Rattus norvegicus

0 known processes

Lrch4

leucine-rich repeats and calponin homology (CH) domain containing 4

Lrch4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein phosphorylation GO:0006468 345 0.121
intracellular transport GO:0046907 185 0.107
ion transmembrane transport GO:0034220 365 0.080
neuron development GO:0048666 286 0.078
macromolecular complex subunit organization GO:0043933 339 0.075
single organism intracellular transport GO:1902582 166 0.074
cellular component assembly GO:0022607 360 0.071
rna metabolic process GO:0016070 406 0.070
Mouse
muscle system process GO:0003012 115 0.060
multicellular organismal signaling GO:0035637 44 0.058
neurotrophin production GO:0032898 2 0.056
grooming behavior GO:0007625 4 0.055
carboxylic acid transport GO:0046942 115 0.051
cell projection organization GO:0030030 302 0.050
anion transport GO:0006820 178 0.049
organic anion transport GO:0015711 132 0.049
cellular component biogenesis GO:0044085 368 0.048
mitotic sister chromatid separation GO:0051306 1 0.048
regulation of molecular function GO:0065009 398 0.046
regulation of cellular ketone metabolic process GO:0010565 27 0.045
heart contraction GO:0060047 57 0.045
regulation of rna metabolic process GO:0051252 391 0.045
Mouse
oxoacid metabolic process GO:0043436 290 0.045
heart morphogenesis GO:0003007 3 0.044
carboxylic acid metabolic process GO:0019752 289 0.044
positive regulation of nervous system development GO:0051962 178 0.042
multi organism reproductive process GO:0044703 262 0.042
regulation of proteasomal protein catabolic process GO:0061136 4 0.042
regulation of heart contraction GO:0008016 48 0.041
regulation of cell differentiation GO:0045595 320 0.041
multicellular organismal water homeostasis GO:0050891 4 0.037
nucleic acid templated transcription GO:0097659 379 0.035
Mouse
regulation of cellular component organization GO:0051128 368 0.034
cardiac chamber development GO:0003205 1 0.033
presynaptic membrane assembly GO:0097105 3 0.033
macromolecule localization GO:0033036 252 0.033
apoptotic process GO:0006915 381 0.033
organic acid transport GO:0015849 116 0.033
reproduction GO:0000003 245 0.032
positive regulation of cell death GO:0010942 184 0.032
organelle organization GO:0006996 266 0.031
adult locomotory behavior GO:0008344 4 0.030
cardiac conduction GO:0061337 2 0.030
protein oligomerization GO:0051259 191 0.030
response to molecule of bacterial origin GO:0002237 194 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
cellular protein localization GO:0034613 122 0.029
regulation of transcription dna templated GO:0006355 374 0.029
Mouse
single organism cellular localization GO:1902580 102 0.029
protein complex assembly GO:0006461 263 0.028
anterior posterior pattern specification GO:0009952 1 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
protein localization GO:0008104 191 0.028
cellular macromolecule localization GO:0070727 122 0.028
neuron projection morphogenesis GO:0048812 122 0.028
macromolecular complex assembly GO:0065003 273 0.028
heart process GO:0003015 57 0.027
positive regulation of gene expression GO:0010628 244 0.027
intracellular signal transduction GO:0035556 314 0.026
gamete generation GO:0007276 124 0.026
regulation of cell growth GO:0001558 85 0.026
growth GO:0040007 165 0.026
tissue development GO:0009888 252 0.026
cardiac ventricle development GO:0003231 1 0.026
cell communication involved in cardiac conduction GO:0086065 2 0.026
chromosome segregation GO:0007059 2 0.026
protein complex subunit organization GO:0071822 302 0.025
rna biosynthetic process GO:0032774 380 0.025
Mouse
positive regulation of programmed cell death GO:0043068 157 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
retinal ganglion cell axon guidance GO:0031290 1 0.025
response to bacterium GO:0009617 200 0.025
cation transport GO:0006812 382 0.025
cellular amine metabolic process GO:0044106 38 0.025
cardiovascular system development GO:0072358 134 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
chromosome separation GO:0051304 1 0.024
mesoderm development GO:0007498 2 0.024
programmed cell death GO:0012501 392 0.024
regulation of neuron differentiation GO:0045664 208 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
sexual reproduction GO:0019953 148 0.023
cell growth GO:0016049 104 0.023
organic acid metabolic process GO:0006082 292 0.023
regulation of signal transduction GO:0009966 318 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of cell development GO:0060284 263 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.022
response to camp GO:0051591 91 0.022
response to cytokine GO:0034097 215 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.021
regulation of neurogenesis GO:0050767 247 0.021
regulation of cellular component biogenesis GO:0044087 86 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
lipid localization GO:0010876 62 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
metal ion transport GO:0030001 289 0.021
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
locomotor rhythm GO:0045475 1 0.021
cation transmembrane transport GO:0098655 263 0.021
striated muscle contraction GO:0006941 44 0.021
circulatory system process GO:0003013 183 0.021
embryonic pattern specification GO:0009880 1 0.021
reproductive process GO:0022414 372 0.020
regulation of programmed cell death GO:0043067 341 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of apoptotic process GO:0042981 335 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
Mouse
neuromuscular synaptic transmission GO:0007274 2 0.019
multicellular organism reproduction GO:0032504 233 0.019
positive regulation of ion transport GO:0043270 94 0.019
transmission of nerve impulse GO:0019226 42 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
Mouse
anatomical structure morphogenesis GO:0009653 298 0.019
regulation of blood circulation GO:1903522 110 0.019
amine metabolic process GO:0009308 38 0.019
protein complex biogenesis GO:0070271 263 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
metaphase anaphase transition of cell cycle GO:0044784 1 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.018
postsynaptic density protein 95 clustering GO:0097119 2 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of mitotic sister chromatid separation GO:0010965 1 0.018
axis specification GO:0009798 4 0.018
spindle organization GO:0007051 2 0.018
regulation of respiratory gaseous exchange GO:0043576 2 0.018
regulation of striated muscle contraction GO:0006942 21 0.018
regulation of system process GO:0044057 208 0.018
regulation of homeostatic process GO:0032844 101 0.018
negative regulation of multicellular organismal metabolic process GO:0044252 4 0.018
mesoderm morphogenesis GO:0048332 1 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
cellular catabolic process GO:0044248 295 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of molecular function GO:0044093 230 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
developmental growth GO:0048589 100 0.017
regulation of sister chromatid segregation GO:0033045 1 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.016
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.016
single organism organelle organization GO:1902589 180 0.016
purine containing compound catabolic process GO:0072523 138 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.016
cardiac muscle contraction GO:0060048 27 0.016
response to peptide hormone GO:0043434 278 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
rhythmic process GO:0048511 156 0.016
regulation of cell projection organization GO:0031344 175 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
cellular response to acid chemical GO:0071229 75 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
regulation of growth GO:0040008 105 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
response to ketone GO:1901654 182 0.015
sister chromatid segregation GO:0000819 1 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
intracellular protein transport GO:0006886 79 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
neuron differentiation GO:0030182 368 0.015
synaptic transmission GO:0007268 235 0.015
regulation of ion transport GO:0043269 245 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
anion transmembrane transport GO:0098656 77 0.015
organic hydroxy compound transport GO:0015850 77 0.015
regulation of phosphorylation GO:0042325 248 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
organophosphate metabolic process GO:0019637 370 0.014
neuron projection development GO:0031175 273 0.014
heterocycle catabolic process GO:0046700 167 0.014
chromosome organization GO:0051276 36 0.014
protein transport GO:0015031 132 0.014
purine containing compound metabolic process GO:0072521 253 0.014
cardiac muscle tissue morphogenesis GO:0055008 1 0.014
response to peptide GO:1901652 292 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
catabolic process GO:0009056 351 0.014
somatic stem cell maintenance GO:0035019 2 0.014
sodium ion transport GO:0006814 82 0.014
positive regulation of developmental process GO:0051094 283 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
vesicle mediated transport GO:0016192 181 0.013
protein heterooligomerization GO:0051291 89 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of synapse structure and activity GO:0050803 21 0.013
mitotic sister chromatid segregation GO:0000070 1 0.013
circulatory system development GO:0072359 134 0.013
regulation of protein metabolic process GO:0051246 289 0.013
cellular ketone metabolic process GO:0042180 51 0.013
protein targeting GO:0006605 61 0.013
cellular response to tumor necrosis factor GO:0071356 46 0.013
lipid metabolic process GO:0006629 283 0.013
male gamete generation GO:0048232 99 0.012
female pregnancy GO:0007565 122 0.012
head development GO:0060322 247 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
lipid storage GO:0019915 1 0.012
response to purine containing compound GO:0014074 126 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
muscle structure development GO:0061061 87 0.012
single organism membrane organization GO:0044802 74 0.012
regulation of neuron death GO:1901214 115 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
proteolysis GO:0006508 175 0.012
male mating behavior GO:0060179 3 0.012
cell cycle process GO:0022402 57 0.012
regulation of mitotic sister chromatid segregation GO:0033047 1 0.012
amino acid transport GO:0006865 70 0.012
regulation of protein modification process GO:0031399 194 0.012
cell projection morphogenesis GO:0048858 123 0.012
muscle contraction GO:0006936 88 0.012
brain development GO:0007420 247 0.011
regulation of neuron projection development GO:0010975 161 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
cell cycle GO:0007049 101 0.011
maternal aggressive behavior GO:0002125 3 0.011
cytoplasmic transport GO:0016482 115 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.011
muscle cell differentiation GO:0042692 52 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
cell morphogenesis GO:0000902 142 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
regulation of synapse assembly GO:0051963 15 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
dendritic spine organization GO:0097061 12 0.011
maternal behavior GO:0042711 5 0.011
lipid transport GO:0006869 61 0.011
circadian rhythm GO:0007623 88 0.011
muscle organ morphogenesis GO:0048644 1 0.011
gap junction assembly GO:0016264 2 0.011
positive regulation of neurogenesis GO:0050769 165 0.010
regulation of neuronal synaptic plasticity GO:0048168 31 0.010
positive regulation of protein modification process GO:0031401 142 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
metal ion homeostasis GO:0055065 186 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
catenin import into nucleus GO:0035411 1 0.010
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
negative regulation of heart growth GO:0061117 3 0.010
positive regulation of cell development GO:0010720 176 0.010
cellular component morphogenesis GO:0032989 155 0.010
negative regulation of protein phosphorylation GO:0001933 44 0.010
single organism catabolic process GO:0044712 283 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
regulation of monooxygenase activity GO:0032768 8 0.010
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.010

Lrch4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.109
muscular disease DOID:0080000 0 0.109
heart disease DOID:114 0 0.109
cardiomyopathy DOID:0050700 0 0.109
disease of anatomical entity DOID:7 0 0.109
cardiovascular system disease DOID:1287 0 0.109
musculoskeletal system disease DOID:17 0 0.109
muscle tissue disease DOID:66 0 0.109
intrinsic cardiomyopathy DOID:0060036 0 0.064
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.064
nervous system disease DOID:863 0 0.024
respiratory system disease DOID:1579 0 0.016
lower respiratory tract disease DOID:0050161 0 0.016
dilated cardiomyopathy DOID:12930 0 0.015
sensory system disease DOID:0050155 0 0.011