Rattus norvegicus

0 known processes

Gucy2g

guanylate cyclase 2G

(Aliases: ksGC)

Gucy2g biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.565
regulation of rna metabolic process GO:0051252 391 0.370
nucleic acid templated transcription GO:0097659 379 0.352
transcription from rna polymerase ii promoter GO:0006366 252 0.282
positive regulation of cellular biosynthetic process GO:0031328 295 0.262
Rat
transcription dna templated GO:0006351 377 0.248
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.225
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.219
regulation of transcription dna templated GO:0006355 374 0.216
positive regulation of gene expression GO:0010628 244 0.189
positive regulation of biosynthetic process GO:0009891 319 0.189
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.177
Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.177
Rat
single organism biosynthetic process GO:0044711 342 0.156
Mouse Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.155
cellular component movement GO:0006928 248 0.145
rna biosynthetic process GO:0032774 380 0.143
positive regulation of transcription dna templated GO:0045893 197 0.140
ribose phosphate biosynthetic process GO:0046390 87 0.128
Mouse Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.122
homeostatic process GO:0042592 331 0.117
positive regulation of rna metabolic process GO:0051254 203 0.116
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.106
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.105
single organism reproductive process GO:0044702 297 0.103
organophosphate metabolic process GO:0019637 370 0.098
Mouse Rat
regulation of locomotion GO:0040012 148 0.098
negative regulation of nucleic acid templated transcription GO:1903507 117 0.094
regulation of rna biosynthetic process GO:2001141 381 0.093
negative regulation of vesicle fusion GO:0031339 2 0.087
rna metabolic process GO:0016070 406 0.086
purine containing compound biosynthetic process GO:0072522 85 0.086
Mouse Rat
reproduction GO:0000003 245 0.078
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.077
neurological system process GO:0050877 219 0.073
carbohydrate metabolic process GO:0005975 130 0.073
anion transport GO:0006820 178 0.072
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.072
response to nutrient GO:0007584 248 0.070
regulation of apoptotic process GO:0042981 335 0.070
negative regulation of cell death GO:0060548 229 0.070
cellular response to stress GO:0033554 269 0.070
divalent inorganic cation homeostasis GO:0072507 165 0.069
regulation of system process GO:0044057 208 0.068
nucleotide biosynthetic process GO:0009165 98 0.065
Mouse Rat
multicellular organismal reproductive process GO:0048609 233 0.065
positive regulation of cell communication GO:0010647 271 0.064
hormone transport GO:0009914 121 0.064
regulation of phosphate metabolic process GO:0019220 349 0.062
Rat
negative regulation of response to tumor cell GO:0002835 2 0.059
cellular calcium ion homeostasis GO:0006874 160 0.058
macromolecule localization GO:0033036 252 0.058
vesicle mediated transport GO:0016192 181 0.056
purine ribonucleotide biosynthetic process GO:0009152 81 0.056
Mouse Rat
regulation of cell development GO:0060284 263 0.055
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.054
negative regulation of rna metabolic process GO:0051253 123 0.054
ribonucleotide metabolic process GO:0009259 231 0.054
Mouse Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.053
Rat
cell cell signaling GO:0007267 335 0.053
negative regulation of metabolic process GO:0009892 331 0.052
regulation of cell differentiation GO:0045595 320 0.052
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.051
negative regulation of rna biosynthetic process GO:1902679 118 0.051
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.051
single organism organelle organization GO:1902589 180 0.051
macromolecular complex subunit organization GO:0043933 339 0.050
cell motility GO:0048870 202 0.050
epithelium development GO:0060429 96 0.050
apoptotic process GO:0006915 381 0.049
cytosolic calcium ion homeostasis GO:0051480 140 0.048
negative regulation of apoptotic process GO:0043066 181 0.048
regulation of phosphorylation GO:0042325 248 0.047
protein complex subunit organization GO:0071822 302 0.047
carbohydrate derivative metabolic process GO:1901135 346 0.046
Mouse Rat
cardiac muscle contraction GO:0060048 27 0.046
carbohydrate derivative biosynthetic process GO:1901137 124 0.046
Mouse Rat
hormone secretion GO:0046879 115 0.046
purine nucleotide metabolic process GO:0006163 229 0.046
Mouse Rat
regulation of signal transduction GO:0009966 318 0.046
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.046
immune response GO:0006955 104 0.045
regulation of immune response to tumor cell GO:0002837 3 0.044
programmed cell death GO:0012501 392 0.043
negative regulation of neurogenesis GO:0050768 78 0.042
regulation of growth GO:0040008 105 0.042
response to nutrient levels GO:0031667 370 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
regulation of immune system process GO:0002682 123 0.041
brain development GO:0007420 247 0.041
regulation of cell proliferation GO:0042127 359 0.041
Rat
intracellular signal transduction GO:0035556 314 0.041
Rat
cellular homeostasis GO:0019725 252 0.040
response to mechanical stimulus GO:0009612 134 0.040
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.040
Rat
protein localization GO:0008104 191 0.040
regulation of hormone secretion GO:0046883 106 0.039
cellular ion homeostasis GO:0006873 184 0.039
organophosphate biosynthetic process GO:0090407 143 0.039
Mouse Rat
regulation of programmed cell death GO:0043067 341 0.039
membrane organization GO:0061024 94 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.039
positive regulation of signaling GO:0023056 270 0.039
metal ion homeostasis GO:0055065 186 0.038
positive regulation of cell migration GO:0030335 96 0.038
regulation of nucleotide biosynthetic process GO:0030808 47 0.037
Rat
neuron differentiation GO:0030182 368 0.037
negative regulation of cell development GO:0010721 82 0.037
purine nucleotide biosynthetic process GO:0006164 83 0.037
Mouse Rat
cation homeostasis GO:0055080 195 0.036
negative regulation of biosynthetic process GO:0009890 168 0.036
cellular response to insulin stimulus GO:0032869 81 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
regulation of vesicle mediated transport GO:0060627 81 0.035
cyclic nucleotide biosynthetic process GO:0009190 63 0.034
Mouse Rat
negative regulation of immune response to tumor cell GO:0002838 2 0.034
regulation of nucleotide metabolic process GO:0006140 117 0.034
Rat
negative regulation of cell differentiation GO:0045596 99 0.033
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.033
Rat
regulation of cellular localization GO:0060341 263 0.031
rhythmic process GO:0048511 156 0.030
inflammatory response GO:0006954 150 0.030
anion transmembrane transport GO:0098656 77 0.030
circulatory system process GO:0003013 183 0.030
smooth muscle cell proliferation GO:0048659 77 0.029
Rat
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.029
Mouse Rat
response to wounding GO:0009611 254 0.028
central nervous system development GO:0007417 311 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.028
cell migration GO:0016477 197 0.028
sensory perception GO:0007600 101 0.028
cellular component biogenesis GO:0044085 368 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.027
nucleotide metabolic process GO:0009117 279 0.027
Mouse Rat
chemotaxis GO:0006935 66 0.027
regulation of intracellular signal transduction GO:1902531 218 0.027
immune system process GO:0002376 204 0.026
cyclic nucleotide metabolic process GO:0009187 80 0.026
Mouse Rat
multicellular organism growth GO:0035264 1 0.026
monocarboxylic acid transport GO:0015718 52 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
ion homeostasis GO:0050801 212 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
Mouse Rat
positive regulation of apoptotic process GO:0043065 154 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
secretion GO:0046903 307 0.026
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.025
response to hypoxia GO:0001666 231 0.025
ossification GO:0001503 70 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
Mouse Rat
ribonucleotide biosynthetic process GO:0009260 85 0.024
Mouse Rat
regulation of secretion by cell GO:1903530 208 0.024
carboxylic acid catabolic process GO:0046395 49 0.024
multicellular organism reproduction GO:0032504 233 0.024
macromolecular complex assembly GO:0065003 273 0.024
localization of cell GO:0051674 202 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
axis specification GO:0009798 4 0.023
response to growth factor GO:0070848 189 0.023
learning or memory GO:0007611 90 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
camp metabolic process GO:0046058 63 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
secretion by cell GO:0032940 248 0.023
regulation of blood circulation GO:1903522 110 0.023
circadian rhythm GO:0007623 88 0.023
eye morphogenesis GO:0048592 4 0.023
positive regulation of protein modification process GO:0031401 142 0.022
detection of calcium ion GO:0005513 1 0.022
cyclic purine nucleotide metabolic process GO:0052652 62 0.022
Mouse Rat
response to extracellular stimulus GO:0009991 380 0.022
reproductive process GO:0022414 372 0.022
positive regulation of locomotion GO:0040017 102 0.022
regulation of camp metabolic process GO:0030814 43 0.022
cognition GO:0050890 92 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
organelle organization GO:0006996 266 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
protein complex assembly GO:0006461 263 0.022
regulation of kinase activity GO:0043549 117 0.021
protein complex biogenesis GO:0070271 263 0.021
chemical homeostasis GO:0048878 292 0.021
head development GO:0060322 247 0.021
regulation of camp biosynthetic process GO:0030817 38 0.021
regulation of nervous system development GO:0051960 264 0.021
regulation of cell motility GO:2000145 131 0.021
regulation of insulin secretion GO:0050796 65 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
regulation of neurogenesis GO:0050767 247 0.020
negative regulation of nervous system development GO:0051961 79 0.020
organ morphogenesis GO:0009887 75 0.020
regulation of cellular component movement GO:0051270 150 0.020
inner ear morphogenesis GO:0042472 1 0.019
regulation of molecular function GO:0065009 398 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.019
Rat
regulation of hormone levels GO:0010817 187 0.019
sexual reproduction GO:0019953 148 0.019
response to decreased oxygen levels GO:0036293 237 0.019
positive regulation of developmental process GO:0051094 283 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
leukocyte cell cell adhesion GO:0007159 4 0.019
response to biotic stimulus GO:0009607 226 0.019
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
multi organism reproductive process GO:0044703 262 0.019
regulation of organelle organization GO:0033043 80 0.019
calcium ion homeostasis GO:0055074 162 0.018
negative regulation of developmental process GO:0051093 125 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
cellular cation homeostasis GO:0030003 180 0.018
blood circulation GO:0008015 183 0.018
response to antibiotic GO:0046677 39 0.018
glial cell differentiation GO:0010001 65 0.018
retina morphogenesis in camera type eye GO:0060042 1 0.018
intracellular transport GO:0046907 185 0.018
cellular component assembly GO:0022607 360 0.018
response to light stimulus GO:0009416 52 0.018
response to retinoic acid GO:0032526 63 0.018
regulation of cell migration GO:0030334 128 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
defense response GO:0006952 194 0.018
signal release GO:0023061 145 0.018
nitrogen compound transport GO:0071705 229 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
aging GO:0007568 241 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
camp biosynthetic process GO:0006171 47 0.017
regulation of neuron differentiation GO:0045664 208 0.017
sensory organ development GO:0007423 74 0.017
positive regulation of hormone secretion GO:0046887 65 0.017
cell projection organization GO:0030030 302 0.017
detection of stimulus GO:0051606 24 0.017
organic anion transport GO:0015711 132 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
embryonic skeletal system morphogenesis GO:0048704 3 0.016
locomotion GO:0040011 237 0.016
catabolic process GO:0009056 351 0.016
single organism behavior GO:0044708 130 0.016
positive regulation of molecular function GO:0044093 230 0.016
peptide secretion GO:0002790 86 0.016
behavior GO:0007610 205 0.016
s shaped body morphogenesis GO:0072050 2 0.016
regulation of response to tumor cell GO:0002834 3 0.016
endoplasmic reticulum organization GO:0007029 1 0.016
neuron projection development GO:0031175 273 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
camera type eye morphogenesis GO:0048593 2 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
innate immune response GO:0045087 35 0.016
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.016
Rat
positive regulation of cell development GO:0010720 176 0.015
regulation of homeostatic process GO:0032844 101 0.015
response to monosaccharide GO:0034284 159 0.015
positive regulation of transport GO:0051050 245 0.015
nucleoside monophosphate metabolic process GO:0009123 93 0.015
positive regulation of cell motility GO:2000147 97 0.015
spermatogenesis GO:0007283 99 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
embryonic skeletal system development GO:0048706 3 0.015
response to ethanol GO:0045471 162 0.015
cellular protein localization GO:0034613 122 0.015
positive regulation of secretion GO:0051047 140 0.015
neuron development GO:0048666 286 0.015
synaptic transmission GO:0007268 235 0.015
response to cytokine GO:0034097 215 0.015
regulation of catalytic activity GO:0050790 304 0.015
negative regulation of gene expression GO:0010629 199 0.015
adult locomotory behavior GO:0008344 4 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
cellular response to growth factor stimulus GO:0071363 162 0.014
cation transport GO:0006812 382 0.014
negative regulation of innate immune response GO:0045824 4 0.014
response to oxygen levels GO:0070482 265 0.014
cation transmembrane transport GO:0098655 263 0.014
cell cycle GO:0007049 101 0.014
male gamete generation GO:0048232 99 0.014
bmp signaling pathway GO:0030509 4 0.014
single organism catabolic process GO:0044712 283 0.014
response to radiation GO:0009314 137 0.014
response to external biotic stimulus GO:0043207 221 0.014
exocytosis GO:0006887 60 0.013
cell activation GO:0001775 97 0.013
growth GO:0040007 165 0.013
response to other organism GO:0051707 220 0.013
regulation of anatomical structure size GO:0090066 135 0.013
purine containing compound metabolic process GO:0072521 253 0.013
Mouse Rat
fatty acid beta oxidation GO:0006635 22 0.013
regulation of protein kinase activity GO:0045859 105 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
protein autophosphorylation GO:0046777 66 0.013
establishment of anatomical structure orientation GO:0048560 1 0.013
immune response to tumor cell GO:0002418 3 0.013
regulation of peptide secretion GO:0002791 82 0.013
tube development GO:0035295 89 0.013
response to oxidative stress GO:0006979 186 0.013
response to acid chemical GO:0001101 222 0.013
establishment of protein localization GO:0045184 141 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
positive regulation of signal transduction GO:0009967 175 0.013
organic acid transport GO:0015849 116 0.013
leukocyte activation GO:0045321 76 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.012
peptide transport GO:0015833 97 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
insulin secretion GO:0030073 69 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
regulation of carbohydrate metabolic process GO:0006109 41 0.012
response to reactive oxygen species GO:0000302 120 0.012
inositol trisphosphate biosynthetic process GO:0032959 3 0.012
jak stat cascade GO:0007259 26 0.012
negative regulation of secretion GO:0051048 82 0.012
response to insulin GO:0032868 133 0.012
single organism intracellular transport GO:1902582 166 0.012
gastrulation GO:0007369 2 0.012
cell differentiation involved in kidney development GO:0061005 4 0.012
response to glucose GO:0009749 136 0.012
response to peptide hormone GO:0043434 278 0.012
positive regulation of organelle organization GO:0010638 48 0.012
calcium ion import GO:0070509 22 0.012
regulation of neurotransmitter levels GO:0001505 42 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
lipid metabolic process GO:0006629 283 0.012
cellular ketone metabolic process GO:0042180 51 0.012
regulation of peptide transport GO:0090087 87 0.012
olfactory behavior GO:0042048 2 0.012
memory GO:0007613 54 0.012
organ regeneration GO:0031100 101 0.011
positive regulation of nervous system development GO:0051962 178 0.011
cellular catabolic process GO:0044248 295 0.011
heart process GO:0003015 57 0.011
fertilization GO:0009566 3 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
actin filament organization GO:0007015 42 0.011
regeneration GO:0031099 163 0.011
ear development GO:0043583 21 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
regulation of protein metabolic process GO:0051246 289 0.011
ovulation cycle GO:0042698 67 0.011
regulation of transferase activity GO:0051338 123 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of neuron projection development GO:0010975 161 0.011
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.011
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
renal system development GO:0072001 67 0.011
sequestering of calcium ion GO:0051208 8 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
chemosensory behavior GO:0007635 2 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
regulation of response to external stimulus GO:0032101 106 0.011
actin mediated cell contraction GO:0070252 12 0.011
cellular response to peptide GO:1901653 133 0.011
acetyl coa metabolic process GO:0006084 17 0.011
cardiac muscle cell contraction GO:0086003 10 0.011
gliogenesis GO:0042063 93 0.011
protein oligomerization GO:0051259 191 0.011
negative regulation of response to biotic stimulus GO:0002832 4 0.011
cellular lipid metabolic process GO:0044255 208 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of muscle system process GO:0090257 79 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
cellular amine metabolic process GO:0044106 38 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
Mouse Rat
cytoplasmic transport GO:0016482 115 0.010
maintenance of location GO:0051235 17 0.010
cellular chemical homeostasis GO:0055082 247 0.010
response to electrical stimulus GO:0051602 56 0.010
response to tumor cell GO:0002347 4 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
transmembrane transport GO:0055085 412 0.010
negative regulation of osteoblast differentiation GO:0045668 2 0.010
response to increased oxygen levels GO:0036296 45 0.010
regulation of cyclase activity GO:0031279 21 0.010
cell morphogenesis GO:0000902 142 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010

Gucy2g disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
muscular disease DOID:0080000 0 0.028
musculoskeletal system disease DOID:17 0 0.028
muscle tissue disease DOID:66 0 0.028
sensory system disease DOID:0050155 0 0.025
eye and adnexa disease DOID:1492 0 0.018
myopathy DOID:423 0 0.015
cardiovascular system disease DOID:1287 0 0.014
eye disease DOID:5614 0 0.013
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
retinitis pigmentosa DOID:10584 0 0.011
heart disease DOID:114 0 0.011
cardiomyopathy DOID:0050700 0 0.011