Rattus norvegicus

0 known processes

Gabarapl2

GABA(A) receptor-associated protein like 2

(Aliases: MGC108686,Gef2)

Gabarapl2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
c21 steroid hormone biosynthetic process GO:0006700 10 0.358
regulation of programmed cell death GO:0043067 341 0.356
postsynaptic density protein 95 clustering GO:0097119 2 0.351
apoptotic process GO:0006915 381 0.345
regulation of cellular localization GO:0060341 263 0.296
cellular protein localization GO:0034613 122 0.228
single organism cellular localization GO:1902580 102 0.196
protein localization GO:0008104 191 0.194
cellular macromolecule localization GO:0070727 122 0.194
macromolecule localization GO:0033036 252 0.178
single organism intracellular transport GO:1902582 166 0.162
organophosphate biosynthetic process GO:0090407 143 0.161
single organism biosynthetic process GO:0044711 342 0.158
establishment of protein localization to organelle GO:0072594 44 0.155
response to inorganic substance GO:0010035 377 0.151
progesterone biosynthetic process GO:0006701 3 0.148
c21 steroid hormone metabolic process GO:0008207 14 0.123
intracellular transport GO:0046907 185 0.115
cellular ketone metabolic process GO:0042180 51 0.111
negative regulation of multicellular organismal process GO:0051241 203 0.108
negative regulation of apoptotic process GO:0043066 181 0.099
programmed cell death GO:0012501 392 0.097
negative regulation of programmed cell death GO:0043069 183 0.097
regulation of apoptotic process GO:0042981 335 0.083
regulation of intracellular signal transduction GO:1902531 218 0.080
regulation of cell proliferation GO:0042127 359 0.078
regulation of phosphate metabolic process GO:0019220 349 0.077
positive regulation of cell communication GO:0010647 271 0.076
intracellular signal transduction GO:0035556 314 0.075
reproductive process GO:0022414 372 0.074
cellular amino acid metabolic process GO:0006520 107 0.073
cellular catabolic process GO:0044248 295 0.073
Human Rat
positive regulation of biosynthetic process GO:0009891 319 0.067
regulation of signal transduction GO:0009966 318 0.063
protein complex subunit organization GO:0071822 302 0.061
regulation of protein metabolic process GO:0051246 289 0.060
Human
negative regulation of cell death GO:0060548 229 0.059
cellular response to oxygen containing compound GO:1901701 386 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.056
oxoacid metabolic process GO:0043436 290 0.056
purine containing compound biosynthetic process GO:0072522 85 0.055
alcohol metabolic process GO:0006066 77 0.054
glutathione metabolic process GO:0006749 15 0.053
cellular response to organonitrogen compound GO:0071417 197 0.051
organic acid metabolic process GO:0006082 292 0.050
positive regulation of transport GO:0051050 245 0.047
catabolic process GO:0009056 351 0.046
Human Rat
cholesterol transport GO:0030301 5 0.046
lipid metabolic process GO:0006629 283 0.043
negative regulation of protein metabolic process GO:0051248 114 0.043
Human
lipid transport GO:0006869 61 0.041
secretion by cell GO:0032940 248 0.039
cellular response to endogenous stimulus GO:0071495 377 0.038
response to peptide GO:1901652 292 0.037
protein localization to membrane GO:0072657 36 0.036
purine nucleotide biosynthetic process GO:0006164 83 0.036
regulation of cellular component organization GO:0051128 368 0.035
lipid biosynthetic process GO:0008610 128 0.035
sexual reproduction GO:0019953 148 0.035
central nervous system development GO:0007417 311 0.035
cellular response to hormone stimulus GO:0032870 247 0.034
cellular amine metabolic process GO:0044106 38 0.034
nucleotide biosynthetic process GO:0009165 98 0.033
protein targeting GO:0006605 61 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
protein phosphorylation GO:0006468 345 0.031
response to insulin GO:0032868 133 0.031
brain development GO:0007420 247 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
cellular response to stress GO:0033554 269 0.030
Rat
positive regulation of signaling GO:0023056 270 0.030
head development GO:0060322 247 0.029
amine metabolic process GO:0009308 38 0.029
regulation of transcription dna templated GO:0006355 374 0.029
protein transport GO:0015031 132 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
nucleic acid templated transcription GO:0097659 379 0.028
regulation of protein kinase activity GO:0045859 105 0.028
nucleoside monophosphate catabolic process GO:0009125 56 0.028
regulation of ion transport GO:0043269 245 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
Human
establishment of protein localization GO:0045184 141 0.027
hormone metabolic process GO:0042445 69 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
negative regulation of gene expression GO:0010629 199 0.026
Human
negative regulation of response to stimulus GO:0048585 155 0.025
peptide biosynthetic process GO:0043043 3 0.025
regulation of hormone levels GO:0010817 187 0.025
calcium ion transport GO:0006816 131 0.025
intracellular protein transport GO:0006886 79 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
multicellular organism reproduction GO:0032504 233 0.023
nitrogen compound transport GO:0071705 229 0.023
cellular response to insulin stimulus GO:0032869 81 0.023
carbohydrate metabolic process GO:0005975 130 0.023
single organism organelle organization GO:1902589 180 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
gamete generation GO:0007276 124 0.023
regulation of metal ion transport GO:0010959 118 0.023
positive regulation of transferase activity GO:0051347 81 0.023
positive regulation of signal transduction GO:0009967 175 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
organic hydroxy compound biosynthetic process GO:1901617 51 0.022
response to oxidative stress GO:0006979 186 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
neuron apoptotic process GO:0051402 88 0.022
negative regulation of metabolic process GO:0009892 331 0.022
Human
multi organism reproductive process GO:0044703 262 0.022
regulation of catalytic activity GO:0050790 304 0.021
organelle organization GO:0006996 266 0.021
Rat
metal ion transport GO:0030001 289 0.021
protein localization to organelle GO:0033365 57 0.021
regulation of transferase activity GO:0051338 123 0.021
regulation of phosphorylation GO:0042325 248 0.021
organic hydroxy compound metabolic process GO:1901615 115 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
hormone biosynthetic process GO:0042446 25 0.021
cellular response to peptide GO:1901653 133 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
positive regulation of response to stimulus GO:0048584 285 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
sterol transport GO:0015918 6 0.020
cellular component biogenesis GO:0044085 368 0.019
Rat
transcription dna templated GO:0006351 377 0.019
postsynaptic membrane organization GO:0001941 5 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
organophosphate metabolic process GO:0019637 370 0.019
inositol trisphosphate biosynthetic process GO:0032959 3 0.019
cell cycle GO:0007049 101 0.019
regulation of lipid metabolic process GO:0019216 68 0.019
steroid biosynthetic process GO:0006694 48 0.018
positive regulation of leukocyte proliferation GO:0070665 20 0.018
divalent inorganic cation transport GO:0072511 134 0.018
cellular response to external stimulus GO:0071496 118 0.018
Rat
cofactor metabolic process GO:0051186 95 0.018
homeostatic process GO:0042592 331 0.018
peroxisome organization GO:0007031 6 0.018
dna integrity checkpoint GO:0031570 2 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.017
organic hydroxy compound transport GO:0015850 77 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
secretion GO:0046903 307 0.017
reproductive system development GO:0061458 128 0.017
response to metal ion GO:0010038 253 0.017
male gamete generation GO:0048232 99 0.017
positive regulation of lymphocyte proliferation GO:0050671 20 0.017
positive regulation of cellular component organization GO:0051130 200 0.016
response to cytokine GO:0034097 215 0.016
response to toxic substance GO:0009636 133 0.016
negative regulation of signaling GO:0023057 157 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
organic substance catabolic process GO:1901575 316 0.016
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
aging GO:0007568 241 0.015
immune system process GO:0002376 204 0.015
regulation of kinase activity GO:0043549 117 0.015
rna biosynthetic process GO:0032774 380 0.015
microtubule based process GO:0007017 36 0.015
cellular modified amino acid metabolic process GO:0006575 61 0.015
autophagic cell death GO:0048102 4 0.015
centrosome organization GO:0051297 1 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
response to ethanol GO:0045471 162 0.015
polyol biosynthetic process GO:0046173 13 0.015
neuron death GO:0070997 127 0.015
regulation of protein maturation GO:1903317 50 0.015
Human
ribonucleotide biosynthetic process GO:0009260 85 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
chemical homeostasis GO:0048878 292 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
Human
positive regulation of lipid biosynthetic process GO:0046889 25 0.014
coenzyme metabolic process GO:0006732 86 0.014
regulation of cell differentiation GO:0045595 320 0.014
regulation of protein localization GO:0032880 81 0.014
inositol trisphosphate metabolic process GO:0032957 4 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
protein complex biogenesis GO:0070271 263 0.013
regulation of protein modification process GO:0031399 194 0.013
growth GO:0040007 165 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
positive regulation of lipid metabolic process GO:0045834 33 0.013
positive regulation of lipid kinase activity GO:0090218 2 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
single organism reproductive process GO:0044702 297 0.013
spindle organization GO:0007051 2 0.013
regulation of calcium ion transport GO:0051924 77 0.013
response to nutrient levels GO:0031667 370 0.013
Rat
neuron development GO:0048666 286 0.013
negative regulation of immune system process GO:0002683 39 0.013
mitotic dna damage checkpoint GO:0044773 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
positive regulation of intracellular transport GO:0032388 39 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of intracellular transport GO:0032386 65 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
protein complex assembly GO:0006461 263 0.012
sulfur compound metabolic process GO:0006790 70 0.012
mesoderm development GO:0007498 2 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
negative regulation of transport GO:0051051 136 0.012
mitotic spindle organization GO:0007052 2 0.012
regulation of body fluid levels GO:0050878 90 0.012
developmental process involved in reproduction GO:0003006 159 0.012
oxidation reduction process GO:0055114 304 0.012
nonribosomal peptide biosynthetic process GO:0019184 3 0.012
regulation of transporter activity GO:0032409 50 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
lipid localization GO:0010876 62 0.012
small gtpase mediated signal transduction GO:0007264 36 0.011
gliogenesis GO:0042063 93 0.011
regulation of leukocyte proliferation GO:0070663 26 0.011
cytoskeleton organization GO:0007010 111 0.011
response to hypoxia GO:0001666 231 0.011
regulation of locomotion GO:0040012 148 0.011
regulation of cell motility GO:2000145 131 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
salivary gland development GO:0007431 3 0.011
response to amphetamine GO:0001975 25 0.011
cellular hormone metabolic process GO:0034754 49 0.011
cell type specific apoptotic process GO:0097285 134 0.011
single organism membrane organization GO:0044802 74 0.011
cellular component assembly GO:0022607 360 0.011
Rat
cellular component movement GO:0006928 248 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
cellular ion homeostasis GO:0006873 184 0.011
cellular amide metabolic process GO:0043603 44 0.011
ion homeostasis GO:0050801 212 0.011
cellular chemical homeostasis GO:0055082 247 0.011
cell adhesion GO:0007155 110 0.011
regulation of molecular function GO:0065009 398 0.011
Rat
cellular response to extracellular stimulus GO:0031668 73 0.010
Rat
regulation of growth GO:0040008 105 0.010
dna metabolic process GO:0006259 96 0.010
ras protein signal transduction GO:0007265 29 0.010
divalent metal ion transport GO:0070838 132 0.010
response to ketone GO:1901654 182 0.010
cell projection organization GO:0030030 302 0.010
single organism catabolic process GO:0044712 283 0.010
Rat
inositol phosphate metabolic process GO:0043647 12 0.010
rna metabolic process GO:0016070 406 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
cold acclimation GO:0009631 1 0.010

Gabarapl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.047
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
retinal disease DOID:5679 0 0.027
eye and adnexa disease DOID:1492 0 0.027
eye disease DOID:5614 0 0.027
retinal degeneration DOID:8466 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011