Rattus norvegicus

0 known processes

Serpina6

serine (or cysteine) peptidase inhibitor, clade A, member 6

(Aliases: Cbg,MGC112780)

Serpina6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.293
Rat
tissue development GO:0009888 252 0.266
Rat
response to nutrient GO:0007584 248 0.261
Rat
response to wounding GO:0009611 254 0.223
coagulation GO:0050817 28 0.187
regulation of body fluid levels GO:0050878 90 0.186
cellular ion homeostasis GO:0006873 184 0.158
Rat
fibrinolysis GO:0042730 2 0.147
liver development GO:0001889 90 0.135
programmed cell death GO:0012501 392 0.129
Rat
regulation of cell proliferation GO:0042127 359 0.118
Rat
wound healing GO:0042060 122 0.117
regulation of extracellular matrix constituent secretion GO:0003330 2 0.113
Rat
regulation of apoptotic process GO:0042981 335 0.112
Rat
transmission of nerve impulse GO:0019226 42 0.112
Rat
blood coagulation GO:0007596 26 0.103
positive regulation of extracellular matrix organization GO:1903055 4 0.100
Rat
response to cytokine GO:0034097 215 0.098
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.097
hemostasis GO:0007599 26 0.097
response to vitamin GO:0033273 131 0.096
Rat
macromolecule localization GO:0033036 252 0.095
Rat
response to peptide GO:1901652 292 0.093
Rat
regulation of fibrinolysis GO:0051917 2 0.092
response to metal ion GO:0010038 253 0.092
Rat
carboxylic acid biosynthetic process GO:0046394 83 0.092
regulation of cellular protein metabolic process GO:0032268 267 0.091
Rat
organic acid biosynthetic process GO:0016053 83 0.088
positive regulation of cell proliferation GO:0008284 249 0.087
Rat
intracellular signal transduction GO:0035556 314 0.085
Rat
protein complex biogenesis GO:0070271 263 0.084
oxoacid metabolic process GO:0043436 290 0.083
protein complex assembly GO:0006461 263 0.082
homeostatic process GO:0042592 331 0.081
Rat
regulation of programmed cell death GO:0043067 341 0.081
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.080
Rat
blood circulation GO:0008015 183 0.080
Rat
circulatory system process GO:0003013 183 0.080
Rat
response to nutrient levels GO:0031667 370 0.080
Rat
plasminogen activation GO:0031639 2 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.079
regulation of hemostasis GO:1900046 9 0.078
cellular lipid metabolic process GO:0044255 208 0.078
cellular component biogenesis GO:0044085 368 0.077
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.077
Rat
response to peptide hormone GO:0043434 278 0.077
Rat
positive regulation of blood coagulation GO:0030194 4 0.076
macromolecular complex assembly GO:0065003 273 0.075
lipid biosynthetic process GO:0008610 128 0.074
anatomical structure morphogenesis GO:0009653 298 0.073
Rat
organic acid metabolic process GO:0006082 292 0.068
protein complex subunit organization GO:0071822 302 0.066
multi multicellular organism process GO:0044706 138 0.065
Rat
response to acid chemical GO:0001101 222 0.063
Rat
vasculature development GO:0001944 70 0.063
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.062
cell cell signaling GO:0007267 335 0.062
Rat
glycine metabolic process GO:0006544 7 0.062
negative regulation of developmental process GO:0051093 125 0.062
Rat
cellular homeostasis GO:0019725 252 0.061
Rat
regulation of catalytic activity GO:0050790 304 0.058
Rat
developmental growth GO:0048589 100 0.058
Rat
single organism biosynthetic process GO:0044711 342 0.057
single organism cell adhesion GO:0098602 46 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
cellular response to organic cyclic compound GO:0071407 202 0.056
Rat
regulation of secretion GO:0051046 224 0.056
Rat
monocarboxylic acid transport GO:0015718 52 0.056
response to food GO:0032094 27 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
Rat
amine metabolic process GO:0009308 38 0.055
multi organism reproductive process GO:0044703 262 0.052
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.051
Rat
chemical homeostasis GO:0048878 292 0.050
Rat
regulation of immune system process GO:0002682 123 0.050
negative regulation of epithelial cell proliferation GO:0050680 16 0.050
Rat
proteolysis GO:0006508 175 0.049
Rat
cellular amine metabolic process GO:0044106 38 0.048
immune system process GO:0002376 204 0.048
Rat
regulation of protein metabolic process GO:0051246 289 0.048
Rat
cellular response to nitrogen compound GO:1901699 210 0.048
Rat
nucleic acid templated transcription GO:0097659 379 0.047
divalent metal ion transport GO:0070838 132 0.047
Rat
aging GO:0007568 241 0.047
Rat
growth GO:0040007 165 0.047
Rat
response to inorganic substance GO:0010035 377 0.046
Rat
response to transition metal nanoparticle GO:1990267 122 0.045
Rat
positive regulation of cell death GO:0010942 184 0.045
Rat
positive regulation of biosynthetic process GO:0009891 319 0.044
Rat
regulation of molecular function GO:0065009 398 0.043
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.042
Rat
negative regulation of protein metabolic process GO:0051248 114 0.042
Rat
behavior GO:0007610 205 0.042
Rat
response to vitamin b6 GO:0034516 1 0.041
Rat
renin angiotensin regulation of aldosterone production GO:0002018 3 0.041
Rat
apoptotic process GO:0006915 381 0.040
Rat
negative regulation of metabolic process GO:0009892 331 0.040
Rat
response to ketone GO:1901654 182 0.039
Rat
cellular component assembly GO:0022607 360 0.039
small molecule biosynthetic process GO:0044283 124 0.038
regulation of vasculature development GO:1901342 44 0.038
Rat
response to oxygen levels GO:0070482 265 0.037
Rat
positive regulation of hemostasis GO:1900048 4 0.037
negative regulation of fibrinolysis GO:0051918 2 0.037
positive regulation of response to stimulus GO:0048584 285 0.037
negative regulation of cell death GO:0060548 229 0.035
vascular process in circulatory system GO:0003018 96 0.035
Rat
cellular ketone metabolic process GO:0042180 51 0.035
regulation of hydrolase activity GO:0051336 143 0.034
Rat
cellular sodium ion homeostasis GO:0006883 4 0.034
Rat
macromolecular complex subunit organization GO:0043933 339 0.034
catabolic process GO:0009056 351 0.033
response to decreased oxygen levels GO:0036293 237 0.033
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.033
metal ion transport GO:0030001 289 0.033
Rat
positive regulation of catalytic activity GO:0043085 184 0.033
Rat
divalent inorganic cation transport GO:0072511 134 0.033
Rat
response to triglyceride GO:0034014 3 0.033
Rat
positive regulation of hydrolase activity GO:0051345 86 0.032
Rat
response to chromate GO:0046687 3 0.032
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.032
regulation of protein maturation GO:1903317 50 0.032
Rat
cellular response to organonitrogen compound GO:0071417 197 0.031
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.031
Rat
reproductive process GO:0022414 372 0.031
Rat
fatty acid metabolic process GO:0006631 99 0.031
lipid transport GO:0006869 61 0.031
negative regulation of protein maturation GO:1903318 47 0.031
Rat
biological adhesion GO:0022610 110 0.031
cellular catabolic process GO:0044248 295 0.031
central nervous system development GO:0007417 311 0.031
cell growth GO:0016049 104 0.030
Rat
gland development GO:0048732 155 0.030
protein processing GO:0016485 68 0.030
Rat
response to ionizing radiation GO:0010212 59 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of immune system process GO:0002684 90 0.030
regulation of cell growth GO:0001558 85 0.029
Rat
hepaticobiliary system development GO:0061008 90 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
Rat
cellular response to stress GO:0033554 269 0.029
Rat
negative regulation of apoptotic process GO:0043066 181 0.029
negative regulation of cellular protein metabolic process GO:0032269 106 0.028
Rat
alpha amino acid biosynthetic process GO:1901607 23 0.028
regulation of blood coagulation GO:0030193 9 0.027
regulation of cellular component organization GO:0051128 368 0.027
Rat
mapk cascade GO:0000165 140 0.027
Rat
multicellular organismal signaling GO:0035637 44 0.027
Rat
cellular chemical homeostasis GO:0055082 247 0.027
Rat
organophosphate catabolic process GO:0046434 148 0.027
organic acid catabolic process GO:0016054 49 0.027
multicellular organismal homeostasis GO:0048871 49 0.027
defense response GO:0006952 194 0.027
Rat
cellular response to endogenous stimulus GO:0071495 377 0.027
Rat
regulation of response to external stimulus GO:0032101 106 0.027
head development GO:0060322 247 0.026
response to estrogen GO:0043627 232 0.026
Rat
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.026
Rat
regulation of homeostatic process GO:0032844 101 0.025
Rat
negative regulation of response to stimulus GO:0048585 155 0.025
negative regulation of nervous system development GO:0051961 79 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
regulation of multicellular organismal development GO:2000026 376 0.024
Rat
regulation of tube size GO:0035150 89 0.024
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of signal transduction GO:0009966 318 0.024
regulation of protein processing GO:0070613 50 0.024
Rat
neuron differentiation GO:0030182 368 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
Rat
positive regulation of molecular function GO:0044093 230 0.023
Rat
epithelial cell proliferation GO:0050673 54 0.023
Rat
negative regulation of serine type endopeptidase activity GO:1900004 1 0.023
Rat
positive regulation of protein metabolic process GO:0051247 178 0.023
monocarboxylic acid biosynthetic process GO:0072330 48 0.023
regulation of reactive oxygen species metabolic process GO:2000377 26 0.023
Rat
complement activation GO:0006956 11 0.023
gamete generation GO:0007276 124 0.023
ion homeostasis GO:0050801 212 0.022
Rat
alcohol metabolic process GO:0006066 77 0.022
inflammatory response GO:0006954 150 0.022
Rat
cellular response to external stimulus GO:0071496 118 0.022
Rat
carboxylic acid metabolic process GO:0019752 289 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
Rat
positive regulation of coagulation GO:0050820 5 0.022
chylomicron remodeling GO:0034371 1 0.022
cell adhesion GO:0007155 110 0.021
response to glucocorticoid GO:0051384 223 0.021
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
circulatory system development GO:0072359 134 0.021
Rat
response to corticosteroid GO:0031960 235 0.020
Rat
sterol transport GO:0015918 6 0.020
response to acetate GO:0010034 3 0.020
rna biosynthetic process GO:0032774 380 0.020
ethanolamine containing compound metabolic process GO:0042439 14 0.020
response to toxic substance GO:0009636 133 0.020
establishment of protein localization GO:0045184 141 0.020
Rat
cellular response to lipid GO:0071396 201 0.020
Rat
female pregnancy GO:0007565 122 0.020
Rat
cation homeostasis GO:0055080 195 0.020
Rat
cellular metal ion homeostasis GO:0006875 172 0.020
Rat
positive regulation of response to wounding GO:1903036 34 0.020
organ regeneration GO:0031100 101 0.020
transcription dna templated GO:0006351 377 0.019
regulation of system process GO:0044057 208 0.019
Rat
cell chemotaxis GO:0060326 31 0.019
negative regulation of wound healing GO:0061045 8 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
response to insulin GO:0032868 133 0.019
cellular response to glucocorticoid stimulus GO:0071385 68 0.019
Rat
cellular cation homeostasis GO:0030003 180 0.019
Rat
forebrain development GO:0030900 98 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
reproduction GO:0000003 245 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
response to corticosterone GO:0051412 40 0.018
Rat
regulation of cellular localization GO:0060341 263 0.018
Rat
glycerophospholipid metabolic process GO:0006650 47 0.018
protein localization GO:0008104 191 0.018
Rat
cholesterol transport GO:0030301 5 0.018
reactive nitrogen species metabolic process GO:2001057 1 0.017
single organism reproductive process GO:0044702 297 0.017
organic hydroxy compound transport GO:0015850 77 0.017
Rat
organophosphate metabolic process GO:0019637 370 0.017
single organismal cell cell adhesion GO:0016337 42 0.017
regeneration GO:0031099 163 0.017
response to ethanol GO:0045471 162 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.017
negative regulation of hemostasis GO:1900047 6 0.017
negative regulation of cell growth GO:0030308 33 0.017
Rat
regulation of neuron death GO:1901214 115 0.017
platelet aggregation GO:0070527 4 0.017
secretion GO:0046903 307 0.017
Rat
metal ion homeostasis GO:0055065 186 0.017
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.016
regulation of synaptic transmission GO:0050804 141 0.016
Rat
ribonucleoside metabolic process GO:0009119 174 0.016
cation transport GO:0006812 382 0.016
Rat
response to hexose GO:0009746 144 0.016
immune response GO:0006955 104 0.016
Rat
rna metabolic process GO:0016070 406 0.016
negative regulation of proteolysis GO:0045861 41 0.016
Rat
response to hypoxia GO:0001666 231 0.015
Rat
reactive oxygen species metabolic process GO:0072593 37 0.015
Rat
brain development GO:0007420 247 0.015
renal system process GO:0003014 40 0.015
Rat
hepatocyte proliferation GO:0072574 3 0.015
regulation of secretion by cell GO:1903530 208 0.015
Rat
negative regulation of catalytic activity GO:0043086 103 0.015
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.015
negative regulation of serine type peptidase activity GO:1902572 1 0.015
Rat
organic substance catabolic process GO:1901575 316 0.015
embryonic pattern specification GO:0009880 1 0.015
blood vessel development GO:0001568 69 0.015
Rat
negative regulation of protein processing GO:0010955 47 0.015
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
Rat
negative regulation of blood coagulation GO:0030195 6 0.015
regulation of ion transport GO:0043269 245 0.015
Rat
vasoconstriction GO:0042310 54 0.015
Rat
regulation of neuronal synaptic plasticity GO:0048168 31 0.015
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.014
Rat
brain renin angiotensin system GO:0002035 3 0.014
Rat
single organism catabolic process GO:0044712 283 0.014
regulation of anatomical structure size GO:0090066 135 0.014
Rat
muscle system process GO:0003012 115 0.014
Rat
positive regulation of transport GO:0051050 245 0.014
Rat
organonitrogen compound catabolic process GO:1901565 179 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
Rat
nitrogen compound transport GO:0071705 229 0.014
Rat
purine nucleotide metabolic process GO:0006163 229 0.014
multicellular organism reproduction GO:0032504 233 0.014
spermatogenesis GO:0007283 99 0.014
response to carbohydrate GO:0009743 183 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cellular protein localization GO:0034613 122 0.014
Rat
negative regulation of blood vessel morphogenesis GO:2000181 10 0.014
Rat
regulation of cell projection organization GO:0031344 175 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
response to platinum ion GO:0070541 4 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
regulation of growth GO:0040008 105 0.014
Rat
protein maturation GO:0051604 68 0.013
Rat
response to growth factor GO:0070848 189 0.013
regulation of phosphorylation GO:0042325 248 0.013
nucleotide metabolic process GO:0009117 279 0.013
porphyrin containing compound metabolic process GO:0006778 8 0.013
cellular macromolecule localization GO:0070727 122 0.013
Rat
regulation of response to wounding GO:1903034 69 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
regulation of blood vessel size GO:0050880 89 0.013
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of catabolic process GO:0009896 78 0.013
artery smooth muscle contraction GO:0014824 4 0.013
Rat
response to estradiol GO:0032355 164 0.013
Rat
response to retinoic acid GO:0032526 63 0.013
lipid localization GO:0010876 62 0.013
regulation of angiogenesis GO:0045765 39 0.013
Rat
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of growth GO:0045926 37 0.013
Rat
lipid metabolic process GO:0006629 283 0.013
Mouse
tetrapyrrole metabolic process GO:0033013 11 0.013
regulation of transcription dna templated GO:0006355 374 0.013
sexual reproduction GO:0019953 148 0.012
positive regulation of homeostatic process GO:0032846 49 0.012
Rat
cellular response to mechanical stimulus GO:0071260 48 0.012
Rat
response to camp GO:0051591 91 0.012
Rat
neuron projection development GO:0031175 273 0.012
positive regulation of gene expression GO:0010628 244 0.012
response to vitamin k GO:0032571 4 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
male gamete generation GO:0048232 99 0.012
axis specification GO:0009798 4 0.012
carboxylic acid catabolic process GO:0046395 49 0.012
locomotion GO:0040011 237 0.012
response to activity GO:0014823 73 0.012
Rat
multicellular organismal reproductive process GO:0048609 233 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
ion transmembrane transport GO:0034220 365 0.012
connective tissue development GO:0061448 33 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
protein phosphorylation GO:0006468 345 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.012
Rat
carboxylic acid transport GO:0046942 115 0.012
positive regulation of secretion by cell GO:1903532 128 0.011
Rat
positive regulation of developmental process GO:0051094 283 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
negative regulation of gene expression GO:0010629 199 0.011
Rat
platelet activation GO:0030168 8 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of proteolysis GO:0030162 66 0.011
Rat
cellular response to insulin stimulus GO:0032869 81 0.011
regulation of inflammatory response GO:0050727 48 0.011
secretion by cell GO:0032940 248 0.011
Rat
extracellular matrix constituent secretion GO:0070278 4 0.011
Rat
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
angiogenesis GO:0001525 53 0.011
Rat
organic anion transport GO:0015711 132 0.011
multicellular organism growth GO:0035264 1 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
negative regulation of coagulation GO:0050819 7 0.011
positive regulation of rna metabolic process GO:0051254 203 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
Rat
regulation of cell adhesion GO:0030155 52 0.010
regulation of neurogenesis GO:0050767 247 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
cellular response to oxidative stress GO:0034599 76 0.010
neuron development GO:0048666 286 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
anion transport GO:0006820 178 0.010
regulation of blood pressure GO:0008217 83 0.010
Rat
regulation of blood circulation GO:1903522 110 0.010
Rat

Serpina6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.042
disease of anatomical entity DOID:7 0 0.029
vascular disease DOID:178 0 0.029
cardiovascular system disease DOID:1287 0 0.029
musculoskeletal system disease DOID:17 0 0.027
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.014
acquired metabolic disease DOID:0060158 0 0.013
artery disease DOID:0050828 0 0.013
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
connective tissue disease DOID:65 0 0.012