Rattus norvegicus

28 known processes

Ermp1

endoplasmic reticulum metallopeptidase 1

(Aliases: Fxna)

Ermp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.097
carboxylic acid metabolic process GO:0019752 289 0.096
oxoacid metabolic process GO:0043436 290 0.067
organic acid metabolic process GO:0006082 292 0.064
negative regulation of cellular metabolic process GO:0031324 281 0.055
lipid metabolic process GO:0006629 283 0.050
response to nutrient levels GO:0031667 370 0.049
catabolic process GO:0009056 351 0.047
organophosphate metabolic process GO:0019637 370 0.046
response to nutrient GO:0007584 248 0.046
response to extracellular stimulus GO:0009991 380 0.046
negative regulation of metabolic process GO:0009892 331 0.043
carbohydrate metabolic process GO:0005975 130 0.041
regulation of protein metabolic process GO:0051246 289 0.040
immune system process GO:0002376 204 0.040
central nervous system development GO:0007417 311 0.040
positive regulation of developmental process GO:0051094 283 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
regulation of cell proliferation GO:0042127 359 0.035
response to growth factor GO:0070848 189 0.035
regulation of ion transport GO:0043269 245 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
organic substance catabolic process GO:1901575 316 0.033
aging GO:0007568 241 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
programmed cell death GO:0012501 392 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
cellular response to oxygen containing compound GO:1901701 386 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
cellular lipid metabolic process GO:0044255 208 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
positive regulation of cell communication GO:0010647 271 0.030
secretion GO:0046903 307 0.030
rna metabolic process GO:0016070 406 0.030
homeostatic process GO:0042592 331 0.029
neurological system process GO:0050877 219 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
single organism carbohydrate metabolic process GO:0044723 118 0.028
amine metabolic process GO:0009308 38 0.028
lipid biosynthetic process GO:0008610 128 0.027
regulation of apoptotic process GO:0042981 335 0.027
alpha amino acid metabolic process GO:1901605 71 0.026
macromolecule localization GO:0033036 252 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
chemical homeostasis GO:0048878 292 0.026
protein phosphorylation GO:0006468 345 0.026
brain development GO:0007420 247 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
monovalent inorganic cation transport GO:0015672 172 0.025
purine containing compound metabolic process GO:0072521 253 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
positive regulation of signaling GO:0023056 270 0.025
positive regulation of transport GO:0051050 245 0.025
developmental process involved in reproduction GO:0003006 159 0.025
synaptic transmission GO:0007268 235 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
regulation of cellular localization GO:0060341 263 0.024
cellular amine metabolic process GO:0044106 38 0.024
cellular response to stress GO:0033554 269 0.024
cellular response to lipid GO:0071396 201 0.023
multicellular organism reproduction GO:0032504 233 0.023
regulation of programmed cell death GO:0043067 341 0.023
apoptotic process GO:0006915 381 0.023
coenzyme metabolic process GO:0006732 86 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
positive regulation of cell proliferation GO:0008284 249 0.022
regulation of rna metabolic process GO:0051252 391 0.022
single organism intracellular transport GO:1902582 166 0.022
cellular protein localization GO:0034613 122 0.022
cellular component assembly GO:0022607 360 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
head development GO:0060322 247 0.022
gland development GO:0048732 155 0.022
development of primary sexual characteristics GO:0045137 107 0.021
cellular ketone metabolic process GO:0042180 51 0.021
anterior posterior pattern specification GO:0009952 1 0.021
regulation of secretion by cell GO:1903530 208 0.021
response to inorganic substance GO:0010035 377 0.021
regulation of hormone levels GO:0010817 187 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
regulation of cellular component organization GO:0051128 368 0.020
single organism catabolic process GO:0044712 283 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
intracellular signal transduction GO:0035556 314 0.020
response to ethanol GO:0045471 162 0.020
nucleic acid templated transcription GO:0097659 379 0.020
cellular catabolic process GO:0044248 295 0.020
regulation of secretion GO:0051046 224 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
reproductive process GO:0022414 372 0.020
response to other organism GO:0051707 220 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
metal ion transport GO:0030001 289 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
proteolysis GO:0006508 175 0.019
ion transmembrane transport GO:0034220 365 0.019
cellular homeostasis GO:0019725 252 0.019
negative regulation of gene expression GO:0010629 199 0.019
neuron differentiation GO:0030182 368 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
response to acid chemical GO:0001101 222 0.019
protein oligomerization GO:0051259 191 0.019
intracellular protein transport GO:0006886 79 0.019
response to oxygen levels GO:0070482 265 0.018
regulation of cell development GO:0060284 263 0.018
gonad development GO:0008406 104 0.018
sex differentiation GO:0007548 113 0.018
cell cell signaling GO:0007267 335 0.018
response to decreased oxygen levels GO:0036293 237 0.018
regulation of cell differentiation GO:0045595 320 0.018
regulation of molecular function GO:0065009 398 0.018
reproductive system development GO:0061458 128 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
multi organism reproductive process GO:0044703 262 0.018
positive regulation of nervous system development GO:0051962 178 0.017
developmental growth GO:0048589 100 0.017
protein complex biogenesis GO:0070271 263 0.017
cation homeostasis GO:0055080 195 0.017
response to hypoxia GO:0001666 231 0.017
response to peptide GO:1901652 292 0.017
regulation of transcription dna templated GO:0006355 374 0.017
rna biosynthetic process GO:0032774 380 0.017
cation transport GO:0006812 382 0.017
macromolecule catabolic process GO:0009057 58 0.017
intracellular transport GO:0046907 185 0.017
regulation of system process GO:0044057 208 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
sodium ion transport GO:0006814 82 0.017
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of cell development GO:0010720 176 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
growth GO:0040007 165 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular component biogenesis GO:0044085 368 0.016
response to biotic stimulus GO:0009607 226 0.016
positive regulation of signal transduction GO:0009967 175 0.016
secretion by cell GO:0032940 248 0.016
protein heterooligomerization GO:0051291 89 0.016
glycerolipid metabolic process GO:0046486 67 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regeneration GO:0031099 163 0.016
cellular macromolecule localization GO:0070727 122 0.016
organophosphate biosynthetic process GO:0090407 143 0.015
defense response GO:0006952 194 0.015
regulation of metal ion transport GO:0010959 118 0.015
regulation of catabolic process GO:0009894 113 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
protein complex subunit organization GO:0071822 302 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
action potential GO:0001508 54 0.015
circulatory system process GO:0003013 183 0.015
positive regulation of molecular function GO:0044093 230 0.015
nitrogen compound transport GO:0071705 229 0.015
eye morphogenesis GO:0048592 4 0.015
positive regulation of ion transport GO:0043270 94 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
calcium ion homeostasis GO:0055074 162 0.015
transcription dna templated GO:0006351 377 0.015
glycosyl compound metabolic process GO:1901657 182 0.014
transmembrane transport GO:0055085 412 0.014
regulation of nervous system development GO:0051960 264 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
ion homeostasis GO:0050801 212 0.014
tissue development GO:0009888 252 0.014
single organism reproductive process GO:0044702 297 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
cellular component movement GO:0006928 248 0.014
establishment of protein localization GO:0045184 141 0.014
fatty acid metabolic process GO:0006631 99 0.014
response to ketone GO:1901654 182 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
reproduction GO:0000003 245 0.014
phospholipid metabolic process GO:0006644 61 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
signal release GO:0023061 145 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
response to estrogen GO:0043627 232 0.013
negative regulation of signaling GO:0023057 157 0.013
response to bacterium GO:0009617 200 0.013
neuron projection development GO:0031175 273 0.013
protein transport GO:0015031 132 0.013
regulation of catalytic activity GO:0050790 304 0.013
regulation of phosphorylation GO:0042325 248 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
organelle organization GO:0006996 266 0.013
heart morphogenesis GO:0003007 3 0.013
organ morphogenesis GO:0009887 75 0.013
regulation of signal transduction GO:0009966 318 0.013
response to peptide hormone GO:0043434 278 0.013
negative regulation of rna metabolic process GO:0051253 123 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
blood circulation GO:0008015 183 0.012
organic acid transport GO:0015849 116 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
cell type specific apoptotic process GO:0097285 134 0.012
protein localization GO:0008104 191 0.012
macromolecular complex assembly GO:0065003 273 0.012
negative regulation of transport GO:0051051 136 0.012
nucleotide metabolic process GO:0009117 279 0.012
response to carbohydrate GO:0009743 183 0.012
protein complex assembly GO:0006461 263 0.012
neuron development GO:0048666 286 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
positive regulation of cell death GO:0010942 184 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
negative regulation of cell death GO:0060548 229 0.012
neuron death GO:0070997 127 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of catabolic process GO:0009896 78 0.011
cell cycle checkpoint GO:0000075 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
response to corticosteroid GO:0031960 235 0.011
oxidation reduction process GO:0055114 304 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of membrane potential GO:0042391 110 0.011
small molecule biosynthetic process GO:0044283 124 0.011
muscle system process GO:0003012 115 0.011
positive regulation of gene expression GO:0010628 244 0.011
behavior GO:0007610 205 0.011
dephosphorylation GO:0016311 98 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
hormone secretion GO:0046879 115 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
reproductive structure development GO:0048608 128 0.011
ras protein signal transduction GO:0007265 29 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
response to metal ion GO:0010038 253 0.011
potassium ion transport GO:0006813 97 0.011
cellular ion homeostasis GO:0006873 184 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
response to oxidative stress GO:0006979 186 0.011
dna metabolic process GO:0006259 96 0.011
sulfur compound metabolic process GO:0006790 70 0.011
axis specification GO:0009798 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
regulation of transmembrane transport GO:0034762 122 0.011
cellular amide metabolic process GO:0043603 44 0.011
cofactor metabolic process GO:0051186 95 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
female gonad development GO:0008585 53 0.011
cell growth GO:0016049 104 0.011
organ regeneration GO:0031100 101 0.010
purine containing compound catabolic process GO:0072523 138 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
small molecule catabolic process GO:0044282 59 0.010
cell projection organization GO:0030030 302 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
response to external biotic stimulus GO:0043207 221 0.010
urogenital system development GO:0001655 78 0.010
multi multicellular organism process GO:0044706 138 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
localization of cell GO:0051674 202 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
response to hexose GO:0009746 144 0.010

Ermp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.013
central nervous system disease DOID:331 0 0.010
sensory system disease DOID:0050155 0 0.010