Rattus norvegicus

88 known processes

Serpina1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

(Aliases: AAT,Pi,Spi1)

Serpina1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.837
response to inorganic substance GO:0010035 377 0.762
renin angiotensin regulation of aldosterone production GO:0002018 3 0.701
Rat
response to peptide GO:1901652 292 0.677
Mouse Rat
response to lipopolysaccharide GO:0032496 191 0.675
cellular response to hormone stimulus GO:0032870 247 0.611
Rat
positive regulation of extracellular matrix organization GO:1903055 4 0.579
Rat
liver development GO:0001889 90 0.558
response to platinum ion GO:0070541 4 0.502
positive regulation of blood coagulation GO:0030194 4 0.484
regeneration GO:0031099 163 0.482
response to estradiol GO:0032355 164 0.475
positive regulation of coagulation GO:0050820 5 0.462
extracellular matrix constituent secretion GO:0070278 4 0.452
Rat
response to nutrient levels GO:0031667 370 0.444
Rat
response to methanol GO:0033986 1 0.443
fibrinolysis GO:0042730 2 0.413
regulation of fibrinolysis GO:0051917 2 0.413
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.401
Rat
response to purine containing compound GO:0014074 126 0.393
Rat
response to vitamin b6 GO:0034516 1 0.372
Rat
response to lead ion GO:0010288 33 0.366
regulation of hemostasis GO:1900046 9 0.363
immune system process GO:0002376 204 0.344
Rat
organ regeneration GO:0031100 101 0.342
proteolysis GO:0006508 175 0.333
blood coagulation GO:0007596 26 0.321
cellular response to organic cyclic compound GO:0071407 202 0.318
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.316
Rat
response to extracellular stimulus GO:0009991 380 0.313
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.312
response to estrogen GO:0043627 232 0.303
cellular response to nitrogen compound GO:1901699 210 0.270
Rat
response to oxygen levels GO:0070482 265 0.270
response to peptide hormone GO:0043434 278 0.259
Mouse Rat
regulation of body fluid levels GO:0050878 90 0.258
reproductive process GO:0022414 372 0.249
Rat
regulation of extracellular matrix constituent secretion GO:0003330 2 0.249
Rat
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.243
Rat
coagulation GO:0050817 28 0.236
regulation of programmed cell death GO:0043067 341 0.235
Rat
response to acid chemical GO:0001101 222 0.231
response to transition metal nanoparticle GO:1990267 122 0.218
response to mechanical stimulus GO:0009612 134 0.214
Rat
response to mineralocorticoid GO:0051385 49 0.212
Rat
plasminogen activation GO:0031639 2 0.209
behavior GO:0007610 205 0.203
Rat
cellular homeostasis GO:0019725 252 0.202
Rat
response to camp GO:0051591 91 0.194
Rat
multicellular organism reproduction GO:0032504 233 0.185
wound healing GO:0042060 122 0.172
response to wounding GO:0009611 254 0.170
urea cycle GO:0000050 5 0.168
regulation of system process GO:0044057 208 0.167
Rat
inflammatory response GO:0006954 150 0.164
response to hypoxia GO:0001666 231 0.163
multi multicellular organism process GO:0044706 138 0.162
Rat
regulation of tube size GO:0035150 89 0.158
Rat
regulation of coagulation GO:0050818 11 0.156
alkaloid metabolic process GO:0009820 3 0.154
organic acid metabolic process GO:0006082 292 0.151
positive regulation of multicellular organismal process GO:0051240 387 0.148
Rat
regulation of multicellular organismal development GO:2000026 376 0.148
Rat
cellular response to glucocorticoid stimulus GO:0071385 68 0.147
Rat
negative regulation of endothelial cell proliferation GO:0001937 5 0.144
Rat
regulation of blood pressure GO:0008217 83 0.142
Rat
regulation of wound healing GO:0061041 14 0.140
regulation of serine type peptidase activity GO:1902571 1 0.139
regulation of apoptotic process GO:0042981 335 0.138
Rat
blood circulation GO:0008015 183 0.136
Rat
cellular response to organonitrogen compound GO:0071417 197 0.132
Rat
response to insulin GO:0032868 133 0.131
circulatory system development GO:0072359 134 0.121
Rat
hepaticobiliary system development GO:0061008 90 0.120
cellular response to insulin stimulus GO:0032869 81 0.118
cellular amide metabolic process GO:0043603 44 0.116
cellular response to oxygen containing compound GO:1901701 386 0.115
Rat
multi organism reproductive process GO:0044703 262 0.114
Rat
response to cytokine GO:0034097 215 0.112
positive regulation of circadian sleep wake cycle sleep GO:0045938 9 0.108
regulation of endothelial cell apoptotic process GO:2000351 3 0.105
oxoacid metabolic process GO:0043436 290 0.105
apoptotic process GO:0006915 381 0.104
Rat
response to corticosteroid GO:0031960 235 0.102
Rat
response to ketone GO:1901654 182 0.101
Rat
response to carbohydrate GO:0009743 183 0.099
response to bacterium GO:0009617 200 0.099
negative regulation of fibrinolysis GO:0051918 2 0.098
regulation of secretion GO:0051046 224 0.097
Rat
response to vitamin GO:0033273 131 0.095
Rat
response to hexose GO:0009746 144 0.094
negative regulation of biomineral tissue development GO:0070168 2 0.092
response to decreased oxygen levels GO:0036293 237 0.092
vascular process in circulatory system GO:0003018 96 0.088
Rat
cellular sodium ion homeostasis GO:0006883 4 0.085
Rat
cellular response to growth factor stimulus GO:0071363 162 0.084
negative regulation of endopeptidase activity GO:0010951 36 0.082
cellular lipid metabolic process GO:0044255 208 0.081
female pregnancy GO:0007565 122 0.081
Rat
response to organophosphorus GO:0046683 102 0.080
Rat
regulation of catalytic activity GO:0050790 304 0.079
cellular response to interferon gamma GO:0071346 14 0.079
Rat
regulation of amine transport GO:0051952 54 0.078
Rat
regulation of angiogenesis GO:0045765 39 0.078
Rat
regulation of vasculature development GO:1901342 44 0.077
Rat
pyridine containing compound metabolic process GO:0072524 32 0.076
amine metabolic process GO:0009308 38 0.075
response to glucocorticoid GO:0051384 223 0.074
Rat
response to amino acid GO:0043200 75 0.074
response to other organism GO:0051707 220 0.074
regulation of mapk cascade GO:0043408 116 0.074
gland development GO:0048732 155 0.073
positive regulation of blood circulation GO:1903524 65 0.072
Rat
cellular catabolic process GO:0044248 295 0.071
homeostatic process GO:0042592 331 0.069
Rat
carboxylic acid metabolic process GO:0019752 289 0.067
negative regulation of multicellular organismal process GO:0051241 203 0.065
Rat
response to zinc ion GO:0010043 39 0.065
aromatic amino acid family metabolic process GO:0009072 9 0.063
cellular response to alcohol GO:0097306 87 0.063
single organism behavior GO:0044708 130 0.062
tonic smooth muscle contraction GO:0014820 4 0.060
Rat
response to nutrient GO:0007584 248 0.060
Rat
response to fatty acid GO:0070542 65 0.060
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.060
Rat
response to nicotine GO:0035094 51 0.059
negative regulation of cellular metabolic process GO:0031324 281 0.059
heterotypic cell cell adhesion GO:0034113 2 0.058
single organism reproductive process GO:0044702 297 0.058
intracellular signal transduction GO:0035556 314 0.057
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.056
secretion GO:0046903 307 0.056
Rat
cellular response to endogenous stimulus GO:0071495 377 0.055
Rat
ion homeostasis GO:0050801 212 0.055
Rat
regulation of renal sodium excretion GO:0035813 20 0.055
Rat
regulation of immunoglobulin production GO:0002637 4 0.055
immune response GO:0006955 104 0.054
Rat
unsaturated fatty acid metabolic process GO:0033559 39 0.054
regulation of cellular protein metabolic process GO:0032268 267 0.054
aromatic amino acid family catabolic process GO:0009074 7 0.054
organic substance catabolic process GO:1901575 316 0.053
regulation of blood circulation GO:1903522 110 0.053
Rat
circulatory system process GO:0003013 183 0.051
Rat
negative regulation of molecular function GO:0044092 133 0.051
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.051
circadian sleep wake cycle non rem sleep GO:0042748 8 0.051
reproduction GO:0000003 245 0.050
metal ion homeostasis GO:0055065 186 0.050
Rat
positive regulation of response to stimulus GO:0048584 285 0.049
lipid transport GO:0006869 61 0.049
regulation of hydrolase activity GO:0051336 143 0.048
dopamine metabolic process GO:0042417 12 0.048
aging GO:0007568 241 0.048
Rat
nitrogen cycle metabolic process GO:0071941 5 0.048
response to triglyceride GO:0034014 3 0.048
regulation of behavior GO:0050795 61 0.047
brain renin angiotensin system GO:0002035 3 0.047
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.047
Rat
response to calcium ion GO:0051592 59 0.047
protein processing GO:0016485 68 0.046
negative regulation of protein metabolic process GO:0051248 114 0.046
renal sodium excretion GO:0035812 20 0.046
Rat
negative regulation of protein maturation GO:1903318 47 0.046
positive regulation of hemostasis GO:1900048 4 0.046
hemostasis GO:0007599 26 0.046
regulation of cell proliferation GO:0042127 359 0.046
Rat
epoxygenase p450 pathway GO:0019373 1 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.044
transmission of nerve impulse GO:0019226 42 0.044
Rat
long chain fatty acid metabolic process GO:0001676 32 0.044
protein phosphorylation GO:0006468 345 0.044
regulation of secretion by cell GO:1903530 208 0.044
Rat
response to growth factor GO:0070848 189 0.043
multicellular organismal reproductive process GO:0048609 233 0.043
renal system process GO:0003014 40 0.042
Rat
response to mercury ion GO:0046689 15 0.042
urea metabolic process GO:0019627 5 0.041
cellular response to corticosteroid stimulus GO:0071384 69 0.041
Rat
regulation of molecular function GO:0065009 398 0.041
regulation of cell migration GO:0030334 128 0.041
positive regulation of wound healing GO:0090303 6 0.041
cell cell signaling GO:0007267 335 0.041
Rat
cellular ketone metabolic process GO:0042180 51 0.041
response to chromate GO:0046687 3 0.040
response to biotic stimulus GO:0009607 226 0.040
chemical homeostasis GO:0048878 292 0.040
Rat
regulation of endothelial cell proliferation GO:0001936 18 0.040
Rat
immunoglobulin mediated immune response GO:0016064 4 0.039
protein maturation GO:0051604 68 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
nitrogen compound transport GO:0071705 229 0.039
Rat
negative regulation of response to stimulus GO:0048585 155 0.039
endothelial cell apoptotic process GO:0072577 3 0.038
regulation of response to external stimulus GO:0032101 106 0.038
ossification GO:0001503 70 0.038
positive regulation of heterotypic cell cell adhesion GO:0034116 1 0.038
negative regulation of serine type peptidase activity GO:1902572 1 0.037
response to dexamethasone GO:0071548 49 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
gamete generation GO:0007276 124 0.036
negative regulation of peptidase activity GO:0010466 38 0.036
negative regulation of developmental process GO:0051093 125 0.036
Rat
feeding behavior GO:0007631 53 0.036
Rat
protein complex assembly GO:0006461 263 0.036
male sex differentiation GO:0046661 64 0.036
regulation of b cell mediated immunity GO:0002712 2 0.035
response to monosaccharide GO:0034284 159 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
regulation of blood coagulation GO:0030193 9 0.034
erythrocyte differentiation GO:0030218 1 0.034
negative regulation of coagulation GO:0050819 7 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.033
cellular metal ion homeostasis GO:0006875 172 0.033
Rat
cellular amine metabolic process GO:0044106 38 0.033
locomotion GO:0040011 237 0.032
negative regulation of metabolic process GO:0009892 331 0.032
regulation of reactive oxygen species metabolic process GO:2000377 26 0.032
Rat
smooth muscle cell apoptotic process GO:0034390 7 0.031
regulation of transcription dna templated GO:0006355 374 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
organonitrogen compound biosynthetic process GO:1901566 167 0.031
negative regulation of apoptotic process GO:0043066 181 0.030
cation homeostasis GO:0055080 195 0.030
Rat
gonad development GO:0008406 104 0.030
negative regulation of ossification GO:0030279 9 0.030
regulation of protein metabolic process GO:0051246 289 0.030
tissue regeneration GO:0042246 36 0.030
positive regulation of immunoglobulin production GO:0002639 4 0.030
regulation of anatomical structure morphogenesis GO:0022603 141 0.030
Rat
reproductive system development GO:0061458 128 0.029
reactive oxygen species metabolic process GO:0072593 37 0.029
Rat
lipid localization GO:0010876 62 0.029
regulation of protein processing GO:0070613 50 0.029
defense response GO:0006952 194 0.029
synaptic transmission GO:0007268 235 0.029
Rat
macromolecule localization GO:0033036 252 0.029
Rat
response to cesium ion GO:0010164 2 0.029
arachidonic acid metabolic process GO:0019369 20 0.029
negative regulation of cell death GO:0060548 229 0.028
innate immune response GO:0045087 35 0.028
Rat
protein homotetramerization GO:0051289 25 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
Rat
catabolic process GO:0009056 351 0.028
response to ethanol GO:0045471 162 0.027
regulation of protein maturation GO:1903317 50 0.027
positive regulation of circadian rhythm GO:0042753 11 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
icosanoid metabolic process GO:0006690 38 0.026
multicellular organismal homeostasis GO:0048871 49 0.026
angiogenesis GO:0001525 53 0.026
Rat
hepatocyte proliferation GO:0072574 3 0.026
phenol containing compound biosynthetic process GO:0046189 9 0.026
regulation of immune system process GO:0002682 123 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.026
cellular component biogenesis GO:0044085 368 0.025
regulation of immunoglobulin mediated immune response GO:0002889 2 0.025
response to sulfur dioxide GO:0010477 3 0.025
b cell mediated immunity GO:0019724 4 0.025
sexual reproduction GO:0019953 148 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
positive regulation of response to wounding GO:1903036 34 0.025
cellular response to camp GO:0071320 26 0.025
Rat
regulation of homeostatic process GO:0032844 101 0.024
Rat
mammary gland development GO:0030879 38 0.024
cardiovascular system development GO:0072358 134 0.024
Rat
regulation of phosphorylation GO:0042325 248 0.024
acute inflammatory response GO:0002526 58 0.024
alpha amino acid metabolic process GO:1901605 71 0.024
kidney development GO:0001822 67 0.024
positive regulation of homeostatic process GO:0032846 49 0.024
Rat
developmental process involved in reproduction GO:0003006 159 0.024
tissue development GO:0009888 252 0.024
Rat
response to alkaloid GO:0043279 132 0.024
response to activity GO:0014823 73 0.024
Rat
cellular chemical homeostasis GO:0055082 247 0.024
Rat
renal system development GO:0072001 67 0.023
regulation of heterotypic cell cell adhesion GO:0034114 2 0.023
positive regulation of behavior GO:0048520 38 0.023
oxidation reduction process GO:0055114 304 0.023
triglyceride metabolic process GO:0006641 21 0.023
regulation of anatomical structure size GO:0090066 135 0.023
Rat
cellular modified amino acid metabolic process GO:0006575 61 0.023
regulation of atpase activity GO:0043462 7 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
negative regulation of phosphate metabolic process GO:0045936 80 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
regulation of excretion GO:0044062 21 0.022
Rat
single organism catabolic process GO:0044712 283 0.022
cellular response to gonadotropin stimulus GO:0071371 17 0.022
positive regulation of secretion by cell GO:1903532 128 0.022
Rat
regulation of cellular component movement GO:0051270 150 0.022
halogenated hydrocarbon metabolic process GO:0042197 4 0.022
programmed cell death GO:0012501 392 0.022
Rat
regulation of peptidase activity GO:0052547 55 0.022
sperm egg recognition GO:0035036 1 0.021
cellular component movement GO:0006928 248 0.021
cell motility GO:0048870 202 0.021
regulation of response to wounding GO:1903034 69 0.021
reactive nitrogen species metabolic process GO:2001057 1 0.021
regulation of growth GO:0040008 105 0.021
Rat
regulation of cellular localization GO:0060341 263 0.021
Rat
cellular response to lipid GO:0071396 201 0.021
Rat
cation transport GO:0006812 382 0.021
Rat
spermatogenesis GO:0007283 99 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
alpha amino acid catabolic process GO:1901606 20 0.021
negative regulation of serine type endopeptidase activity GO:1900004 1 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
Mouse
response to external biotic stimulus GO:0043207 221 0.021
platelet aggregation GO:0070527 4 0.021
mapk cascade GO:0000165 140 0.021
Rat
male gonad development GO:0008584 59 0.021
rhythmic process GO:0048511 156 0.021
regulation of cell growth GO:0001558 85 0.020
Rat
response to glucose GO:0009749 136 0.020
neuron development GO:0048666 286 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
circadian rhythm GO:0007623 88 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.020
heart morphogenesis GO:0003007 3 0.020
regulation of circadian sleep wake cycle GO:0042749 18 0.020
negative regulation of humoral immune response GO:0002921 4 0.020
negative regulation of gene expression GO:0010629 199 0.020
response to molecule of bacterial origin GO:0002237 194 0.019
cellular cation homeostasis GO:0030003 180 0.019
Rat
isoquinoline alkaloid metabolic process GO:0033076 2 0.019
positive regulation of immune response GO:0050778 42 0.019
sodium ion homeostasis GO:0055078 23 0.019
Rat
acute phase response GO:0006953 20 0.019
regulation of blood vessel size GO:0050880 89 0.019
Rat
arginine metabolic process GO:0006525 6 0.019
regulation of locomotion GO:0040012 148 0.019
biological adhesion GO:0022610 110 0.019
cell migration GO:0016477 197 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
Rat
vasodilation GO:0042311 44 0.019
Rat
regulation of proteolysis GO:0030162 66 0.019
regulation of ion transport GO:0043269 245 0.018
Rat
angiotensin mediated drinking behavior GO:0003051 2 0.018
Rat
response to starvation GO:0042594 59 0.018
negative regulation of blood vessel morphogenesis GO:2000181 10 0.018
Rat
metal ion transport GO:0030001 289 0.018
Rat
positive regulation of cellular component movement GO:0051272 102 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of cell development GO:0060284 263 0.018
response to interferon gamma GO:0034341 20 0.018
Rat
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 1 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
organophosphate metabolic process GO:0019637 370 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
cardiac muscle cell development GO:0055013 16 0.018
Rat
negative regulation of cell communication GO:0010648 158 0.018
positive regulation of locomotion GO:0040017 102 0.018
response to vitamin a GO:0033189 36 0.017
Rat
regulation of rna biosynthetic process GO:2001141 381 0.017
regulation of ion homeostasis GO:2000021 63 0.017
Rat
male gamete generation GO:0048232 99 0.017
regulation of transferase activity GO:0051338 123 0.017
response to ammonium ion GO:0060359 71 0.017
epithelial cell migration GO:0010631 19 0.017
positive regulation of signal transduction GO:0009967 175 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
Rat
growth GO:0040007 165 0.017
Rat
regulation of cell differentiation GO:0045595 320 0.017
neuron differentiation GO:0030182 368 0.017
blood vessel morphogenesis GO:0048514 58 0.017
Rat
fatty acid derivative metabolic process GO:1901568 38 0.017
chlorinated hydrocarbon metabolic process GO:0042196 4 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
lipid metabolic process GO:0006629 283 0.016
regulation of plasminogen activation GO:0010755 2 0.016
negative regulation of proteolysis GO:0045861 41 0.016
regulation of phospholipase c activity GO:1900274 9 0.016
Rat
vasoconstriction GO:0042310 54 0.016
Rat
signal release GO:0023061 145 0.016
positive regulation of vasodilation GO:0045909 29 0.016
Rat
protein tetramerization GO:0051262 38 0.016
positive regulation of immune effector process GO:0002699 19 0.016
cellular amino acid catabolic process GO:0009063 21 0.016
cellular ion homeostasis GO:0006873 184 0.016
Rat
single organism biosynthetic process GO:0044711 342 0.016
circadian sleep wake cycle process GO:0022410 21 0.016
response to oxidative stress GO:0006979 186 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
Rat
negative regulation of wound healing GO:0061045 8 0.016
hormone secretion GO:0046879 115 0.015
muscle structure development GO:0061061 87 0.015
Rat
regulation of endopeptidase activity GO:0052548 51 0.015
single organism intracellular transport GO:1902582 166 0.015
Rat
cellular response to interleukin 6 GO:0071354 9 0.015
Rat
extracellular matrix organization GO:0030198 13 0.015
Rat
cellular response to fluid shear stress GO:0071498 4 0.015
positive regulation of fibroblast proliferation GO:0048146 15 0.015
Rat
vasculature development GO:0001944 70 0.015
Rat
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.015
cellular response to mechanical stimulus GO:0071260 48 0.015
Rat
single fertilization GO:0007338 3 0.015
organic hydroxy compound transport GO:0015850 77 0.015
Rat
drinking behavior GO:0042756 11 0.015
Rat
positive regulation of cell death GO:0010942 184 0.015
Rat
amide transport GO:0042886 105 0.015
steroid metabolic process GO:0008202 73 0.015
positive regulation of transport GO:0051050 245 0.015
Rat
mesonephric epithelium development GO:0072163 14 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.015
protein complex biogenesis GO:0070271 263 0.015
catecholamine transport GO:0051937 37 0.015
Rat
positive regulation of signaling GO:0023056 270 0.014
tolerance induction dependent upon immune response GO:0002461 2 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
Rat
cellular protein complex assembly GO:0043623 44 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
coenzyme metabolic process GO:0006732 86 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
Rat
cardiac muscle tissue growth GO:0055017 20 0.014
Rat
positive regulation of tolerance induction GO:0002645 1 0.014
transcription dna templated GO:0006351 377 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of protein modification process GO:0031401 142 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
negative regulation of hydrolase activity GO:0051346 52 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
positive regulation of renal sodium excretion GO:0035815 10 0.014
Rat
positive regulation of biosynthetic process GO:0009891 319 0.014
Rat
trichloroethylene metabolic process GO:0018979 1 0.014
cellular response to external stimulus GO:0071496 118 0.014
Rat
cardiac chamber development GO:0003205 1 0.013
rna biosynthetic process GO:0032774 380 0.013
cell activation GO:0001775 97 0.013
circadian sleep wake cycle GO:0042745 23 0.013
epithelial cell proliferation GO:0050673 54 0.013
Rat
protein activation cascade GO:0072376 12 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
negative regulation of epithelial cell proliferation GO:0050680 16 0.013
Rat
positive regulation of cell differentiation GO:0045597 217 0.013
intracellular transport GO:0046907 185 0.013
Rat
response to testosterone GO:0033574 55 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
Rat
excretion GO:0007588 24 0.013
Rat
naphthalene containing compound metabolic process GO:0090420 2 0.013
insulin receptor signaling pathway GO:0008286 24 0.013
cardiac cell development GO:0055006 16 0.013
Rat
positive regulation of developmental process GO:0051094 283 0.013
cofactor metabolic process GO:0051186 95 0.013
response to herbicide GO:0009635 16 0.013
regulation of neuron projection development GO:0010975 161 0.013
liver morphogenesis GO:0072576 3 0.012
response to corticosterone GO:0051412 40 0.012
Rat
sleep GO:0030431 30 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of immune response GO:0050776 55 0.012
cellular response to glucagon stimulus GO:0071377 7 0.012
physiological muscle hypertrophy GO:0003298 13 0.012
Rat
regulation of synaptic transmission GO:0050804 141 0.012
Rat
positive regulation of cell proliferation GO:0008284 249 0.012
Rat
cell type specific apoptotic process GO:0097285 134 0.012
protein localization GO:0008104 191 0.012
Rat
urogenital system development GO:0001655 78 0.012
leukocyte mediated immunity GO:0002443 28 0.012
negative regulation of growth GO:0045926 37 0.012
Rat
purine containing compound metabolic process GO:0072521 253 0.012
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
protein transport GO:0015031 132 0.012
Rat
purine nucleoside metabolic process GO:0042278 169 0.012
mononuclear cell migration GO:0071674 3 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.012
regulation of cellular component organization GO:0051128 368 0.012
Rat
cellular response to peptide GO:1901653 133 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
oxidative demethylation GO:0070989 2 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
Rat
regulation of hormone levels GO:0010817 187 0.012
aromatic compound catabolic process GO:0019439 168 0.011
maternal process involved in parturition GO:0060137 6 0.011
response to cgmp GO:0070305 3 0.011

Serpina1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.354
vascular disease DOID:178 0 0.354
cardiovascular system disease DOID:1287 0 0.354
immune system disease DOID:2914 0 0.226
blood coagulation disease DOID:1247 0 0.226
inherited blood coagulation disease DOID:2214 0 0.226
hematopoietic system disease DOID:74 0 0.226
artery disease DOID:0050828 0 0.052
disease of metabolism DOID:0014667 0 0.017
Human
inherited metabolic disorder DOID:655 0 0.017
Human
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.015
urinary system disease DOID:18 0 0.011