Rattus norvegicus

52 known processes

Cyp4a2

cytochrome P450, family 4, subfamily a, polypeptide 2

(Aliases: Cyp4a11)

Cyp4a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
halogenated hydrocarbon metabolic process GO:0042197 4 0.828
chlorinated hydrocarbon metabolic process GO:0042196 4 0.574
monocarboxylic acid metabolic process GO:0032787 152 0.529
response to xenobiotic stimulus GO:0009410 23 0.497
cellular response to peptide hormone stimulus GO:0071375 120 0.457
cellular catabolic process GO:0044248 295 0.329
Rat
gland development GO:0048732 155 0.281
4 chlorobiphenyl metabolic process GO:0018880 1 0.251
hepaticobiliary system development GO:0061008 90 0.231
response to nutrient GO:0007584 248 0.208
catabolic process GO:0009056 351 0.206
Rat
biphenyl catabolic process GO:0070980 2 0.196
naphthalene metabolic process GO:0018931 2 0.194
response to ionizing radiation GO:0010212 59 0.188
response to insulin GO:0032868 133 0.187
response to metal ion GO:0010038 253 0.185
cellular response to peptide GO:1901653 133 0.182
response to inorganic substance GO:0010035 377 0.171
cellular response to glucocorticoid stimulus GO:0071385 68 0.164
lipid metabolic process GO:0006629 283 0.163
cellular response to hormone stimulus GO:0032870 247 0.162
cellular response to xenobiotic stimulus GO:0071466 19 0.152
liver development GO:0001889 90 0.144
cellular response to corticosteroid stimulus GO:0071384 69 0.143
cellular response to lipid GO:0071396 201 0.143
alkaloid metabolic process GO:0009820 3 0.139
response to cesium ion GO:0010164 2 0.136
macromolecule localization GO:0033036 252 0.134
cellular response to nitrogen compound GO:1901699 210 0.133
unsaturated fatty acid metabolic process GO:0033559 39 0.132
oxoacid metabolic process GO:0043436 290 0.130
exogenous drug catabolic process GO:0042738 1 0.129
Rat
cellular response to organonitrogen compound GO:0071417 197 0.128
trichloroethylene metabolic process GO:0018979 1 0.127
cellular lipid metabolic process GO:0044255 208 0.127
fatty acid metabolic process GO:0006631 99 0.122
drug metabolic process GO:0017144 11 0.120
Rat
response to peptide hormone GO:0043434 278 0.115
carboxylic acid metabolic process GO:0019752 289 0.113
organic acid metabolic process GO:0006082 292 0.107
response to extracellular stimulus GO:0009991 380 0.107
b cell differentiation GO:0030183 2 0.104
linoleic acid metabolic process GO:0043651 4 0.098
response to testosterone GO:0033574 55 0.095
Rat
cellular response to endogenous stimulus GO:0071495 377 0.094
cellular response to insulin stimulus GO:0032869 81 0.093
aromatic compound catabolic process GO:0019439 168 0.093
cellular response to testosterone stimulus GO:0071394 5 0.091
response to peptide GO:1901652 292 0.089
response to nutrient levels GO:0031667 370 0.088
epoxygenase p450 pathway GO:0019373 1 0.087
xenobiotic metabolic process GO:0006805 19 0.085
regeneration GO:0031099 163 0.085
phenylpropanoid metabolic process GO:0009698 5 0.083
response to glucocorticoid GO:0051384 223 0.082
long chain fatty acid metabolic process GO:0001676 32 0.081
organonitrogen compound biosynthetic process GO:1901566 167 0.076
organ regeneration GO:0031100 101 0.076
fatty acid derivative metabolic process GO:1901568 38 0.075
single organism catabolic process GO:0044712 283 0.075
regulation of neuron differentiation GO:0045664 208 0.075
aging GO:0007568 241 0.074
arachidonic acid metabolic process GO:0019369 20 0.073
cellular response to steroid hormone stimulus GO:0071383 93 0.073
organic substance catabolic process GO:1901575 316 0.070
organic cyclic compound catabolic process GO:1901361 175 0.069
drug catabolic process GO:0042737 1 0.067
Rat
heterocycle catabolic process GO:0046700 167 0.066
phenylpropanoid catabolic process GO:0046271 3 0.065
icosanoid metabolic process GO:0006690 38 0.064
response to radiation GO:0009314 137 0.063
cellular response to oxygen containing compound GO:1901701 386 0.062
response to transition metal nanoparticle GO:1990267 122 0.061
regulation of cell proliferation GO:0042127 359 0.058
response to ketone GO:1901654 182 0.057
Rat
response to biotic stimulus GO:0009607 226 0.056
response to molecule of bacterial origin GO:0002237 194 0.055
naphthalene containing compound metabolic process GO:0090420 2 0.054
single organism reproductive process GO:0044702 297 0.050
steroid metabolic process GO:0008202 73 0.048
xenobiotic catabolic process GO:0042178 7 0.047
cellular response to growth factor stimulus GO:0071363 162 0.046
response to growth factor GO:0070848 189 0.046
reactive oxygen species biosynthetic process GO:1903409 8 0.045
response to sulfur dioxide GO:0010477 3 0.045
response to lipopolysaccharide GO:0032496 191 0.045
nicotine metabolic process GO:0018933 1 0.044
organonitrogen compound catabolic process GO:1901565 179 0.044
response to ethanol GO:0045471 162 0.044
response to corticosteroid GO:0031960 235 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
nuclear transport GO:0051169 49 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
response to estradiol GO:0032355 164 0.040
nucleoside metabolic process GO:0009116 179 0.040
carbohydrate derivative catabolic process GO:1901136 147 0.039
response to cytokine GO:0034097 215 0.039
secondary metabolic process GO:0019748 15 0.038
response to purine containing compound GO:0014074 126 0.038
estrogen catabolic process GO:0006711 1 0.038
multi organism reproductive process GO:0044703 262 0.038
purine nucleotide metabolic process GO:0006163 229 0.037
ribonucleoside triphosphate catabolic process GO:0009203 122 0.037
regulation of molecular function GO:0065009 398 0.037
regulation of apoptotic process GO:0042981 335 0.036
cellular response to alcohol GO:0097306 87 0.036
response to epidermal growth factor GO:0070849 18 0.036
alpha amino acid metabolic process GO:1901605 71 0.035
establishment of protein localization GO:0045184 141 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
nucleoside triphosphate metabolic process GO:0009141 144 0.035
benzene containing compound metabolic process GO:0042537 22 0.034
Rat
nucleotide metabolic process GO:0009117 279 0.034
protein maturation GO:0051604 68 0.034
response to external biotic stimulus GO:0043207 221 0.034
isoprenoid metabolic process GO:0006720 45 0.034
reproductive process GO:0022414 372 0.033
cellular response to organic cyclic compound GO:0071407 202 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
positive regulation of cell death GO:0010942 184 0.033
regulation of cell development GO:0060284 263 0.033
organophosphate catabolic process GO:0046434 148 0.032
response to bacterium GO:0009617 200 0.032
regulation of neurogenesis GO:0050767 247 0.032
angiogenesis GO:0001525 53 0.031
response to other organism GO:0051707 220 0.031
apoptotic process GO:0006915 381 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
cellular ketone metabolic process GO:0042180 51 0.030
cellular response to growth hormone stimulus GO:0071378 6 0.029
protein localization GO:0008104 191 0.029
cation transport GO:0006812 382 0.029
lauric acid metabolic process GO:0048252 4 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.028
regulation of secretion by cell GO:1903530 208 0.028
secretion GO:0046903 307 0.028
response to nicotine GO:0035094 51 0.028
coumarin catabolic process GO:0046226 3 0.028
regulation of protein metabolic process GO:0051246 289 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.027
developmental process involved in reproduction GO:0003006 159 0.027
behavior GO:0007610 205 0.027
response to acid chemical GO:0001101 222 0.026
reactive oxygen species metabolic process GO:0072593 37 0.026
sexual reproduction GO:0019953 148 0.026
multicellular organism reproduction GO:0032504 233 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
macromolecular complex assembly GO:0065003 273 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
transmembrane transport GO:0055085 412 0.025
response to decreased oxygen levels GO:0036293 237 0.025
intracellular signal transduction GO:0035556 314 0.025
purine ribonucleotide catabolic process GO:0009154 136 0.025
response to starvation GO:0042594 59 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
cellular response to cytokine stimulus GO:0071345 127 0.025
reactive nitrogen species metabolic process GO:2001057 1 0.024
purine containing compound catabolic process GO:0072523 138 0.024
cation homeostasis GO:0055080 195 0.024
response to reactive oxygen species GO:0000302 120 0.024
regulation of anatomical structure size GO:0090066 135 0.024
regulation of cell differentiation GO:0045595 320 0.024
organic acid biosynthetic process GO:0016053 83 0.024
purine nucleoside triphosphate metabolic process GO:0009144 141 0.024
defense response GO:0006952 194 0.023
negative regulation of protein maturation GO:1903318 47 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
inflammatory response GO:0006954 150 0.023
coumarin metabolic process GO:0009804 5 0.023
sensory organ development GO:0007423 74 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
glycosyl compound metabolic process GO:1901657 182 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
regulation of reactive oxygen species metabolic process GO:2000377 26 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
ribonucleoside triphosphate metabolic process GO:0009199 141 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.022
positive regulation of cell development GO:0010720 176 0.022
muscle structure development GO:0061061 87 0.022
reproduction GO:0000003 245 0.022
cellular amino acid metabolic process GO:0006520 107 0.021
lipid storage GO:0019915 1 0.021
regulation of programmed cell death GO:0043067 341 0.021
response to toxic substance GO:0009636 133 0.021
Rat
terpenoid metabolic process GO:0006721 37 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
pyridine containing compound metabolic process GO:0072524 32 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
response to amino acid GO:0043200 75 0.021
cellular component assembly GO:0022607 360 0.021
protein localization to organelle GO:0033365 57 0.021
ribonucleotide catabolic process GO:0009261 136 0.020
neurological system process GO:0050877 219 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
gamete generation GO:0007276 124 0.020
rhythmic process GO:0048511 156 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
response to vitamin GO:0033273 131 0.020
cellular response to ethanol GO:0071361 13 0.020
olfactory learning GO:0008355 1 0.020
protein transport GO:0015031 132 0.019
response to estrogen GO:0043627 232 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
chemosensory behavior GO:0007635 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
mapk cascade GO:0000165 140 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
negative regulation of developmental process GO:0051093 125 0.019
nucleotide catabolic process GO:0009166 139 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
olfactory behavior GO:0042048 2 0.018
acylglycerol metabolic process GO:0006639 21 0.018
phenol containing compound metabolic process GO:0018958 30 0.018
metal ion homeostasis GO:0055065 186 0.018
response to herbicide GO:0009635 16 0.018
regulation of neuron projection development GO:0010975 161 0.018
negative regulation of apoptotic process GO:0043066 181 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
regulation of hormone levels GO:0010817 187 0.017
gliogenesis GO:0042063 93 0.017
regulation of nervous system development GO:0051960 264 0.017
axis specification GO:0009798 4 0.017
nucleoside catabolic process GO:0009164 126 0.017
positive regulation of molecular function GO:0044093 230 0.017
response to monosaccharide GO:0034284 159 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
ras protein signal transduction GO:0007265 29 0.017
embryonic pattern specification GO:0009880 1 0.017
kidney development GO:0001822 67 0.017
eye morphogenesis GO:0048592 4 0.016
central nervous system development GO:0007417 311 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
response to carbohydrate GO:0009743 183 0.016
response to oxidative stress GO:0006979 186 0.016
regulation of body fluid levels GO:0050878 90 0.016
protein processing GO:0016485 68 0.016
response to organophosphorus GO:0046683 102 0.016
multi multicellular organism process GO:0044706 138 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of rna metabolic process GO:0051252 391 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
response to oxygen levels GO:0070482 265 0.015
renal system development GO:0072001 67 0.015
oxidation reduction process GO:0055114 304 0.015
hormone catabolic process GO:0042447 2 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
vasoconstriction GO:0042310 54 0.015
cellular response to external stimulus GO:0071496 118 0.015
cellular response to epidermal growth factor stimulus GO:0071364 12 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
protein complex subunit organization GO:0071822 302 0.015
single organism biosynthetic process GO:0044711 342 0.015
purine containing compound metabolic process GO:0072521 253 0.015
positive regulation of protein secretion GO:0050714 19 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of hydrolase activity GO:0051336 143 0.014
cellular component movement GO:0006928 248 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
regulation of catalytic activity GO:0050790 304 0.014
negative regulation of metabolic process GO:0009892 331 0.014
negative regulation of cell death GO:0060548 229 0.014
cellular hormone metabolic process GO:0034754 49 0.014
negative regulation of protein processing GO:0010955 47 0.014
triglyceride metabolic process GO:0006641 21 0.014
cytokine mediated signaling pathway GO:0019221 43 0.014
circulatory system development GO:0072359 134 0.014
reproductive structure development GO:0048608 128 0.013
acute inflammatory response GO:0002526 58 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of extracellular matrix constituent secretion GO:0003330 2 0.013
negative regulation of molecular function GO:0044092 133 0.013
female pregnancy GO:0007565 122 0.013
sulfur compound metabolic process GO:0006790 70 0.013
heart morphogenesis GO:0003007 3 0.013
positive regulation of blood circulation GO:1903524 65 0.013
programmed cell death GO:0012501 392 0.013
response to lead ion GO:0010288 33 0.013
gastrulation GO:0007369 2 0.013
cellular component morphogenesis GO:0032989 155 0.013
diterpenoid metabolic process GO:0016101 33 0.013
response to caffeine GO:0031000 18 0.013
steroid catabolic process GO:0006706 5 0.013
muscle tissue development GO:0060537 58 0.013
proteolysis GO:0006508 175 0.013
neuron differentiation GO:0030182 368 0.013
reproductive system development GO:0061458 128 0.013
epithelial cell proliferation GO:0050673 54 0.013
regulation of secretion GO:0051046 224 0.013
cellular protein localization GO:0034613 122 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
metal ion transport GO:0030001 289 0.012
chemical homeostasis GO:0048878 292 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
growth GO:0040007 165 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
spermatogenesis GO:0007283 99 0.012
response to dexamethasone GO:0071548 49 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of cell growth GO:0001558 85 0.012
regulation of protein maturation GO:1903317 50 0.012
folic acid containing compound metabolic process GO:0006760 10 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of signal transduction GO:0009966 318 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
dna metabolic process GO:0006259 96 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
regulation of protein localization GO:0032880 81 0.012
regulation of system process GO:0044057 208 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of blood vessel size GO:0050880 89 0.012
protein complex assembly GO:0006461 263 0.012
glial cell differentiation GO:0010001 65 0.012
calcitriol biosynthetic process from calciol GO:0036378 2 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
regulation of proteolysis GO:0030162 66 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
dendrite morphogenesis GO:0048813 43 0.012
cellular response to metal ion GO:0071248 55 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
transmission of nerve impulse GO:0019226 42 0.012
brain development GO:0007420 247 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
blood circulation GO:0008015 183 0.012
regulation of vasoconstriction GO:0019229 44 0.011
lipid localization GO:0010876 62 0.011
single organism cellular localization GO:1902580 102 0.011
amine metabolic process GO:0009308 38 0.011
fluorene metabolic process GO:0018917 1 0.011
Rat
male sex differentiation GO:0046661 64 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
response to ddt GO:0046680 1 0.011
response to alkaloid GO:0043279 132 0.011
gonad development GO:0008406 104 0.011
cellular amine metabolic process GO:0044106 38 0.011
endothelial cell apoptotic process GO:0072577 3 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
response to wounding GO:0009611 254 0.011
carbohydrate metabolic process GO:0005975 130 0.011
dicarboxylic acid transport GO:0006835 34 0.011
regulation of blood circulation GO:1903522 110 0.011
organelle organization GO:0006996 266 0.011
epithelium development GO:0060429 96 0.011
regulation of catabolic process GO:0009894 113 0.011
protein targeting GO:0006605 61 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
intracellular transport GO:0046907 185 0.011
response to mechanical stimulus GO:0009612 134 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
hormone metabolic process GO:0042445 69 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
purine nucleoside monophosphate catabolic process GO:0009128 55 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
response to camp GO:0051591 91 0.011
calcium ion transport GO:0006816 131 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
cell migration GO:0016477 197 0.010
tetrahydrofolate metabolic process GO:0046653 9 0.010
cofactor metabolic process GO:0051186 95 0.010
regulation of leukocyte differentiation GO:1902105 20 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
muscle cell differentiation GO:0042692 52 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.010
cellular response to ketone GO:1901655 51 0.010
coenzyme metabolic process GO:0006732 86 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
atp metabolic process GO:0046034 72 0.010
cellular protein complex assembly GO:0043623 44 0.010
regulation of phosphate metabolic process GO:0019220 349 0.010
organic anion transport GO:0015711 132 0.010
circulatory system process GO:0003013 183 0.010
cell type specific apoptotic process GO:0097285 134 0.010
positive regulation of biosynthetic process GO:0009891 319 0.010
male gamete generation GO:0048232 99 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
dicarboxylic acid metabolic process GO:0043648 42 0.010

Cyp4a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.017
disease of metabolism DOID:0014667 0 0.011