Rattus norvegicus

0 known processes

Fgd5

FYVE, RhoGEF and PH domain containing 5

Fgd5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organophosphate metabolic process GO:0019637 370 0.171
positive regulation of phosphorus metabolic process GO:0010562 262 0.096
cellular component assembly GO:0022607 360 0.093
regulation of phosphate metabolic process GO:0019220 349 0.089
regulation of phosphorus metabolic process GO:0051174 349 0.086
cellular component biogenesis GO:0044085 368 0.081
carbohydrate derivative metabolic process GO:1901135 346 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.074
programmed cell death GO:0012501 392 0.074
lipid metabolic process GO:0006629 283 0.073
nucleobase containing small molecule metabolic process GO:0055086 316 0.072
intracellular signal transduction GO:0035556 314 0.072
ribonucleotide metabolic process GO:0009259 231 0.071
regulation of intracellular signal transduction GO:1902531 218 0.069
positive regulation of lipid kinase activity GO:0090218 2 0.068
protein phosphorylation GO:0006468 345 0.066
nucleoside phosphate metabolic process GO:0006753 283 0.066
positive regulation of regulatory t cell differentiation GO:0045591 2 0.065
regulation of signal transduction GO:0009966 318 0.062
calcium ion homeostasis GO:0055074 162 0.061
response to wounding GO:0009611 254 0.060
response to peptide hormone GO:0043434 278 0.058
regulation of cellular protein metabolic process GO:0032268 267 0.058
cellular metal ion homeostasis GO:0006875 172 0.057
single organism catabolic process GO:0044712 283 0.056
regulation of catalytic activity GO:0050790 304 0.056
negative regulation of metabolic process GO:0009892 331 0.055
vasculature development GO:0001944 70 0.054
localization of cell GO:0051674 202 0.054
regeneration GO:0031099 163 0.052
regulation of multicellular organismal development GO:2000026 376 0.052
wound healing GO:0042060 122 0.051
response to nutrient levels GO:0031667 370 0.051
positive regulation of biosynthetic process GO:0009891 319 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.050
regulation of molecular function GO:0065009 398 0.049
regulation of apoptotic process GO:0042981 335 0.049
protein complex assembly GO:0006461 263 0.049
cell motility GO:0048870 202 0.049
purine containing compound metabolic process GO:0072521 253 0.049
ribose phosphate metabolic process GO:0019693 235 0.048
response to growth factor GO:0070848 189 0.048
regulation of phosphorylation GO:0042325 248 0.048
positive regulation of protein phosphorylation GO:0001934 135 0.048
positive regulation of phosphate metabolic process GO:0045937 262 0.047
positive regulation of catalytic activity GO:0043085 184 0.046
regulation of programmed cell death GO:0043067 341 0.045
positive regulation of molecular function GO:0044093 230 0.045
macromolecular complex subunit organization GO:0043933 339 0.045
response to peptide GO:1901652 292 0.044
regulation of cellular component movement GO:0051270 150 0.044
cellular divalent inorganic cation homeostasis GO:0072503 162 0.044
protein complex biogenesis GO:0070271 263 0.044
cellular cation homeostasis GO:0030003 180 0.044
nucleoside catabolic process GO:0009164 126 0.043
rna biosynthetic process GO:0032774 380 0.042
purine nucleotide metabolic process GO:0006163 229 0.042
cytosolic calcium ion homeostasis GO:0051480 140 0.042
regulation of cell proliferation GO:0042127 359 0.042
locomotion GO:0040011 237 0.041
cellular chemical homeostasis GO:0055082 247 0.041
positive regulation of response to stimulus GO:0048584 285 0.040
regulation of cell differentiation GO:0045595 320 0.040
positive regulation of protein metabolic process GO:0051247 178 0.039
cellular calcium ion homeostasis GO:0006874 160 0.039
positive regulation of signal transduction GO:0009967 175 0.039
regulation of locomotion GO:0040012 148 0.038
positive regulation of intracellular signal transduction GO:1902533 138 0.038
signal transduction by phosphorylation GO:0023014 144 0.037
response to extracellular stimulus GO:0009991 380 0.037
immune system process GO:0002376 204 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.037
circulatory system development GO:0072359 134 0.037
response to estrogen GO:0043627 232 0.037
ras protein signal transduction GO:0007265 29 0.037
regulation of cellular component organization GO:0051128 368 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.036
purine nucleotide catabolic process GO:0006195 136 0.036
cellular response to growth factor stimulus GO:0071363 162 0.035
nucleoside triphosphate catabolic process GO:0009143 123 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
defense response GO:0006952 194 0.035
glycosyl compound metabolic process GO:1901657 182 0.035
ion homeostasis GO:0050801 212 0.034
small gtpase mediated signal transduction GO:0007264 36 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.034
macromolecular complex assembly GO:0065003 273 0.034
purine nucleoside metabolic process GO:0042278 169 0.034
blood vessel development GO:0001568 69 0.034
cation homeostasis GO:0055080 195 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
apoptotic process GO:0006915 381 0.033
positive regulation of signaling GO:0023056 270 0.033
blood vessel morphogenesis GO:0048514 58 0.033
cellular ion homeostasis GO:0006873 184 0.033
cellular amine metabolic process GO:0044106 38 0.033
divalent inorganic cation homeostasis GO:0072507 165 0.032
cell projection organization GO:0030030 302 0.032
negative regulation of programmed cell death GO:0043069 183 0.032
metal ion homeostasis GO:0055065 186 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
purine containing compound catabolic process GO:0072523 138 0.032
regulation of immune system process GO:0002682 123 0.032
nucleotide metabolic process GO:0009117 279 0.032
positive regulation of cellular protein metabolic process GO:0032270 167 0.031
purine nucleoside triphosphate catabolic process GO:0009146 122 0.031
nucleoside metabolic process GO:0009116 179 0.031
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
chemical homeostasis GO:0048878 292 0.030
rna metabolic process GO:0016070 406 0.030
cardiovascular system development GO:0072358 134 0.030
organic substance catabolic process GO:1901575 316 0.029
positive regulation of gene expression GO:0010628 244 0.029
catabolic process GO:0009056 351 0.029
regulation of cell motility GO:2000145 131 0.029
regulation of protein metabolic process GO:0051246 289 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
aromatic compound catabolic process GO:0019439 168 0.028
vasculogenesis GO:0001570 3 0.028
purine ribonucleotide catabolic process GO:0009154 136 0.028
protein complex subunit organization GO:0071822 302 0.028
anatomical structure formation involved in morphogenesis GO:0048646 83 0.028
cellular response to oxygen containing compound GO:1901701 386 0.027
regulation of hydrolase activity GO:0051336 143 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
transcription dna templated GO:0006351 377 0.027
leukocyte activation GO:0045321 76 0.027
amine metabolic process GO:0009308 38 0.027
cellular component morphogenesis GO:0032989 155 0.027
neurological system process GO:0050877 219 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
cellular component movement GO:0006928 248 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
positive regulation of developmental process GO:0051094 283 0.025
positive regulation of mapk cascade GO:0043410 92 0.025
positive regulation of protein modification process GO:0031401 142 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
cellular response to hormone stimulus GO:0032870 247 0.025
guanosine containing compound catabolic process GO:1901069 71 0.025
embryonic pattern specification GO:0009880 1 0.025
ribonucleotide catabolic process GO:0009261 136 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
mapk cascade GO:0000165 140 0.024
nucleobase containing compound catabolic process GO:0034655 152 0.024
nucleotide catabolic process GO:0009166 139 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.024
regulation of protein modification process GO:0031399 194 0.024
organelle organization GO:0006996 266 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
protein autophosphorylation GO:0046777 66 0.024
negative regulation of cell death GO:0060548 229 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
multicellular organism reproduction GO:0032504 233 0.024
protein oligomerization GO:0051259 191 0.024
glycosyl compound catabolic process GO:1901658 126 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
ribonucleoside triphosphate catabolic process GO:0009203 122 0.023
metal ion transport GO:0030001 289 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
positive regulation of cell communication GO:0010647 271 0.023
negative regulation of developmental process GO:0051093 125 0.023
regulation of mapk cascade GO:0043408 116 0.023
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
tissue development GO:0009888 252 0.022
neuron differentiation GO:0030182 368 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
regulation of catabolic process GO:0009894 113 0.022
regulation of transcription dna templated GO:0006355 374 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
regulation of rna biosynthetic process GO:2001141 381 0.021
cellular lipid metabolic process GO:0044255 208 0.021
central nervous system development GO:0007417 311 0.021
response to oxygen levels GO:0070482 265 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
regulation of membrane potential GO:0042391 110 0.021
calcium ion transport GO:0006816 131 0.021
biological adhesion GO:0022610 110 0.021
single organism biosynthetic process GO:0044711 342 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
regulation of cell development GO:0060284 263 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
brain development GO:0007420 247 0.021
regulation of cell migration GO:0030334 128 0.021
multicellular organismal homeostasis GO:0048871 49 0.021
divalent inorganic cation transport GO:0072511 134 0.020
heterocycle catabolic process GO:0046700 167 0.020
regulation of response to stress GO:0080134 126 0.020
organic acid metabolic process GO:0006082 292 0.020
response to decreased oxygen levels GO:0036293 237 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
cell morphogenesis GO:0000902 142 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
regulation of transferase activity GO:0051338 123 0.019
cellular ketone metabolic process GO:0042180 51 0.019
homeostatic process GO:0042592 331 0.019
cellular homeostasis GO:0019725 252 0.019
actin filament based process GO:0030029 86 0.019
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
immune response GO:0006955 104 0.018
growth GO:0040007 165 0.018
response to carbohydrate GO:0009743 183 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of kinase activity GO:0043549 117 0.018
negative regulation of innate immune response GO:0045824 4 0.018
secretion GO:0046903 307 0.018
regulation of ras gtpase activity GO:0032318 32 0.018
gliogenesis GO:0042063 93 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
negative regulation of cell communication GO:0010648 158 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
positive regulation of defense response GO:0031349 37 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
angiogenesis GO:0001525 53 0.018
regulation of ras protein signal transduction GO:0046578 45 0.018
cell substrate adhesion GO:0031589 29 0.018
cell cell signaling GO:0007267 335 0.017
regulation of ion transport GO:0043269 245 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
neuron projection development GO:0031175 273 0.017
nucleic acid templated transcription GO:0097659 379 0.017
rho protein signal transduction GO:0007266 11 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
negative regulation of signaling GO:0023057 157 0.017
positive regulation of endothelial cell migration GO:0010595 4 0.017
peptidyl amino acid modification GO:0018193 126 0.017
axis specification GO:0009798 4 0.017
muscle cell proliferation GO:0033002 84 0.017
cellular catabolic process GO:0044248 295 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
regulation of nucleotide catabolic process GO:0030811 65 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
oxoacid metabolic process GO:0043436 290 0.017
gland development GO:0048732 155 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
regulation of hormone levels GO:0010817 187 0.017
behavior GO:0007610 205 0.017
response to nutrient GO:0007584 248 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
erk1 and erk2 cascade GO:0070371 48 0.017
single organism organelle organization GO:1902589 180 0.017
positive regulation of neuron differentiation GO:0045666 126 0.016
cation transport GO:0006812 382 0.016
regulation of cellular localization GO:0060341 263 0.016
regulation of gtpase activity GO:0043087 57 0.016
positive regulation of nervous system development GO:0051962 178 0.016
single organism reproductive process GO:0044702 297 0.016
response to cytokine GO:0034097 215 0.016
macromolecule localization GO:0033036 252 0.016
aging GO:0007568 241 0.016
developmental growth GO:0048589 100 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
head development GO:0060322 247 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
response to ketone GO:1901654 182 0.016
regulation of angiogenesis GO:0045765 39 0.016
transmembrane transport GO:0055085 412 0.016
reproduction GO:0000003 245 0.015
endochondral ossification GO:0001958 2 0.015
cytoskeleton organization GO:0007010 111 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
forebrain development GO:0030900 98 0.015
negative regulation of molecular function GO:0044092 133 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of nervous system development GO:0051960 264 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
cell activation GO:0001775 97 0.015
organophosphate catabolic process GO:0046434 148 0.015
divalent metal ion transport GO:0070838 132 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
regulation of neurogenesis GO:0050767 247 0.015
neuronal action potential GO:0019228 35 0.015
negative regulation of gene expression GO:0010629 199 0.015
phospholipid metabolic process GO:0006644 61 0.015
sexual reproduction GO:0019953 148 0.015
action potential GO:0001508 54 0.015
reproductive process GO:0022414 372 0.015
regulation of stem cell differentiation GO:2000736 2 0.015
urogenital system development GO:0001655 78 0.015
cell migration GO:0016477 197 0.015
regulation of system process GO:0044057 208 0.015
noradrenergic neuron differentiation GO:0003357 1 0.015
secretion by cell GO:0032940 248 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
positive regulation of locomotion GO:0040017 102 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
single organism cell adhesion GO:0098602 46 0.014
neuron apoptotic process GO:0051402 88 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
anterior posterior pattern specification GO:0009952 1 0.014
cell junction organization GO:0034330 21 0.014
neuron development GO:0048666 286 0.014
positive regulation of immune system process GO:0002684 90 0.014
positive regulation of cell motility GO:2000147 97 0.014
positive regulation of catabolic process GO:0009896 78 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
actin cytoskeleton organization GO:0030036 73 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
response to vitamin GO:0033273 131 0.014
positive regulation of kinase activity GO:0033674 77 0.014
regulation of anatomical structure size GO:0090066 135 0.013
response to oxidative stress GO:0006979 186 0.013
gtp metabolic process GO:0046039 72 0.013
neuron death GO:0070997 127 0.013
gastrulation GO:0007369 2 0.013
gtp catabolic process GO:0006184 71 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
cellular response to stress GO:0033554 269 0.013
skeletal system development GO:0001501 41 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
positive regulation of cell death GO:0010942 184 0.013
response to bacterium GO:0009617 200 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
nitrogen compound transport GO:0071705 229 0.013
response to inorganic substance GO:0010035 377 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
positive regulation of ras gtpase activity GO:0032320 28 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of neuron death GO:1901214 115 0.012
dna metabolic process GO:0006259 96 0.012
cell matrix adhesion GO:0007160 19 0.012
glial cell differentiation GO:0010001 65 0.012
cell adhesion GO:0007155 110 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
salivary gland development GO:0007431 3 0.012
response to hypoxia GO:0001666 231 0.012
organ morphogenesis GO:0009887 75 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
positive regulation of gtpase activity GO:0043547 47 0.012
transmission of nerve impulse GO:0019226 42 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
carbohydrate metabolic process GO:0005975 130 0.012
negative regulation of transport GO:0051051 136 0.012
response to monosaccharide GO:0034284 159 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of rna metabolic process GO:0051252 391 0.012
response to lipopolysaccharide GO:0032496 191 0.012
response to acid chemical GO:0001101 222 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of cytokine biosynthetic process GO:0042035 3 0.012
reproductive system development GO:0061458 128 0.012
reproductive structure development GO:0048608 128 0.012
vesicle mediated transport GO:0016192 181 0.012
neural crest cell differentiation GO:0014033 2 0.012
inflammatory response GO:0006954 150 0.012
regulation of neuron differentiation GO:0045664 208 0.012
response to organophosphorus GO:0046683 102 0.012
cytokine production GO:0001816 61 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
response to external biotic stimulus GO:0043207 221 0.012
regulation of response to external stimulus GO:0032101 106 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.011
cytokine biosynthetic process GO:0042089 3 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
blood circulation GO:0008015 183 0.011
cell part morphogenesis GO:0032990 123 0.011
membrane organization GO:0061024 94 0.011
protein heterooligomerization GO:0051291 89 0.011
regulation of defense response GO:0031347 68 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
heart development GO:0007507 72 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
limb morphogenesis GO:0035108 4 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
response to radiation GO:0009314 137 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
regulation of actin cytoskeleton organization GO:0032956 30 0.011
regulation of vasculature development GO:1901342 44 0.011
lymphocyte homeostasis GO:0002260 2 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of cell migration GO:0030335 96 0.011
positive regulation of angiogenesis GO:0045766 28 0.011
multicellular organismal signaling GO:0035637 44 0.011
salivary gland morphogenesis GO:0007435 1 0.011
regulation of dna metabolic process GO:0051052 60 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
positive regulation of cell development GO:0010720 176 0.010
hemostasis GO:0007599 26 0.010
developmental process involved in reproduction GO:0003006 159 0.010
regulation of actin filament based process GO:0032970 42 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
gamete generation GO:0007276 124 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
positive regulation of cytokine production GO:0001819 42 0.010
sequestering of calcium ion GO:0051208 8 0.010
cellular macromolecule localization GO:0070727 122 0.010

Fgd5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.012