Rattus norvegicus

170 known processes

Gsk3b

glycogen synthase kinase 3 beta

Gsk3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.311
Human Worm Fly
negative regulation of cellular metabolic process GO:0031324 281 0.304
cellular component biogenesis GO:0044085 368 0.243
Human Fly
rna biosynthetic process GO:0032774 380 0.189
Mouse
regulation of cellular component organization GO:0051128 368 0.186
regulation of proteasomal protein catabolic process GO:0061136 4 0.165
Mouse Fly
rna metabolic process GO:0016070 406 0.148
Mouse
tissue development GO:0009888 252 0.137
Human Fly
catabolic process GO:0009056 351 0.127
Human Mouse Fly
nucleoside triphosphate metabolic process GO:0009141 144 0.124
Human
regulation of rna metabolic process GO:0051252 391 0.123
Mouse
regulation of molecular function GO:0065009 398 0.123
secretion GO:0046903 307 0.119
macromolecular complex assembly GO:0065003 273 0.118
Human
regulation of cell differentiation GO:0045595 320 0.118
regulation of protein metabolic process GO:0051246 289 0.114
regulation of cellular protein metabolic process GO:0032268 267 0.113
intracellular signal transduction GO:0035556 314 0.113
regulation of rna biosynthetic process GO:2001141 381 0.105
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.098
cellular response to stress GO:0033554 269 0.095
Human Mouse Fly
positive regulation of biosynthetic process GO:0009891 319 0.094
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.093
regulation of secretion GO:0051046 224 0.092
transcription dna templated GO:0006351 377 0.091
Mouse
vesicle mediated transport GO:0016192 181 0.089
Worm
cellular component assembly GO:0022607 360 0.089
Human Fly
negative regulation of metabolic process GO:0009892 331 0.088
positive regulation of nucleic acid templated transcription GO:1903508 197 0.087
Mouse
neuron differentiation GO:0030182 368 0.085
positive regulation of transcription dna templated GO:0045893 197 0.085
Mouse
positive regulation of developmental process GO:0051094 283 0.084
Mouse
cellular catabolic process GO:0044248 295 0.080
Human Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.080
positive regulation of phosphate metabolic process GO:0045937 262 0.076
Human Mouse
cellular component morphogenesis GO:0032989 155 0.075
neurological system process GO:0050877 219 0.075
Fly
macromolecule localization GO:0033036 252 0.074
Human Mouse Worm
organic acid metabolic process GO:0006082 292 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
Human Mouse
programmed cell death GO:0012501 392 0.071
cellular response to hormone stimulus GO:0032870 247 0.071
aromatic compound catabolic process GO:0019439 168 0.070
Human
regulation of phosphate metabolic process GO:0019220 349 0.070
regulation of phosphorus metabolic process GO:0051174 349 0.070
protein complex subunit organization GO:0071822 302 0.069
Human Worm Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.068
Mouse Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.067
Human
regulation of multicellular organismal development GO:2000026 376 0.067
synaptic growth at neuromuscular junction GO:0051124 1 0.067
Fly
response to growth factor GO:0070848 189 0.066
protein phosphorylation GO:0006468 345 0.064
secretion by cell GO:0032940 248 0.064
neuron projection development GO:0031175 273 0.064
negative regulation of rna metabolic process GO:0051253 123 0.063
calcium ion homeostasis GO:0055074 162 0.063
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.062
Human Mouse
cellular response to lipid GO:0071396 201 0.062
negative regulation of gene expression GO:0010629 199 0.061
response to nutrient levels GO:0031667 370 0.061
organelle organization GO:0006996 266 0.059
Mouse Worm Fly
regulation of protein modification process GO:0031399 194 0.059
regulation of cell development GO:0060284 263 0.059
regulation of neurogenesis GO:0050767 247 0.058
negative regulation of biosynthetic process GO:0009890 168 0.057
columnar cuboidal epithelial cell differentiation GO:0002065 8 0.057
Fly
single organism catabolic process GO:0044712 283 0.057
Human Fly
regulation of immune system process GO:0002682 123 0.057
Fly
positive regulation of cellular component organization GO:0051130 200 0.056
Human Mouse Fly
nucleic acid templated transcription GO:0097659 379 0.056
Mouse
response to nutrient GO:0007584 248 0.055
positive regulation of cell differentiation GO:0045597 217 0.054
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.054
Human Mouse
cellular response to growth factor stimulus GO:0071363 162 0.053
negative regulation of multicellular organismal process GO:0051241 203 0.053
cellular homeostasis GO:0019725 252 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.051
Mouse
cellular metal ion homeostasis GO:0006875 172 0.051
response to extracellular stimulus GO:0009991 380 0.051
learning or memory GO:0007611 90 0.051
Fly
metal ion transport GO:0030001 289 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.050
cell growth GO:0016049 104 0.050
Mouse
heterocycle catabolic process GO:0046700 167 0.050
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.050
Human
carbohydrate derivative metabolic process GO:1901135 346 0.049
Human
positive regulation of immune system process GO:0002684 90 0.049
regulation of signal transduction GO:0009966 318 0.049
nucleoside phosphate metabolic process GO:0006753 283 0.049
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.049
ribonucleotide catabolic process GO:0009261 136 0.048
Human
regulation of transcription dna templated GO:0006355 374 0.048
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.048
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.048
Mouse
neuron development GO:0048666 286 0.048
positive regulation of protein metabolic process GO:0051247 178 0.047
Mouse Fly
regulation of catalytic activity GO:0050790 304 0.047
growth GO:0040007 165 0.046
Mouse Fly
regulation of nervous system development GO:0051960 264 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.045
calcium ion transport GO:0006816 131 0.045
purine containing compound metabolic process GO:0072521 253 0.045
Human
protein complex biogenesis GO:0070271 263 0.045
Human
oxoacid metabolic process GO:0043436 290 0.045
positive regulation of nervous system development GO:0051962 178 0.044
Mouse
positive regulation of signaling GO:0023056 270 0.044
Mouse
positive regulation of nucleotide metabolic process GO:0045981 91 0.043
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.043
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.043
protein heterooligomerization GO:0051291 89 0.043
positive regulation of phosphorylation GO:0042327 177 0.043
Mouse
central nervous system development GO:0007417 311 0.043
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
positive regulation of catalytic activity GO:0043085 184 0.043
Human
cell migration GO:0016477 197 0.042
Mouse Worm
aging GO:0007568 241 0.042
regulation of neuron differentiation GO:0045664 208 0.042
signal transduction by phosphorylation GO:0023014 144 0.042
single organism reproductive process GO:0044702 297 0.041
Worm Fly
cellular response to nitrogen compound GO:1901699 210 0.041
cellular response to organonitrogen compound GO:0071417 197 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.041
Mouse
glandular epithelial cell differentiation GO:0002067 4 0.041
single organism intracellular transport GO:1902582 166 0.041
Human Mouse
response to inorganic substance GO:0010035 377 0.040
carboxylic acid metabolic process GO:0019752 289 0.040
negative regulation of rna biosynthetic process GO:1902679 118 0.040
regulation of intracellular signal transduction GO:1902531 218 0.039
nucleotide metabolic process GO:0009117 279 0.039
Human
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.039
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.039
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
Mouse
chemical homeostasis GO:0048878 292 0.038
cell motility GO:0048870 202 0.038
Mouse Worm
protein localization GO:0008104 191 0.037
Human Mouse Worm
ribonucleotide metabolic process GO:0009259 231 0.037
Human
homeostatic process GO:0042592 331 0.037
regulation of hydrolase activity GO:0051336 143 0.037
Human
purine nucleotide metabolic process GO:0006163 229 0.037
Human
cellular response to organic cyclic compound GO:0071407 202 0.037
brain development GO:0007420 247 0.036
Human
enzyme linked receptor protein signaling pathway GO:0007167 116 0.036
cellular chemical homeostasis GO:0055082 247 0.036
cell type specific apoptotic process GO:0097285 134 0.035
regulation of purine nucleotide metabolic process GO:1900542 115 0.035
Human
nucleobase containing compound catabolic process GO:0034655 152 0.035
Human
regulation of cellular localization GO:0060341 263 0.035
Human Mouse Worm
head development GO:0060322 247 0.035
Human
metal ion homeostasis GO:0055065 186 0.035
purine ribonucleotide metabolic process GO:0009150 227 0.035
Human
response to glucocorticoid GO:0051384 223 0.034
multi organism reproductive process GO:0044703 262 0.034
Worm Fly
response to oxygen levels GO:0070482 265 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
Human
regulation of cell proliferation GO:0042127 359 0.033
biological adhesion GO:0022610 110 0.033
Human
anatomical structure morphogenesis GO:0009653 298 0.033
regulation of cell projection organization GO:0031344 175 0.033
cellular calcium ion homeostasis GO:0006874 160 0.033
exocytosis GO:0006887 60 0.033
nucleoside metabolic process GO:0009116 179 0.033
Human
ion homeostasis GO:0050801 212 0.032
positive regulation of protein phosphorylation GO:0001934 135 0.032
Mouse
purine containing compound catabolic process GO:0072523 138 0.032
Human
divalent inorganic cation homeostasis GO:0072507 165 0.032
positive regulation of gene expression GO:0010628 244 0.032
Mouse
nucleotide catabolic process GO:0009166 139 0.031
Human
response to peptide hormone GO:0043434 278 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.031
positive regulation of cell communication GO:0010647 271 0.031
Mouse
cell cell signaling GO:0007267 335 0.031
purine ribonucleoside metabolic process GO:0046128 168 0.030
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.030
membrane organization GO:0061024 94 0.030
Mouse Worm
neuron projection morphogenesis GO:0048812 122 0.030
reproductive process GO:0022414 372 0.030
Worm Fly
cation homeostasis GO:0055080 195 0.030
negative regulation of cell communication GO:0010648 158 0.030
negative regulation of response to stimulus GO:0048585 155 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.029
Human
negative regulation of cellular protein metabolic process GO:0032269 106 0.029
muscle structure development GO:0061061 87 0.029
Mouse
regulation of ion transport GO:0043269 245 0.029
regulation of protein localization GO:0032880 81 0.029
Human Worm
positive regulation of cell proliferation GO:0008284 249 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
Mouse
purine nucleoside metabolic process GO:0042278 169 0.028
Human
positive regulation of response to stimulus GO:0048584 285 0.028
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.028
reproduction GO:0000003 245 0.028
Worm Fly
negative regulation of cell death GO:0060548 229 0.028
Human Mouse
purine ribonucleotide catabolic process GO:0009154 136 0.027
Human
response to hypoxia GO:0001666 231 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
regulation of cell migration GO:0030334 128 0.027
cell morphogenesis GO:0000902 142 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
response to decreased oxygen levels GO:0036293 237 0.027
divalent metal ion transport GO:0070838 132 0.027
regulation of vesicle mediated transport GO:0060627 81 0.027
protein complex assembly GO:0006461 263 0.027
Human
cyclic nucleotide metabolic process GO:0009187 80 0.027
regulation of catabolic process GO:0009894 113 0.027
Human Mouse Fly
regulation of protein kinase activity GO:0045859 105 0.027
purine nucleotide biosynthetic process GO:0006164 83 0.026
cell cycle process GO:0022402 57 0.026
Mouse Worm Fly
glycosyl compound catabolic process GO:1901658 126 0.026
Human
single organism membrane organization GO:0044802 74 0.026
Mouse
organic substance catabolic process GO:1901575 316 0.026
Human Mouse Fly
regulation of synaptic transmission GO:0050804 141 0.026
tube development GO:0035295 89 0.026
response to bacterium GO:0009617 200 0.026
nucleoside triphosphate catabolic process GO:0009143 123 0.026
Human
ribose phosphate metabolic process GO:0019693 235 0.025
Human
proteolysis GO:0006508 175 0.025
Mouse Fly
divalent inorganic cation transport GO:0072511 134 0.025
response to biotic stimulus GO:0009607 226 0.025
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 119 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.025
positive regulation of cell development GO:0010720 176 0.025
Mouse
regulation of exocytosis GO:0017157 37 0.025
response to cytokine GO:0034097 215 0.024
Mouse
ras protein signal transduction GO:0007265 29 0.024
synaptic transmission GO:0007268 235 0.024
response to other organism GO:0051707 220 0.024
cation transport GO:0006812 382 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
Human Mouse
sequestering of metal ion GO:0051238 9 0.024
cellular ion homeostasis GO:0006873 184 0.024
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.024
positive regulation of molecular function GO:0044093 230 0.024
Human Mouse
cellular response to peptide hormone stimulus GO:0071375 120 0.024
cellular cation homeostasis GO:0030003 180 0.023
regulation of anatomical structure size GO:0090066 135 0.023
Mouse
single organism biosynthetic process GO:0044711 342 0.023
organophosphate metabolic process GO:0019637 370 0.023
Human
immune system process GO:0002376 204 0.023
Fly
response to corticosteroid GO:0031960 235 0.023
negative regulation of molecular function GO:0044092 133 0.023
protein oligomerization GO:0051259 191 0.023
chromosome segregation GO:0007059 2 0.023
Fly
locomotion GO:0040011 237 0.023
Mouse Worm
response to wounding GO:0009611 254 0.022
negative regulation of signaling GO:0023057 157 0.022
regulation of nucleotide metabolic process GO:0006140 117 0.022
Human
regulation of cellular catabolic process GO:0031329 101 0.022
Human Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
guanosine containing compound metabolic process GO:1901068 74 0.022
Human
small gtpase mediated signal transduction GO:0007264 36 0.022
response to lipopolysaccharide GO:0032496 191 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
Human
multicellular organism reproduction GO:0032504 233 0.022
Worm Fly
nucleotide biosynthetic process GO:0009165 98 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
Human Mouse
regulation of calcium ion transport GO:0051924 77 0.022
response to estrogen GO:0043627 232 0.022
response to acid chemical GO:0001101 222 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
response to peptide GO:1901652 292 0.022
cell projection morphogenesis GO:0048858 123 0.022
organelle localization GO:0051640 55 0.022
Worm
ribonucleoside metabolic process GO:0009119 174 0.022
Human
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
cellular response to external stimulus GO:0071496 118 0.021
regulation of locomotion GO:0040012 148 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
Mouse
organelle assembly GO:0070925 22 0.021
cell projection organization GO:0030030 302 0.021
mapk cascade GO:0000165 140 0.021
muscle cell proliferation GO:0033002 84 0.021
positive regulation of mapk cascade GO:0043410 92 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
localization of cell GO:0051674 202 0.020
Mouse Worm
organic cyclic compound catabolic process GO:1901361 175 0.020
Human
regulation of neuron death GO:1901214 115 0.020
apoptotic process GO:0006915 381 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
Fly
regulation of apoptotic process GO:0042981 335 0.020
eye morphogenesis GO:0048592 4 0.020
positive regulation of signal transduction GO:0009967 175 0.020
Mouse
cellular amine metabolic process GO:0044106 38 0.020
ribonucleotide biosynthetic process GO:0009260 85 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.019
cellular macromolecule localization GO:0070727 122 0.019
Human Mouse
nucleoside catabolic process GO:0009164 126 0.019
Human
cognition GO:0050890 92 0.019
Fly
regulation of calcineurin nfat signaling cascade GO:0070884 3 0.019
Fly
cellular amino acid metabolic process GO:0006520 107 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
regulation of homeostatic process GO:0032844 101 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
sexual reproduction GO:0019953 148 0.019
Worm Fly
behavior GO:0007610 205 0.019
Fly
response to external biotic stimulus GO:0043207 221 0.019
purine nucleoside catabolic process GO:0006152 124 0.018
Human
muscle cell differentiation GO:0042692 52 0.018
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.018
Mouse
regulation of protein phosphorylation GO:0001932 183 0.018
regulation of metal ion transport GO:0010959 118 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
Mouse
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
guanosine containing compound catabolic process GO:1901069 71 0.018
Human
regulation of secretion by cell GO:1903530 208 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
single organism organelle organization GO:1902589 180 0.018
Mouse Worm Fly
purine containing compound biosynthetic process GO:0072522 85 0.018
regulation of membrane potential GO:0042391 110 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
intracellular transport GO:0046907 185 0.018
Human Mouse
circulatory system process GO:0003013 183 0.018
pattern recognition receptor signaling pathway GO:0002221 9 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
cellular ketone metabolic process GO:0042180 51 0.018
bmp signaling pathway GO:0030509 4 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
Human Fly
negative regulation of developmental process GO:0051093 125 0.018
response to estradiol GO:0032355 164 0.018
positive regulation of immunoglobulin production GO:0002639 4 0.018
carbon catabolite activation of transcription GO:0045991 1 0.018
negative regulation of transport GO:0051051 136 0.018
Human
amine metabolic process GO:0009308 38 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
regulation of cell motility GO:2000145 131 0.017
camp biosynthetic process GO:0006171 47 0.017
positive regulation of transferase activity GO:0051347 81 0.017
anterior posterior pattern specification GO:0009952 1 0.017
regulation of programmed cell death GO:0043067 341 0.017
taxis GO:0042330 67 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
regulation of system process GO:0044057 208 0.017
Mouse
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
regulation of cell morphogenesis GO:0022604 77 0.017
regulation of ion homeostasis GO:2000021 63 0.017
gastrulation GO:0007369 2 0.017
regulation of defense response GO:0031347 68 0.017
regulation of behavior GO:0050795 61 0.017
negative regulation of kidney development GO:0090185 2 0.017
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.017
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 5 0.017
axon development GO:0061564 96 0.017
Mouse
organophosphate catabolic process GO:0046434 148 0.017
Human
positive regulation of apoptotic process GO:0043065 154 0.017
cardiovascular system development GO:0072358 134 0.017
response to insulin GO:0032868 133 0.016
b cell differentiation GO:0030183 2 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
Human
response to metal ion GO:0010038 253 0.016
somatic stem cell maintenance GO:0035019 2 0.016
Fly
defense response GO:0006952 194 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
Human
camp metabolic process GO:0046058 63 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of innate immune response GO:0045824 4 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
atp metabolic process GO:0046034 72 0.016
transmembrane transport GO:0055085 412 0.016
reproductive structure development GO:0048608 128 0.016
Worm Fly
positive regulation of cell death GO:0010942 184 0.016
regulation of nucleotide biosynthetic process GO:0030808 47 0.015
sequestering of calcium ion GO:0051208 8 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
activation of protein kinase activity GO:0032147 47 0.015
developmental growth GO:0048589 100 0.015
Mouse Fly
regulation of mapk cascade GO:0043408 116 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
response to vitamin GO:0033273 131 0.015
regulation of phosphorylation GO:0042325 248 0.015
actin filament based process GO:0030029 86 0.015
embryonic skeletal system morphogenesis GO:0048704 3 0.015
response to mineralocorticoid GO:0051385 49 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
Mouse
ion transmembrane transport GO:0034220 365 0.015
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.015
cellular component movement GO:0006928 248 0.015
Mouse Worm
leukocyte activation GO:0045321 76 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
Mouse
chemotaxis GO:0006935 66 0.015
response to toxic substance GO:0009636 133 0.015
heart development GO:0007507 72 0.015
centrosome organization GO:0051297 1 0.015
spermatogenesis GO:0007283 99 0.014
carboxylic acid transport GO:0046942 115 0.014
epithelial cell differentiation GO:0030855 71 0.014
Fly
wound healing GO:0042060 122 0.014
regulation of kinase activity GO:0043549 117 0.014
negative regulation of cell development GO:0010721 82 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
axis specification GO:0009798 4 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
epithelium development GO:0060429 96 0.014
Fly
microtubule organizing center organization GO:0031023 1 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
calcium ion transport into cytosol GO:0060402 38 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
Mouse
posttranscriptional regulation of gene expression GO:0010608 37 0.014
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.014
immune response GO:0006955 104 0.014
gtp metabolic process GO:0046039 72 0.014
Human
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
cell activation GO:0001775 97 0.014
regulation of cell growth GO:0001558 85 0.014
Mouse
peptidyl amino acid modification GO:0018193 126 0.013
Human Mouse Worm
negative regulation of signal transduction GO:0009968 83 0.013
response to carbohydrate GO:0009743 183 0.013
positive regulation of kinase activity GO:0033674 77 0.013
response to ammonium ion GO:0060359 71 0.013
developmental process involved in reproduction GO:0003006 159 0.013
Worm Fly
negative regulation of cellular component organization GO:0051129 83 0.013
urogenital system development GO:0001655 78 0.013
cellular response to peptide GO:1901653 133 0.013
positive regulation of nitric oxide synthase activity GO:0051000 5 0.013
male gamete generation GO:0048232 99 0.013
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
negative regulation of intracellular signal transduction GO:1902532 38 0.013
endomembrane system organization GO:0010256 48 0.013
mesenchymal cell proliferation GO:0010463 4 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
Human
purine nucleotide catabolic process GO:0006195 136 0.013
Human
positive regulation of ion transport GO:0043270 94 0.013
second messenger mediated signaling GO:0019932 51 0.013
Fly
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
cellular response to molecule of bacterial origin GO:0071219 56 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
Worm Fly
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
Human
ncrna processing GO:0034470 3 0.012
spindle organization GO:0007051 2 0.012
Worm Fly
negative regulation of homeostatic process GO:0032845 47 0.012
regulation of chemotaxis GO:0050920 29 0.012
response to monosaccharide GO:0034284 159 0.012
multicellular organism growth GO:0035264 1 0.012
liver development GO:0001889 90 0.012
response to oxidative stress GO:0006979 186 0.012
telencephalon development GO:0021537 62 0.012
Human
action potential GO:0001508 54 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
embryonic pattern specification GO:0009880 1 0.012
Fly
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.012
mrna processing GO:0006397 14 0.012
regulation of hormone levels GO:0010817 187 0.012
developmental induction GO:0031128 2 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.012
response to camp GO:0051591 91 0.012
regulation of neuron projection development GO:0010975 161 0.012
positive regulation of transport GO:0051050 245 0.012
Human Mouse
regulation of nitric oxide synthase activity GO:0050999 8 0.012
response to alkaloid GO:0043279 132 0.012
actin cytoskeleton organization GO:0030036 73 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
regulation of leukocyte differentiation GO:1902105 20 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
kidney development GO:0001822 67 0.012
nitrogen compound transport GO:0071705 229 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.012
carbohydrate homeostasis GO:0033500 75 0.012
camera type eye development GO:0043010 48 0.011
positive regulation of secretion GO:0051047 140 0.011
regulation of gtpase activity GO:0043087 57 0.011
Human
regulation of immunoglobulin production GO:0002637 4 0.011
neuronal action potential GO:0019228 35 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
response to mechanical stimulus GO:0009612 134 0.011
response to transforming growth factor beta GO:0071559 46 0.011
artery development GO:0060840 3 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of cellular component movement GO:0051270 150 0.011
positive regulation of cyclase activity GO:0031281 15 0.011
translation GO:0006412 35 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regeneration GO:0031099 163 0.011
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.011
gliogenesis GO:0042063 93 0.011
dna metabolic process GO:0006259 96 0.011
Mouse
regulation of immunoglobulin secretion GO:0051023 1 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
negative regulation of metanephros development GO:0072217 2 0.011
regulation of gene expression epigenetic GO:0040029 10 0.011
Mouse
respiratory system development GO:0060541 45 0.011
regulation of transferase activity GO:0051338 123 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011

Gsk3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
gastrointestinal system cancer DOID:3119 0 0.013
colon carcinoma DOID:1520 0 0.013
large intestine cancer DOID:5672 0 0.013
colon cancer DOID:219 0 0.013
intestinal cancer DOID:10155 0 0.013
colorectal cancer DOID:9256 0 0.013