Rattus norvegicus

0 known processes

Degs1

degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)

(Aliases: Degs)

Degs1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.130
regulation of nucleic acid templated transcription GO:1903506 380 0.100
negative regulation of metabolic process GO:0009892 331 0.097
positive regulation of phosphorus metabolic process GO:0010562 262 0.095
regulation of molecular function GO:0065009 398 0.088
cellular lipid metabolic process GO:0044255 208 0.085
reproductive process GO:0022414 372 0.085
cellular response to endogenous stimulus GO:0071495 377 0.078
positive regulation of phosphate metabolic process GO:0045937 262 0.076
multi organism reproductive process GO:0044703 262 0.073
regulation of phosphate metabolic process GO:0019220 349 0.070
negative regulation of response to stimulus GO:0048585 155 0.069
oxoacid metabolic process GO:0043436 290 0.067
negative regulation of macromolecule metabolic process GO:0010605 260 0.066
lipid metabolic process GO:0006629 283 0.065
negative regulation of signaling GO:0023057 157 0.064
regulation of signal transduction GO:0009966 318 0.063
positive regulation of phosphorylation GO:0042327 177 0.061
regulation of catalytic activity GO:0050790 304 0.061
regulation of phosphorylation GO:0042325 248 0.060
regulation of apoptotic process GO:0042981 335 0.058
apoptotic process GO:0006915 381 0.058
response to extracellular stimulus GO:0009991 380 0.056
regulation of cellular component organization GO:0051128 368 0.056
negative regulation of signal transduction GO:0009968 83 0.055
regulation of protein phosphorylation GO:0001932 183 0.054
tissue development GO:0009888 252 0.054
positive regulation of molecular function GO:0044093 230 0.051
intracellular signal transduction GO:0035556 314 0.051
protein localization GO:0008104 191 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.050
signal transduction by phosphorylation GO:0023014 144 0.050
amine metabolic process GO:0009308 38 0.049
response to estrogen GO:0043627 232 0.047
negative regulation of cell communication GO:0010648 158 0.047
regulation of transcription dna templated GO:0006355 374 0.043
regulation of programmed cell death GO:0043067 341 0.043
negative regulation of cellular metabolic process GO:0031324 281 0.043
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.043
multicellular organism reproduction GO:0032504 233 0.043
regulation of rna metabolic process GO:0051252 391 0.043
organic acid metabolic process GO:0006082 292 0.042
defense response GO:0006952 194 0.042
response to nutrient levels GO:0031667 370 0.042
multicellular organismal reproductive process GO:0048609 233 0.040
cellular response to oxygen containing compound GO:1901701 386 0.039
regulation of protein metabolic process GO:0051246 289 0.039
positive regulation of cell communication GO:0010647 271 0.037
cellular response to hormone stimulus GO:0032870 247 0.037
single organism reproductive process GO:0044702 297 0.037
single organism biosynthetic process GO:0044711 342 0.036
cellular component biogenesis GO:0044085 368 0.036
neuron development GO:0048666 286 0.036
programmed cell death GO:0012501 392 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
positive regulation of signal transduction GO:0009967 175 0.034
protein complex assembly GO:0006461 263 0.033
neuron differentiation GO:0030182 368 0.033
bmp signaling pathway GO:0030509 4 0.033
single organism catabolic process GO:0044712 283 0.033
cell projection organization GO:0030030 302 0.032
inflammatory response GO:0006954 150 0.032
regulation of neuron differentiation GO:0045664 208 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
reproduction GO:0000003 245 0.031
regulation of cell development GO:0060284 263 0.031
response to nutrient GO:0007584 248 0.031
protein oligomerization GO:0051259 191 0.031
response to acid chemical GO:0001101 222 0.031
neuron projection development GO:0031175 273 0.031
regulation of rna biosynthetic process GO:2001141 381 0.030
nucleic acid templated transcription GO:0097659 379 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
transmembrane transport GO:0055085 412 0.029
central nervous system development GO:0007417 311 0.029
regulation of mapk cascade GO:0043408 116 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
protein phosphorylation GO:0006468 345 0.028
cellular amine metabolic process GO:0044106 38 0.028
regulation of cellular localization GO:0060341 263 0.028
negative regulation of phosphate metabolic process GO:0045936 80 0.028
sexual reproduction GO:0019953 148 0.028
developmental process involved in reproduction GO:0003006 159 0.027
cellular component assembly GO:0022607 360 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
response to estradiol GO:0032355 164 0.027
aging GO:0007568 241 0.027
rna metabolic process GO:0016070 406 0.027
enzyme linked receptor protein signaling pathway GO:0007167 116 0.026
lipid biosynthetic process GO:0008610 128 0.026
cation transport GO:0006812 382 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
anatomical structure morphogenesis GO:0009653 298 0.025
regulation of protein modification process GO:0031399 194 0.025
positive regulation of developmental process GO:0051094 283 0.025
response to peptide GO:1901652 292 0.025
cellular response to nitrogen compound GO:1901699 210 0.024
transcription dna templated GO:0006351 377 0.024
protein complex biogenesis GO:0070271 263 0.024
rna biosynthetic process GO:0032774 380 0.024
negative regulation of protein phosphorylation GO:0001933 44 0.024
protein complex subunit organization GO:0071822 302 0.024
regulation of cell projection organization GO:0031344 175 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
response to hypoxia GO:0001666 231 0.024
response to oxygen levels GO:0070482 265 0.024
regulation of growth GO:0040008 105 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
macromolecular complex assembly GO:0065003 273 0.024
cellular response to peptide GO:1901653 133 0.024
locomotion GO:0040011 237 0.024
positive regulation of protein modification process GO:0031401 142 0.023
positive regulation of mapk cascade GO:0043410 92 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
cell migration GO:0016477 197 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
positive regulation of cell death GO:0010942 184 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.023
response to peptide hormone GO:0043434 278 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
cellular response to stress GO:0033554 269 0.022
female pregnancy GO:0007565 122 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
positive regulation of nervous system development GO:0051962 178 0.022
regulation of bmp signaling pathway GO:0030510 2 0.022
negative regulation of molecular function GO:0044092 133 0.022
regulation of cell differentiation GO:0045595 320 0.022
positive regulation of cell development GO:0010720 176 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.021
response to decreased oxygen levels GO:0036293 237 0.021
regulation of nervous system development GO:0051960 264 0.021
negative regulation of cell death GO:0060548 229 0.021
regulation of neuron projection development GO:0010975 161 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
purine containing compound metabolic process GO:0072521 253 0.021
multi multicellular organism process GO:0044706 138 0.021
regulation of neurogenesis GO:0050767 247 0.020
gland development GO:0048732 155 0.020
macromolecule localization GO:0033036 252 0.020
cellular response to lipid GO:0071396 201 0.020
cellular catabolic process GO:0044248 295 0.020
cardiovascular system development GO:0072358 134 0.020
organ morphogenesis GO:0009887 75 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
regulation of hydrolase activity GO:0051336 143 0.019
response to growth factor GO:0070848 189 0.019
cellular ketone metabolic process GO:0042180 51 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
mapk cascade GO:0000165 140 0.019
aromatic compound catabolic process GO:0019439 168 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
response to hexose GO:0009746 144 0.018
response to inorganic substance GO:0010035 377 0.018
positive regulation of signaling GO:0023056 270 0.018
cell motility GO:0048870 202 0.018
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
response to carbohydrate GO:0009743 183 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
secretion GO:0046903 307 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
dendrite development GO:0016358 72 0.017
catabolic process GO:0009056 351 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
response to glucose GO:0009749 136 0.017
carbohydrate metabolic process GO:0005975 130 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
negative regulation of gene expression GO:0010629 199 0.017
response to metal ion GO:0010038 253 0.017
response to glucocorticoid GO:0051384 223 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
regulation of cell growth GO:0001558 85 0.016
response to mechanical stimulus GO:0009612 134 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.016
ion transmembrane transport GO:0034220 365 0.016
secretion by cell GO:0032940 248 0.016
cellular protein localization GO:0034613 122 0.016
localization of cell GO:0051674 202 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
cellular macromolecule localization GO:0070727 122 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.016
response to bacterium GO:0009617 200 0.016
epithelium development GO:0060429 96 0.016
negative regulation of transport GO:0051051 136 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
establishment of protein localization GO:0045184 141 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
cell growth GO:0016049 104 0.014
anion transport GO:0006820 178 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
response to temperature stimulus GO:0009266 94 0.014
small molecule biosynthetic process GO:0044283 124 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
organic anion transport GO:0015711 132 0.014
establishment of tissue polarity GO:0007164 2 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
carboxylic acid transport GO:0046942 115 0.014
cellular homeostasis GO:0019725 252 0.014
growth GO:0040007 165 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
chromosome segregation GO:0007059 2 0.014
cellular response to organonitrogen compound GO:0071417 197 0.013
response to monosaccharide GO:0034284 159 0.013
response to other organism GO:0051707 220 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
regulation of response to stress GO:0080134 126 0.013
regulation of protein transport GO:0051223 68 0.013
positive regulation of gene expression GO:0010628 244 0.013
regulation of establishment of planar polarity GO:0090175 2 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
hepaticobiliary system development GO:0061008 90 0.013
organophosphate metabolic process GO:0019637 370 0.013
heterocycle catabolic process GO:0046700 167 0.013
negative regulation of phosphorylation GO:0042326 57 0.013
regulation of cell proliferation GO:0042127 359 0.013
cofactor metabolic process GO:0051186 95 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
proteolysis GO:0006508 175 0.013
cellular component movement GO:0006928 248 0.012
negative regulation of developmental process GO:0051093 125 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
cell type specific apoptotic process GO:0097285 134 0.012
organophosphate catabolic process GO:0046434 148 0.012
response to corticosteroid GO:0031960 235 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
peptidyl amino acid modification GO:0018193 126 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
gamete generation GO:0007276 124 0.012
regulation of dendrite development GO:0050773 59 0.012
biological adhesion GO:0022610 110 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of protein kinase activity GO:0045859 105 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
metal ion transport GO:0030001 289 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
negative regulation of protein modification process GO:0031400 52 0.012
muscle structure development GO:0061061 87 0.012
organic substance catabolic process GO:1901575 316 0.012
brain development GO:0007420 247 0.011
endocytosis GO:0006897 84 0.011
cell adhesion GO:0007155 110 0.011
purine containing compound catabolic process GO:0072523 138 0.011
ras protein signal transduction GO:0007265 29 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
organic acid transport GO:0015849 116 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
salivary gland development GO:0007431 3 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of dna metabolic process GO:0051052 60 0.011
male gamete generation GO:0048232 99 0.011
response to toxic substance GO:0009636 133 0.011
response to retinoic acid GO:0032526 63 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
regeneration GO:0031099 163 0.011
cell activation GO:0001775 97 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
response to wounding GO:0009611 254 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
ion homeostasis GO:0050801 212 0.011
axis specification GO:0009798 4 0.011
behavior GO:0007610 205 0.011
protein transport GO:0015031 132 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
cellular component morphogenesis GO:0032989 155 0.010
spermatogenesis GO:0007283 99 0.010
circulatory system development GO:0072359 134 0.010
regulation of anatomical structure size GO:0090066 135 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
regulation of cell cycle GO:0051726 73 0.010
regulation of kinase activity GO:0043549 117 0.010
nucleotide metabolic process GO:0009117 279 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
nucleoside metabolic process GO:0009116 179 0.010
response to ethanol GO:0045471 162 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
leukocyte cell cell adhesion GO:0007159 4 0.010
response to biotic stimulus GO:0009607 226 0.010
regulation of cellular response to stress GO:0080135 49 0.010

Degs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.014
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011