 0.012
response to other organism GO:0051707 220 0.012
Worm
response to corticosteroid GO:0031960 235 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
cell adhesion GO:0007155 110 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
Worm
positive regulation of signal transduction GO:0009967 175 0.012
negative regulation of molecular function GO:0044092 133 0.012
camera type eye morphogenesis GO:0048593 2 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
response to vitamin GO:0033273 131 0.012
axis specification GO:0009798 4 0.012
establishment of protein localization GO:0045184 141 0.012
kidney development GO:0001822 67 0.012
nucleotide catabolic process GO:0009166 139 0.012
regulation of locomotion GO:0040012 148 0.012
regulation of cell migration GO:0030334 128 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
negative regulation of cell communication GO:0010648 158 0.012
protein oligomerization GO:0051259 191 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
action potential GO:0001508 54 0.012
positive regulation of protein modification process GO:0031401 142 0.011
circulatory system development GO:0072359 134 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
response to oxidative stress GO:0006979 186 0.011
carbohydrate metabolic process GO:0005975 130 0.011
regulation of anatomical structure size GO:0090066 135 0.011
muscle system process GO:0003012 115 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
purine containing compound catabolic process GO:0072523 138 0.011
telencephalon development GO:0021537 62 0.011
gonad development GO:0008406 104 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
negative regulation of gene expression GO:0010629 199 0.011
Human
positive regulation of mapk cascade GO:0043410 92 0.011
transmission of nerve impulse GO:0019226 42 0.011
rho protein signal transduction GO:0007266 11 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
regulation of neuron projection development GO:0010975 161 0.011
small molecule biosynthetic process GO:0044283 124 0.011
cell growth GO:0016049 104 0.011
regulation of synaptic transmission GO:0050804 141 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
response to wounding GO:0009611 254 0.011
positive regulation of cell death GO:0010942 184 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cation homeostasis GO:0055080 195 0.011
negative regulation of developmental process GO:0051093 125 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
developmental growth GO:0048589 100 0.011
regulation of ion transport GO:0043269 245 0.011
sensory organ development GO:0007423 74 0.011
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
response to toxic substance GO:0009636 133 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
gland development GO:0048732 155 0.011
blood circulation GO:0008015 183 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of blood circulation GO:1903522 110 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
positive regulation of gene expression GO:0010628 244 0.010
Human Mouse Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
Human Mouse Worm
regulation of hydrolase activity GO:0051336 143 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
nucleoside catabolic process GO:0009164 126 0.010
development of primary sexual characteristics GO:0045137 107 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
organic acid transport GO:0015849 116 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
Human

Mitf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.011