Rattus norvegicus

53 known processes

Gucy2c

guanylate cyclase 2C

(Aliases: GCC)

Gucy2c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.215
regulation of nucleic acid templated transcription GO:1903506 380 0.210
regulation of transcription dna templated GO:0006355 374 0.143
cellular response to endogenous stimulus GO:0071495 377 0.143
rna metabolic process GO:0016070 406 0.120
regulation of phosphate metabolic process GO:0019220 349 0.111
regulation of rna metabolic process GO:0051252 391 0.097
monocarboxylic acid metabolic process GO:0032787 152 0.088
defecation GO:0030421 1 0.084
single organism reproductive process GO:0044702 297 0.083
oxoacid metabolic process GO:0043436 290 0.080
transcription dna templated GO:0006351 377 0.077
rna biosynthetic process GO:0032774 380 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.075
cellular catabolic process GO:0044248 295 0.074
nucleic acid templated transcription GO:0097659 379 0.069
g protein coupled receptor signaling pathway GO:0007186 242 0.063
organic substance catabolic process GO:1901575 316 0.060
reproductive process GO:0022414 372 0.058
regulation of rna biosynthetic process GO:2001141 381 0.057
asymmetric protein localization GO:0008105 2 0.052
carboxylic acid metabolic process GO:0019752 289 0.052
cellular component biogenesis GO:0044085 368 0.052
multi organism reproductive process GO:0044703 262 0.051
regulation of phosphorus metabolic process GO:0051174 349 0.048
rhythmic process GO:0048511 156 0.048
response to hypoxia GO:0001666 231 0.047
regulation of molecular function GO:0065009 398 0.046
organic anion transport GO:0015711 132 0.045
cellular macromolecule localization GO:0070727 122 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.044
catabolic process GO:0009056 351 0.043
reproductive structure development GO:0048608 128 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
multicellular organismal reproductive process GO:0048609 233 0.041
vitamin transport GO:0051180 14 0.039
reproduction GO:0000003 245 0.038
regulation of cell differentiation GO:0045595 320 0.037
small molecule biosynthetic process GO:0044283 124 0.036
positive regulation of molecular function GO:0044093 230 0.035
protein localization GO:0008104 191 0.035
developmental process involved in reproduction GO:0003006 159 0.034
immune system process GO:0002376 204 0.034
negative regulation of cell development GO:0010721 82 0.034
secretion GO:0046903 307 0.034
purine containing compound metabolic process GO:0072521 253 0.034
negative regulation of gene expression GO:0010629 199 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
positive regulation of protein metabolic process GO:0051247 178 0.032
negative regulation of nucleic acid templated transcription GO:1903507 117 0.032
single organism behavior GO:0044708 130 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
positive regulation of peptide hormone secretion GO:0090277 50 0.031
regulation of hydrolase activity GO:0051336 143 0.031
negative regulation of cell differentiation GO:0045596 99 0.030
regulation of catalytic activity GO:0050790 304 0.030
cellular component assembly GO:0022607 360 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
organic acid metabolic process GO:0006082 292 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
response to estrogen GO:0043627 232 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
ribonucleotide metabolic process GO:0009259 231 0.027
anion transport GO:0006820 178 0.027
cellular response to stress GO:0033554 269 0.027
single organism catabolic process GO:0044712 283 0.027
macromolecular complex assembly GO:0065003 273 0.026
positive regulation of peptide secretion GO:0002793 52 0.026
cellular cation homeostasis GO:0030003 180 0.025
positive regulation of signaling GO:0023056 270 0.025
sexual reproduction GO:0019953 148 0.025
tissue remodeling GO:0048771 40 0.025
secretion by cell GO:0032940 248 0.025
intracellular signal transduction GO:0035556 314 0.024
protein complex assembly GO:0006461 263 0.024
response to extracellular stimulus GO:0009991 380 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
regulation of membrane potential GO:0042391 110 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
aromatic compound catabolic process GO:0019439 168 0.024
response to nutrient levels GO:0031667 370 0.024
response to glucose GO:0009749 136 0.023
regulation of hormone levels GO:0010817 187 0.023
chemical homeostasis GO:0048878 292 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
response to decreased oxygen levels GO:0036293 237 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
organophosphate metabolic process GO:0019637 370 0.022
hormone metabolic process GO:0042445 69 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
protein phosphorylation GO:0006468 345 0.022
response to nutrient GO:0007584 248 0.022
regulation of catabolic process GO:0009894 113 0.022
response to cytokine GO:0034097 215 0.021
embryonic axis specification GO:0000578 1 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
bmp signaling pathway GO:0030509 4 0.021
nucleoside metabolic process GO:0009116 179 0.021
regulation of nervous system development GO:0051960 264 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
regulation of multicellular organismal development GO:2000026 376 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
regulation of protein metabolic process GO:0051246 289 0.020
axon development GO:0061564 96 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
heterocycle catabolic process GO:0046700 167 0.020
cell cell signaling GO:0007267 335 0.020
peptide hormone secretion GO:0030072 84 0.020
circadian rhythm GO:0007623 88 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.019
cellular response to gonadotropin stimulus GO:0071371 17 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
protein complex biogenesis GO:0070271 263 0.019
regulation of programmed cell death GO:0043067 341 0.019
negative regulation of nervous system development GO:0051961 79 0.019
negative regulation of molecular function GO:0044092 133 0.019
signal release GO:0023061 145 0.019
response to axon injury GO:0048678 59 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
regulation of system process GO:0044057 208 0.019
positive regulation of gene expression GO:0010628 244 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
protein tetramerization GO:0051262 38 0.018
regulation of immunoglobulin secretion GO:0051023 1 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
positive regulation of catabolic process GO:0009896 78 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
negative regulation of metabolic process GO:0009892 331 0.018
apoptotic process GO:0006915 381 0.018
regulation of phosphorylation GO:0042325 248 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
response to peptide GO:1901652 292 0.018
regulation of apoptotic process GO:0042981 335 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
nucleotide metabolic process GO:0009117 279 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
programmed cell death GO:0012501 392 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
regulation of cell development GO:0060284 263 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
cell cycle GO:0007049 101 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular ketone metabolic process GO:0042180 51 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
positive regulation of hormone secretion GO:0046887 65 0.016
purine containing compound catabolic process GO:0072523 138 0.016
neuron differentiation GO:0030182 368 0.016
negative regulation of organ growth GO:0046621 3 0.016
hepaticobiliary system development GO:0061008 90 0.016
gamete generation GO:0007276 124 0.016
response to amino acid GO:0043200 75 0.016
epithelium development GO:0060429 96 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
regulation of signal transduction GO:0009966 318 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
response to hexose GO:0009746 144 0.015
nitrogen compound transport GO:0071705 229 0.015
regulation of immunoglobulin mediated immune response GO:0002889 2 0.015
multicellular organism reproduction GO:0032504 233 0.015
neurological system process GO:0050877 219 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
multicellular organism growth GO:0035264 1 0.015
regulation of peptide transport GO:0090087 87 0.015
circulatory system process GO:0003013 183 0.015
amine metabolic process GO:0009308 38 0.015
reproductive system development GO:0061458 128 0.014
response to carbohydrate GO:0009743 183 0.014
positive regulation of cell communication GO:0010647 271 0.014
adult locomotory behavior GO:0008344 4 0.014
spermatogenesis GO:0007283 99 0.014
cellular amine metabolic process GO:0044106 38 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.014
phosphatidylinositol dephosphorylation GO:0046856 4 0.014
exploration behavior GO:0035640 1 0.014
response to growth factor GO:0070848 189 0.014
biological adhesion GO:0022610 110 0.014
circulatory system development GO:0072359 134 0.014
positive regulation of gtpase activity GO:0043547 47 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
gonad development GO:0008406 104 0.014
protein oligomerization GO:0051259 191 0.014
protein heterooligomerization GO:0051291 89 0.013
regulation of hormone secretion GO:0046883 106 0.013
axis specification GO:0009798 4 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
lipid metabolic process GO:0006629 283 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
response to estradiol GO:0032355 164 0.013
locomotory behavior GO:0007626 15 0.013
response to testosterone GO:0033574 55 0.013
anterior posterior pattern specification GO:0009952 1 0.013
negative regulation of developmental process GO:0051093 125 0.013
heart development GO:0007507 72 0.013
positive regulation of immunoglobulin production GO:0002639 4 0.013
neuronal action potential GO:0019228 35 0.013
heart morphogenesis GO:0003007 3 0.013
hormone transport GO:0009914 121 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
response to wounding GO:0009611 254 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
response to monosaccharide GO:0034284 159 0.012
cell type specific apoptotic process GO:0097285 134 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
mesoderm development GO:0007498 2 0.012
cell adhesion GO:0007155 110 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of peptide secretion GO:0002791 82 0.012
carbohydrate metabolic process GO:0005975 130 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
skeletal system development GO:0001501 41 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
negative regulation of signal transduction GO:0009968 83 0.012
positive regulation of blood circulation GO:1903524 65 0.012
positive regulation of isotype switching GO:0045830 1 0.012
synaptic transmission glycinergic GO:0060012 2 0.012
lipid biosynthetic process GO:0008610 128 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.011
regulation of neurogenesis GO:0050767 247 0.011
dephosphorylation GO:0016311 98 0.011
protein complex subunit organization GO:0071822 302 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
regulation of insulin secretion GO:0050796 65 0.011
cell activation GO:0001775 97 0.011
neuron projection development GO:0031175 273 0.011
brown fat cell proliferation GO:0070342 2 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.011
sensory perception of pain GO:0019233 73 0.011
neuroblast differentiation GO:0014016 1 0.011
positive regulation of insulin secretion GO:0032024 36 0.011
single organism biosynthetic process GO:0044711 342 0.011
positive regulation of cell development GO:0010720 176 0.011
negative regulation of signaling GO:0023057 157 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regeneration GO:0031099 163 0.011
hormone secretion GO:0046879 115 0.011
pyruvate metabolic process GO:0006090 27 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
response to light stimulus GO:0009416 52 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
positive regulation of transport GO:0051050 245 0.010
protein transport GO:0015031 132 0.010
positive regulation of developmental process GO:0051094 283 0.010
organophosphate catabolic process GO:0046434 148 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
lipid storage GO:0019915 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
ribonucleoside metabolic process GO:0009119 174 0.010

Gucy2c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.049
inherited metabolic disorder DOID:655 0 0.049
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of cellular proliferation DOID:14566 0 0.012