Rattus norvegicus

98 known processes

Stat5a

signal transducer and activator of transcription 5A

(Aliases: Stat5)

Stat5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to oxygen containing compound GO:1901701 386 0.255
Mouse Rat Fly
cellular response to nitrogen compound GO:1901699 210 0.174
Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.173
Mouse Rat
cellular component biogenesis GO:0044085 368 0.162
cellular component assembly GO:0022607 360 0.156
positive regulation of locomotion GO:0040017 102 0.150
response to peptide GO:1901652 292 0.148
Mouse Rat
response to nutrient levels GO:0031667 370 0.145
positive regulation of cellular component movement GO:0051272 102 0.144
Rat
programmed cell death GO:0012501 392 0.138
Mouse
regulation of programmed cell death GO:0043067 341 0.132
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.131
Fly
response to other organism GO:0051707 220 0.110
Rat Fly
positive regulation of cell proliferation GO:0008284 249 0.105
Mouse Rat Fly
cellular response to lipid GO:0071396 201 0.104
Fly
transcription dna templated GO:0006351 377 0.101
cell chemotaxis GO:0060326 31 0.101
cytokine mediated signaling pathway GO:0019221 43 0.098
Mouse Rat
homeostatic process GO:0042592 331 0.097
Zebrafish Mouse
protein complex assembly GO:0006461 263 0.097
positive regulation of cell communication GO:0010647 271 0.096
protein oligomerization GO:0051259 191 0.090
protein complex biogenesis GO:0070271 263 0.089
response to biotic stimulus GO:0009607 226 0.087
Rat Fly
cardiovascular system development GO:0072358 134 0.086
positive regulation of developmental process GO:0051094 283 0.085
Zebrafish Mouse
response to metal ion GO:0010038 253 0.084
cellular response to cytokine stimulus GO:0071345 127 0.083
Mouse Rat
regulation of cell differentiation GO:0045595 320 0.082
Zebrafish Mouse Rat Fly
response to carbohydrate GO:0009743 183 0.082
regulation of cell proliferation GO:0042127 359 0.080
Mouse Rat Fly
reproductive process GO:0022414 372 0.080
protein complex subunit organization GO:0071822 302 0.079
macromolecular complex assembly GO:0065003 273 0.079
response to inorganic substance GO:0010035 377 0.077
Rat
cellular chemical homeostasis GO:0055082 247 0.076
regulation of multicellular organismal development GO:2000026 376 0.075
Zebrafish Mouse Rat
locomotion GO:0040011 237 0.073
Fly
regulation of immune system process GO:0002682 123 0.073
Zebrafish Mouse Fly
regulation of cellular component movement GO:0051270 150 0.073
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.072
Zebrafish Mouse
circulatory system development GO:0072359 134 0.070
lipid metabolic process GO:0006629 283 0.070
Mouse
immune system process GO:0002376 204 0.068
Zebrafish Mouse Fly
macromolecular complex subunit organization GO:0043933 339 0.067
single organism biosynthetic process GO:0044711 342 0.065
Rat
organophosphate metabolic process GO:0019637 370 0.064
Rat
positive regulation of immune system process GO:0002684 90 0.064
Zebrafish Mouse
positive regulation of cell motility GO:2000147 97 0.064
blood vessel morphogenesis GO:0048514 58 0.063
response to oxygen levels GO:0070482 265 0.061
Rat
response to molecule of bacterial origin GO:0002237 194 0.061
Rat Fly
tissue development GO:0009888 252 0.059
Mouse Rat Fly
regulation of signal transduction GO:0009966 318 0.059
Fly
carboxylic acid metabolic process GO:0019752 289 0.058
Mouse
aging GO:0007568 241 0.058
Rat
cellular response to acid chemical GO:0071229 75 0.057
oxoacid metabolic process GO:0043436 290 0.056
Mouse
cell migration GO:0016477 197 0.056
Fly
cellular lipid metabolic process GO:0044255 208 0.055
Mouse
cellular response to organic cyclic compound GO:0071407 202 0.055
response to external biotic stimulus GO:0043207 221 0.054
Rat Fly
response to extracellular stimulus GO:0009991 380 0.053
negative regulation of cell differentiation GO:0045596 99 0.053
Mouse Rat Fly
response to nutrient GO:0007584 248 0.052
Rat
localization of cell GO:0051674 202 0.052
Fly
vasculature development GO:0001944 70 0.052
positive regulation of cell development GO:0010720 176 0.051
catabolic process GO:0009056 351 0.051
positive regulation of ion transport GO:0043270 94 0.050
monocarboxylic acid metabolic process GO:0032787 152 0.050
Mouse
innate immune response GO:0045087 35 0.050
Mouse
positive regulation of cell migration GO:0030335 96 0.050
positive regulation of transport GO:0051050 245 0.048
purine nucleotide metabolic process GO:0006163 229 0.048
Rat
synaptic transmission GO:0007268 235 0.048
positive regulation of signaling GO:0023056 270 0.047
cellular response to organonitrogen compound GO:0071417 197 0.047
Mouse Rat
chemical homeostasis GO:0048878 292 0.046
response to hypoxia GO:0001666 231 0.046
Rat
cellular response to molecule of bacterial origin GO:0071219 56 0.046
Fly
regulation of cell projection organization GO:0031344 175 0.046
regulation of catalytic activity GO:0050790 304 0.045
nucleic acid templated transcription GO:0097659 379 0.045
blood vessel development GO:0001568 69 0.045
positive regulation of signal transduction GO:0009967 175 0.045
rna biosynthetic process GO:0032774 380 0.043
positive regulation of response to stimulus GO:0048584 285 0.043
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.043
Rat
divalent inorganic cation transport GO:0072511 134 0.042
cation transport GO:0006812 382 0.042
regulation of locomotion GO:0040012 148 0.041
positive regulation of angiogenesis GO:0045766 28 0.041
response to monosaccharide GO:0034284 159 0.040
regulation of cell motility GO:2000145 131 0.040
central nervous system development GO:0007417 311 0.039
inorganic cation transmembrane transport GO:0098662 202 0.039
cellular response to oxidative stress GO:0034599 76 0.039
Rat
cell cell signaling GO:0007267 335 0.039
cellular catabolic process GO:0044248 295 0.038
apoptotic process GO:0006915 381 0.038
Mouse
renal system development GO:0072001 67 0.038
Rat
regulation of apoptotic process GO:0042981 335 0.038
Mouse
response to ammonium ion GO:0060359 71 0.037
cellular homeostasis GO:0019725 252 0.037
leukocyte migration GO:0050900 38 0.036
ribose phosphate metabolic process GO:0019693 235 0.036
Rat
mesoderm development GO:0007498 2 0.036
ion homeostasis GO:0050801 212 0.036
metal ion transport GO:0030001 289 0.036
cell motility GO:0048870 202 0.036
Fly
regulation of rna metabolic process GO:0051252 391 0.036
single organism reproductive process GO:0044702 297 0.035
Mouse Rat Fly
response to lipopolysaccharide GO:0032496 191 0.035
Rat Fly
secretion by cell GO:0032940 248 0.035
positive regulation of molecular function GO:0044093 230 0.035
intracellular transport GO:0046907 185 0.035
Rat
response to acid chemical GO:0001101 222 0.035
multi multicellular organism process GO:0044706 138 0.034
Mouse
regulation of molecular function GO:0065009 398 0.034
cellular response to stress GO:0033554 269 0.034
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.033
Fly
cellular ketone metabolic process GO:0042180 51 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
protein phosphorylation GO:0006468 345 0.032
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.032
response to peptide hormone GO:0043434 278 0.032
Mouse Rat
regulation of neurogenesis GO:0050767 247 0.032
intracellular signal transduction GO:0035556 314 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.032
cell projection organization GO:0030030 302 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
Rat
cellular response to hormone stimulus GO:0032870 247 0.031
Mouse Rat
regulation of protein metabolic process GO:0051246 289 0.031
Mouse
female pregnancy GO:0007565 122 0.031
Mouse
transmembrane transport GO:0055085 412 0.031
neuron differentiation GO:0030182 368 0.030
cellular response to biotic stimulus GO:0071216 59 0.030
Fly
ribonucleoside metabolic process GO:0009119 174 0.030
Rat
myeloid leukocyte differentiation GO:0002573 20 0.030
Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.030
Rat
negative regulation of programmed cell death GO:0043069 183 0.030
Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.029
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.029
alcohol metabolic process GO:0006066 77 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
Rat
response to amino acid GO:0043200 75 0.028
response to radiation GO:0009314 137 0.028
Fly
response to hexose GO:0009746 144 0.028
multi organism reproductive process GO:0044703 262 0.028
Mouse Fly
organic acid metabolic process GO:0006082 292 0.027
Mouse
response to bacterium GO:0009617 200 0.027
Rat Fly
regulation of secretion GO:0051046 224 0.027
negative regulation of cell proliferation GO:0008285 119 0.027
proteolysis GO:0006508 175 0.027
regulation of cellular component organization GO:0051128 368 0.027
Rat
metal ion homeostasis GO:0055065 186 0.026
regulation of nervous system development GO:0051960 264 0.026
cellular response to external stimulus GO:0071496 118 0.026
cellular amine metabolic process GO:0044106 38 0.026
amine metabolic process GO:0009308 38 0.026
rna metabolic process GO:0016070 406 0.026
reproduction GO:0000003 245 0.026
gland development GO:0048732 155 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.025
response to vitamin GO:0033273 131 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
Rat
inorganic ion transmembrane transport GO:0098660 229 0.025
regulation of cell migration GO:0030334 128 0.024
myeloid leukocyte migration GO:0097529 20 0.024
negative regulation of metabolic process GO:0009892 331 0.024
Rat
regulation of cellular localization GO:0060341 263 0.024
negative regulation of homeostatic process GO:0032845 47 0.024
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
response to alkaloid GO:0043279 132 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.023
Rat
organelle organization GO:0006996 266 0.023
Rat
response to ionizing radiation GO:0010212 59 0.023
Fly
cytokine production GO:0001816 61 0.023
Mouse
regulation of smooth muscle cell migration GO:0014910 36 0.023
positive regulation of cell death GO:0010942 184 0.023
secretion GO:0046903 307 0.023
regulation of hydrolase activity GO:0051336 143 0.023
regulation of canonical wnt signaling pathway GO:0060828 4 0.023
multicellular organism reproduction GO:0032504 233 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
carbohydrate metabolic process GO:0005975 130 0.022
reactive oxygen species metabolic process GO:0072593 37 0.022
Rat
positive regulation of gene expression GO:0010628 244 0.022
Zebrafish Mouse Rat Fly
regulation of transcription dna templated GO:0006355 374 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
Rat
negative regulation of apoptotic process GO:0043066 181 0.022
Mouse
single organism intracellular transport GO:1902582 166 0.022
Rat
neuron development GO:0048666 286 0.022
regulation of response to external stimulus GO:0032101 106 0.022
Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
Zebrafish Mouse Rat Fly
cation transmembrane transport GO:0098655 263 0.021
response to interleukin 1 GO:0070555 55 0.021
neuron projection development GO:0031175 273 0.021
cellular response to alcohol GO:0097306 87 0.021
positive regulation of rna metabolic process GO:0051254 203 0.020
Zebrafish Mouse Rat Fly
nucleoside phosphate metabolic process GO:0006753 283 0.020
Rat
positive regulation of neurogenesis GO:0050769 165 0.020
regulation of neuron differentiation GO:0045664 208 0.020
response to cytokine GO:0034097 215 0.020
Mouse Rat
purine ribonucleotide metabolic process GO:0009150 227 0.020
Rat
purine containing compound metabolic process GO:0072521 253 0.020
Rat
positive regulation of smooth muscle cell migration GO:0014911 27 0.020
protein localization GO:0008104 191 0.020
positive regulation of secretion GO:0051047 140 0.020
reactive nitrogen species metabolic process GO:2001057 1 0.020
response to amine GO:0014075 46 0.020
calcium ion homeostasis GO:0055074 162 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
Mouse
purine nucleoside metabolic process GO:0042278 169 0.019
Rat
response to glucose GO:0009749 136 0.019
chemotaxis GO:0006935 66 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
Mouse Rat
positive regulation of hydrolase activity GO:0051345 86 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
regulation of hormone levels GO:0010817 187 0.019
regulation of vasculature development GO:1901342 44 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.018
calcium ion transport GO:0006816 131 0.018
regulation of cell development GO:0060284 263 0.018
Rat
urogenital system development GO:0001655 78 0.018
Mouse Rat
cellular response to ketone GO:1901655 51 0.018
regulation of epithelial cell proliferation GO:0050678 49 0.018
cytoplasmic transport GO:0016482 115 0.018
regulation of cytokine production GO:0001817 56 0.018
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.017
Rat
response to oxidative stress GO:0006979 186 0.017
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.017
Rat
response to camp GO:0051591 91 0.017
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
Zebrafish Mouse Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
regulation of angiogenesis GO:0045765 39 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of neuron projection development GO:0010975 161 0.017
positive regulation of protein kinase activity GO:0045860 73 0.016
positive regulation of nervous system development GO:0051962 178 0.016
ion transmembrane transport GO:0034220 365 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
angiogenesis GO:0001525 53 0.016
defense response GO:0006952 194 0.016
Mouse Rat Fly
regulation of synaptic transmission GO:0050804 141 0.016
regulation of mapk cascade GO:0043408 116 0.016
regulation of phosphorylation GO:0042325 248 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
positive regulation of calcium ion transport GO:0051928 36 0.016
nucleotide metabolic process GO:0009117 279 0.016
Rat
anatomical structure morphogenesis GO:0009653 298 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
Zebrafish Mouse Rat Fly
immune response GO:0006955 104 0.016
Mouse Fly
anion transport GO:0006820 178 0.016
macromolecule localization GO:0033036 252 0.016
Mouse
cell activation GO:0001775 97 0.015
Zebrafish Mouse
membrane organization GO:0061024 94 0.015
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
cellular ion homeostasis GO:0006873 184 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
muscle system process GO:0003012 115 0.015
response to decreased oxygen levels GO:0036293 237 0.015
Rat
protein homooligomerization GO:0051260 91 0.015
ras protein signal transduction GO:0007265 29 0.015
response to estradiol GO:0032355 164 0.015
Rat
regulation of system process GO:0044057 208 0.015
regeneration GO:0031099 163 0.015
calcium ion transport into cytosol GO:0060402 38 0.015
response to ketone GO:1901654 182 0.015
multicellular organism growth GO:0035264 1 0.015
Mouse
single organism carbohydrate metabolic process GO:0044723 118 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
purine containing compound catabolic process GO:0072523 138 0.015
cognition GO:0050890 92 0.015
Fly
nucleoside metabolic process GO:0009116 179 0.014
Rat
response to corticosteroid GO:0031960 235 0.014
divalent metal ion transport GO:0070838 132 0.014
skeletal system development GO:0001501 41 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
Rat
oxidation reduction process GO:0055114 304 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
anion transmembrane transport GO:0098656 77 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
Rat
leukocyte chemotaxis GO:0030595 22 0.014
regulation of proteolysis GO:0030162 66 0.014
sexual reproduction GO:0019953 148 0.014
Fly
positive regulation of cellular catabolic process GO:0031331 71 0.013
response to growth factor GO:0070848 189 0.013
Rat
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to toxic substance GO:0009636 133 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
rhythmic process GO:0048511 156 0.013
Mouse Rat
positive regulation of cell differentiation GO:0045597 217 0.013
Zebrafish Mouse
taxis GO:0042330 67 0.012
lymphocyte migration GO:0072676 3 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
vesicle mediated transport GO:0016192 181 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
cellular response to nutrient levels GO:0031669 60 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.012
Mouse
behavior GO:0007610 205 0.012
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.012
single organism catabolic process GO:0044712 283 0.012
response to fatty acid GO:0070542 65 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
Zebrafish Mouse Rat Fly
cellular component movement GO:0006928 248 0.012
Rat Fly
cellular response to metal ion GO:0071248 55 0.012
cellular response to interleukin 1 GO:0071347 37 0.012
monosaccharide metabolic process GO:0005996 61 0.012
regulation of anatomical structure size GO:0090066 135 0.012
protein heterooligomerization GO:0051291 89 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
Zebrafish Mouse Fly
positive regulation of transcription dna templated GO:0045893 197 0.012
Zebrafish Mouse Rat Fly
cellular response to reactive oxygen species GO:0034614 55 0.012
Rat
cellular metal ion homeostasis GO:0006875 172 0.011
cation homeostasis GO:0055080 195 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
Rat
cellular response to lipopolysaccharide GO:0071222 55 0.011
Fly
negative regulation of cell death GO:0060548 229 0.011
Mouse Rat
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
Rat
kidney development GO:0001822 67 0.011
Rat
immune system development GO:0002520 41 0.011
Zebrafish Mouse Fly
regulation of ion transport GO:0043269 245 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
mapk cascade GO:0000165 140 0.011
establishment of protein localization GO:0045184 141 0.011
connective tissue development GO:0061448 33 0.011
vascular process in circulatory system GO:0003018 96 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to insulin GO:0032868 133 0.011
Rat
cellular response to retinoic acid GO:0071300 27 0.011
negative regulation of signaling GO:0023057 157 0.011
Fly
circulatory system process GO:0003013 183 0.011
Rat
hepaticobiliary system development GO:0061008 90 0.011
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
salivary gland development GO:0007431 3 0.011
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.011
smooth muscle cell migration GO:0014909 36 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
sex differentiation GO:0007548 113 0.011
Mouse Rat
protein processing GO:0016485 68 0.011
cellular protein localization GO:0034613 122 0.011
regulation of anion transport GO:0044070 43 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
biological adhesion GO:0022610 110 0.011
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
Zebrafish Mouse Rat Fly
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
Rat
ribonucleotide catabolic process GO:0009261 136 0.010
peptidyl amino acid modification GO:0018193 126 0.010
Mouse
nuclear transport GO:0051169 49 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
Zebrafish Mouse Rat Fly
muscle cell migration GO:0014812 36 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
positive regulation of protein modification process GO:0031401 142 0.010
second messenger mediated signaling GO:0019932 51 0.010

Stat5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.025
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.014