Rattus norvegicus

0 known processes

Elk4

ELK4, ETS-domain protein (SRF accessory protein 1)

Elk4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular biosynthetic process GO:0031328 295 0.081
Rat
cellular ketone metabolic process GO:0042180 51 0.078
cellular amino acid metabolic process GO:0006520 107 0.074
immune system process GO:0002376 204 0.073
regulation of cell proliferation GO:0042127 359 0.072
organic acid metabolic process GO:0006082 292 0.066
protein phosphorylation GO:0006468 345 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
Rat
cellular component movement GO:0006928 248 0.060
intracellular signal transduction GO:0035556 314 0.055
cellular response to nitrogen compound GO:1901699 210 0.053
positive regulation of gene expression GO:0010628 244 0.052
Rat
regulation of signal transduction GO:0009966 318 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.048
rna metabolic process GO:0016070 406 0.048
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.047
regulation of programmed cell death GO:0043067 341 0.046
regulation of rna metabolic process GO:0051252 391 0.044
Rat
cellular response to stress GO:0033554 269 0.044
programmed cell death GO:0012501 392 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.043
amine metabolic process GO:0009308 38 0.042
transcription dna templated GO:0006351 377 0.041
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.041
neuron differentiation GO:0030182 368 0.040
apoptotic process GO:0006915 381 0.039
carboxylic acid metabolic process GO:0019752 289 0.039
cellular amine metabolic process GO:0044106 38 0.039
positive regulation of cell proliferation GO:0008284 249 0.038
regulation of immune system process GO:0002682 123 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
regulation of apoptotic process GO:0042981 335 0.037
rna biosynthetic process GO:0032774 380 0.037
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.037
Rat
regulation of phosphate metabolic process GO:0019220 349 0.036
motor neuron axon guidance GO:0008045 1 0.036
oxoacid metabolic process GO:0043436 290 0.035
regulation of protein modification process GO:0031399 194 0.033
regulation of transcription dna templated GO:0006355 374 0.033
Rat
reproductive process GO:0022414 372 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
single organism biosynthetic process GO:0044711 342 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.032
eye morphogenesis GO:0048592 4 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.031
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.030
regulation of nervous system development GO:0051960 264 0.030
anatomical structure morphogenesis GO:0009653 298 0.030
regulation of cellular component organization GO:0051128 368 0.029
negative regulation of signaling GO:0023057 157 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
immune system development GO:0002520 41 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
Rat
sensory organ development GO:0007423 74 0.027
positive regulation of cell communication GO:0010647 271 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
Rat
cation transport GO:0006812 382 0.027
nucleic acid templated transcription GO:0097659 379 0.027
Rat
neuron projection development GO:0031175 273 0.027
localization of cell GO:0051674 202 0.027
positive regulation of protein metabolic process GO:0051247 178 0.026
regulation of neurogenesis GO:0050767 247 0.026
cell motility GO:0048870 202 0.025
erythrocyte differentiation GO:0030218 1 0.025
negative regulation of molecular function GO:0044092 133 0.025
negative regulation of signal transduction GO:0009968 83 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
central nervous system development GO:0007417 311 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
Rat
regulation of molecular function GO:0065009 398 0.025
positive regulation of transport GO:0051050 245 0.025
regulation of system process GO:0044057 208 0.024
single organism reproductive process GO:0044702 297 0.024
peptidyl amino acid modification GO:0018193 126 0.024
response to bacterium GO:0009617 200 0.024
response to nutrient levels GO:0031667 370 0.024
locomotion GO:0040011 237 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
regulation of protein metabolic process GO:0051246 289 0.023
cell migration GO:0016477 197 0.023
homeostatic process GO:0042592 331 0.023
negative regulation of metabolic process GO:0009892 331 0.023
regulation of cell differentiation GO:0045595 320 0.023
regulation of cell projection organization GO:0031344 175 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
Rat
regulation of neuron differentiation GO:0045664 208 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
transmembrane transport GO:0055085 412 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
regulation of growth GO:0040008 105 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
response to extracellular stimulus GO:0009991 380 0.021
positive regulation of response to external stimulus GO:0032103 51 0.021
regulation of canonical wnt signaling pathway GO:0060828 4 0.021
gliogenesis GO:0042063 93 0.020
positive regulation of locomotion GO:0040017 102 0.020
axis specification GO:0009798 4 0.020
camera type eye morphogenesis GO:0048593 2 0.020
negative regulation of cell communication GO:0010648 158 0.020
organelle organization GO:0006996 266 0.020
regulation of cellular component movement GO:0051270 150 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
organic substance catabolic process GO:1901575 316 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
positive regulation of cell development GO:0010720 176 0.019
ion transmembrane transport GO:0034220 365 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
Rat
chemical homeostasis GO:0048878 292 0.019
regulation of phosphorylation GO:0042325 248 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
reproduction GO:0000003 245 0.018
multicellular organism reproduction GO:0032504 233 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
Rat
hematopoietic progenitor cell differentiation GO:0002244 2 0.018
cation transmembrane transport GO:0098655 263 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
Rat
heart morphogenesis GO:0003007 3 0.018
aromatic compound catabolic process GO:0019439 168 0.018
response to wounding GO:0009611 254 0.018
peptidyl tyrosine phosphorylation GO:0018108 72 0.018
neuron development GO:0048666 286 0.018
regulation of hormone secretion GO:0046883 106 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
Rat
regulation of cell growth GO:0001558 85 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regeneration GO:0031099 163 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
cellular component biogenesis GO:0044085 368 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
regulation of cell migration GO:0030334 128 0.017
multi organism reproductive process GO:0044703 262 0.017
neuron projection morphogenesis GO:0048812 122 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
purine containing compound metabolic process GO:0072521 253 0.017
camera type eye development GO:0043010 48 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
response to other organism GO:0051707 220 0.017
response to metal ion GO:0010038 253 0.016
nucleotide metabolic process GO:0009117 279 0.016
negative regulation of gene expression GO:0010629 199 0.016
response to inorganic substance GO:0010035 377 0.016
response to peptide GO:1901652 292 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
cell projection organization GO:0030030 302 0.016
glial cell differentiation GO:0010001 65 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of locomotion GO:0040012 148 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
head development GO:0060322 247 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
Rat
negative regulation of cell cycle phase transition GO:1901988 4 0.015
multi multicellular organism process GO:0044706 138 0.015
metal ion transport GO:0030001 289 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
negative regulation of developmental process GO:0051093 125 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
eye development GO:0001654 50 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
response to growth factor GO:0070848 189 0.015
metal ion homeostasis GO:0055065 186 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
cellular chemical homeostasis GO:0055082 247 0.015
regulation of cell development GO:0060284 263 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
catabolic process GO:0009056 351 0.014
regulation of catalytic activity GO:0050790 304 0.014
positive regulation of molecular function GO:0044093 230 0.014
ion homeostasis GO:0050801 212 0.014
lipid metabolic process GO:0006629 283 0.014
gland development GO:0048732 155 0.014
secretion by cell GO:0032940 248 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
brain development GO:0007420 247 0.014
secretion GO:0046903 307 0.014
cell part morphogenesis GO:0032990 123 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
response to cytokine GO:0034097 215 0.014
cell cycle checkpoint GO:0000075 2 0.014
response to external biotic stimulus GO:0043207 221 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
jak stat cascade GO:0007259 26 0.013
muscle system process GO:0003012 115 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
proteolysis GO:0006508 175 0.013
cellular macromolecule localization GO:0070727 122 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
bmp signaling pathway GO:0030509 4 0.013
heart contraction GO:0060047 57 0.013
reproductive system development GO:0061458 128 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
glandular epithelial cell differentiation GO:0002067 4 0.013
regulation of organ formation GO:0003156 2 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
regulation of response to stress GO:0080134 126 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
growth GO:0040007 165 0.013
defense response GO:0006952 194 0.013
response to insulin GO:0032868 133 0.013
regulation of anatomical structure size GO:0090066 135 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
macromolecular complex assembly GO:0065003 273 0.013
organ regeneration GO:0031100 101 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
inorganic cation transmembrane transport GO:0098662 202 0.012
ras protein signal transduction GO:0007265 29 0.012
cell projection morphogenesis GO:0048858 123 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of response to external stimulus GO:0032101 106 0.012
response to biotic stimulus GO:0009607 226 0.012
developmental process involved in reproduction GO:0003006 159 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
liver development GO:0001889 90 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
dna metabolic process GO:0006259 96 0.012
cell cycle GO:0007049 101 0.012
embryonic skeletal system development GO:0048706 3 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
Rat
positive regulation of cell death GO:0010942 184 0.012
Rat
positive regulation of growth GO:0045927 55 0.012
cellular response to peptide GO:1901653 133 0.012
cation homeostasis GO:0055080 195 0.012
t cell activation GO:0042110 29 0.012
cellular protein complex assembly GO:0043623 44 0.012
sexual reproduction GO:0019953 148 0.012
macromolecule localization GO:0033036 252 0.011
negative regulation of cell death GO:0060548 229 0.011
sex differentiation GO:0007548 113 0.011
cellular component assembly GO:0022607 360 0.011
single organism organelle organization GO:1902589 180 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
ossification GO:0001503 70 0.011
cell cycle g1 s phase transition GO:0044843 13 0.011
organ morphogenesis GO:0009887 75 0.011
epithelium development GO:0060429 96 0.011
gamete generation GO:0007276 124 0.011
positive regulation of signaling GO:0023056 270 0.011
hepaticobiliary system development GO:0061008 90 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
heterocycle catabolic process GO:0046700 167 0.011
mesoderm development GO:0007498 2 0.011
nitrogen compound transport GO:0071705 229 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
b cell differentiation GO:0030183 2 0.011
dephosphorylation GO:0016311 98 0.011
cellular response to lipid GO:0071396 201 0.011
Rat
cellular catabolic process GO:0044248 295 0.011
auditory receptor cell differentiation GO:0042491 2 0.011
regulation of secretion by cell GO:1903530 208 0.011
anterior posterior pattern specification GO:0009952 1 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
negative regulation of transport GO:0051051 136 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cell cell signaling GO:0007267 335 0.011
calcium ion homeostasis GO:0055074 162 0.011
hematopoietic or lymphoid organ development GO:0048534 36 0.011
regulation of cell cycle g1 s phase transition GO:1902806 7 0.011
male gamete generation GO:0048232 99 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
regulation of cellular localization GO:0060341 263 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
actin cytoskeleton organization GO:0030036 73 0.010
reproductive structure development GO:0048608 128 0.010
skeletal system development GO:0001501 41 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
single organism behavior GO:0044708 130 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
regulation of neuron projection development GO:0010975 161 0.010
protein complex biogenesis GO:0070271 263 0.010
organophosphate metabolic process GO:0019637 370 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010

Elk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
large intestine cancer DOID:5672 0 0.013
colon cancer DOID:219 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
colorectal cancer DOID:9256 0 0.013
disease of anatomical entity DOID:7 0 0.013
cardiovascular system disease DOID:1287 0 0.013
nervous system disease DOID:863 0 0.010