Rattus norvegicus

105 known processes

Cdkl3

cyclin-dependent kinase-like 3

(Aliases: Nkiatreb,Nkiatre)

Cdkl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.065
cation transmembrane transport GO:0098655 263 0.062
cellular chemical homeostasis GO:0055082 247 0.057
regulation of membrane potential GO:0042391 110 0.050
ion transmembrane transport GO:0034220 365 0.050
regulation of cellular localization GO:0060341 263 0.046
cell cell signaling GO:0007267 335 0.046
cation transport GO:0006812 382 0.045
secretion by cell GO:0032940 248 0.044
regulation of multicellular organismal development GO:2000026 376 0.043
inorganic ion transmembrane transport GO:0098660 229 0.040
inorganic cation transmembrane transport GO:0098662 202 0.039
purine ribonucleotide metabolic process GO:0009150 227 0.037
cellular amine metabolic process GO:0044106 38 0.037
metal ion transport GO:0030001 289 0.036
potassium ion transport GO:0006813 97 0.036
ion homeostasis GO:0050801 212 0.036
sodium ion transport GO:0006814 82 0.035
synaptic growth at neuromuscular junction GO:0051124 1 0.035
reproductive process GO:0022414 372 0.035
dendrite development GO:0016358 72 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
cellular homeostasis GO:0019725 252 0.033
cell morphogenesis GO:0000902 142 0.033
macromolecule localization GO:0033036 252 0.032
divalent inorganic cation homeostasis GO:0072507 165 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
rhythmic process GO:0048511 156 0.032
central nervous system development GO:0007417 311 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
monovalent inorganic cation transport GO:0015672 172 0.032
regulation of hormone levels GO:0010817 187 0.032
secretion GO:0046903 307 0.031
carboxylic acid metabolic process GO:0019752 289 0.030
blood circulation GO:0008015 183 0.030
intracellular signal transduction GO:0035556 314 0.029
growth GO:0040007 165 0.029
negative regulation of signaling GO:0023057 157 0.029
nucleoside phosphate biosynthetic process GO:1901293 102 0.029
chemical homeostasis GO:0048878 292 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
organic substance catabolic process GO:1901575 316 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.028
amine metabolic process GO:0009308 38 0.027
apoptotic process GO:0006915 381 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
synaptic transmission GO:0007268 235 0.027
macromolecular complex assembly GO:0065003 273 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
regulation of ion transport GO:0043269 245 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
organophosphate metabolic process GO:0019637 370 0.026
regulation of phosphate metabolic process GO:0019220 349 0.025
organonitrogen compound catabolic process GO:1901565 179 0.025
oxidation reduction process GO:0055114 304 0.025
rna metabolic process GO:0016070 406 0.025
head development GO:0060322 247 0.025
negative regulation of gene expression GO:0010629 199 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
nucleotide metabolic process GO:0009117 279 0.024
negative regulation of metabolic process GO:0009892 331 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
regulation of synaptic transmission GO:0050804 141 0.024
cellular response to stress GO:0033554 269 0.024
regulation of synaptic plasticity GO:0048167 70 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
multicellular organism growth GO:0035264 1 0.023
cation homeostasis GO:0055080 195 0.023
cellular component assembly GO:0022607 360 0.023
protein complex assembly GO:0006461 263 0.023
cellular component biogenesis GO:0044085 368 0.023
response to ammonium ion GO:0060359 71 0.023
organic acid metabolic process GO:0006082 292 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
peptide hormone secretion GO:0030072 84 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of apoptotic process GO:0042981 335 0.022
protein heterooligomerization GO:0051291 89 0.022
defense response GO:0006952 194 0.022
negative regulation of transport GO:0051051 136 0.022
response to external biotic stimulus GO:0043207 221 0.022
regulation of nervous system development GO:0051960 264 0.022
negative regulation of cell communication GO:0010648 158 0.022
metal ion homeostasis GO:0055065 186 0.021
catabolic process GO:0009056 351 0.021
protein localization to membrane GO:0072657 36 0.021
regulation of cellular component organization GO:0051128 368 0.021
positive regulation of developmental process GO:0051094 283 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
macromolecule catabolic process GO:0009057 58 0.021
cell projection morphogenesis GO:0048858 123 0.021
organophosphate catabolic process GO:0046434 148 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.020
peptide transport GO:0015833 97 0.020
regulation of transmembrane transport GO:0034762 122 0.020
regulation of programmed cell death GO:0043067 341 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
heterocycle catabolic process GO:0046700 167 0.020
positive regulation of gene expression GO:0010628 244 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
single organism reproductive process GO:0044702 297 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cell part morphogenesis GO:0032990 123 0.020
ras protein signal transduction GO:0007265 29 0.020
regulation of signal transduction GO:0009966 318 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
cell projection organization GO:0030030 302 0.019
neuron development GO:0048666 286 0.019
axis specification GO:0009798 4 0.019
oxoacid metabolic process GO:0043436 290 0.019
regulation of hydrolase activity GO:0051336 143 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
reactive nitrogen species metabolic process GO:2001057 1 0.018
response to toxic substance GO:0009636 133 0.018
regulation of rna metabolic process GO:0051252 391 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
cellular ketone metabolic process GO:0042180 51 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
nucleic acid templated transcription GO:0097659 379 0.018
positive regulation of molecular function GO:0044093 230 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
striated muscle contraction GO:0006941 44 0.018
calcium ion transmembrane transport GO:0070588 70 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
developmental growth GO:0048589 100 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
regulation of phosphorylation GO:0042325 248 0.017
regulation of transcription dna templated GO:0006355 374 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
programmed cell death GO:0012501 392 0.017
vesicle mediated transport GO:0016192 181 0.017
development of primary sexual characteristics GO:0045137 107 0.017
regulation of ion transmembrane transport GO:0034765 121 0.017
aromatic compound catabolic process GO:0019439 168 0.017
homeostatic process GO:0042592 331 0.017
negative regulation of ion transport GO:0043271 51 0.017
rna biosynthetic process GO:0032774 380 0.017
cellular cation homeostasis GO:0030003 180 0.017
regulation of neuron differentiation GO:0045664 208 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
organelle organization GO:0006996 266 0.017
cellular ion homeostasis GO:0006873 184 0.016
single organism biosynthetic process GO:0044711 342 0.016
central nervous system neuron differentiation GO:0021953 17 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
response to ketone GO:1901654 182 0.016
purine containing compound metabolic process GO:0072521 253 0.016
gastrulation GO:0007369 2 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
intracellular transport GO:0046907 185 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
protein complex biogenesis GO:0070271 263 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
response to inorganic substance GO:0010035 377 0.016
response to ethanol GO:0045471 162 0.016
transcription dna templated GO:0006351 377 0.016
heart contraction GO:0060047 57 0.016
carboxylic acid transport GO:0046942 115 0.016
synapse organization GO:0050808 46 0.016
proteolysis GO:0006508 175 0.016
response to glucocorticoid GO:0051384 223 0.016
regulation of cell projection organization GO:0031344 175 0.016
signal release GO:0023061 145 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
single organism catabolic process GO:0044712 283 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
adult locomotory behavior GO:0008344 4 0.015
regulation of secretion by cell GO:1903530 208 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
muscle cell proliferation GO:0033002 84 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
single organism membrane organization GO:0044802 74 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
response to growth factor GO:0070848 189 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
peptide secretion GO:0002790 86 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
neuromuscular process GO:0050905 2 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
organ formation GO:0048645 3 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
positive regulation of signaling GO:0023056 270 0.015
positive regulation of cell death GO:0010942 184 0.015
aging GO:0007568 241 0.015
protein phosphorylation GO:0006468 345 0.014
cellular catabolic process GO:0044248 295 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
regulation of molecular function GO:0065009 398 0.014
regulation of peptide secretion GO:0002791 82 0.014
nitrogen compound transport GO:0071705 229 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
neuron projection development GO:0031175 273 0.014
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.014
regulation of transporter activity GO:0032409 50 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
neuron neuron synaptic transmission GO:0007270 60 0.014
gliogenesis GO:0042063 93 0.014
positive regulation of cell communication GO:0010647 271 0.014
regulation of catabolic process GO:0009894 113 0.014
brain development GO:0007420 247 0.013
tissue development GO:0009888 252 0.013
multicellular organism reproduction GO:0032504 233 0.013
response to hexose GO:0009746 144 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
cellular component morphogenesis GO:0032989 155 0.013
calcium ion homeostasis GO:0055074 162 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
response to glucose GO:0009749 136 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
heart process GO:0003015 57 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
generation of precursor metabolites and energy GO:0006091 62 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
positive regulation of cell development GO:0010720 176 0.012
regulation of peptide transport GO:0090087 87 0.012
cellular component movement GO:0006928 248 0.012
neural crest cell development GO:0014032 2 0.012
response to metal ion GO:0010038 253 0.012
hormone transport GO:0009914 121 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
multi organism reproductive process GO:0044703 262 0.012
regulation of cell development GO:0060284 263 0.012
protein oligomerization GO:0051259 191 0.012
sensory perception GO:0007600 101 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
camera type eye morphogenesis GO:0048593 2 0.012
potassium ion transmembrane transport GO:0071805 71 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of growth GO:0040008 105 0.012
positive regulation of transport GO:0051050 245 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
negative regulation of hormone secretion GO:0046888 46 0.012
inflammatory response GO:0006954 150 0.012
amide transport GO:0042886 105 0.012
neurotransmitter secretion GO:0007269 33 0.012
nucleotide catabolic process GO:0009166 139 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
forebrain development GO:0030900 98 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to hypoxia GO:0001666 231 0.011
hormone secretion GO:0046879 115 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
divalent metal ion transport GO:0070838 132 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
cell fate determination GO:0001709 2 0.011
organic hydroxy compound transport GO:0015850 77 0.011
jak stat cascade GO:0007259 26 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
eye morphogenesis GO:0048592 4 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
sequestering of calcium ion GO:0051208 8 0.011
regulation of mapk cascade GO:0043408 116 0.011
striated muscle tissue development GO:0014706 58 0.011
response to purine containing compound GO:0014074 126 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of secretion GO:0051046 224 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
protein complex subunit organization GO:0071822 302 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
regulation of heart rate GO:0002027 16 0.011
reproduction GO:0000003 245 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
neural crest cell differentiation GO:0014033 2 0.011
spindle organization GO:0007051 2 0.011
regulation of homeostatic process GO:0032844 101 0.011
circulatory system process GO:0003013 183 0.011
negative regulation of cell death GO:0060548 229 0.011
regulation of hormone secretion GO:0046883 106 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
organic anion transport GO:0015711 132 0.011
intracellular protein transport GO:0006886 79 0.011
lipid storage GO:0019915 1 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
regulation of protein metabolic process GO:0051246 289 0.010
rho protein signal transduction GO:0007266 11 0.010
peptidyl amino acid modification GO:0018193 126 0.010
cytoplasmic transport GO:0016482 115 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
regulation of catalytic activity GO:0050790 304 0.010
male gamete generation GO:0048232 99 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
response to reactive oxygen species GO:0000302 120 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
neuron differentiation GO:0030182 368 0.010
single fertilization GO:0007338 3 0.010
regulation of ion transmembrane transporter activity GO:0032412 48 0.010
startle response GO:0001964 2 0.010
response to cytokine GO:0034097 215 0.010

Cdkl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
central nervous system disease DOID:331 0 0.021
brain disease DOID:936 0 0.016
neuromuscular disease DOID:440 0 0.014
neuropathy DOID:870 0 0.014
sensory system disease DOID:0050155 0 0.013
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
eye and adnexa disease DOID:1492 0 0.011
musculoskeletal system disease DOID:17 0 0.010