Rattus norvegicus

241 known processes

Il1a

interleukin 1 alpha

(Aliases: IL-1 alpha)

Il1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of fever generation GO:0031622 5 0.857
regulation of fever generation GO:0031620 6 0.833
response to bacterium GO:0009617 200 0.799
neutrophil migration GO:1990266 12 0.699
response to lipopolysaccharide GO:0032496 191 0.688
regulation of lymphocyte chemotaxis GO:1901623 1 0.669
response to gamma radiation GO:0010332 24 0.664
myeloid leukocyte migration GO:0097529 20 0.641
regulation of intracellular signal transduction GO:1902531 218 0.623
response to glucocorticoid GO:0051384 223 0.611
positive regulation of cellular component movement GO:0051272 102 0.602
t helper 1 cell extravasation GO:0035687 1 0.580
response to wounding GO:0009611 254 0.556
response to vitamin d GO:0033280 34 0.539
fever generation GO:0001660 9 0.503
positive regulation of leukocyte migration GO:0002687 21 0.496
positive regulation of mapk cascade GO:0043410 92 0.493
leukocyte chemotaxis GO:0030595 22 0.458
regulation of cell migration GO:0030334 128 0.447
cellular ion homeostasis GO:0006873 184 0.441
response to molecule of bacterial origin GO:0002237 194 0.430
response to other organism GO:0051707 220 0.420
t cell chemotaxis GO:0010818 2 0.406
cytokine mediated signaling pathway GO:0019221 43 0.406
regulation of neutrophil migration GO:1902622 6 0.405
positive regulation of intracellular signal transduction GO:1902533 138 0.401
temperature homeostasis GO:0001659 17 0.397
leukocyte migration GO:0050900 38 0.392
vitamin d metabolic process GO:0042359 4 0.390
positive regulation of leukocyte chemotaxis GO:0002690 10 0.379
neutrophil chemotaxis GO:0030593 11 0.371
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.365
chronic inflammatory response GO:0002544 16 0.347
granulocyte chemotaxis GO:0071621 15 0.335
acute phase response GO:0006953 20 0.332
cellular response to organic cyclic compound GO:0071407 202 0.332
positive regulation of cell motility GO:2000147 97 0.329
response to corticosteroid GO:0031960 235 0.320
regulation of response to wounding GO:1903034 69 0.320
regulation of mast cell chemotaxis GO:0060753 1 0.319
localization of cell GO:0051674 202 0.318
cell motility GO:0048870 202 0.317
response to nutrient GO:0007584 248 0.317
positive regulation of leukocyte differentiation GO:1902107 13 0.299
positive regulation of neutrophil migration GO:1902624 6 0.292
intracellular signal transduction GO:0035556 314 0.290
regulation of locomotion GO:0040012 148 0.288
response to external biotic stimulus GO:0043207 221 0.288
circulatory system process GO:0003013 183 0.287
response to peptide hormone GO:0043434 278 0.284
positive regulation of signaling GO:0023056 270 0.282
response to purine containing compound GO:0014074 126 0.275
cellular chemical homeostasis GO:0055082 247 0.274
response to ionizing radiation GO:0010212 59 0.272
cell chemotaxis GO:0060326 31 0.271
positive regulation of neurogenesis GO:0050769 165 0.262
cellular response to alcohol GO:0097306 87 0.260
behavior GO:0007610 205 0.256
regulation of cell motility GO:2000145 131 0.251
macromolecule localization GO:0033036 252 0.250
cellular response to lipid GO:0071396 201 0.245
positive regulation of signal transduction GO:0009967 175 0.240
response to hypoxia GO:0001666 231 0.239
regulation of inflammatory response GO:0050727 48 0.238
regulation of leukocyte migration GO:0002685 24 0.237
eosinophil chemotaxis GO:0048245 3 0.236
heat generation GO:0031649 11 0.234
chemical homeostasis GO:0048878 292 0.234
response to nutrient levels GO:0031667 370 0.230
regulation of leukocyte chemotaxis GO:0002688 12 0.223
cellular response to nitrogen compound GO:1901699 210 0.222
neurological system process GO:0050877 219 0.220
positive regulation of locomotion GO:0040017 102 0.218
regulation of cellular component movement GO:0051270 150 0.216
regulation of cellular component organization GO:0051128 368 0.216
response to oxidative stress GO:0006979 186 0.215
regulation of system process GO:0044057 208 0.211
cellular component assembly GO:0022607 360 0.211
wound healing GO:0042060 122 0.210
cellular response to ethanol GO:0071361 13 0.209
regulation of mapk cascade GO:0043408 116 0.206
cell migration GO:0016477 197 0.204
response to peptide GO:1901652 292 0.203
regulation of response to external stimulus GO:0032101 106 0.203
response to inorganic substance GO:0010035 377 0.202
cellular response to oxygen containing compound GO:1901701 386 0.197
blood circulation GO:0008015 183 0.196
cellular response to lipopolysaccharide GO:0071222 55 0.196
carbohydrate metabolic process GO:0005975 130 0.191
positive regulation of nervous system development GO:0051962 178 0.188
positive regulation of cell migration GO:0030335 96 0.182
cellular response to external stimulus GO:0071496 118 0.180
positive regulation of transcription factor import into nucleus GO:0042993 4 0.180
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.177
cellular homeostasis GO:0019725 252 0.176
cellular calcium ion homeostasis GO:0006874 160 0.176
signal transduction by phosphorylation GO:0023014 144 0.174
granulocyte migration GO:0097530 16 0.173
neuron death GO:0070997 127 0.173
positive regulation of developmental process GO:0051094 283 0.169
cellular response to endogenous stimulus GO:0071495 377 0.166
cellular response to molecule of bacterial origin GO:0071219 56 0.166
regulation of t cell migration GO:2000404 1 0.165
interleukin 18 production GO:0032621 1 0.162
cellular response to organonitrogen compound GO:0071417 197 0.162
sensory perception of pain GO:0019233 73 0.161
inflammatory response GO:0006954 150 0.161
response to heat GO:0009408 60 0.159
response to biotic stimulus GO:0009607 226 0.157
negative regulation of rna metabolic process GO:0051253 123 0.156
regulation of phosphorylation GO:0042325 248 0.155
regulation of neutrophil chemotaxis GO:0090022 5 0.153
response to estradiol GO:0032355 164 0.151
regulation of metal ion transport GO:0010959 118 0.149
organic substance catabolic process GO:1901575 316 0.149
divalent metal ion transport GO:0070838 132 0.148
regulation of nervous system development GO:0051960 264 0.144
cellular response to steroid hormone stimulus GO:0071383 93 0.144
response to cytokine GO:0034097 215 0.142
secretion by cell GO:0032940 248 0.141
cellular response to oxidative stress GO:0034599 76 0.141
lymphocyte chemotaxis GO:0048247 3 0.140
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.140
eosinophil migration GO:0072677 3 0.139
single organism catabolic process GO:0044712 283 0.139
regulation of molecular function GO:0065009 398 0.138
homeostatic process GO:0042592 331 0.134
intracellular transport GO:0046907 185 0.130
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.129
response to interleukin 13 GO:0035962 3 0.129
positive regulation of cell death GO:0010942 184 0.129
positive regulation of cell development GO:0010720 176 0.128
positive regulation of phosphorus metabolic process GO:0010562 262 0.128
response to ketone GO:1901654 182 0.128
protein complex subunit organization GO:0071822 302 0.128
cellular divalent inorganic cation homeostasis GO:0072503 162 0.127
lipid biosynthetic process GO:0008610 128 0.125
single organism intracellular transport GO:1902582 166 0.124
positive regulation of phosphate metabolic process GO:0045937 262 0.123
regulation of signal transduction GO:0009966 318 0.123
hormone secretion GO:0046879 115 0.122
oxoacid metabolic process GO:0043436 290 0.122
organic hydroxy compound metabolic process GO:1901615 115 0.122
positive regulation of cell proliferation GO:0008284 249 0.121
divalent inorganic cation homeostasis GO:0072507 165 0.120
cellular response to ketone GO:1901655 51 0.116
regulation of neurogenesis GO:0050767 247 0.116
cellular cation homeostasis GO:0030003 180 0.116
positive regulation of cytokine biosynthetic process GO:0042108 1 0.115
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.115
cellular response to vitamin k GO:0071307 1 0.114
regulation of protein phosphorylation GO:0001932 183 0.114
positive regulation of cell differentiation GO:0045597 217 0.112
defense response to other organism GO:0098542 17 0.111
hormone transport GO:0009914 121 0.111
apoptotic process GO:0006915 381 0.110
cellular component movement GO:0006928 248 0.109
regulation of blood circulation GO:1903522 110 0.108
t cell migration GO:0072678 2 0.105
cell projection organization GO:0030030 302 0.105
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.104
amide transport GO:0042886 105 0.103
response to mechanical stimulus GO:0009612 134 0.102
response to extracellular stimulus GO:0009991 380 0.102
regulation of phosphorus metabolic process GO:0051174 349 0.101
regulation of anatomical structure morphogenesis GO:0022603 141 0.101
response to temperature stimulus GO:0009266 94 0.101
locomotion GO:0040011 237 0.100
positive regulation of response to stimulus GO:0048584 285 0.100
positive regulation of chemotaxis GO:0050921 23 0.100
alcohol metabolic process GO:0006066 77 0.100
defense response GO:0006952 194 0.099
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.098
cellular catabolic process GO:0044248 295 0.098
positive regulation of nf kappab import into nucleus GO:0042346 2 0.096
positive regulation of protein metabolic process GO:0051247 178 0.096
regulation of hormone levels GO:0010817 187 0.094
regulation of cell proliferation GO:0042127 359 0.094
regulation of multicellular organismal development GO:2000026 376 0.094
cytokine production GO:0001816 61 0.092
regulation of map kinase activity GO:0043405 53 0.091
negative regulation of biosynthetic process GO:0009890 168 0.091
regulation of chemotaxis GO:0050920 29 0.090
response to alkaloid GO:0043279 132 0.090
positive regulation of map kinase activity GO:0043406 46 0.090
response to organophosphorus GO:0046683 102 0.089
interleukin 1 alpha production GO:0032610 1 0.089
aging GO:0007568 241 0.089
response to ethanol GO:0045471 162 0.089
positive regulation of molecular function GO:0044093 230 0.089
transcription from rna polymerase ii promoter GO:0006366 252 0.088
single organism reproductive process GO:0044702 297 0.088
vitamin biosynthetic process GO:0009110 3 0.088
sequestering of metal ion GO:0051238 9 0.087
cytokine biosynthetic process GO:0042089 3 0.086
negative regulation of gene expression GO:0010629 199 0.086
neuron differentiation GO:0030182 368 0.085
cellular lipid metabolic process GO:0044255 208 0.085
regulation of apoptotic process GO:0042981 335 0.085
positive regulation of behavior GO:0048520 38 0.085
cellular response to stress GO:0033554 269 0.085
response to acid chemical GO:0001101 222 0.084
sequestering of calcium ion GO:0051208 8 0.084
lipid catabolic process GO:0016042 46 0.084
regulation of response to stress GO:0080134 126 0.083
regulation of protein modification process GO:0031399 194 0.083
response to radiation GO:0009314 137 0.082
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.082
lipid metabolic process GO:0006629 283 0.082
negative regulation of multicellular organismal process GO:0051241 203 0.082
response to vitamin GO:0033273 131 0.082
regulation of neuron differentiation GO:0045664 208 0.081
sexual reproduction GO:0019953 148 0.081
ion homeostasis GO:0050801 212 0.081
organic acid metabolic process GO:0006082 292 0.081
positive regulation of apoptotic process GO:0043065 154 0.081
positive regulation of transport GO:0051050 245 0.080
response to fatty acid GO:0070542 65 0.080
cell cell signaling GO:0007267 335 0.080
positive regulation of cellular protein metabolic process GO:0032270 167 0.080
cellular response to biotic stimulus GO:0071216 59 0.080
positive regulation of neutrophil chemotaxis GO:0090023 5 0.079
leukocyte differentiation GO:0002521 30 0.078
positive regulation of ion transport GO:0043270 94 0.078
regulation of acute inflammatory response GO:0002673 23 0.078
cellular response to cytokine stimulus GO:0071345 127 0.078
regulation of cell development GO:0060284 263 0.077
rna metabolic process GO:0016070 406 0.077
positive regulation of gene expression GO:0010628 244 0.076
catabolic process GO:0009056 351 0.076
cellular response to alkaloid GO:0071312 25 0.076
cellular response to acid chemical GO:0071229 75 0.076
interleukin 1 biosynthetic process GO:0042222 1 0.075
negative regulation of cellular metabolic process GO:0031324 281 0.075
positive regulation of multicellular organismal process GO:0051240 387 0.075
negative regulation of cell death GO:0060548 229 0.074
positive regulation of cellular biosynthetic process GO:0031328 295 0.074
regulation of transcription dna templated GO:0006355 374 0.074
regulation of behavior GO:0050795 61 0.074
protein transport GO:0015031 132 0.073
response to high density lipoprotein particle GO:0055099 2 0.073
cellular response to tumor necrosis factor GO:0071356 46 0.072
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.072
metal ion transport GO:0030001 289 0.072
erk1 and erk2 cascade GO:0070371 48 0.071
calcium ion homeostasis GO:0055074 162 0.071
positive regulation of response to external stimulus GO:0032103 51 0.071
positive regulation of cellular component organization GO:0051130 200 0.071
regulation of cellular response to stress GO:0080135 49 0.071
response to hexose GO:0009746 144 0.070
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.070
rna biosynthetic process GO:0032774 380 0.069
positive regulation of programmed cell death GO:0043068 157 0.069
acute inflammatory response GO:0002526 58 0.069
pseudopodium assembly GO:0031269 3 0.069
regulation of erk1 and erk2 cascade GO:0070372 41 0.069
positive regulation of transferase activity GO:0051347 81 0.068
chemotaxis GO:0006935 66 0.068
regulation of nf kappab import into nucleus GO:0042345 5 0.068
regulation of protein metabolic process GO:0051246 289 0.068
regulation of interleukin 1 alpha production GO:0032650 1 0.067
response to oxygen levels GO:0070482 265 0.067
negative regulation of macromolecule metabolic process GO:0010605 260 0.067
single organism carbohydrate metabolic process GO:0044723 118 0.066
positive regulation of cell communication GO:0010647 271 0.066
macromolecular complex subunit organization GO:0043933 339 0.066
cation homeostasis GO:0055080 195 0.066
response to amino acid GO:0043200 75 0.066
single organism cellular localization GO:1902580 102 0.066
second messenger mediated signaling GO:0019932 51 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.064
secretion GO:0046903 307 0.064
calcium ion transport GO:0006816 131 0.064
regulation of protein serine threonine kinase activity GO:0071900 64 0.064
regulation of neuron death GO:1901214 115 0.063
regulation of rna biosynthetic process GO:2001141 381 0.063
positive regulation of defense response GO:0031349 37 0.063
vitamin d biosynthetic process GO:0042368 2 0.063
neuron development GO:0048666 286 0.063
regulation of leukocyte differentiation GO:1902105 20 0.063
cellular response to peptide GO:1901653 133 0.063
regulation of homeostatic process GO:0032844 101 0.063
positive regulation of neuron differentiation GO:0045666 126 0.062
negative regulation of nucleic acid templated transcription GO:1903507 117 0.062
regulation of cytokine biosynthetic process GO:0042035 3 0.062
peptide hormone secretion GO:0030072 84 0.062
regulation of cell differentiation GO:0045595 320 0.062
response to estrogen GO:0043627 232 0.062
positive regulation of granulocyte chemotaxis GO:0071624 6 0.062
negative regulation of metabolic process GO:0009892 331 0.061
positive regulation of interferon gamma production GO:0032729 2 0.061
regulation of neuron apoptotic process GO:0043523 83 0.061
metal ion homeostasis GO:0055065 186 0.061
signal release GO:0023061 145 0.061
response to carbohydrate GO:0009743 183 0.060
positive regulation of smooth muscle cell migration GO:0014911 27 0.060
response to alkyl hydroperoxide GO:0033195 1 0.060
negative regulation of cellular biosynthetic process GO:0031327 161 0.060
carboxylic acid metabolic process GO:0019752 289 0.060
protein complex assembly GO:0006461 263 0.060
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.059
negative regulation of rna biosynthetic process GO:1902679 118 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.059
protein oligomerization GO:0051259 191 0.058
endomembrane system organization GO:0010256 48 0.058
cellular response to glucocorticoid stimulus GO:0071385 68 0.058
regulation of cellular amino acid metabolic process GO:0006521 2 0.058
oxidation reduction process GO:0055114 304 0.058
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.058
regulation of programmed cell death GO:0043067 341 0.058
mast cell chemotaxis GO:0002551 4 0.057
heterotypic cell cell adhesion GO:0034113 2 0.057
cellular response to mechanical stimulus GO:0071260 48 0.056
regulation of sensory perception of pain GO:0051930 29 0.056
organic anion transport GO:0015711 132 0.055
positive regulation of kinase activity GO:0033674 77 0.055
regulation of secretion by cell GO:1903530 208 0.055
regulation of interleukin 1 biosynthetic process GO:0045360 1 0.055
positive regulation of protein kinase activity GO:0045860 73 0.055
amine metabolic process GO:0009308 38 0.055
positive regulation of interleukin 1 alpha production GO:0032730 1 0.055
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.054
positive regulation of protein modification process GO:0031401 142 0.054
positive regulation of catalytic activity GO:0043085 184 0.054
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.054
positive regulation of lymphocyte migration GO:2000403 1 0.054
regulation of stress activated mapk cascade GO:0032872 23 0.053
regulation of immunoglobulin mediated immune response GO:0002889 2 0.053
cytosolic calcium ion homeostasis GO:0051480 140 0.053
reproduction GO:0000003 245 0.053
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.053
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.052
interleukin 1 production GO:0032612 11 0.052
regulation of heat generation GO:0031650 8 0.052
regulation of phagocytosis engulfment GO:0060099 4 0.052
regulation of phosphate metabolic process GO:0019220 349 0.052
response to metal ion GO:0010038 253 0.051
fat soluble vitamin biosynthetic process GO:0042362 2 0.051
regulation of calcium ion transport GO:0051924 77 0.051
mast cell migration GO:0097531 4 0.051
programmed cell death GO:0012501 392 0.051
negative regulation of signal transduction GO:0009968 83 0.051
hindlimb morphogenesis GO:0035137 2 0.050
response to growth factor GO:0070848 189 0.050
divalent inorganic cation transport GO:0072511 134 0.050
regulation of chronic inflammatory response GO:0002676 3 0.050
regulation of vasculature development GO:1901342 44 0.050
cellular amine metabolic process GO:0044106 38 0.050
regulation of defense response GO:0031347 68 0.049
positive regulation of protein phosphorylation GO:0001934 135 0.049
cellular carbohydrate metabolic process GO:0044262 72 0.049
positive regulation of rna metabolic process GO:0051254 203 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
single organism behavior GO:0044708 130 0.048
positive regulation of cytokine production GO:0001819 42 0.048
multicellular organism reproduction GO:0032504 233 0.048
establishment of protein localization GO:0045184 141 0.047
pseudopodium organization GO:0031268 3 0.047
regulation of viral transcription GO:0046782 2 0.047
cellular amino acid metabolic process GO:0006520 107 0.047
negative regulation of developmental process GO:0051093 125 0.047
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.047
cellular response to corticosteroid stimulus GO:0071384 69 0.046
cellular response to interleukin 1 GO:0071347 37 0.046
vesicle mediated transport GO:0016192 181 0.046
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.046
regulation of cytokine secretion GO:0050707 11 0.046
inflammatory response to antigenic stimulus GO:0002437 18 0.046
taxis GO:0042330 67 0.046
nucleoside phosphate metabolic process GO:0006753 283 0.046
regulation of protein kinase activity GO:0045859 105 0.046
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.046
negative regulation of ion transport GO:0043271 51 0.046
cellular response to lipoteichoic acid GO:0071223 1 0.045
positive regulation of transcription dna templated GO:0045893 197 0.045
immune response GO:0006955 104 0.045
regulation of immune system process GO:0002682 123 0.045
regulation of i kappab kinase nf kappab signaling GO:0043122 13 0.044
monosaccharide metabolic process GO:0005996 61 0.044
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 14 0.044
regulation of transferase activity GO:0051338 123 0.044
anatomical structure morphogenesis GO:0009653 298 0.044
smooth muscle cell migration GO:0014909 36 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
response to toxic substance GO:0009636 133 0.043
protein complex biogenesis GO:0070271 263 0.043
response to glucose GO:0009749 136 0.043
cation transport GO:0006812 382 0.043
negative regulation of cell proliferation GO:0008285 119 0.043
response to ddt GO:0046680 1 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
lymphocyte migration GO:0072676 3 0.042
multicellular organismal reproductive process GO:0048609 233 0.042
toxin catabolic process GO:0009407 1 0.042
terpenoid metabolic process GO:0006721 37 0.041
positive regulation of immune system process GO:0002684 90 0.041
cellular response to estradiol stimulus GO:0071392 16 0.041
release of sequestered calcium ion into cytosol GO:0051209 25 0.041
inflammatory cell apoptotic process GO:0006925 5 0.041
monocarboxylic acid metabolic process GO:0032787 152 0.041
response to xenobiotic stimulus GO:0009410 23 0.041
regulation of kinase activity GO:0043549 117 0.041
gamete generation GO:0007276 124 0.040
calcium ion transport into cytosol GO:0060402 38 0.040
single organism organelle organization GO:1902589 180 0.040
dna metabolic process GO:0006259 96 0.040
glomerular filtration GO:0003094 10 0.040
immune effector process GO:0002252 53 0.040
purine nucleotide metabolic process GO:0006163 229 0.040
regeneration GO:0031099 163 0.040
positive regulation of neuron projection development GO:0010976 99 0.039
mapk cascade GO:0000165 140 0.039
regulation of hormone secretion GO:0046883 106 0.039
regulation of blood vessel size GO:0050880 89 0.039
single organism biosynthetic process GO:0044711 342 0.039
maintenance of location GO:0051235 17 0.039
negative regulation of cell differentiation GO:0045596 99 0.039
response to sterol GO:0036314 13 0.038
response to hyperoxia GO:0055093 45 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
anatomical structure formation involved in morphogenesis GO:0048646 83 0.038
regulation of immunoglobulin secretion GO:0051023 1 0.038
positive regulation of phagocytosis engulfment GO:0060100 4 0.038
transcription dna templated GO:0006351 377 0.038
immune system process GO:0002376 204 0.038
xenobiotic catabolic process GO:0042178 7 0.038
positive regulation of biosynthetic process GO:0009891 319 0.038
response to interleukin 15 GO:0070672 4 0.038
sensory perception GO:0007600 101 0.038
regulation of cellular catabolic process GO:0031329 101 0.037
benzene containing compound metabolic process GO:0042537 22 0.037
response to electrical stimulus GO:0051602 56 0.037
protein phosphorylation GO:0006468 345 0.037
phospholipid metabolic process GO:0006644 61 0.037
response to morphine GO:0043278 27 0.037
brain development GO:0007420 247 0.037
negative regulation of osteoblast differentiation GO:0045668 2 0.037
negative regulation of neuron death GO:1901215 69 0.036
helper t cell extravasation GO:0035684 1 0.036
cellular component biogenesis GO:0044085 368 0.036
cellular response to hydroperoxide GO:0071447 2 0.036
regulation of rna metabolic process GO:0051252 391 0.036
regulation of synaptic transmission GO:0050804 141 0.036
innate immune response GO:0045087 35 0.036
response to activity GO:0014823 73 0.035
hormone metabolic process GO:0042445 69 0.035
actin cytoskeleton organization GO:0030036 73 0.035
positive regulation of cell projection organization GO:0031346 111 0.035
regulation of myeloid cell differentiation GO:0045637 12 0.035
response to reactive oxygen species GO:0000302 120 0.035
gliogenesis GO:0042063 93 0.035
cellular metal ion homeostasis GO:0006875 172 0.035
endocytosis GO:0006897 84 0.035
regulation of tube size GO:0035150 89 0.035
positive regulation of t cell migration GO:2000406 1 0.035
nitrogen compound transport GO:0071705 229 0.034
neuron projection development GO:0031175 273 0.034
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 8 0.034
response to virus GO:0009615 17 0.034
liver development GO:0001889 90 0.034
response to indole 3 methanol GO:0071680 2 0.034
negative regulation of apoptotic process GO:0043066 181 0.034
biological adhesion GO:0022610 110 0.034
defense response to gram positive bacterium GO:0050830 2 0.034
regulation of interleukin 18 production GO:0032661 1 0.034
jnk cascade GO:0007254 28 0.034
interleukin 1 alpha biosynthetic process GO:0050719 1 0.034
insulin secretion GO:0030073 69 0.033
isoprenoid metabolic process GO:0006720 45 0.033
regulation of interleukin 8 production GO:0032677 2 0.033
regulation of catalytic activity GO:0050790 304 0.033
negative regulation of programmed cell death GO:0043069 183 0.033
regulation of anatomical structure size GO:0090066 135 0.033
organophosphate metabolic process GO:0019637 370 0.033
cell type specific apoptotic process GO:0097285 134 0.033
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.033
regulation of cell cycle GO:0051726 73 0.033
angiogenesis GO:0001525 53 0.032
cellular response to hexose stimulus GO:0071331 65 0.032
positive regulation of inflammatory response GO:0050729 24 0.032
astrocyte development GO:0014002 4 0.032
reactive nitrogen species metabolic process GO:2001057 1 0.032
growth GO:0040007 165 0.032
purine containing compound metabolic process GO:0072521 253 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 7 0.031
regulation of nucleocytoplasmic transport GO:0046822 28 0.031
positive regulation of jnk cascade GO:0046330 13 0.031
g protein coupled receptor signaling pathway GO:0007186 242 0.031
immune system development GO:0002520 41 0.031
regulation of heterotypic cell cell adhesion GO:0034114 2 0.031
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.030
positive regulation of b cell mediated immunity GO:0002714 2 0.030
learning or memory GO:0007611 90 0.030
positive regulation of vasodilation GO:0045909 29 0.030

Il1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.066
gastrointestinal system cancer DOID:3119 0 0.058
cancer DOID:162 0 0.058
organ system cancer DOID:0050686 0 0.058
stomach cancer DOID:10534 0 0.050