Rattus norvegicus

144 known processes

Il10

interleukin 10

(Aliases: IL10X)

Il10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.385
organic hydroxy compound metabolic process GO:1901615 115 0.326
response to lipopolysaccharide GO:0032496 191 0.296
regulation of saliva secretion GO:0046877 3 0.290
cellular response to endogenous stimulus GO:0071495 377 0.263
positive regulation of lymphocyte proliferation GO:0050671 20 0.228
response to external biotic stimulus GO:0043207 221 0.214
response to biotic stimulus GO:0009607 226 0.202
response to estrogen GO:0043627 232 0.192
response to other organism GO:0051707 220 0.178
response to heat GO:0009408 60 0.174
response to molecule of bacterial origin GO:0002237 194 0.164
multi organism reproductive process GO:0044703 262 0.162
phasic smooth muscle contraction GO:0014821 3 0.155
lymphocyte activation GO:0046649 43 0.149
Human
regulation of multicellular organismal development GO:2000026 376 0.145
multi multicellular organism process GO:0044706 138 0.145
response to estradiol GO:0032355 164 0.141
saliva secretion GO:0046541 3 0.141
lymphocyte proliferation GO:0046651 29 0.126
Human
positive regulation of multicellular organismal process GO:0051240 387 0.124
Human
response to nutrient levels GO:0031667 370 0.117
reproductive process GO:0022414 372 0.116
response to bacterium GO:0009617 200 0.111
defense response GO:0006952 194 0.109
feeding behavior GO:0007631 53 0.106
response to glucocorticoid GO:0051384 223 0.104
response to corticosteroid GO:0031960 235 0.098
metal ion transport GO:0030001 289 0.098
positive regulation of immunoglobulin production GO:0002639 4 0.095
cellular amino acid metabolic process GO:0006520 107 0.093
positive regulation of response to stimulus GO:0048584 285 0.093
Rat
catabolic process GO:0009056 351 0.092
Human
positive regulation of protein metabolic process GO:0051247 178 0.089
Rat
chemical homeostasis GO:0048878 292 0.084
positive regulation of cell activation GO:0050867 34 0.083
amine metabolic process GO:0009308 38 0.080
sodium ion transport GO:0006814 82 0.078
positive regulation of leukocyte proliferation GO:0070665 20 0.077
regulation of lymphocyte proliferation GO:0050670 26 0.077
Human
single organism reproductive process GO:0044702 297 0.075
positive regulation of immune system process GO:0002684 90 0.075
response to alkaloid GO:0043279 132 0.074
mononuclear cell proliferation GO:0032943 29 0.074
Human
response to ethanol GO:0045471 162 0.074
peristalsis GO:0030432 2 0.073
regulation of protein modification process GO:0031399 194 0.073
Rat
homeostatic process GO:0042592 331 0.071
regulation of leukocyte proliferation GO:0070663 26 0.069
Human
positive regulation of saliva secretion GO:0046878 3 0.069
regeneration GO:0031099 163 0.067
regulation of protein phosphorylation GO:0001932 183 0.065
Rat
regulation of response to external stimulus GO:0032101 106 0.064
regulation of molecular function GO:0065009 398 0.063
Human
response to temperature stimulus GO:0009266 94 0.063
organ morphogenesis GO:0009887 75 0.061
positive regulation of cell differentiation GO:0045597 217 0.060
cellular response to lipid GO:0071396 201 0.058
liver development GO:0001889 90 0.058
negative regulation of glutamate secretion GO:0014050 9 0.056
positive regulation of lymphocyte activation GO:0051251 25 0.055
regulation of ion transport GO:0043269 245 0.054
positive regulation of cell proliferation GO:0008284 249 0.054
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.053
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
Human
response to peptide hormone GO:0043434 278 0.052
negative regulation of organic acid transport GO:0032891 14 0.052
positive regulation of protein modification process GO:0031401 142 0.052
Rat
regulation of mononuclear cell proliferation GO:0032944 26 0.051
Human
regulation of cell activation GO:0050865 50 0.051
Human
regulation of anatomical structure morphogenesis GO:0022603 141 0.051
response to wounding GO:0009611 254 0.051
forebrain development GO:0030900 98 0.050
cellular amine metabolic process GO:0044106 38 0.049
organophosphate metabolic process GO:0019637 370 0.047
negative regulation of chronic inflammatory response GO:0002677 2 0.047
positive regulation of mononuclear cell proliferation GO:0032946 20 0.046
organic substance catabolic process GO:1901575 316 0.046
Human
reactive oxygen species metabolic process GO:0072593 37 0.046
leukocyte proliferation GO:0070661 29 0.046
Human
multicellular organism reproduction GO:0032504 233 0.045
regulation of protein metabolic process GO:0051246 289 0.045
carboxylic acid metabolic process GO:0019752 289 0.044
wound healing GO:0042060 122 0.044
Rat
response to radiation GO:0009314 137 0.044
response to acid chemical GO:0001101 222 0.044
cellular homeostasis GO:0019725 252 0.043
inflammatory response GO:0006954 150 0.042
jak stat cascade GO:0007259 26 0.041
Rat
regulation of phosphate metabolic process GO:0019220 349 0.040
Rat
positive regulation of developmental process GO:0051094 283 0.040
negative regulation of amino acid transport GO:0051956 13 0.040
positive regulation of cellular protein metabolic process GO:0032270 167 0.040
Rat
regulation of anion transport GO:0044070 43 0.039
cellular chemical homeostasis GO:0055082 247 0.039
nucleotide metabolic process GO:0009117 279 0.039
response to reactive oxygen species GO:0000302 120 0.039
calcium ion transmembrane transport GO:0070588 70 0.039
cellular cation homeostasis GO:0030003 180 0.039
urinary tract smooth muscle contraction GO:0014848 4 0.037
immune response GO:0006955 104 0.037
epithelial cell proliferation GO:0050673 54 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
organonitrogen compound catabolic process GO:1901565 179 0.036
positive regulation of leukocyte activation GO:0002696 30 0.035
regulation of cell differentiation GO:0045595 320 0.035
reproduction GO:0000003 245 0.034
cellular ion homeostasis GO:0006873 184 0.034
response to growth factor GO:0070848 189 0.033
regulation of immune system process GO:0002682 123 0.033
Human
cellular catabolic process GO:0044248 295 0.033
Human
cellular response to organic cyclic compound GO:0071407 202 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
regulation of epithelial cell proliferation GO:0050678 49 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
positive regulation of biosynthetic process GO:0009891 319 0.032
Human
response to nicotine GO:0035094 51 0.032
regulation of apoptotic process GO:0042981 335 0.032
phenol containing compound metabolic process GO:0018958 30 0.032
ion homeostasis GO:0050801 212 0.031
regulation of immunoglobulin production GO:0002637 4 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
regulation of cell development GO:0060284 263 0.031
protein phosphorylation GO:0006468 345 0.031
Rat
regulation of immune response GO:0050776 55 0.030
Human
regulation of protein kinase activity GO:0045859 105 0.030
immune effector process GO:0002252 53 0.030
Human
regulation of catalytic activity GO:0050790 304 0.030
positive regulation of molecular function GO:0044093 230 0.030
Human
cation transmembrane transport GO:0098655 263 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
positive regulation of cell death GO:0010942 184 0.030
Human
response to organophosphorus GO:0046683 102 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.029
Rat
peptidyl tyrosine modification GO:0018212 72 0.029
Rat
cellular response to corticosteroid stimulus GO:0071384 69 0.029
smooth muscle contraction GO:0006939 37 0.029
macromolecule localization GO:0033036 252 0.029
Human
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
Rat
blood vessel development GO:0001568 69 0.028
somatostatin receptor signaling pathway GO:0038169 4 0.028
regulation of defense response GO:0031347 68 0.028
cellular response to glucocorticoid stimulus GO:0071385 68 0.028
regulation of reactive oxygen species metabolic process GO:2000377 26 0.028
t cell proliferation GO:0042098 19 0.028
response to cytokine GO:0034097 215 0.027
Rat
regulation of cell proliferation GO:0042127 359 0.027
Human Rat
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 1 0.027
multicellular organism growth GO:0035264 1 0.027
urinary bladder smooth muscle contraction GO:0014832 4 0.026
acute inflammatory response GO:0002526 58 0.026
peptidyl amino acid modification GO:0018193 126 0.026
Rat
cellular response to alkaloid GO:0071312 25 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
positive regulation of synaptic transmission GO:0050806 62 0.025
regulation of response to wounding GO:1903034 69 0.025
positive regulation of jak stat cascade GO:0046427 19 0.025
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.025
coagulation GO:0050817 28 0.025
female pregnancy GO:0007565 122 0.025
ossification GO:0001503 70 0.025
sexual reproduction GO:0019953 148 0.025
cytokine production GO:0001816 61 0.025
negative regulation of molecular function GO:0044092 133 0.025
response to nutrient GO:0007584 248 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.024
response to extracellular stimulus GO:0009991 380 0.024
positive regulation of signal transduction GO:0009967 175 0.024
Rat
positive regulation of epithelial cell proliferation GO:0050679 32 0.024
cellular response to molecule of bacterial origin GO:0071219 56 0.024
Rat
negative regulation of innate immune response GO:0045824 4 0.024
cellular component biogenesis GO:0044085 368 0.024
positive regulation of nervous system development GO:0051962 178 0.024
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.024
intracellular signal transduction GO:0035556 314 0.024
Rat
neuropeptide signaling pathway GO:0007218 29 0.024
glutamate receptor signaling pathway GO:0007215 43 0.023
glycerolipid metabolic process GO:0046486 67 0.023
purine containing compound metabolic process GO:0072521 253 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
response to oxidative stress GO:0006979 186 0.023
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.022
angiotensin mediated drinking behavior GO:0003051 2 0.022
organ regeneration GO:0031100 101 0.022
response to inorganic substance GO:0010035 377 0.022
protein complex subunit organization GO:0071822 302 0.022
lipid transport GO:0006869 61 0.022
regulation of transporter activity GO:0032409 50 0.022
oxoacid metabolic process GO:0043436 290 0.022
response to morphine GO:0043278 27 0.022
cellular lipid metabolic process GO:0044255 208 0.021
ovulation cycle process GO:0022602 50 0.021
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
regulation of body fluid levels GO:0050878 90 0.021
lipid metabolic process GO:0006629 283 0.020
alpha amino acid catabolic process GO:1901606 20 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
Rat
positive regulation of cell development GO:0010720 176 0.020
defense response to other organism GO:0098542 17 0.020
positive regulation of immune response GO:0050778 42 0.020
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.020
respiratory system development GO:0060541 45 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of jak stat cascade GO:0046425 21 0.019
Rat
single organism catabolic process GO:0044712 283 0.019
cellular response to biotic stimulus GO:0071216 59 0.019
Rat
gamete generation GO:0007276 124 0.019
organic acid metabolic process GO:0006082 292 0.019
regulation of necroptotic process GO:0060544 2 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.018
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.018
regulation of kinase activity GO:0043549 117 0.018
heat acclimation GO:0010286 1 0.018
response to interleukin 1 GO:0070555 55 0.018
ovulation cycle GO:0042698 67 0.018
drinking behavior GO:0042756 11 0.018
amine transport GO:0015837 57 0.018
regulation of signal transduction GO:0009966 318 0.018
Rat
negative regulation of cell death GO:0060548 229 0.018
tissue remodeling GO:0048771 40 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
Human
head development GO:0060322 247 0.018
blood vessel morphogenesis GO:0048514 58 0.017
regulation of rna metabolic process GO:0051252 391 0.017
Human
negative regulation of developmental process GO:0051093 125 0.017
cell activation GO:0001775 97 0.017
Human
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
interleukin 1 mediated signaling pathway GO:0070498 2 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
cell motility GO:0048870 202 0.017
Rat
hemostasis GO:0007599 26 0.017
response to toxic substance GO:0009636 133 0.017
response to antibiotic GO:0046677 39 0.017
neurological system process GO:0050877 219 0.016
regulation of homeostatic process GO:0032844 101 0.016
steroid biosynthetic process GO:0006694 48 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
Human
eating behavior GO:0042755 21 0.016
eosinophil migration GO:0072677 3 0.016
regulation of membrane potential GO:0042391 110 0.016
regulation of nervous system development GO:0051960 264 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
body fluid secretion GO:0007589 41 0.016
aging GO:0007568 241 0.016
urogenital system development GO:0001655 78 0.016
sensory perception of pain GO:0019233 73 0.016
protein complex biogenesis GO:0070271 263 0.016
innate immune response GO:0045087 35 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
negative regulation of amine transport GO:0051953 24 0.016
regulation of transmembrane transporter activity GO:0022898 49 0.016
muscle contraction GO:0006936 88 0.015
regulation of cellular extravasation GO:0002691 2 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
regulation of phosphorylation GO:0042325 248 0.015
Rat
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
temperature homeostasis GO:0001659 17 0.015
cellular response to lipopolysaccharide GO:0071222 55 0.015
Rat
nucleoside metabolic process GO:0009116 179 0.015
metal ion homeostasis GO:0055065 186 0.015
cellular ketone metabolic process GO:0042180 51 0.015
blood coagulation GO:0007596 26 0.015
response to isoquinoline alkaloid GO:0014072 28 0.015
organophosphate catabolic process GO:0046434 148 0.015
regulation of immune response to tumor cell GO:0002837 3 0.015
single organism behavior GO:0044708 130 0.014
micturition GO:0060073 4 0.014
macromolecular complex assembly GO:0065003 273 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
Human
b cell activation involved in immune response GO:0002312 1 0.014
regulation of b cell proliferation GO:0030888 6 0.014
Human
eosinophil chemotaxis GO:0048245 3 0.014
gland development GO:0048732 155 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
necroptotic process GO:0070266 2 0.014
brain renin angiotensin system GO:0002035 3 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of leukocyte activation GO:0002694 45 0.014
Human
regulation of neuron death GO:1901214 115 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
defense response to gram positive bacterium GO:0050830 2 0.014
regulation of mast cell chemotaxis GO:0060753 1 0.014
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.014
neuron neuron synaptic transmission GO:0007270 60 0.014
positive regulation of intracellular transport GO:0032388 39 0.014
steroid metabolic process GO:0008202 73 0.014
response to purine containing compound GO:0014074 126 0.014
regulation of transferase activity GO:0051338 123 0.014
smooth muscle contraction involved in micturition GO:0060083 1 0.014
response to metal ion GO:0010038 253 0.013
alcohol metabolic process GO:0006066 77 0.013
regulation of neurogenesis GO:0050767 247 0.013
synaptic transmission GO:0007268 235 0.013
single organism biosynthetic process GO:0044711 342 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
response to xenobiotic stimulus GO:0009410 23 0.013
neuron development GO:0048666 286 0.013
ras protein signal transduction GO:0007265 29 0.013
regulation of adenylate cyclase activity GO:0045761 18 0.013
regulation of organic acid transport GO:0032890 35 0.013
negative regulation of ion transport GO:0043271 51 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of transmembrane transport GO:0034762 122 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
response to tumor cell GO:0002347 4 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
somatostatin signaling pathway GO:0038170 4 0.013
regulation of response to food GO:0032095 11 0.013
cellular biogenic amine metabolic process GO:0006576 30 0.013
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
anterior posterior pattern specification GO:0009952 1 0.013
negative regulation of synaptic transmission gabaergic GO:0032229 6 0.013
circulatory system process GO:0003013 183 0.013
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 2 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
regulation of vascular permeability GO:0043114 10 0.013
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.013
protein homooligomerization GO:0051260 91 0.013
growth GO:0040007 165 0.012
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.012
spermatogenesis GO:0007283 99 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of secretion GO:0051046 224 0.012
Human
regulation of acute inflammatory response GO:0002673 23 0.012
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.012
response to carbohydrate GO:0009743 183 0.012
operant conditioning GO:0035106 4 0.012
acute phase response GO:0006953 20 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
cellular amino acid catabolic process GO:0009063 21 0.012
cellular response to alcohol GO:0097306 87 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
brain development GO:0007420 247 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
cell killing GO:0001906 13 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
Rat
behavior GO:0007610 205 0.012
cellular response to ammonium ion GO:0071242 17 0.012
positive regulation of epithelial cell migration GO:0010634 13 0.012
positive regulation of somatostatin secretion GO:0090274 4 0.012
leukocyte activation GO:0045321 76 0.012
Human
regulation of synaptic transmission gabaergic GO:0032228 17 0.012
hormone metabolic process GO:0042445 69 0.012
neuron projection development GO:0031175 273 0.012
response to food GO:0032094 27 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
positive regulation of cell motility GO:2000147 97 0.011
phospholipid metabolic process GO:0006644 61 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
male gamete generation GO:0048232 99 0.011
regulation of programmed cell death GO:0043067 341 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
positive regulation of kinase activity GO:0033674 77 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.011
Human
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.011
synaptic transmission glutamatergic GO:0035249 33 0.011
regulation of lymphocyte activation GO:0051249 34 0.011
Human
alpha amino acid metabolic process GO:1901605 71 0.011
organic acid transport GO:0015849 116 0.011
tachykinin receptor signaling pathway GO:0007217 3 0.011
platelet aggregation GO:0070527 4 0.011
memory GO:0007613 54 0.011
cellular response to metal ion GO:0071248 55 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of ossification GO:0030278 32 0.011
acid secretion GO:0046717 48 0.011
ion transmembrane transport GO:0034220 365 0.011
regulation of immune effector process GO:0002697 32 0.011
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
cellular protein localization GO:0034613 122 0.011
cellular response to estradiol stimulus GO:0071392 16 0.011
cognition GO:0050890 92 0.011
inflammatory response to antigenic stimulus GO:0002437 18 0.011
central nervous system development GO:0007417 311 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
positive regulation of transport GO:0051050 245 0.011
Human
regulation of response to stress GO:0080134 126 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of necrotic cell death GO:0010940 4 0.011
fatty acid derivative transport GO:1901571 15 0.011
cellular response to nitrogen compound GO:1901699 210 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
glycerophospholipid metabolic process GO:0006650 47 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
cytokine biosynthetic process GO:0042089 3 0.010
regulation of interferon gamma production GO:0032649 3 0.010
gastrulation GO:0007369 2 0.010
secretion by cell GO:0032940 248 0.010
Human
sequestering of metal ion GO:0051238 9 0.010
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.010
regulation of glutamate receptor signaling pathway GO:1900449 17 0.010
regulation of sensory perception of pain GO:0051930 29 0.010
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
Rat
protein oligomerization GO:0051259 191 0.010

Il10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org