Rattus norvegicus

0 known processes

Sfxn1

sideroflexin 1

Sfxn1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.254
organic acid biosynthetic process GO:0016053 83 0.222
carboxylic acid metabolic process GO:0019752 289 0.193
single organism biosynthetic process GO:0044711 342 0.145
organic acid metabolic process GO:0006082 292 0.116
organonitrogen compound biosynthetic process GO:1901566 167 0.108
cellular amino acid biosynthetic process GO:0008652 32 0.104
alpha amino acid metabolic process GO:1901605 71 0.102
response to nutrient GO:0007584 248 0.095
response to nutrient levels GO:0031667 370 0.087
response to extracellular stimulus GO:0009991 380 0.078
small molecule catabolic process GO:0044282 59 0.076
cellular modified amino acid metabolic process GO:0006575 61 0.075
cellular amino acid metabolic process GO:0006520 107 0.072
alpha amino acid biosynthetic process GO:1901607 23 0.071
organic substance catabolic process GO:1901575 316 0.071
neuron differentiation GO:0030182 368 0.068
carboxylic acid biosynthetic process GO:0046394 83 0.059
small molecule biosynthetic process GO:0044283 124 0.052
carboxylic acid catabolic process GO:0046395 49 0.050
single organism catabolic process GO:0044712 283 0.048
catabolic process GO:0009056 351 0.048
cellular component biogenesis GO:0044085 368 0.047
neuron projection development GO:0031175 273 0.046
response to oxygen levels GO:0070482 265 0.046
cellular catabolic process GO:0044248 295 0.046
cellular response to endogenous stimulus GO:0071495 377 0.045
transmembrane transport GO:0055085 412 0.045
cell projection organization GO:0030030 302 0.043
sulfur compound biosynthetic process GO:0044272 19 0.043
brain development GO:0007420 247 0.043
ion transmembrane transport GO:0034220 365 0.041
protein phosphorylation GO:0006468 345 0.040
central nervous system development GO:0007417 311 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.039
rhythmic process GO:0048511 156 0.037
cellular amino acid catabolic process GO:0009063 21 0.037
regulation of phosphate metabolic process GO:0019220 349 0.037
regulation of signal transduction GO:0009966 318 0.036
defense response GO:0006952 194 0.036
sulfur amino acid metabolic process GO:0000096 9 0.035
positive regulation of developmental process GO:0051094 283 0.034
anion transport GO:0006820 178 0.034
protein complex biogenesis GO:0070271 263 0.034
carboxylic acid transport GO:0046942 115 0.034
protein complex subunit organization GO:0071822 302 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
regulation of cellular component organization GO:0051128 368 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.033
macromolecular complex assembly GO:0065003 273 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
lipid metabolic process GO:0006629 283 0.032
organic acid catabolic process GO:0016054 49 0.032
regulation of protein metabolic process GO:0051246 289 0.032
positive regulation of signaling GO:0023056 270 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
neurological system process GO:0050877 219 0.031
intracellular signal transduction GO:0035556 314 0.031
head development GO:0060322 247 0.031
response to inorganic substance GO:0010035 377 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.030
response to other organism GO:0051707 220 0.030
behavior GO:0007610 205 0.030
response to hypoxia GO:0001666 231 0.029
regulation of phosphorylation GO:0042325 248 0.029
inflammatory response GO:0006954 150 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
response to glucocorticoid GO:0051384 223 0.029
regulation of molecular function GO:0065009 398 0.028
cellular component movement GO:0006928 248 0.028
organic anion transport GO:0015711 132 0.028
sulfur amino acid biosynthetic process GO:0000097 5 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
regulation of catalytic activity GO:0050790 304 0.028
response to estrogen GO:0043627 232 0.028
multicellular organism reproduction GO:0032504 233 0.027
apoptotic process GO:0006915 381 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
negative regulation of metabolic process GO:0009892 331 0.027
cellular component assembly GO:0022607 360 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
neuron development GO:0048666 286 0.027
metal ion transport GO:0030001 289 0.027
Mouse
regulation of apoptotic process GO:0042981 335 0.027
homeostatic process GO:0042592 331 0.027
Mouse
cellular amide metabolic process GO:0043603 44 0.027
reproductive process GO:0022414 372 0.027
locomotion GO:0040011 237 0.026
organic acid transport GO:0015849 116 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
cellular homeostasis GO:0019725 252 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
cellular response to stress GO:0033554 269 0.026
monocarboxylic acid metabolic process GO:0032787 152 0.026
alpha amino acid catabolic process GO:1901606 20 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
organophosphate biosynthetic process GO:0090407 143 0.024
intracellular transport GO:0046907 185 0.024
cell motility GO:0048870 202 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
positive regulation of biosynthetic process GO:0009891 319 0.023
regulation of ion transport GO:0043269 245 0.023
regulation of transcription dna templated GO:0006355 374 0.023
positive regulation of molecular function GO:0044093 230 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
secretion GO:0046903 307 0.023
lipid biosynthetic process GO:0008610 128 0.023
purine containing compound metabolic process GO:0072521 253 0.023
reproduction GO:0000003 245 0.023
response to bacterium GO:0009617 200 0.022
reproductive structure development GO:0048608 128 0.022
positive regulation of transport GO:0051050 245 0.022
programmed cell death GO:0012501 392 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
protein complex assembly GO:0006461 263 0.021
cellular amine metabolic process GO:0044106 38 0.021
regulation of cell development GO:0060284 263 0.021
cellular modified amino acid catabolic process GO:0042219 1 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
response to toxic substance GO:0009636 133 0.021
cell migration GO:0016477 197 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
positive regulation of protein modification process GO:0031401 142 0.021
rna metabolic process GO:0016070 406 0.020
gonad development GO:0008406 104 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
cation transmembrane transport GO:0098655 263 0.020
positive regulation of cell communication GO:0010647 271 0.020
rna biosynthetic process GO:0032774 380 0.020
regulation of rna metabolic process GO:0051252 391 0.020
amine metabolic process GO:0009308 38 0.020
organophosphate metabolic process GO:0019637 370 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
response to cytokine GO:0034097 215 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
cell morphogenesis GO:0000902 142 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
regulation of protein modification process GO:0031399 194 0.020
transcription dna templated GO:0006351 377 0.019
cellular cation homeostasis GO:0030003 180 0.019
synaptic transmission GO:0007268 235 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
negative regulation of cell communication GO:0010648 158 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
response to corticosteroid GO:0031960 235 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
response to carbohydrate GO:0009743 183 0.019
regulation of catabolic process GO:0009894 113 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
nucleoside phosphate biosynthetic process GO:1901293 102 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
response to vitamin GO:0033273 131 0.019
cellular ketone metabolic process GO:0042180 51 0.019
localization of cell GO:0051674 202 0.019
response to external biotic stimulus GO:0043207 221 0.019
response to metal ion GO:0010038 253 0.018
neuron projection morphogenesis GO:0048812 122 0.018
ion homeostasis GO:0050801 212 0.018
regulation of nervous system development GO:0051960 264 0.018
sulfur compound metabolic process GO:0006790 70 0.018
response to decreased oxygen levels GO:0036293 237 0.018
regulation of cell differentiation GO:0045595 320 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of kinase activity GO:0043549 117 0.018
biological adhesion GO:0022610 110 0.018
growth GO:0040007 165 0.018
cell growth GO:0016049 104 0.018
response to mechanical stimulus GO:0009612 134 0.018
nucleotide biosynthetic process GO:0009165 98 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
response to peptide hormone GO:0043434 278 0.018
regulation of transferase activity GO:0051338 123 0.018
negative regulation of gene expression GO:0010629 199 0.018
monocarboxylic acid biosynthetic process GO:0072330 48 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
tissue development GO:0009888 252 0.017
aging GO:0007568 241 0.017
response to glucose GO:0009749 136 0.017
cell cell signaling GO:0007267 335 0.017
immune response GO:0006955 104 0.017
cellular response to lipid GO:0071396 201 0.017
cognition GO:0050890 92 0.017
nucleoside metabolic process GO:0009116 179 0.017
nitrogen compound transport GO:0071705 229 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regulation of secretion GO:0051046 224 0.017
cell projection morphogenesis GO:0048858 123 0.017
protein localization GO:0008104 191 0.016
sex differentiation GO:0007548 113 0.016
taxis GO:0042330 67 0.016
response to acid chemical GO:0001101 222 0.016
synaptic vesicle endocytosis GO:0048488 4 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
aromatic compound catabolic process GO:0019439 168 0.016
response to ketone GO:1901654 182 0.016
reproductive system development GO:0061458 128 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
regulation of membrane potential GO:0042391 110 0.016
circadian rhythm GO:0007623 88 0.016
regulation of programmed cell death GO:0043067 341 0.016
response to hexose GO:0009746 144 0.016
cation transport GO:0006812 382 0.016
Mouse
response to lipopolysaccharide GO:0032496 191 0.016
positive regulation of signal transduction GO:0009967 175 0.016
response to peptide GO:1901652 292 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
nucleotide metabolic process GO:0009117 279 0.015
response to biotic stimulus GO:0009607 226 0.015
axonogenesis GO:0007409 71 0.015
homocysteine metabolic process GO:0050667 6 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
development of primary sexual characteristics GO:0045137 107 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to growth factor GO:0070848 189 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of neuron projection development GO:0010975 161 0.015
developmental process involved in reproduction GO:0003006 159 0.015
immune system process GO:0002376 204 0.015
Mouse
cellular chemical homeostasis GO:0055082 247 0.015
long chain fatty acid metabolic process GO:0001676 32 0.015
regulation of hormone levels GO:0010817 187 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
macromolecule catabolic process GO:0009057 58 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
kidney development GO:0001822 67 0.014
macromolecule localization GO:0033036 252 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
cellular response to peptide GO:1901653 133 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
protein oligomerization GO:0051259 191 0.014
cell adhesion GO:0007155 110 0.014
anion transmembrane transport GO:0098656 77 0.014
positive regulation of cell development GO:0010720 176 0.014
steroid metabolic process GO:0008202 73 0.014
ribose phosphate metabolic process GO:0019693 235 0.013
regulation of anatomical structure size GO:0090066 135 0.013
fatty acid metabolic process GO:0006631 99 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of system process GO:0044057 208 0.013
endocytosis GO:0006897 84 0.013
regulation of cell proliferation GO:0042127 359 0.013
multi organism reproductive process GO:0044703 262 0.013
blood vessel development GO:0001568 69 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
multicellular organism growth GO:0035264 1 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
cellular modified amino acid biosynthetic process GO:0042398 18 0.013
response to monosaccharide GO:0034284 159 0.013
blood circulation GO:0008015 183 0.013
cytoplasmic transport GO:0016482 115 0.013
cellular component morphogenesis GO:0032989 155 0.013
negative regulation of cell death GO:0060548 229 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
regulation of cellular component movement GO:0051270 150 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
amino acid transport GO:0006865 70 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
oxidation reduction process GO:0055114 304 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
response to oxidative stress GO:0006979 186 0.013
metal ion homeostasis GO:0055065 186 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
response to herbicide GO:0009635 16 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
vesicle mediated transport GO:0016192 181 0.012
nucleic acid templated transcription GO:0097659 379 0.012
positive regulation of cell death GO:0010942 184 0.012
response to wounding GO:0009611 254 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
regulation of cell cycle GO:0051726 73 0.012
negative regulation of signaling GO:0023057 157 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of neurogenesis GO:0050767 247 0.012
response to alkaloid GO:0043279 132 0.012
chromosome segregation GO:0007059 2 0.012
cell substrate adhesion GO:0031589 29 0.012
cellular ion homeostasis GO:0006873 184 0.012
eye morphogenesis GO:0048592 4 0.012
response to radiation GO:0009314 137 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
single organism reproductive process GO:0044702 297 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
response to organophosphorus GO:0046683 102 0.012
regulation of cell adhesion GO:0030155 52 0.012
response to fatty acid GO:0070542 65 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
peptide metabolic process GO:0006518 32 0.011
regulation of cellular localization GO:0060341 263 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
developmental growth GO:0048589 100 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
learning or memory GO:0007611 90 0.011
positive regulation of gene expression GO:0010628 244 0.011
regulation of cell motility GO:2000145 131 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
cellular lipid metabolic process GO:0044255 208 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of secretion by cell GO:1903530 208 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of gtpase activity GO:0043087 57 0.011
carbohydrate metabolic process GO:0005975 130 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
bmp signaling pathway GO:0030509 4 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
lipid transport GO:0006869 61 0.011
establishment of protein localization GO:0045184 141 0.011
adult locomotory behavior GO:0008344 4 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to ethanol GO:0045471 162 0.011
cellular response to external stimulus GO:0071496 118 0.011
regulation of neuron differentiation GO:0045664 208 0.011
cation homeostasis GO:0055080 195 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
single organism behavior GO:0044708 130 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
axon development GO:0061564 96 0.010
regulation of growth GO:0040008 105 0.010
sexual reproduction GO:0019953 148 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
axis specification GO:0009798 4 0.010
response to amine GO:0014075 46 0.010
regulation of locomotion GO:0040012 148 0.010
membrane organization GO:0061024 94 0.010
tube development GO:0035295 89 0.010
dephosphorylation GO:0016311 98 0.010

Sfxn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
amino acid metabolic disorder DOID:9252 0 0.023
sensory system disease DOID:0050155 0 0.012
central nervous system disease DOID:331 0 0.011