Rattus norvegicus

25 known processes

Vapa

VAMP (vesicle-associated membrane protein)-associated protein A

Vapa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.217
Yeast
transcription dna templated GO:0006351 377 0.173
Yeast
carbohydrate metabolic process GO:0005975 130 0.161
regulation of rna metabolic process GO:0051252 391 0.160
Yeast
regulation of proteasomal protein catabolic process GO:0061136 4 0.144
cellular catabolic process GO:0044248 295 0.141
regulation of protein metabolic process GO:0051246 289 0.130
cellular lipid metabolic process GO:0044255 208 0.123
Yeast
cellular response to stress GO:0033554 269 0.116
carboxylic acid metabolic process GO:0019752 289 0.116
regulation of signal transduction GO:0009966 318 0.100
response to biotic stimulus GO:0009607 226 0.097
response to external biotic stimulus GO:0043207 221 0.093
regulation of transcription dna templated GO:0006355 374 0.088
Yeast
negative regulation of response to stimulus GO:0048585 155 0.085
response to other organism GO:0051707 220 0.084
enzyme linked receptor protein signaling pathway GO:0007167 116 0.083
homeostatic process GO:0042592 331 0.082
negative regulation of metabolic process GO:0009892 331 0.077
Yeast
glycogen metabolic process GO:0005977 23 0.076
transcription from rna polymerase ii promoter GO:0006366 252 0.074
negative regulation of gene expression GO:0010629 199 0.072
Yeast
regulation of rna biosynthetic process GO:2001141 381 0.067
Yeast
negative regulation of transport GO:0051051 136 0.065
Yeast
rna biosynthetic process GO:0032774 380 0.065
Yeast
oxidation reduction process GO:0055114 304 0.064
locomotion GO:0040011 237 0.064
positive regulation of response to stimulus GO:0048584 285 0.061
organic acid metabolic process GO:0006082 292 0.060
positive regulation of signaling GO:0023056 270 0.059
response to bacterium GO:0009617 200 0.059
catabolic process GO:0009056 351 0.058
protein dephosphorylation GO:0006470 38 0.056
programmed cell death GO:0012501 392 0.055
protein complex subunit organization GO:0071822 302 0.055
rna metabolic process GO:0016070 406 0.055
Yeast
regulation of cell migration GO:0030334 128 0.055
glucan metabolic process GO:0044042 23 0.054
proteolysis GO:0006508 175 0.053
positive regulation of signal transduction GO:0009967 175 0.052
negative regulation of rna metabolic process GO:0051253 123 0.052
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.052
oxoacid metabolic process GO:0043436 290 0.051
macromolecule catabolic process GO:0009057 58 0.051
lipid metabolic process GO:0006629 283 0.050
Yeast
cellular component biogenesis GO:0044085 368 0.050
monocarboxylic acid metabolic process GO:0032787 152 0.047
intracellular transport GO:0046907 185 0.047
Yeast
defense response GO:0006952 194 0.046
dephosphorylation GO:0016311 98 0.046
Yeast
negative regulation of cellular metabolic process GO:0031324 281 0.045
Yeast
regulation of cellular component organization GO:0051128 368 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
Yeast
intracellular signal transduction GO:0035556 314 0.044
negative regulation of protein metabolic process GO:0051248 114 0.042
negative regulation of signaling GO:0023057 157 0.041
negative regulation of biosynthetic process GO:0009890 168 0.041
Yeast
positive regulation of cell communication GO:0010647 271 0.041
protein catabolic process GO:0030163 30 0.040
regulation of apoptotic process GO:0042981 335 0.040
macromolecular complex assembly GO:0065003 273 0.039
regulation of cell differentiation GO:0045595 320 0.039
regulation of nucleic acid templated transcription GO:1903506 380 0.039
Yeast
fatty acid metabolic process GO:0006631 99 0.038
negative regulation of signal transduction GO:0009968 83 0.038
cell morphogenesis involved in differentiation GO:0000904 119 0.037
regulation of protein modification process GO:0031399 194 0.037
chemical homeostasis GO:0048878 292 0.036
regulation of protein transport GO:0051223 68 0.036
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
Yeast
protein modification by small protein conjugation GO:0032446 31 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.034
regulation of cellular localization GO:0060341 263 0.034
Yeast
regulation of multicellular organismal development GO:2000026 376 0.034
regulation of programmed cell death GO:0043067 341 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
response to inorganic substance GO:0010035 377 0.031
organic substance catabolic process GO:1901575 316 0.031
neuron development GO:0048666 286 0.031
localization of cell GO:0051674 202 0.031
single organism carbohydrate metabolic process GO:0044723 118 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
cellular protein catabolic process GO:0044257 19 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
regulation of cellular component movement GO:0051270 150 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
Yeast
regulation of protein catabolic process GO:0042176 16 0.030
cellular component assembly GO:0022607 360 0.030
cellular carbohydrate metabolic process GO:0044262 72 0.029
cellular homeostasis GO:0019725 252 0.029
regulation of transporter activity GO:0032409 50 0.029
vesicle mediated transport GO:0016192 181 0.029
regulation of cell proliferation GO:0042127 359 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
immune system process GO:0002376 204 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
Yeast
cellular amino acid metabolic process GO:0006520 107 0.027
cation transport GO:0006812 382 0.027
regulation of cell motility GO:2000145 131 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
protein modification by small protein conjugation or removal GO:0070647 35 0.027
single organism catabolic process GO:0044712 283 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.026
positive regulation of protein metabolic process GO:0051247 178 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.026
apoptotic process GO:0006915 381 0.026
regulation of locomotion GO:0040012 148 0.025
cellular response to hormone stimulus GO:0032870 247 0.025
cell motility GO:0048870 202 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
ion homeostasis GO:0050801 212 0.025
regulation of nucleocytoplasmic transport GO:0046822 28 0.024
Yeast
single organism organelle organization GO:1902589 180 0.024
Yeast
cell morphogenesis GO:0000902 142 0.024
monocarboxylic acid biosynthetic process GO:0072330 48 0.024
nitrogen compound transport GO:0071705 229 0.024
cytoplasmic transport GO:0016482 115 0.024
Yeast
positive regulation of phosphorylation GO:0042327 177 0.024
cardiac ventricle development GO:0003231 1 0.024
ion transmembrane transport GO:0034220 365 0.024
response to metal ion GO:0010038 253 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
chromosome segregation GO:0007059 2 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
response to growth factor GO:0070848 189 0.023
cation homeostasis GO:0055080 195 0.023
carboxylic acid biosynthetic process GO:0046394 83 0.023
ubiquitin dependent protein catabolic process GO:0006511 14 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
Yeast
protein complex assembly GO:0006461 263 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
organophosphate metabolic process GO:0019637 370 0.022
Yeast
protein complex biogenesis GO:0070271 263 0.022
regulation of response to stress GO:0080134 126 0.022
metal ion transport GO:0030001 289 0.022
multicellular organism reproduction GO:0032504 233 0.022
response to extracellular stimulus GO:0009991 380 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
generation of precursor metabolites and energy GO:0006091 62 0.022
negative regulation of cell death GO:0060548 229 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
protein ubiquitination GO:0016567 28 0.022
calcium ion transmembrane transport GO:0070588 70 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
cellular ion homeostasis GO:0006873 184 0.022
cytokine production GO:0001816 61 0.021
regulation of phosphorylation GO:0042325 248 0.021
dna metabolic process GO:0006259 96 0.021
negative regulation of phosphorylation GO:0042326 57 0.021
purine containing compound metabolic process GO:0072521 253 0.021
monosaccharide metabolic process GO:0005996 61 0.021
divalent metal ion transport GO:0070838 132 0.021
negative regulation of cell communication GO:0010648 158 0.021
reproductive process GO:0022414 372 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
Yeast
organic acid biosynthetic process GO:0016053 83 0.020
cellular protein localization GO:0034613 122 0.020
Yeast
regulation of molecular function GO:0065009 398 0.020
energy derivation by oxidation of organic compounds GO:0015980 46 0.020
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
divalent inorganic cation transport GO:0072511 134 0.020
regulation of metal ion transport GO:0010959 118 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
ras protein signal transduction GO:0007265 29 0.019
multi organism reproductive process GO:0044703 262 0.019
transmembrane transport GO:0055085 412 0.019
positive regulation of molecular function GO:0044093 230 0.019
unsaturated fatty acid metabolic process GO:0033559 39 0.019
cellular component movement GO:0006928 248 0.019
single organism intracellular transport GO:1902582 166 0.019
Yeast
negative regulation of transcription dna templated GO:0045892 116 0.019
Yeast
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of developmental process GO:0051094 283 0.019
single organism reproductive process GO:0044702 297 0.019
fatty acid derivative metabolic process GO:1901568 38 0.018
cell projection morphogenesis GO:0048858 123 0.018
cardiac chamber development GO:0003205 1 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.018
regulation of hormone levels GO:0010817 187 0.018
calcium ion transport GO:0006816 131 0.018
intracellular receptor signaling pathway GO:0030522 35 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
immune response GO:0006955 104 0.018
neuron projection morphogenesis GO:0048812 122 0.018
lipid biosynthetic process GO:0008610 128 0.018
Yeast
cellular amine metabolic process GO:0044106 38 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
dna replication GO:0006260 37 0.018
regulation of nervous system development GO:0051960 264 0.018
response to peptide GO:1901652 292 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
regulation of cell development GO:0060284 263 0.017
nucleoside metabolic process GO:0009116 179 0.017
small molecule biosynthetic process GO:0044283 124 0.017
rhythmic process GO:0048511 156 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
response to heat GO:0009408 60 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
cellular chemical homeostasis GO:0055082 247 0.017
single organism biosynthetic process GO:0044711 342 0.017
Yeast
cellular macromolecule catabolic process GO:0044265 29 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
Yeast
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
response to cytokine GO:0034097 215 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
Yeast
cell cycle checkpoint GO:0000075 2 0.016
polysaccharide metabolic process GO:0005976 25 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
neuron projection development GO:0031175 273 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
regulation of proteolysis GO:0030162 66 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
heart development GO:0007507 72 0.016
modification dependent macromolecule catabolic process GO:0043632 14 0.016
regulation of smoothened signaling pathway GO:0008589 2 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
negative regulation of transporter activity GO:0032410 13 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
Yeast
positive regulation of biosynthetic process GO:0009891 319 0.016
actin filament based process GO:0030029 86 0.016
cell migration GO:0016477 197 0.015
response to transforming growth factor beta GO:0071559 46 0.015
multi multicellular organism process GO:0044706 138 0.015
amine metabolic process GO:0009308 38 0.015
salivary gland development GO:0007431 3 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
endocytosis GO:0006897 84 0.015
response to glucocorticoid GO:0051384 223 0.015
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.015
negative regulation of cell development GO:0010721 82 0.015
cellular response to alcohol GO:0097306 87 0.015
positive regulation of cell death GO:0010942 184 0.015
cell cycle GO:0007049 101 0.015
cation transmembrane transport GO:0098655 263 0.015
regulation of cell morphogenesis GO:0022604 77 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
blood circulation GO:0008015 183 0.014
protein heterooligomerization GO:0051291 89 0.014
regulation of ion transport GO:0043269 245 0.014
aromatic compound catabolic process GO:0019439 168 0.014
regulation of sister chromatid segregation GO:0033045 1 0.014
positive regulation of gene expression GO:0010628 244 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
response to nutrient levels GO:0031667 370 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
Yeast
negative regulation of apoptotic process GO:0043066 181 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
reproduction GO:0000003 245 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
negative regulation of protein phosphorylation GO:0001933 44 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
metaphase anaphase transition of cell cycle GO:0044784 1 0.014
metal ion homeostasis GO:0055065 186 0.014
spindle organization GO:0007051 2 0.014
cell part morphogenesis GO:0032990 123 0.014
regulation of epithelial to mesenchymal transition GO:0010717 2 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
protein phosphorylation GO:0006468 345 0.014
mitotic sister chromatid separation GO:0051306 1 0.014
cell projection organization GO:0030030 302 0.014
embryonic pattern specification GO:0009880 1 0.014
regulation of neurogenesis GO:0050767 247 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
regulation of stem cell differentiation GO:2000736 2 0.014
dna integrity checkpoint GO:0031570 2 0.013
cell cell signaling GO:0007267 335 0.013
cellular component morphogenesis GO:0032989 155 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
cell cycle process GO:0022402 57 0.013
cellular polysaccharide metabolic process GO:0044264 23 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
negative regulation of developmental process GO:0051093 125 0.013
adult locomotory behavior GO:0008344 4 0.013
regulation of intracellular transport GO:0032386 65 0.013
Yeast
signal transduction by phosphorylation GO:0023014 144 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
response to reactive oxygen species GO:0000302 120 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
negative regulation of molecular function GO:0044092 133 0.013
neuron differentiation GO:0030182 368 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.013
regulation of protein phosphatase type 2a activity GO:0034047 2 0.013
regulation of immune system process GO:0002682 123 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
cellular response to external stimulus GO:0071496 118 0.013
glycogen biosynthetic process GO:0005978 15 0.013
regulation of protein import into nucleus GO:0042306 24 0.013
Yeast
positive regulation of protein dephosphorylation GO:0035307 4 0.013
positive regulation of phosphoprotein phosphatase activity GO:0032516 3 0.012
chemosensory behavior GO:0007635 2 0.012
regulation of mitotic sister chromatid segregation GO:0033047 1 0.012
energy reserve metabolic process GO:0006112 25 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of defense response GO:0031347 68 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.012
hormone secretion GO:0046879 115 0.012
negative regulation of ion transport GO:0043271 51 0.012
peptide hormone secretion GO:0030072 84 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of catalytic activity GO:0050790 304 0.012
regulation of mitotic sister chromatid separation GO:0010965 1 0.012
negative regulation of innate immune response GO:0045824 4 0.012
salivary gland morphogenesis GO:0007435 1 0.012
cellular cation homeostasis GO:0030003 180 0.012
response to temperature stimulus GO:0009266 94 0.012
anterior posterior pattern specification GO:0009952 1 0.012
neurological system process GO:0050877 219 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
cellular ketone metabolic process GO:0042180 51 0.012
positive regulation of cell migration GO:0030335 96 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
gastrulation GO:0007369 2 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of neuron differentiation GO:0045664 208 0.011
macromolecule localization GO:0033036 252 0.011
Yeast
peptide transport GO:0015833 97 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
tissue development GO:0009888 252 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
chromosome separation GO:0051304 1 0.011
biological adhesion GO:0022610 110 0.011
maintenance of location GO:0051235 17 0.011
developmental process involved in reproduction GO:0003006 159 0.011
carbohydrate homeostasis GO:0033500 75 0.011
positive regulation of cell development GO:0010720 176 0.011
response to radiation GO:0009314 137 0.011
circulatory system process GO:0003013 183 0.011
positive regulation of secretion GO:0051047 140 0.011
sister chromatid segregation GO:0000819 1 0.011
single organism cellular localization GO:1902580 102 0.011
Yeast
regulation of catabolic process GO:0009894 113 0.011
response to peptide hormone GO:0043434 278 0.011
metaphase plate congression GO:0051310 1 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
response to toxic substance GO:0009636 133 0.011
regulation of cytokine production GO:0001817 56 0.011
stem cell division GO:0017145 4 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
lipid storage GO:0019915 1 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
cellular response to lipid GO:0071396 201 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
Yeast
positive regulation of protein kinase activity GO:0045860 73 0.010
tube development GO:0035295 89 0.010
centrosome cycle GO:0007098 1 0.010
gamete generation GO:0007276 124 0.010
neuronal stem cell division GO:0036445 1 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
female pregnancy GO:0007565 122 0.010

Vapa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org