Rattus norvegicus

222 known processes

Rap1a

RAP1A, member of RAS oncogene family

(Aliases: rap 1A,MGC94873,MGC93785,RAP-1A)

Rap1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 181 0.264
Mouse
regulation of rna metabolic process GO:0051252 391 0.153
rna biosynthetic process GO:0032774 380 0.136
protein phosphorylation GO:0006468 345 0.102
protein localization GO:0008104 191 0.090
Human
transcription dna templated GO:0006351 377 0.083
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.080
positive regulation of transcription dna templated GO:0045893 197 0.077
regulation of nucleic acid templated transcription GO:1903506 380 0.076
macromolecule localization GO:0033036 252 0.075
Human
nucleic acid templated transcription GO:0097659 379 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.068
regulation of rna biosynthetic process GO:2001141 381 0.067
regulation of cellular localization GO:0060341 263 0.066
Mouse
secretion GO:0046903 307 0.064
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.061
positive regulation of rna biosynthetic process GO:1902680 197 0.058
anatomical structure morphogenesis GO:0009653 298 0.055
Zebrafish Mouse Fly
regulation of vesicle mediated transport GO:0060627 81 0.055
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.053
aging GO:0007568 241 0.053
positive regulation of signaling GO:0023056 270 0.049
regulation of catabolic process GO:0009894 113 0.048
positive regulation of cellular biosynthetic process GO:0031328 295 0.047
positive regulation of developmental process GO:0051094 283 0.047
response to growth factor GO:0070848 189 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.046
negative regulation of cardiac muscle tissue development GO:0055026 3 0.044
protein transport GO:0015031 132 0.043
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.042
cell cell signaling GO:0007267 335 0.041
Mouse
protein complex biogenesis GO:0070271 263 0.041
rna metabolic process GO:0016070 406 0.039
catabolic process GO:0009056 351 0.038
negative regulation of rna metabolic process GO:0051253 123 0.037
homeostatic process GO:0042592 331 0.037
negative regulation of cellular biosynthetic process GO:0031327 161 0.036
establishment of protein localization GO:0045184 141 0.036
Human
regulation of transcription dna templated GO:0006355 374 0.036
response to glucocorticoid GO:0051384 223 0.035
cellular macromolecule localization GO:0070727 122 0.035
secretion by cell GO:0032940 248 0.035
Mouse
response to biotic stimulus GO:0009607 226 0.035
regulation of phosphate metabolic process GO:0019220 349 0.033
anatomical structure formation involved in morphogenesis GO:0048646 83 0.033
Zebrafish
positive regulation of molecular function GO:0044093 230 0.033
single organism organelle organization GO:1902589 180 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
organophosphate metabolic process GO:0019637 370 0.032
synaptic transmission GO:0007268 235 0.031
Mouse
regulation of phosphorylation GO:0042325 248 0.031
response to other organism GO:0051707 220 0.031
protein complex subunit organization GO:0071822 302 0.031
nitrogen compound transport GO:0071705 229 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
cell projection organization GO:0030030 302 0.030
negative regulation of biosynthetic process GO:0009890 168 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
reproduction GO:0000003 245 0.029
regulation of signal transduction GO:0009966 318 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
response to external biotic stimulus GO:0043207 221 0.028
blood circulation GO:0008015 183 0.028
intracellular signal transduction GO:0035556 314 0.028
single organism intracellular transport GO:1902582 166 0.028
negative regulation of heart growth GO:0061117 3 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
Human Mouse Fly
intracellular transport GO:0046907 185 0.028
protein complex assembly GO:0006461 263 0.028
cell motility GO:0048870 202 0.027
Fly
cardiovascular system development GO:0072358 134 0.027
Zebrafish Mouse
regulation of protein modification process GO:0031399 194 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
single organism cellular localization GO:1902580 102 0.027
neuron differentiation GO:0030182 368 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
muscle structure development GO:0061061 87 0.026
positive regulation of transport GO:0051050 245 0.026
response to inorganic substance GO:0010035 377 0.026
ras protein signal transduction GO:0007265 29 0.025
Human Fly
g protein coupled receptor signaling pathway GO:0007186 242 0.025
negative regulation of rna biosynthetic process GO:1902679 118 0.025
regulation of multicellular organismal development GO:2000026 376 0.024
regulation of cellular component organization GO:0051128 368 0.024
cellular protein localization GO:0034613 122 0.024
response to toxic substance GO:0009636 133 0.024
chemical homeostasis GO:0048878 292 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
negative regulation of metabolic process GO:0009892 331 0.024
positive regulation of cell communication GO:0010647 271 0.024
single organism reproductive process GO:0044702 297 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
programmed cell death GO:0012501 392 0.023
reproductive process GO:0022414 372 0.023
positive regulation of secretion GO:0051047 140 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
circulatory system development GO:0072359 134 0.022
Zebrafish Mouse
macromolecular complex assembly GO:0065003 273 0.022
hormone transport GO:0009914 121 0.022
regulation of protein metabolic process GO:0051246 289 0.022
neuron projection development GO:0031175 273 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
cytosolic calcium ion homeostasis GO:0051480 140 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
negative regulation of gene expression GO:0010629 199 0.021
regulation of secretion GO:0051046 224 0.021
Mouse
actin filament based process GO:0030029 86 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
regulation of ion transport GO:0043269 245 0.021
oxoacid metabolic process GO:0043436 290 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.020
regulation of cell proliferation GO:0042127 359 0.020
multicellular organism reproduction GO:0032504 233 0.020
transmembrane transport GO:0055085 412 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
muscle cell proliferation GO:0033002 84 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
signal release GO:0023061 145 0.019
Mouse
hormone secretion GO:0046879 115 0.019
organelle organization GO:0006996 266 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
cellular amine metabolic process GO:0044106 38 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
neuron development GO:0048666 286 0.019
negative regulation of secretion by cell GO:1903531 72 0.019
Mouse
multicellular organismal reproductive process GO:0048609 233 0.019
positive regulation of protein modification process GO:0031401 142 0.019
regulation of cell differentiation GO:0045595 320 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
regulation of cell development GO:0060284 263 0.018
regulation of synaptic transmission GO:0050804 141 0.018
Mouse
response to hexose GO:0009746 144 0.018
regulation of secretion by cell GO:1903530 208 0.018
Mouse
regulation of blood circulation GO:1903522 110 0.018
positive regulation of gene expression GO:0010628 244 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
peptide transport GO:0015833 97 0.018
regulation of catalytic activity GO:0050790 304 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
positive regulation of nervous system development GO:0051962 178 0.018
ion transmembrane transport GO:0034220 365 0.018
apoptotic process GO:0006915 381 0.017
cellular response to stress GO:0033554 269 0.017
cellular ion homeostasis GO:0006873 184 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
organic acid metabolic process GO:0006082 292 0.017
cellular catabolic process GO:0044248 295 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of purine nucleotide catabolic process GO:0033121 65 0.017
regulation of cell adhesion GO:0030155 52 0.017
Fly
cellular homeostasis GO:0019725 252 0.017
response to bacterium GO:0009617 200 0.017
response to metal ion GO:0010038 253 0.017
tissue morphogenesis GO:0048729 22 0.017
Zebrafish Fly
regulation of programmed cell death GO:0043067 341 0.016
amide transport GO:0042886 105 0.016
regeneration GO:0031099 163 0.016
developmental process involved in reproduction GO:0003006 159 0.016
cytoplasmic transport GO:0016482 115 0.016
blood vessel morphogenesis GO:0048514 58 0.016
Mouse
amine metabolic process GO:0009308 38 0.016
vesicle localization GO:0051648 33 0.016
Mouse
single organism biosynthetic process GO:0044711 342 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
regulation of molecular function GO:0065009 398 0.016
multi organism reproductive process GO:0044703 262 0.016
regulation of protein kinase activity GO:0045859 105 0.016
regulation of transferase activity GO:0051338 123 0.016
cellular component assembly GO:0022607 360 0.015
Human Fly
vascular process in circulatory system GO:0003018 96 0.015
circulatory system process GO:0003013 183 0.015
nucleotide metabolic process GO:0009117 279 0.015
intracellular protein transport GO:0006886 79 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
regulation of system process GO:0044057 208 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
regulation of protein localization GO:0032880 81 0.015
regulation of apoptotic process GO:0042981 335 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
membrane organization GO:0061024 94 0.015
epithelium development GO:0060429 96 0.015
Human Zebrafish Fly
positive regulation of multicellular organismal process GO:0051240 387 0.015
cellular ketone metabolic process GO:0042180 51 0.015
cellular chemical homeostasis GO:0055082 247 0.015
defense response GO:0006952 194 0.015
negative regulation of transport GO:0051051 136 0.014
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
immune response GO:0006955 104 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
regulation of membrane potential GO:0042391 110 0.014
calcium ion homeostasis GO:0055074 162 0.014
localization of cell GO:0051674 202 0.014
Fly
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.014
cell projection morphogenesis GO:0048858 123 0.014
peptide secretion GO:0002790 86 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
growth GO:0040007 165 0.014
protein oligomerization GO:0051259 191 0.014
dna metabolic process GO:0006259 96 0.014
cation homeostasis GO:0055080 195 0.014
insulin secretion GO:0030073 69 0.014
negative regulation of signaling GO:0023057 157 0.014
Mouse
ribose phosphate metabolic process GO:0019693 235 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
coenzyme metabolic process GO:0006732 86 0.014
cell growth GO:0016049 104 0.014
cellular component biogenesis GO:0044085 368 0.013
Human Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
regulation of mapk cascade GO:0043408 116 0.013
regulation of kinase activity GO:0043549 117 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
cation transmembrane transport GO:0098655 263 0.013
muscle system process GO:0003012 115 0.013
heart morphogenesis GO:0003007 3 0.013
peptide hormone secretion GO:0030072 84 0.013
cell adhesion GO:0007155 110 0.013
Fly
regulation of neurogenesis GO:0050767 247 0.013
cell cycle checkpoint GO:0000075 2 0.013
response to glucose GO:0009749 136 0.013
cellular cation homeostasis GO:0030003 180 0.013
endothelium development GO:0003158 12 0.013
Human
single organism membrane organization GO:0044802 74 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
chromatin modification GO:0016568 33 0.013
regulation of cell projection organization GO:0031344 175 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
positive regulation of cell development GO:0010720 176 0.013
biological adhesion GO:0022610 110 0.012
Fly
regulation of hydrolase activity GO:0051336 143 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
Mouse Fly
regulation of anatomical structure size GO:0090066 135 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
protein heterooligomerization GO:0051291 89 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
vasculature development GO:0001944 70 0.012
Mouse
organic hydroxy compound transport GO:0015850 77 0.012
rho protein signal transduction GO:0007266 11 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
regulation of hormone levels GO:0010817 187 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cell cycle phase transition GO:0044770 21 0.012
immune system process GO:0002376 204 0.012
Fly
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
negative regulation of secretion GO:0051048 82 0.011
Mouse
heterocycle catabolic process GO:0046700 167 0.011
cellular lipid metabolic process GO:0044255 208 0.011
response to corticosteroid GO:0031960 235 0.011
response to transforming growth factor beta GO:0071559 46 0.011
response to lipopolysaccharide GO:0032496 191 0.011
cell migration GO:0016477 197 0.011
Fly
positive regulation of catabolic process GO:0009896 78 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
metal ion homeostasis GO:0055065 186 0.011
neuron projection morphogenesis GO:0048812 122 0.011
gastrulation GO:0007369 2 0.011
multicellular organism growth GO:0035264 1 0.011
organ formation GO:0048645 3 0.011
response to peptide GO:1901652 292 0.011
response to peptide hormone GO:0043434 278 0.011
organelle localization GO:0051640 55 0.011
Mouse
mesoderm development GO:0007498 2 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
cellular response to external stimulus GO:0071496 118 0.010
developmental growth GO:0048589 100 0.010
tissue development GO:0009888 252 0.010
Human Zebrafish Fly
response to estrogen GO:0043627 232 0.010
gamete generation GO:0007276 124 0.010
dephosphorylation GO:0016311 98 0.010
female pregnancy GO:0007565 122 0.010
establishment of organelle localization GO:0051656 37 0.010
Mouse
tube development GO:0035295 89 0.010
regulation of tube size GO:0035150 89 0.010
reproductive structure development GO:0048608 128 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
cellular component movement GO:0006928 248 0.010
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.010

Rap1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.022
disease of anatomical entity DOID:7 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022
retinal disease DOID:5679 0 0.015