Rattus norvegicus

14 known processes

Prss21

protease, serine, 21

(Aliases: Resp-1,Esp-1)

Prss21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to organic cyclic compound GO:0071407 202 0.162
growth GO:0040007 165 0.134
positive regulation of cell proliferation GO:0008284 249 0.134
muscle contraction GO:0006936 88 0.121
response to wounding GO:0009611 254 0.113
secretion GO:0046903 307 0.098
positive regulation of developmental process GO:0051094 283 0.093
response to nutrient levels GO:0031667 370 0.091
regulation of behavior GO:0050795 61 0.086
angiogenesis GO:0001525 53 0.083
macromolecule localization GO:0033036 252 0.083
negative regulation of luteinizing hormone secretion GO:0033685 4 0.081
developmental growth GO:0048589 100 0.077
cellular response to endogenous stimulus GO:0071495 377 0.075
multicellular organism reproduction GO:0032504 233 0.073
cell activation GO:0001775 97 0.070
regulation of amine transport GO:0051952 54 0.069
response to external biotic stimulus GO:0043207 221 0.069
cell motility GO:0048870 202 0.068
response to decreased oxygen levels GO:0036293 237 0.063
brain development GO:0007420 247 0.061
negative regulation of neuron differentiation GO:0045665 62 0.061
regulation of cell proliferation GO:0042127 359 0.060
synaptic transmission GO:0007268 235 0.059
response to molecule of bacterial origin GO:0002237 194 0.057
response to extracellular stimulus GO:0009991 380 0.053
defense response GO:0006952 194 0.053
neuron death GO:0070997 127 0.053
negative regulation of apoptotic process GO:0043066 181 0.053
secretion by cell GO:0032940 248 0.051
negative regulation of amine transport GO:0051953 24 0.049
positive regulation of locomotion GO:0040017 102 0.048
negative regulation of cell development GO:0010721 82 0.047
regulation of immune response GO:0050776 55 0.047
regulation of cell development GO:0060284 263 0.046
protein complex subunit organization GO:0071822 302 0.046
sodium ion transport GO:0006814 82 0.046
cellular ion homeostasis GO:0006873 184 0.045
positive regulation of synaptic transmission GO:0050806 62 0.045
neurological system process GO:0050877 219 0.044
negative regulation of neurogenesis GO:0050768 78 0.044
cellular chemical homeostasis GO:0055082 247 0.044
positive regulation of nervous system development GO:0051962 178 0.044
macromolecular complex subunit organization GO:0043933 339 0.042
immune response GO:0006955 104 0.042
cytokine production GO:0001816 61 0.042
negative regulation of multicellular organismal process GO:0051241 203 0.041
negative regulation of programmed cell death GO:0043069 183 0.041
single organism reproductive process GO:0044702 297 0.041
cellular amine metabolic process GO:0044106 38 0.040
cation homeostasis GO:0055080 195 0.040
apoptotic process GO:0006915 381 0.040
positive regulation of signaling GO:0023056 270 0.040
cellular cation homeostasis GO:0030003 180 0.039
regulation of endocrine process GO:0044060 21 0.039
regulation of immune system process GO:0002682 123 0.038
calcium ion homeostasis GO:0055074 162 0.038
rna metabolic process GO:0016070 406 0.038
regulation of nervous system development GO:0051960 264 0.037
regulation of cell differentiation GO:0045595 320 0.037
head development GO:0060322 247 0.037
immune system process GO:0002376 204 0.036
positive regulation of cell differentiation GO:0045597 217 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.035
regulation of response to external stimulus GO:0032101 106 0.035
transmembrane transport GO:0055085 412 0.035
negative regulation of metabolic process GO:0009892 331 0.035
positive regulation of cell communication GO:0010647 271 0.035
regulation of hormone levels GO:0010817 187 0.034
regulation of secretion GO:0051046 224 0.034
ion transmembrane transport GO:0034220 365 0.034
organic acid transport GO:0015849 116 0.034
regulation of phosphorylation GO:0042325 248 0.034
organelle organization GO:0006996 266 0.034
cation transport GO:0006812 382 0.034
regulation of signal transduction GO:0009966 318 0.033
hormone transport GO:0009914 121 0.033
positive regulation of neurogenesis GO:0050769 165 0.032
amine transport GO:0015837 57 0.032
amine metabolic process GO:0009308 38 0.032
reproduction GO:0000003 245 0.031
sexual reproduction GO:0019953 148 0.031
leukocyte activation GO:0045321 76 0.031
response to oxidative stress GO:0006979 186 0.031
response to growth factor GO:0070848 189 0.031
organonitrogen compound biosynthetic process GO:1901566 167 0.031
inflammatory response to antigenic stimulus GO:0002437 18 0.030
metal ion homeostasis GO:0055065 186 0.030
circulatory system development GO:0072359 134 0.030
regulation of synaptic transmission GO:0050804 141 0.030
anatomical structure formation involved in morphogenesis GO:0048646 83 0.030
cytosolic calcium ion homeostasis GO:0051480 140 0.030
oxoacid metabolic process GO:0043436 290 0.029
central nervous system development GO:0007417 311 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
blood vessel morphogenesis GO:0048514 58 0.028
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
regulation of angiogenesis GO:0045765 39 0.028
neutrophil apoptotic process GO:0001781 4 0.028
regulation of programmed cell death GO:0043067 341 0.028
negative regulation of cell communication GO:0010648 158 0.028
positive regulation of immune system process GO:0002684 90 0.028
cellular component biogenesis GO:0044085 368 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
monocarboxylic acid transport GO:0015718 52 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
eye morphogenesis GO:0048592 4 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
response to other organism GO:0051707 220 0.027
chemical homeostasis GO:0048878 292 0.027
negative regulation of chronic inflammatory response GO:0002677 2 0.027
programmed cell death GO:0012501 392 0.027
regulation of cell migration GO:0030334 128 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
positive regulation of cell development GO:0010720 176 0.026
reproductive process GO:0022414 372 0.026
macromolecular complex assembly GO:0065003 273 0.026
positive regulation of transferase activity GO:0051347 81 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
protein phosphorylation GO:0006468 345 0.026
homeostatic process GO:0042592 331 0.026
regulation of cellular component organization GO:0051128 368 0.026
cellular component assembly GO:0022607 360 0.026
regulation of growth GO:0040008 105 0.026
regulation of cell cycle GO:0051726 73 0.026
carboxylic acid transport GO:0046942 115 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
detection of stimulus GO:0051606 24 0.025
intracellular signal transduction GO:0035556 314 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
response to purine containing compound GO:0014074 126 0.024
positive regulation of homeostatic process GO:0032846 49 0.024
positive regulation of leukocyte migration GO:0002687 21 0.024
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.024
positive regulation of rna metabolic process GO:0051254 203 0.023
endocrine process GO:0050886 32 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of apoptotic process GO:0042981 335 0.023
protein localization GO:0008104 191 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
cell cell signaling GO:0007267 335 0.023
response to hypoxia GO:0001666 231 0.023
neuron development GO:0048666 286 0.023
negative regulation of secretion by cell GO:1903531 72 0.022
positive regulation of kinase activity GO:0033674 77 0.022
multi organism reproductive process GO:0044703 262 0.022
vesicle mediated transport GO:0016192 181 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
response to cocaine GO:0042220 39 0.022
positive regulation of cellular component movement GO:0051272 102 0.021
response to inorganic substance GO:0010035 377 0.021
regulation of molecular function GO:0065009 398 0.021
cellular ketone metabolic process GO:0042180 51 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
negative regulation of nervous system development GO:0051961 79 0.021
negative regulation of cell death GO:0060548 229 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
response to organophosphorus GO:0046683 102 0.021
response to toxic substance GO:0009636 133 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
urinary bladder smooth muscle contraction GO:0014832 4 0.020
organic acid metabolic process GO:0006082 292 0.020
muscle system process GO:0003012 115 0.020
development of primary sexual characteristics GO:0045137 107 0.020
regulation of ossification GO:0030278 32 0.020
response to oxygen levels GO:0070482 265 0.020
cellular response to stress GO:0033554 269 0.020
regulation of synaptic transmission glutamatergic GO:0051966 26 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
lipid localization GO:0010876 62 0.019
cardiovascular system development GO:0072358 134 0.019
positive regulation of protein modification process GO:0031401 142 0.019
localization of cell GO:0051674 202 0.019
sex differentiation GO:0007548 113 0.019
regulation of homeostatic process GO:0032844 101 0.019
response to biotic stimulus GO:0009607 226 0.019
spermatogenesis GO:0007283 99 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
sensory perception GO:0007600 101 0.019
regulation of neuron apoptotic process GO:0043523 83 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
transcription dna templated GO:0006351 377 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
regulation of anion transport GO:0044070 43 0.017
ion homeostasis GO:0050801 212 0.017
regulation of vasculature development GO:1901342 44 0.017
cell growth GO:0016049 104 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
response to ethanol GO:0045471 162 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
cell cycle GO:0007049 101 0.017
positive regulation of cell migration GO:0030335 96 0.017
action potential GO:0001508 54 0.017
regulation of chemotaxis GO:0050920 29 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
negative regulation of gene expression GO:0010629 199 0.017
regulation of organic acid transport GO:0032890 35 0.017
vasculature development GO:0001944 70 0.017
gamete generation GO:0007276 124 0.017
positive regulation of blood pressure GO:0045777 31 0.017
protein complex assembly GO:0006461 263 0.017
negative regulation of response to external stimulus GO:0032102 37 0.016
hormone secretion GO:0046879 115 0.016
protein transport GO:0015031 132 0.016
regulation of kinase activity GO:0043549 117 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
male gamete generation GO:0048232 99 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
negative regulation of developmental process GO:0051093 125 0.016
regulation of secretion by cell GO:1903530 208 0.016
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.016
negative regulation of signaling GO:0023057 157 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
regulation of protein modification process GO:0031399 194 0.016
regulation of defense response GO:0031347 68 0.015
negative regulation of ion transport GO:0043271 51 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
gonad development GO:0008406 104 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of ion transport GO:0043269 245 0.015
response to cytokine GO:0034097 215 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
regulation of hormone secretion GO:0046883 106 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
response to alkaloid GO:0043279 132 0.015
multicellular organism growth GO:0035264 1 0.015
amide transport GO:0042886 105 0.015
single organism biosynthetic process GO:0044711 342 0.015
regulation of neurogenesis GO:0050767 247 0.015
regulation of excretion GO:0044062 21 0.014
gastric motility GO:0035482 3 0.014
blood vessel development GO:0001568 69 0.014
response to estradiol GO:0032355 164 0.014
regulation of cellular localization GO:0060341 263 0.014
neuron neuron synaptic transmission GO:0007270 60 0.014
circadian rhythm GO:0007623 88 0.014
monoamine transport GO:0015844 43 0.014
response to mechanical stimulus GO:0009612 134 0.014
urinary tract smooth muscle contraction GO:0014848 4 0.014
peptide transport GO:0015833 97 0.014
positive regulation of serotonin secretion GO:0014064 1 0.014
signal release GO:0023061 145 0.014
organic anion transport GO:0015711 132 0.014
regulation of rna metabolic process GO:0051252 391 0.014
regulation of neuron death GO:1901214 115 0.014
cell projection organization GO:0030030 302 0.013
sensory perception of bitter taste GO:0050913 4 0.013
response to ammonium ion GO:0060359 71 0.013
regulation of transcription dna templated GO:0006355 374 0.013
cellular response to lipid GO:0071396 201 0.013
multicellular organismal response to stress GO:0033555 25 0.013
regulation of protein transport GO:0051223 68 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
response to nutrient GO:0007584 248 0.013
positive regulation of secretion GO:0051047 140 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
limb morphogenesis GO:0035108 4 0.013
osteoblast differentiation GO:0001649 26 0.013
sequestering of calcium ion GO:0051208 8 0.013
endocrine hormone secretion GO:0060986 21 0.013
response to cgmp GO:0070305 3 0.013
negative regulation of transport GO:0051051 136 0.013
protein oligomerization GO:0051259 191 0.013
response to amine GO:0014075 46 0.013
single organism intracellular transport GO:1902582 166 0.013
reproductive system development GO:0061458 128 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of cell motility GO:2000145 131 0.013
single organism organelle organization GO:1902589 180 0.013
sodium ion transmembrane transport GO:0035725 67 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
inflammatory response GO:0006954 150 0.012
neuron projection development GO:0031175 273 0.012
neuron apoptotic process GO:0051402 88 0.012
regulation of catalytic activity GO:0050790 304 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of protein metabolic process GO:0051246 289 0.012
receptor mediated endocytosis GO:0006898 42 0.012
cell cycle process GO:0022402 57 0.012
regeneration GO:0031099 163 0.012
feeding behavior GO:0007631 53 0.012
inflammatory cell apoptotic process GO:0006925 5 0.012
aging GO:0007568 241 0.012
ras protein signal transduction GO:0007265 29 0.012
regulation of neuron differentiation GO:0045664 208 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
lipid biosynthetic process GO:0008610 128 0.011
regulation of transferase activity GO:0051338 123 0.011
female gonad development GO:0008585 53 0.011
detection of stimulus involved in sensory perception GO:0050906 16 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
response to reactive oxygen species GO:0000302 120 0.011
response to radiation GO:0009314 137 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of response to stress GO:0080134 126 0.011
negative regulation of secretion GO:0051048 82 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
cell type specific apoptotic process GO:0097285 134 0.011
proteolysis GO:0006508 175 0.011
developmental process involved in reproduction GO:0003006 159 0.011
myeloid leukocyte activation GO:0002274 36 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
positive regulation of cytokine production GO:0001819 42 0.011
second messenger mediated signaling GO:0019932 51 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
response to lipopolysaccharide GO:0032496 191 0.011
protein complex biogenesis GO:0070271 263 0.011
regulation of membrane potential GO:0042391 110 0.010
fatty acid transport GO:0015908 25 0.010
peptide secretion GO:0002790 86 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
cellular component movement GO:0006928 248 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
divalent inorganic cation transport GO:0072511 134 0.010
response to camp GO:0051591 91 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
regulation of ion homeostasis GO:2000021 63 0.010
nitrogen compound transport GO:0071705 229 0.010

Prss21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019