Rattus norvegicus

48 known processes

Bmpr2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

(Aliases: Bmpr-II)

Bmpr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.303
positive regulation of cellular biosynthetic process GO:0031328 295 0.200
regulation of nucleic acid templated transcription GO:1903506 380 0.196
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.168
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.152
transcription dna templated GO:0006351 377 0.148
regulation of transcription dna templated GO:0006355 374 0.144
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.134
cell projection organization GO:0030030 302 0.125
response to nutrient levels GO:0031667 370 0.122
transcription from rna polymerase ii promoter GO:0006366 252 0.114
regulation of protein metabolic process GO:0051246 289 0.102
rna biosynthetic process GO:0032774 380 0.098
neuron differentiation GO:0030182 368 0.098
cellular component assembly GO:0022607 360 0.096
cellular component biogenesis GO:0044085 368 0.090
nucleic acid templated transcription GO:0097659 379 0.089
regulation of rna metabolic process GO:0051252 391 0.089
single organism reproductive process GO:0044702 297 0.087
positive regulation of gene expression GO:0010628 244 0.085
regulation of phosphorus metabolic process GO:0051174 349 0.084
regulation of rna biosynthetic process GO:2001141 381 0.083
rna metabolic process GO:0016070 406 0.082
neuron projection development GO:0031175 273 0.081
neuron projection morphogenesis GO:0048812 122 0.081
positive regulation of rna biosynthetic process GO:1902680 197 0.080
regulation of cell differentiation GO:0045595 320 0.078
positive regulation of rna metabolic process GO:0051254 203 0.078
central nervous system development GO:0007417 311 0.077
positive regulation of nucleic acid templated transcription GO:1903508 197 0.075
brain development GO:0007420 247 0.073
positive regulation of biosynthetic process GO:0009891 319 0.073
regulation of phosphate metabolic process GO:0019220 349 0.071
regulation of cellular component organization GO:0051128 368 0.070
response to extracellular stimulus GO:0009991 380 0.067
positive regulation of transcription dna templated GO:0045893 197 0.067
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.066
intracellular signal transduction GO:0035556 314 0.066
organelle organization GO:0006996 266 0.065
locomotion GO:0040011 237 0.065
cell motility GO:0048870 202 0.061
reproduction GO:0000003 245 0.060
regulation of molecular function GO:0065009 398 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
sexual reproduction GO:0019953 148 0.058
regulation of neuron differentiation GO:0045664 208 0.057
multi organism reproductive process GO:0044703 262 0.056
response to wounding GO:0009611 254 0.055
protein phosphorylation GO:0006468 345 0.055
developmental process involved in reproduction GO:0003006 159 0.054
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.053
cellular response to hormone stimulus GO:0032870 247 0.053
regulation of cell development GO:0060284 263 0.052
positive regulation of multicellular organismal process GO:0051240 387 0.052
vesicle mediated transport GO:0016192 181 0.050
regulation of multicellular organismal development GO:2000026 376 0.050
tissue development GO:0009888 252 0.050
cellular ketone metabolic process GO:0042180 51 0.050
cellular response to oxygen containing compound GO:1901701 386 0.049
anatomical structure morphogenesis GO:0009653 298 0.049
positive regulation of developmental process GO:0051094 283 0.048
regulation of catalytic activity GO:0050790 304 0.048
regulation of phosphorylation GO:0042325 248 0.048
regulation of cell proliferation GO:0042127 359 0.046
programmed cell death GO:0012501 392 0.046
regulation of cellular protein metabolic process GO:0032268 267 0.045
macromolecular complex subunit organization GO:0043933 339 0.045
response to nutrient GO:0007584 248 0.045
circulatory system process GO:0003013 183 0.045
positive regulation of molecular function GO:0044093 230 0.044
secretion GO:0046903 307 0.043
single organism biosynthetic process GO:0044711 342 0.042
negative regulation of developmental process GO:0051093 125 0.042
protein complex subunit organization GO:0071822 302 0.042
response to corticosteroid GO:0031960 235 0.042
negative regulation of metabolic process GO:0009892 331 0.041
dendrite morphogenesis GO:0048813 43 0.040
oxoacid metabolic process GO:0043436 290 0.040
growth GO:0040007 165 0.039
head development GO:0060322 247 0.038
neuron development GO:0048666 286 0.038
carbohydrate metabolic process GO:0005975 130 0.038
multicellular organism reproduction GO:0032504 233 0.037
regulation of programmed cell death GO:0043067 341 0.037
regulation of signal transduction GO:0009966 318 0.037
reproductive process GO:0022414 372 0.037
negative regulation of cell proliferation GO:0008285 119 0.036
regulation of nervous system development GO:0051960 264 0.035
protein complex biogenesis GO:0070271 263 0.035
regulation of response to stress GO:0080134 126 0.035
positive regulation of catalytic activity GO:0043085 184 0.034
cellular response to peptide GO:1901653 133 0.034
macromolecular complex assembly GO:0065003 273 0.034
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
apoptotic process GO:0006915 381 0.033
response to peptide GO:1901652 292 0.033
epithelium development GO:0060429 96 0.033
organic acid metabolic process GO:0006082 292 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
reproductive system development GO:0061458 128 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
synaptic transmission GO:0007268 235 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
protein complex assembly GO:0006461 263 0.031
axon development GO:0061564 96 0.030
negative regulation of multicellular organismal process GO:0051241 203 0.030
nucleotide metabolic process GO:0009117 279 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.030
cell type specific apoptotic process GO:0097285 134 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
development of primary sexual characteristics GO:0045137 107 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
hepaticobiliary system development GO:0061008 90 0.029
macromolecule localization GO:0033036 252 0.029
regulation of apoptotic process GO:0042981 335 0.029
response to vitamin GO:0033273 131 0.029
biological adhesion GO:0022610 110 0.028
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
cellular response to stress GO:0033554 269 0.027
cellular carbohydrate metabolic process GO:0044262 72 0.027
response to mechanical stimulus GO:0009612 134 0.027
single organism catabolic process GO:0044712 283 0.027
negative regulation of signal transduction GO:0009968 83 0.027
amine metabolic process GO:0009308 38 0.027
defense response GO:0006952 194 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
liver development GO:0001889 90 0.027
endocytosis GO:0006897 84 0.027
cellular catabolic process GO:0044248 295 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
cellular response to insulin stimulus GO:0032869 81 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
sex differentiation GO:0007548 113 0.026
response to estradiol GO:0032355 164 0.025
positive regulation of signaling GO:0023056 270 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
epithelial cell differentiation GO:0030855 71 0.025
cellular amine metabolic process GO:0044106 38 0.025
rhythmic process GO:0048511 156 0.025
gamete generation GO:0007276 124 0.025
regulation of protein modification process GO:0031399 194 0.024
blood circulation GO:0008015 183 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
positive regulation of cell communication GO:0010647 271 0.024
response to growth factor GO:0070848 189 0.024
response to peptide hormone GO:0043434 278 0.024
regulation of neurogenesis GO:0050767 247 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
regulation of transferase activity GO:0051338 123 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
neuron death GO:0070997 127 0.023
circadian rhythm GO:0007623 88 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
response to purine containing compound GO:0014074 126 0.023
gland development GO:0048732 155 0.023
developmental growth GO:0048589 100 0.023
reproductive structure development GO:0048608 128 0.023
cell morphogenesis GO:0000902 142 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
neuron apoptotic process GO:0051402 88 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cellular ion homeostasis GO:0006873 184 0.022
aging GO:0007568 241 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
response to glucocorticoid GO:0051384 223 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
transmission of nerve impulse GO:0019226 42 0.021
regulation of cell adhesion GO:0030155 52 0.021
intracellular transport GO:0046907 185 0.021
protein localization GO:0008104 191 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
cell growth GO:0016049 104 0.021
positive regulation of cell death GO:0010942 184 0.021
tube development GO:0035295 89 0.021
regulation of neuron projection development GO:0010975 161 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
immune system process GO:0002376 204 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
homeostatic process GO:0042592 331 0.020
response to monosaccharide GO:0034284 159 0.020
lipid metabolic process GO:0006629 283 0.020
organophosphate metabolic process GO:0019637 370 0.020
regulation of vesicle mediated transport GO:0060627 81 0.020
regulation of protein kinase activity GO:0045859 105 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
response to decreased oxygen levels GO:0036293 237 0.020
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
synaptic growth at neuromuscular junction GO:0051124 1 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
muscle system process GO:0003012 115 0.019
regulation of growth GO:0040008 105 0.019
development of primary female sexual characteristics GO:0046545 56 0.019
regulation of cell motility GO:2000145 131 0.019
jak stat cascade GO:0007259 26 0.019
positive regulation of transport GO:0051050 245 0.019
organ formation GO:0048645 3 0.019
multicellular organism growth GO:0035264 1 0.019
response to metal ion GO:0010038 253 0.019
cellular response to external stimulus GO:0071496 118 0.018
cell projection morphogenesis GO:0048858 123 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
catabolic process GO:0009056 351 0.018
regulation of kinase activity GO:0043549 117 0.018
positive regulation of signal transduction GO:0009967 175 0.018
cell cell signaling GO:0007267 335 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
response to oxygen levels GO:0070482 265 0.018
organic substance catabolic process GO:1901575 316 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
cellular component movement GO:0006928 248 0.018
dephosphorylation GO:0016311 98 0.018
dendrite development GO:0016358 72 0.018
striated muscle tissue development GO:0014706 58 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
gonad development GO:0008406 104 0.017
centrosome organization GO:0051297 1 0.017
anterior posterior pattern specification GO:0009952 1 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
muscle structure development GO:0061061 87 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to ethanol GO:0045471 162 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
positive regulation of nervous system development GO:0051962 178 0.017
ras protein signal transduction GO:0007265 29 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
response to oxidative stress GO:0006979 186 0.017
ion transmembrane transport GO:0034220 365 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
lipid storage GO:0019915 1 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
motor neuron axon guidance GO:0008045 1 0.016
regulation of immune system process GO:0002682 123 0.016
positive regulation of protein binding GO:0032092 9 0.016
ion homeostasis GO:0050801 212 0.016
regulation of cellular localization GO:0060341 263 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
regulation of blood vessel size GO:0050880 89 0.016
cellular component morphogenesis GO:0032989 155 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
response to radiation GO:0009314 137 0.016
chemical homeostasis GO:0048878 292 0.016
cell migration GO:0016477 197 0.016
regulation of mapk cascade GO:0043408 116 0.016
peptidyl amino acid modification GO:0018193 126 0.016
regulation of phagocytosis engulfment GO:0060099 4 0.016
non canonical wnt signaling pathway GO:0035567 3 0.015
negative regulation of cell communication GO:0010648 158 0.015
response to camp GO:0051591 91 0.015
transmembrane transport GO:0055085 412 0.015
heart morphogenesis GO:0003007 3 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
protein transport GO:0015031 132 0.015
cell adhesion GO:0007155 110 0.015
maintenance of location GO:0051235 17 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
regulation of neuron death GO:1901214 115 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
response to carbohydrate GO:0009743 183 0.015
smooth muscle cell migration GO:0014909 36 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
response to hypoxia GO:0001666 231 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
negative regulation of nervous system development GO:0051961 79 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
single organism intracellular transport GO:1902582 166 0.015
b cell differentiation GO:0030183 2 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
regulation of cell cycle GO:0051726 73 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
regulation of cell projection organization GO:0031344 175 0.014
male gonad development GO:0008584 59 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
male gamete generation GO:0048232 99 0.014
regulation of membrane potential GO:0042391 110 0.014
regulation of system process GO:0044057 208 0.014
purine containing compound metabolic process GO:0072521 253 0.014
female pregnancy GO:0007565 122 0.014
salivary gland morphogenesis GO:0007435 1 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
forebrain development GO:0030900 98 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
chromosome segregation GO:0007059 2 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
cation homeostasis GO:0055080 195 0.014
negative regulation of rna metabolic process GO:0051253 123 0.013
lens fiber cell differentiation GO:0070306 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of gluconeogenesis GO:0006111 4 0.013
chemotaxis GO:0006935 66 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to insulin GO:0032868 133 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
proteolysis GO:0006508 175 0.013
negative regulation of transport GO:0051051 136 0.013
positive regulation of phagocytosis engulfment GO:0060100 4 0.013
gastrulation GO:0007369 2 0.013
negative regulation of cell death GO:0060548 229 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
cell cycle GO:0007049 101 0.013
response to hexose GO:0009746 144 0.013
response to ketone GO:1901654 182 0.013
lipid biosynthetic process GO:0008610 128 0.013
regulation of muscle system process GO:0090257 79 0.013
regulation of body fluid levels GO:0050878 90 0.013
nucleoside metabolic process GO:0009116 179 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
coenzyme metabolic process GO:0006732 86 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
spermatogenesis GO:0007283 99 0.013
regulation of cell migration GO:0030334 128 0.013
inflammatory response GO:0006954 150 0.013
regulation of developmental growth GO:0048638 45 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
spindle organization GO:0007051 2 0.013
regulation of fat cell differentiation GO:0045598 3 0.013
cardiovascular system development GO:0072358 134 0.013
nucleotide catabolic process GO:0009166 139 0.013
guanosine containing compound catabolic process GO:1901069 71 0.013
response to biotic stimulus GO:0009607 226 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
asymmetric protein localization GO:0008105 2 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
translation GO:0006412 35 0.012
negative regulation of cell development GO:0010721 82 0.012
cytoplasmic transport GO:0016482 115 0.012
response to estrogen GO:0043627 232 0.012
response to glucose GO:0009749 136 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
axis specification GO:0009798 4 0.012
male sex differentiation GO:0046661 64 0.012
establishment of protein localization GO:0045184 141 0.012
cellular response to lipid GO:0071396 201 0.012
regulation of hydrolase activity GO:0051336 143 0.012
localization of cell GO:0051674 202 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.012
positive regulation of kinase activity GO:0033674 77 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
negative regulation of gene expression GO:0010629 199 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of response to external stimulus GO:0032103 51 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
cell part morphogenesis GO:0032990 123 0.012
multicellular organismal signaling GO:0035637 44 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
bmp signaling pathway GO:0030509 4 0.012
retinoic acid receptor signaling pathway GO:0048384 7 0.012
microtubule organizing center organization GO:0031023 1 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
response to inorganic substance GO:0010035 377 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
cellular cation homeostasis GO:0030003 180 0.011
formation of primary germ layer GO:0001704 1 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
regulation of mesenchymal cell proliferation GO:0010464 4 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
mitotic spindle organization GO:0007052 2 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
olfactory learning GO:0008355 1 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
rab protein signal transduction GO:0032482 1 0.011
muscle contraction GO:0006936 88 0.011
oxidation reduction process GO:0055114 304 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
cellular homeostasis GO:0019725 252 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
heterocycle catabolic process GO:0046700 167 0.011
phagocytosis GO:0006909 17 0.011
response to mineralocorticoid GO:0051385 49 0.011
chemosensory behavior GO:0007635 2 0.011
positive regulation of transferase activity GO:0051347 81 0.011
cellular response to hypoxia GO:0071456 51 0.011
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of cell development GO:0010720 176 0.011
response to acid chemical GO:0001101 222 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of signaling GO:0023057 157 0.011
sensory organ development GO:0007423 74 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
regulation of bmp signaling pathway GO:0030510 2 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
negative regulation of phosphorylation GO:0042326 57 0.010
positive regulation of locomotion GO:0040017 102 0.010
regulation of response to external stimulus GO:0032101 106 0.010
protein oligomerization GO:0051259 191 0.010
regulation of notch signaling pathway GO:0008593 3 0.010
cell cell junction organization GO:0045216 20 0.010
response to bacterium GO:0009617 200 0.010
cell activation GO:0001775 97 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
regulation of locomotion GO:0040012 148 0.010
aromatic compound catabolic process GO:0019439 168 0.010
single organismal cell cell adhesion GO:0016337 42 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
vasculogenesis GO:0001570 3 0.010
embryonic placenta development GO:0001892 1 0.010
neurological system process GO:0050877 219 0.010
single organism organelle organization GO:1902589 180 0.010

Bmpr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015