Rattus norvegicus

0 known processes

Serpinb1a

serine (or cysteine) proteinase inhibitor, clade B, member 1a

(Aliases: MGC112650)

Serpinb1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to stress GO:0033554 269 0.247
macromolecular complex subunit organization GO:0043933 339 0.210
immune system process GO:0002376 204 0.201
cellular response to oxygen containing compound GO:1901701 386 0.167
response to wounding GO:0009611 254 0.164
Rat
response to inorganic substance GO:0010035 377 0.158
granulocyte chemotaxis GO:0071621 15 0.152
lipid metabolic process GO:0006629 283 0.144
carboxylic acid metabolic process GO:0019752 289 0.120
response to bacterium GO:0009617 200 0.117
response to metal ion GO:0010038 253 0.112
locomotion GO:0040011 237 0.103
localization of cell GO:0051674 202 0.100
cell activation GO:0001775 97 0.100
single organism biosynthetic process GO:0044711 342 0.095
Rat
cellular component assembly GO:0022607 360 0.090
cell projection organization GO:0030030 302 0.086
neutrophil chemotaxis GO:0030593 11 0.085
wound healing GO:0042060 122 0.085
Rat
catabolic process GO:0009056 351 0.080
Mouse
cellular amino acid metabolic process GO:0006520 107 0.078
anatomical structure morphogenesis GO:0009653 298 0.076
response to molecule of bacterial origin GO:0002237 194 0.074
cellular lipid metabolic process GO:0044255 208 0.073
positive regulation of multicellular organismal process GO:0051240 387 0.072
Rat
regulation of mononuclear cell proliferation GO:0032944 26 0.071
organic acid metabolic process GO:0006082 292 0.071
regulation of apoptotic process GO:0042981 335 0.068
response to cytokine GO:0034097 215 0.067
circulatory system process GO:0003013 183 0.066
cellular response to endogenous stimulus GO:0071495 377 0.066
response to corticosteroid GO:0031960 235 0.065
programmed cell death GO:0012501 392 0.064
regulation of signal transduction GO:0009966 318 0.063
neuron differentiation GO:0030182 368 0.062
oxoacid metabolic process GO:0043436 290 0.062
regulation of cellular component movement GO:0051270 150 0.061
response to lipopolysaccharide GO:0032496 191 0.061
response to oxidative stress GO:0006979 186 0.060
negative regulation of cell death GO:0060548 229 0.059
protein homooligomerization GO:0051260 91 0.059
defense response GO:0006952 194 0.058
transmembrane transport GO:0055085 412 0.057
cellular ketone metabolic process GO:0042180 51 0.057
blood vessel development GO:0001568 69 0.057
Rat
icosanoid biosynthetic process GO:0046456 18 0.057
protein complex biogenesis GO:0070271 263 0.057
cellular component biogenesis GO:0044085 368 0.056
leukotriene biosynthetic process GO:0019370 3 0.056
single organism catabolic process GO:0044712 283 0.055
cellular catabolic process GO:0044248 295 0.054
protein oligomerization GO:0051259 191 0.053
regulation of cell development GO:0060284 263 0.052
regulation of cell differentiation GO:0045595 320 0.052
protein complex assembly GO:0006461 263 0.051
circulatory system development GO:0072359 134 0.051
Rat
inflammatory response GO:0006954 150 0.050
antigen processing and presentation of peptide antigen GO:0048002 2 0.050
cation transport GO:0006812 382 0.050
response to ketone GO:1901654 182 0.050
fatty acid derivative metabolic process GO:1901568 38 0.049
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 1 0.047
response to ionizing radiation GO:0010212 59 0.047
response to nutrient GO:0007584 248 0.047
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.046
response to peptide GO:1901652 292 0.046
peptide metabolic process GO:0006518 32 0.046
protein complex subunit organization GO:0071822 302 0.045
secretion GO:0046903 307 0.045
homeostatic process GO:0042592 331 0.045
cellular component movement GO:0006928 248 0.044
macromolecular complex assembly GO:0065003 273 0.044
lipid biosynthetic process GO:0008610 128 0.044
apoptotic process GO:0006915 381 0.043
regulation of response to wounding GO:1903034 69 0.043
positive regulation of cell differentiation GO:0045597 217 0.042
organic acid biosynthetic process GO:0016053 83 0.042
cell motility GO:0048870 202 0.042
regulation of lipid biosynthetic process GO:0046890 38 0.042
response to transition metal nanoparticle GO:1990267 122 0.041
cellular response to lipid GO:0071396 201 0.041
myeloid leukocyte mediated immunity GO:0002444 12 0.040
central nervous system development GO:0007417 311 0.040
cellular response to oxidative stress GO:0034599 76 0.040
positive regulation of catalytic activity GO:0043085 184 0.040
regulation of protein metabolic process GO:0051246 289 0.040
Mouse Rat
icosanoid metabolic process GO:0006690 38 0.039
cellular response to organic cyclic compound GO:0071407 202 0.039
regulation of leukocyte activation GO:0002694 45 0.039
organic substance catabolic process GO:1901575 316 0.039
Mouse
signal transduction by phosphorylation GO:0023014 144 0.038
organonitrogen compound catabolic process GO:1901565 179 0.038
regulation of cell motility GO:2000145 131 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
regeneration GO:0031099 163 0.037
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
cell cell signaling GO:0007267 335 0.037
regulation of catalytic activity GO:0050790 304 0.037
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
positive regulation of cellular protein metabolic process GO:0032270 167 0.036
neuron projection development GO:0031175 273 0.036
positive regulation of phosphorylation GO:0042327 177 0.036
unsaturated fatty acid biosynthetic process GO:0006636 21 0.035
amine metabolic process GO:0009308 38 0.035
neutrophil migration GO:1990266 12 0.035
epithelium development GO:0060429 96 0.035
response to external biotic stimulus GO:0043207 221 0.035
fatty acid biosynthetic process GO:0006633 33 0.035
regulation of cell activation GO:0050865 50 0.035
cellular amide metabolic process GO:0043603 44 0.034
pseudopodium organization GO:0031268 3 0.034
regulation of leukocyte proliferation GO:0070663 26 0.033
positive regulation of cell death GO:0010942 184 0.033
hemopoiesis GO:0030097 34 0.033
response to radiation GO:0009314 137 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
Rat
cellular response to cytokine stimulus GO:0071345 127 0.032
neuron development GO:0048666 286 0.032
positive regulation of cell development GO:0010720 176 0.032
blood circulation GO:0008015 183 0.032
response to estrogen GO:0043627 232 0.031
positive regulation of molecular function GO:0044093 230 0.031
positive regulation of locomotion GO:0040017 102 0.031
cellular response to hydroperoxide GO:0071447 2 0.031
metal ion transport GO:0030001 289 0.031
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.030
negative regulation of metabolic process GO:0009892 331 0.030
Rat
t helper 1 cell extravasation GO:0035687 1 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
monocarboxylic acid biosynthetic process GO:0072330 48 0.030
unsaturated fatty acid metabolic process GO:0033559 39 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
head development GO:0060322 247 0.029
monosaccharide metabolic process GO:0005996 61 0.029
regulation of programmed cell death GO:0043067 341 0.029
response to interleukin 1 GO:0070555 55 0.029
mononuclear cell proliferation GO:0032943 29 0.029
organophosphate metabolic process GO:0019637 370 0.028
regulation of protein modification process GO:0031399 194 0.028
positive regulation of signal transduction GO:0009967 175 0.028
response to peptidoglycan GO:0032494 1 0.028
response to nutrient levels GO:0031667 370 0.028
response to molecule of fungal origin GO:0002238 3 0.028
protein processing GO:0016485 68 0.028
Rat
cognition GO:0050890 92 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
Rat
multicellular organismal reproductive process GO:0048609 233 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
reproductive process GO:0022414 372 0.027
monocarboxylic acid metabolic process GO:0032787 152 0.026
response to reactive oxygen species GO:0000302 120 0.026
neurological system process GO:0050877 219 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
regulation of lymphocyte proliferation GO:0050670 26 0.026
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.026
protein transport GO:0015031 132 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
Rat
regulation of hormone levels GO:0010817 187 0.025
intracellular signal transduction GO:0035556 314 0.025
positive regulation of response to stimulus GO:0048584 285 0.024
cellular homeostasis GO:0019725 252 0.024
positive regulation of developmental process GO:0051094 283 0.024
Rat
positive regulation of mapk cascade GO:0043410 92 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
defense response to gram positive bacterium GO:0050830 2 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
ribonucleoside monophosphate metabolic process GO:0009161 88 0.023
regulation of secretion GO:0051046 224 0.023
tissue development GO:0009888 252 0.023
Rat
regulation of cell proliferation GO:0042127 359 0.023
Rat
angiogenesis GO:0001525 53 0.023
cell matrix adhesion GO:0007160 19 0.023
axon development GO:0061564 96 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
response to glucocorticoid GO:0051384 223 0.023
antigen processing and presentation of exogenous antigen GO:0019884 1 0.023
positive regulation of immunoglobulin production GO:0002639 4 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
fatty acid metabolic process GO:0006631 99 0.022
membrane organization GO:0061024 94 0.022
proteolysis GO:0006508 175 0.022
Rat
small molecule biosynthetic process GO:0044283 124 0.022
response to zinc ion GO:0010043 39 0.021
organelle organization GO:0006996 266 0.021
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
brain development GO:0007420 247 0.021
regulation of response to stress GO:0080134 126 0.021
cell migration GO:0016477 197 0.021
anion transport GO:0006820 178 0.021
response to biotic stimulus GO:0009607 226 0.021
response to hexose GO:0009746 144 0.021
regulation of homotypic cell cell adhesion GO:0034110 4 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
positive regulation of cell communication GO:0010647 271 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
ion homeostasis GO:0050801 212 0.021
organic cyclic compound catabolic process GO:1901361 175 0.020
hexose metabolic process GO:0019318 58 0.020
single organismal cell cell adhesion GO:0016337 42 0.020
regulation of mapk cascade GO:0043408 116 0.020
divalent inorganic cation transport GO:0072511 134 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
Rat
regulation of cytokine production GO:0001817 56 0.020
Rat
cellular amine metabolic process GO:0044106 38 0.020
vasculature development GO:0001944 70 0.020
Rat
fatty acid derivative biosynthetic process GO:1901570 18 0.020
cellular response to biotic stimulus GO:0071216 59 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
single organism organelle organization GO:1902589 180 0.020
single organism membrane organization GO:0044802 74 0.020
response to mechanical stimulus GO:0009612 134 0.020
nucleotide metabolic process GO:0009117 279 0.020
leukocyte cell cell adhesion GO:0007159 4 0.020
positive regulation of transport GO:0051050 245 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.019
intracellular protein transport GO:0006886 79 0.019
exocytosis GO:0006887 60 0.019
mast cell migration GO:0097531 4 0.019
regulation of anatomical structure size GO:0090066 135 0.019
positive regulation of protein modification process GO:0031401 142 0.019
response to other organism GO:0051707 220 0.019
regulation of ion transport GO:0043269 245 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
negative regulation of cell communication GO:0010648 158 0.019
telencephalon development GO:0021537 62 0.019
response to estradiol GO:0032355 164 0.019
single organism cell adhesion GO:0098602 46 0.019
cellular response to corticosteroid stimulus GO:0071384 69 0.019
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 1 0.019
ion transmembrane transport GO:0034220 365 0.018
regulation of protein kinase activity GO:0045859 105 0.018
positive regulation of cell migration GO:0030335 96 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
leukocyte proliferation GO:0070661 29 0.018
regulation of hydrolase activity GO:0051336 143 0.018
Rat
cellular response to reactive oxygen species GO:0034614 55 0.018
regulation of immune system process GO:0002682 123 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
biological adhesion GO:0022610 110 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
regulation of cellular component organization GO:0051128 368 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
mapk cascade GO:0000165 140 0.017
hematopoietic or lymphoid organ development GO:0048534 36 0.017
positive regulation of cell motility GO:2000147 97 0.017
cell part morphogenesis GO:0032990 123 0.017
cell adhesion GO:0007155 110 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
cellular response to molecule of bacterial origin GO:0071219 56 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
regulation of vasculature development GO:1901342 44 0.017
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.017
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.017
blood vessel morphogenesis GO:0048514 58 0.017
forebrain development GO:0030900 98 0.017
organophosphate catabolic process GO:0046434 148 0.017
regulation of neuron projection development GO:0010975 161 0.017
regulation of molecular function GO:0065009 398 0.017
Rat
behavior GO:0007610 205 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
regulation of cell migration GO:0030334 128 0.016
positive regulation of signaling GO:0023056 270 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
regulation of membrane potential GO:0042391 110 0.016
response to growth factor GO:0070848 189 0.016
regulation of homeostatic process GO:0032844 101 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
negative regulation of signaling GO:0023057 157 0.016
cellular metal ion homeostasis GO:0006875 172 0.015
regulation of neuron death GO:1901214 115 0.015
heterotypic cell cell adhesion GO:0034113 2 0.015
regulation of growth GO:0040008 105 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
response to interleukin 13 GO:0035962 3 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
chemosensory behavior GO:0007635 2 0.015
gland development GO:0048732 155 0.015
lymphocyte activation GO:0046649 43 0.015
synaptic transmission GO:0007268 235 0.015
acute inflammatory response GO:0002526 58 0.015
regulation of transferase activity GO:0051338 123 0.015
neuron death GO:0070997 127 0.015
granulocyte migration GO:0097530 16 0.015
positive regulation of dna metabolic process GO:0051054 39 0.015
single organism behavior GO:0044708 130 0.015
antigen processing and presentation GO:0019882 2 0.014
carbohydrate metabolic process GO:0005975 130 0.014
purine containing compound metabolic process GO:0072521 253 0.014
regulation of lymphocyte activation GO:0051249 34 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
endomembrane system organization GO:0010256 48 0.014
secondary metabolic process GO:0019748 15 0.014
response to purine containing compound GO:0014074 126 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
prostate gland development GO:0030850 9 0.014
positive regulation of angiogenesis GO:0045766 28 0.014
cell substrate adhesion GO:0031589 29 0.014
epithelial cell differentiation GO:0030855 71 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
intracellular transport GO:0046907 185 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
cellular ion homeostasis GO:0006873 184 0.013
lymphocyte proliferation GO:0046651 29 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
cell projection morphogenesis GO:0048858 123 0.013
response to ethanol GO:0045471 162 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
protein targeting GO:0006605 61 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
signal release GO:0023061 145 0.013
prostaglandin metabolic process GO:0006693 12 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
reproductive system development GO:0061458 128 0.013
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 1 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
organ regeneration GO:0031100 101 0.013
negative regulation of nervous system development GO:0051961 79 0.013
response to axon injury GO:0048678 59 0.013
regulation of kinase activity GO:0043549 117 0.013
autophagic cell death GO:0048102 4 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
positive regulation of leukocyte migration GO:0002687 21 0.013
single organism intracellular transport GO:1902582 166 0.013
response to hydrogen peroxide GO:0042542 89 0.013
olfactory behavior GO:0042048 2 0.013
cellular component morphogenesis GO:0032989 155 0.013
axis specification GO:0009798 4 0.013
reproduction GO:0000003 245 0.013
regulation of stress activated mapk cascade GO:0032872 23 0.013
tube development GO:0035295 89 0.013
single organism cellular localization GO:1902580 102 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
jnk cascade GO:0007254 28 0.012
cellular response to ketone GO:1901655 51 0.012
purine containing compound catabolic process GO:0072523 138 0.012
regulation of blood pressure GO:0008217 83 0.012
cytokine biosynthetic process GO:0042089 3 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
positive regulation of interleukin 1 alpha production GO:0032730 1 0.012
cellular response to external stimulus GO:0071496 118 0.012
hormone metabolic process GO:0042445 69 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
single organism reproductive process GO:0044702 297 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
Rat
lung development GO:0030324 43 0.012
cell activation involved in immune response GO:0002263 16 0.012
b cell mediated immunity GO:0019724 4 0.012
transcription dna templated GO:0006351 377 0.012
leukocyte activation GO:0045321 76 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
positive regulation of nervous system development GO:0051962 178 0.012
ncrna processing GO:0034470 3 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
dna geometric change GO:0032392 4 0.012
regulation of cellular response to stress GO:0080135 49 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
response to tumor necrosis factor GO:0034612 56 0.011
response to decreased oxygen levels GO:0036293 237 0.011
cell type specific apoptotic process GO:0097285 134 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
stress activated protein kinase signaling cascade GO:0031098 37 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
response to acid chemical GO:0001101 222 0.011
leukocyte aggregation GO:0070486 1 0.011
protein maturation GO:0051604 68 0.011
Rat
reproductive structure development GO:0048608 128 0.011
chronic inflammatory response GO:0002544 16 0.011
chemical homeostasis GO:0048878 292 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
chemotaxis GO:0006935 66 0.011
regulation of response to external stimulus GO:0032101 106 0.011
cardiovascular system development GO:0072358 134 0.011
Rat
response to vitamin GO:0033273 131 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
response to oxygen levels GO:0070482 265 0.011
regulation of locomotion GO:0040012 148 0.011
dephosphorylation GO:0016311 98 0.011
eosinophil migration GO:0072677 3 0.011
positive regulation of homotypic cell cell adhesion GO:0034112 2 0.011
apoptotic signaling pathway GO:0097190 27 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
cellular response to acid chemical GO:0071229 75 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
regulation of t cell migration GO:2000404 1 0.011
developmental process involved in reproduction GO:0003006 159 0.011
protein autophosphorylation GO:0046777 66 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
prostaglandin biosynthetic process GO:0001516 12 0.010
salivary gland development GO:0007431 3 0.010
leukocyte differentiation GO:0002521 30 0.010
regulation of lymphocyte chemotaxis GO:1901623 1 0.010
cytoskeleton organization GO:0007010 111 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
cell morphogenesis GO:0000902 142 0.010
limbic system development GO:0021761 38 0.010
response to monosaccharide GO:0034284 159 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
Rat
regulation of lymphocyte migration GO:2000401 1 0.010
regulation of system process GO:0044057 208 0.010
retinal metabolic process GO:0042574 3 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
cellular response to alcohol GO:0097306 87 0.010
neuron projection morphogenesis GO:0048812 122 0.010
urogenital system development GO:0001655 78 0.010
Rat
divalent metal ion transport GO:0070838 132 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010

Serpinb1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org