Rattus norvegicus

0 known processes

Fgf4

fibroblast growth factor 4

(Aliases: Hst1,Hst)

Fgf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.182
transcription from rna polymerase ii promoter GO:0006366 252 0.156
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.151
transmembrane transport GO:0055085 412 0.145
rna biosynthetic process GO:0032774 380 0.144
positive regulation of signaling GO:0023056 270 0.121
nucleic acid templated transcription GO:0097659 379 0.121
regulation of secretion GO:0051046 224 0.108
organophosphate metabolic process GO:0019637 370 0.107
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.107
positive regulation of cellular biosynthetic process GO:0031328 295 0.101
transcription dna templated GO:0006351 377 0.101
positive regulation of biosynthetic process GO:0009891 319 0.096
ion transmembrane transport GO:0034220 365 0.094
rna metabolic process GO:0016070 406 0.093
regulation of transcription dna templated GO:0006355 374 0.090
carbohydrate derivative metabolic process GO:1901135 346 0.084
positive regulation of gene expression GO:0010628 244 0.080
ribose phosphate biosynthetic process GO:0046390 87 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.076
cellular response to nitrogen compound GO:1901699 210 0.072
response to cytokine GO:0034097 215 0.072
positive regulation of rna metabolic process GO:0051254 203 0.071
purine ribonucleotide metabolic process GO:0009150 227 0.070
nucleoside phosphate metabolic process GO:0006753 283 0.069
regulation of nucleic acid templated transcription GO:1903506 380 0.066
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.065
reproductive system development GO:0061458 128 0.064
cellular metal ion homeostasis GO:0006875 172 0.063
cellular amine metabolic process GO:0044106 38 0.063
regulation of multicellular organismal development GO:2000026 376 0.062
secretion GO:0046903 307 0.061
regulation of transmembrane transport GO:0034762 122 0.059
cell cell signaling GO:0007267 335 0.058
macromolecular complex subunit organization GO:0043933 339 0.057
positive regulation of response to stimulus GO:0048584 285 0.056
reproductive process GO:0022414 372 0.055
oxoacid metabolic process GO:0043436 290 0.054
cell projection organization GO:0030030 302 0.053
regulation of rna metabolic process GO:0051252 391 0.052
neuron differentiation GO:0030182 368 0.051
single organism catabolic process GO:0044712 283 0.051
regulation of secretion by cell GO:1903530 208 0.050
response to alkaloid GO:0043279 132 0.049
ribonucleotide metabolic process GO:0009259 231 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
secretion by cell GO:0032940 248 0.045
purine nucleotide metabolic process GO:0006163 229 0.044
positive regulation of nucleic acid templated transcription GO:1903508 197 0.044
organic acid metabolic process GO:0006082 292 0.044
response to extracellular stimulus GO:0009991 380 0.044
positive regulation of rna biosynthetic process GO:1902680 197 0.042
protein complex subunit organization GO:0071822 302 0.042
regeneration GO:0031099 163 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
purine containing compound metabolic process GO:0072521 253 0.041
cellular chemical homeostasis GO:0055082 247 0.041
organonitrogen compound catabolic process GO:1901565 179 0.041
negative regulation of signaling GO:0023057 157 0.041
ribose phosphate metabolic process GO:0019693 235 0.041
neuron development GO:0048666 286 0.040
organonitrogen compound biosynthetic process GO:1901566 167 0.040
cellular response to organonitrogen compound GO:0071417 197 0.040
amine metabolic process GO:0009308 38 0.040
regulation of signal transduction GO:0009966 318 0.039
cellular component assembly GO:0022607 360 0.039
regulation of cell development GO:0060284 263 0.038
positive regulation of transcription dna templated GO:0045893 197 0.036
positive regulation of neurogenesis GO:0050769 165 0.036
cellular response to hormone stimulus GO:0032870 247 0.036
response to tumor necrosis factor GO:0034612 56 0.036
single organism carbohydrate metabolic process GO:0044723 118 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.035
neuron neuron synaptic transmission GO:0007270 60 0.035
carbohydrate metabolic process GO:0005975 130 0.034
synaptic transmission GO:0007268 235 0.034
cellular response to cytokine stimulus GO:0071345 127 0.034
carboxylic acid transport GO:0046942 115 0.034
negative regulation of cell communication GO:0010648 158 0.034
reproduction GO:0000003 245 0.033
response to temperature stimulus GO:0009266 94 0.033
positive regulation of cell development GO:0010720 176 0.033
response to hexose GO:0009746 144 0.033
positive regulation of catalytic activity GO:0043085 184 0.032
protein complex assembly GO:0006461 263 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
organophosphate biosynthetic process GO:0090407 143 0.032
regulation of cell differentiation GO:0045595 320 0.032
response to metal ion GO:0010038 253 0.032
regulation of membrane potential GO:0042391 110 0.032
head development GO:0060322 247 0.031
positive regulation of developmental process GO:0051094 283 0.031
response to radiation GO:0009314 137 0.031
somatostatin signaling pathway GO:0038170 4 0.031
regulation of lipid biosynthetic process GO:0046890 38 0.031
limb morphogenesis GO:0035108 4 0.031
learning GO:0007612 33 0.031
regulation of purine nucleotide metabolic process GO:1900542 115 0.031
cell part morphogenesis GO:0032990 123 0.031
ribonucleotide biosynthetic process GO:0009260 85 0.031
cellular component biogenesis GO:0044085 368 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
positive regulation of secretion GO:0051047 140 0.030
establishment of anatomical structure orientation GO:0048560 1 0.030
inorganic cation transmembrane transport GO:0098662 202 0.030
regulation of ion transmembrane transport GO:0034765 121 0.030
neuron projection development GO:0031175 273 0.030
neuromuscular process GO:0050905 2 0.030
response to insulin GO:0032868 133 0.029
somatostatin receptor signaling pathway GO:0038169 4 0.029
alcohol metabolic process GO:0006066 77 0.029
membrane organization GO:0061024 94 0.029
anion transport GO:0006820 178 0.029
macromolecular complex assembly GO:0065003 273 0.029
cellular response to tumor necrosis factor GO:0071356 46 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.029
response to nutrient levels GO:0031667 370 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
learning or memory GO:0007611 90 0.028
renal system development GO:0072001 67 0.028
behavior GO:0007610 205 0.028
regulation of synaptic transmission GO:0050804 141 0.028
multicellular organism reproduction GO:0032504 233 0.027
regulation of cellular localization GO:0060341 263 0.027
establishment of organ orientation GO:0048561 1 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
nucleoside phosphate biosynthetic process GO:1901293 102 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
cell projection morphogenesis GO:0048858 123 0.027
vesicle mediated transport GO:0016192 181 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
positive regulation of cell communication GO:0010647 271 0.026
response to wounding GO:0009611 254 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
positive regulation of transferase activity GO:0051347 81 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
inorganic ion transmembrane transport GO:0098660 229 0.026
protein oligomerization GO:0051259 191 0.026
regulation of hormone secretion GO:0046883 106 0.026
purine nucleotide catabolic process GO:0006195 136 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
response to peptide GO:1901652 292 0.025
amide transport GO:0042886 105 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
regulation of ion transport GO:0043269 245 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.025
positive regulation of hormone secretion GO:0046887 65 0.025
regulation of molecular function GO:0065009 398 0.025
positive regulation of transport GO:0051050 245 0.025
response to estradiol GO:0032355 164 0.024
response to growth factor GO:0070848 189 0.024
negative regulation of developmental process GO:0051093 125 0.024
response to monosaccharide GO:0034284 159 0.024
central nervous system development GO:0007417 311 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
response to ethanol GO:0045471 162 0.024
nucleotide metabolic process GO:0009117 279 0.024
single organism organelle organization GO:1902589 180 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
protein complex biogenesis GO:0070271 263 0.023
positive regulation of nervous system development GO:0051962 178 0.023
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
hormone transport GO:0009914 121 0.022
nucleotide biosynthetic process GO:0009165 98 0.022
response to carbohydrate GO:0009743 183 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
regulation of mapk cascade GO:0043408 116 0.022
single organism reproductive process GO:0044702 297 0.022
positive regulation of molecular function GO:0044093 230 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
acid secretion GO:0046717 48 0.022
kidney development GO:0001822 67 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
response to estrogen GO:0043627 232 0.021
regulation of cell proliferation GO:0042127 359 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
regulation of adenylate cyclase activity GO:0045761 18 0.021
regulation of vasculature development GO:1901342 44 0.021
response to lipopolysaccharide GO:0032496 191 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
cellular response to stress GO:0033554 269 0.020
myeloid leukocyte differentiation GO:0002573 20 0.020
cardiovascular system development GO:0072358 134 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
positive regulation of kinase activity GO:0033674 77 0.020
regulation of neuron differentiation GO:0045664 208 0.019
neurological system process GO:0050877 219 0.019
purine containing compound catabolic process GO:0072523 138 0.019
glutamate receptor signaling pathway GO:0007215 43 0.019
organic acid transport GO:0015849 116 0.019
intracellular signal transduction GO:0035556 314 0.019
tube development GO:0035295 89 0.019
ras protein signal transduction GO:0007265 29 0.019
cell activation GO:0001775 97 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
cognition GO:0050890 92 0.018
reproductive structure development GO:0048608 128 0.018
hormone secretion GO:0046879 115 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
development of primary sexual characteristics GO:0045137 107 0.018
cell motility GO:0048870 202 0.018
chemical homeostasis GO:0048878 292 0.018
response to glucose GO:0009749 136 0.018
calcium ion homeostasis GO:0055074 162 0.018
phospholipid metabolic process GO:0006644 61 0.018
negative regulation of gene expression GO:0010629 199 0.018
regulation of cell activation GO:0050865 50 0.018
regulation of catalytic activity GO:0050790 304 0.018
cellular response to insulin stimulus GO:0032869 81 0.018
positive regulation of cellular catabolic process GO:0031331 71 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
metal ion homeostasis GO:0055065 186 0.018
cation transport GO:0006812 382 0.018
nucleoside metabolic process GO:0009116 179 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
saliva secretion GO:0046541 3 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
immune system process GO:0002376 204 0.017
organophosphate catabolic process GO:0046434 148 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
nitrogen compound transport GO:0071705 229 0.017
negative regulation of metabolic process GO:0009892 331 0.017
brain development GO:0007420 247 0.017
regulation of lyase activity GO:0051339 22 0.017
regulation of protein localization GO:0032880 81 0.016
regulation of growth GO:0040008 105 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
regulation of protein metabolic process GO:0051246 289 0.016
gland development GO:0048732 155 0.016
homeostatic process GO:0042592 331 0.016
intracellular transport GO:0046907 185 0.016
dicarboxylic acid transport GO:0006835 34 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
positive regulation of organelle organization GO:0010638 48 0.016
signal release GO:0023061 145 0.015
cell morphogenesis GO:0000902 142 0.015
cellular response to lipid GO:0071396 201 0.015
positive regulation of ion transport GO:0043270 94 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
response to acid chemical GO:0001101 222 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
cyclic nucleotide metabolic process GO:0009187 80 0.015
response to mechanical stimulus GO:0009612 134 0.015
defense response GO:0006952 194 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
rhythmic process GO:0048511 156 0.015
response to bacterium GO:0009617 200 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cellular response to external stimulus GO:0071496 118 0.015
regulation of cell projection organization GO:0031344 175 0.015
protein tetramerization GO:0051262 38 0.015
macromolecule localization GO:0033036 252 0.015
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
positive regulation of cytoskeleton organization GO:0051495 26 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
response to external biotic stimulus GO:0043207 221 0.014
cyclic nucleotide biosynthetic process GO:0009190 63 0.014
peristalsis GO:0030432 2 0.014
female gonad development GO:0008585 53 0.014
multi organism reproductive process GO:0044703 262 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
localization of cell GO:0051674 202 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
positive regulation of transmembrane transport GO:0034764 25 0.014
response to nicotine GO:0035094 51 0.014
gtp catabolic process GO:0006184 71 0.014
sex differentiation GO:0007548 113 0.014
forebrain development GO:0030900 98 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
regulation of nervous system development GO:0051960 264 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
inflammatory response GO:0006954 150 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of kinase activity GO:0043549 117 0.013
negative regulation of hormone secretion GO:0046888 46 0.013
positive regulation of protein modification process GO:0031401 142 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
appendage morphogenesis GO:0035107 4 0.013
apoptotic process GO:0006915 381 0.013
regulation of carbohydrate metabolic process GO:0006109 41 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
regulation of ossification GO:0030278 32 0.013
response to starvation GO:0042594 59 0.013
startle response GO:0001964 2 0.013
regulation of cation channel activity GO:2001257 23 0.013
nucleotide catabolic process GO:0009166 139 0.013
mapk cascade GO:0000165 140 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
tissue development GO:0009888 252 0.012
l glutamate import GO:0051938 2 0.012
vasculature development GO:0001944 70 0.012
peptide secretion GO:0002790 86 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
response to purine containing compound GO:0014074 126 0.012
response to cocaine GO:0042220 39 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
organ morphogenesis GO:0009887 75 0.012
cellular catabolic process GO:0044248 295 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
single organism behavior GO:0044708 130 0.012
nucleoside catabolic process GO:0009164 126 0.012
regulation of body fluid levels GO:0050878 90 0.012
urogenital system development GO:0001655 78 0.012
indole containing compound metabolic process GO:0042430 11 0.012
organelle organization GO:0006996 266 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
cation homeostasis GO:0055080 195 0.012
response to inorganic substance GO:0010035 377 0.012
regulation of cyclase activity GO:0031279 21 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
regulation of cellular component organization GO:0051128 368 0.012
camera type eye development GO:0043010 48 0.012
cellular ketone metabolic process GO:0042180 51 0.012
ovulation cycle process GO:0022602 50 0.012
cellular cation homeostasis GO:0030003 180 0.012
sexual reproduction GO:0019953 148 0.012
negative regulation of transport GO:0051051 136 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of apoptotic process GO:0042981 335 0.012
growth GO:0040007 165 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
negative regulation of secretion GO:0051048 82 0.011
urinary tract smooth muscle contraction GO:0014848 4 0.011
gamete generation GO:0007276 124 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of protein kinase activity GO:0045859 105 0.011
response to organophosphorus GO:0046683 102 0.011
cellular component movement GO:0006928 248 0.011
regulation of hormone levels GO:0010817 187 0.011
positive regulation of saliva secretion GO:0046878 3 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
urinary bladder smooth muscle contraction GO:0014832 4 0.011
positive regulation of synaptic transmission GO:0050806 62 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
peptide transport GO:0015833 97 0.011
regulation of amino acid transport GO:0051955 25 0.011
phasic smooth muscle contraction GO:0014821 3 0.011
regulation of neurogenesis GO:0050767 247 0.011
response to other organism GO:0051707 220 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
chemosensory behavior GO:0007635 2 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
coenzyme metabolic process GO:0006732 86 0.011
protein homooligomerization GO:0051260 91 0.011
sensory perception of light stimulus GO:0050953 3 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
regulation of insulin secretion GO:0050796 65 0.010
ventral spinal cord development GO:0021517 3 0.010
response to ammonium ion GO:0060359 71 0.010
cell cycle process GO:0022402 57 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
glycerophospholipid metabolic process GO:0006650 47 0.010
regulation of immune system process GO:0002682 123 0.010
regulation of transferase activity GO:0051338 123 0.010
lipid biosynthetic process GO:0008610 128 0.010
cell cycle GO:0007049 101 0.010
response to axon injury GO:0048678 59 0.010
regulation of leukocyte activation GO:0002694 45 0.010
cellular homeostasis GO:0019725 252 0.010
gliogenesis GO:0042063 93 0.010
heterocycle catabolic process GO:0046700 167 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010

Fgf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 0 0.041
kidney disease DOID:557 0 0.041
disease of anatomical entity DOID:7 0 0.041
urinary system disease DOID:18 0 0.041
musculoskeletal system disease DOID:17 0 0.037
connective tissue disease DOID:65 0 0.030
sensory system disease DOID:0050155 0 0.018
nervous system disease DOID:863 0 0.018
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
bone disease DOID:0080001 0 0.015
bone development disease DOID:0080006 0 0.011