Rattus norvegicus

119 known processes

Itgb2

integrin, beta 2

(Aliases: MGC116306,Cd18)

Itgb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.415
organophosphate metabolic process GO:0019637 370 0.239
immune response GO:0006955 104 0.211
neuron apoptotic process GO:0051402 88 0.176
leukocyte cell cell adhesion GO:0007159 4 0.127
cell type specific apoptotic process GO:0097285 134 0.125
single organismal cell cell adhesion GO:0016337 42 0.092
cell motility GO:0048870 202 0.087
regulation of phosphate metabolic process GO:0019220 349 0.086
Rat
positive regulation of response to stimulus GO:0048584 285 0.083
Rat
immune response activating signal transduction GO:0002757 15 0.081
cytoskeleton organization GO:0007010 111 0.078
purine containing compound metabolic process GO:0072521 253 0.072
positive regulation of phosphate metabolic process GO:0045937 262 0.071
Rat
negative regulation of response to tumor cell GO:0002835 2 0.070
regulation of cellular component organization GO:0051128 368 0.068
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.068
Rat
regulation of protein metabolic process GO:0051246 289 0.066
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.065
Rat
establishment of protein localization GO:0045184 141 0.064
Rat
multicellular organism reproduction GO:0032504 233 0.062
Rat
purine ribonucleotide catabolic process GO:0009154 136 0.062
programmed cell death GO:0012501 392 0.061
nucleobase containing small molecule metabolic process GO:0055086 316 0.060
purine containing compound catabolic process GO:0072523 138 0.060
regulation of signal transduction GO:0009966 318 0.060
Rat
regulation of programmed cell death GO:0043067 341 0.058
protein complex biogenesis GO:0070271 263 0.058
apoptotic process GO:0006915 381 0.057
regulation of cell migration GO:0030334 128 0.056
Rat
positive regulation of biosynthetic process GO:0009891 319 0.054
regulation of immune system process GO:0002682 123 0.053
cell activation GO:0001775 97 0.053
anatomical structure morphogenesis GO:0009653 298 0.052
cellular component assembly GO:0022607 360 0.052
Rat
vesicle mediated transport GO:0016192 181 0.052
Rat
intracellular signal transduction GO:0035556 314 0.049
Rat
locomotion GO:0040011 237 0.048
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.048
regulation of neuron apoptotic process GO:0043523 83 0.046
cell migration GO:0016477 197 0.046
nucleotide metabolic process GO:0009117 279 0.046
cellular component biogenesis GO:0044085 368 0.046
Rat
defense response GO:0006952 194 0.045
regulation of apoptotic process GO:0042981 335 0.045
protein complex subunit organization GO:0071822 302 0.045
protein complex assembly GO:0006461 263 0.044
carbohydrate derivative catabolic process GO:1901136 147 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.042
regulation of phosphorylation GO:0042325 248 0.042
Rat
guanosine containing compound metabolic process GO:1901068 74 0.041
organic acid metabolic process GO:0006082 292 0.041
positive regulation of signaling GO:0023056 270 0.040
Rat
positive regulation of cell communication GO:0010647 271 0.040
Rat
neuron differentiation GO:0030182 368 0.038
Rat
cell projection morphogenesis GO:0048858 123 0.038
localization of cell GO:0051674 202 0.038
regulation of anatomical structure size GO:0090066 135 0.038
single organism catabolic process GO:0044712 283 0.037
activation of immune response GO:0002253 26 0.036
nucleoside catabolic process GO:0009164 126 0.036
single organism cell adhesion GO:0098602 46 0.036
nucleoside phosphate catabolic process GO:1901292 140 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
Rat
cell activation involved in immune response GO:0002263 16 0.035
gtp catabolic process GO:0006184 71 0.035
behavior GO:0007610 205 0.034
regulation of cell development GO:0060284 263 0.034
Rat
cell cell signaling GO:0007267 335 0.034
single organism cellular localization GO:1902580 102 0.034
ribonucleoside triphosphate metabolic process GO:0009199 141 0.034
head development GO:0060322 247 0.033
muscle structure development GO:0061061 87 0.033
single organism organelle organization GO:1902589 180 0.033
regulation of catalytic activity GO:0050790 304 0.033
cellular component movement GO:0006928 248 0.033
ribonucleoside triphosphate catabolic process GO:0009203 122 0.032
regulation of protein phosphorylation GO:0001932 183 0.032
Rat
purine nucleotide metabolic process GO:0006163 229 0.031
organonitrogen compound catabolic process GO:1901565 179 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
Rat
regulation of neuron projection development GO:0010975 161 0.031
Rat
purine nucleotide catabolic process GO:0006195 136 0.031
positive regulation of phosphorylation GO:0042327 177 0.031
Rat
dephosphorylation GO:0016311 98 0.030
neuron projection development GO:0031175 273 0.030
Rat
cell projection organization GO:0030030 302 0.030
Rat
positive regulation of neurogenesis GO:0050769 165 0.030
Rat
positive regulation of transport GO:0051050 245 0.029
Rat
macromolecular complex assembly GO:0065003 273 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
Rat
endocytosis GO:0006897 84 0.029
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.029
reproduction GO:0000003 245 0.028
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.028
ras protein signal transduction GO:0007265 29 0.028
neuron projection morphogenesis GO:0048812 122 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
positive regulation of apoptotic process GO:0043065 154 0.028
salivary gland development GO:0007431 3 0.027
guanosine containing compound catabolic process GO:1901069 71 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
protein phosphorylation GO:0006468 345 0.027
Rat
positive regulation of hydrolase activity GO:0051345 86 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
biological adhesion GO:0022610 110 0.026
actin filament organization GO:0007015 42 0.026
actin cytoskeleton organization GO:0030036 73 0.026
nucleotide catabolic process GO:0009166 139 0.025
positive regulation of neuron apoptotic process GO:0043525 33 0.025
multi organism reproductive process GO:0044703 262 0.025
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.025
Rat
regulation of system process GO:0044057 208 0.025
ribonucleotide catabolic process GO:0009261 136 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
nucleoside triphosphate catabolic process GO:0009143 123 0.025
purine nucleoside triphosphate catabolic process GO:0009146 122 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
negative regulation of metabolic process GO:0009892 331 0.024
regulation of neuron death GO:1901214 115 0.024
central nervous system development GO:0007417 311 0.024
purine nucleoside triphosphate metabolic process GO:0009144 141 0.024
regulation of muscle contraction GO:0006937 53 0.024
heterocycle catabolic process GO:0046700 167 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
Rat
organelle organization GO:0006996 266 0.024
regulation of locomotion GO:0040012 148 0.024
Rat
cell part morphogenesis GO:0032990 123 0.023
muscle system process GO:0003012 115 0.023
regulation of molecular function GO:0065009 398 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.022
regulation of tube size GO:0035150 89 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
cell chemotaxis GO:0060326 31 0.022
protein transport GO:0015031 132 0.021
Rat
glycosyl compound metabolic process GO:1901657 182 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
cell adhesion GO:0007155 110 0.021
regulation of hydrolase activity GO:0051336 143 0.021
gtp metabolic process GO:0046039 72 0.021
brain development GO:0007420 247 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
response to amine GO:0014075 46 0.021
response to wounding GO:0009611 254 0.021
regulation of neurogenesis GO:0050767 247 0.021
Rat
macromolecule localization GO:0033036 252 0.020
Rat
feeding behavior GO:0007631 53 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
cellular protein complex assembly GO:0043623 44 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
cellular catabolic process GO:0044248 295 0.020
reproductive process GO:0022414 372 0.020
Rat
cell substrate adhesion GO:0031589 29 0.020
Rat
aromatic compound catabolic process GO:0019439 168 0.020
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
Rat
hematopoietic progenitor cell differentiation GO:0002244 2 0.020
muscle cell proliferation GO:0033002 84 0.020
cell junction maintenance GO:0034331 1 0.020
glycerolipid metabolic process GO:0046486 67 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
regulation of intracellular signal transduction GO:1902531 218 0.019
Rat
signal release GO:0023061 145 0.019
sensory perception GO:0007600 101 0.019
regulation of cellular component size GO:0032535 51 0.019
single organism reproductive process GO:0044702 297 0.019
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of gtp catabolic process GO:0033124 58 0.019
secretion GO:0046903 307 0.019
negative regulation of immune response to tumor cell GO:0002838 2 0.019
response to hypoxia GO:0001666 231 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
organic substance catabolic process GO:1901575 316 0.019
purine nucleoside metabolic process GO:0042278 169 0.018
regulation of rna metabolic process GO:0051252 391 0.018
regulation of secretion by cell GO:1903530 208 0.018
positive regulation of transcription factor import into nucleus GO:0042993 4 0.018
regulation of transferase activity GO:0051338 123 0.018
response to cgmp GO:0070305 3 0.018
regulation of cell projection organization GO:0031344 175 0.018
Rat
positive regulation of molecular function GO:0044093 230 0.018
regulation of phagocytosis engulfment GO:0060099 4 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
negative regulation of innate immune response GO:0045824 4 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
developmental process involved in reproduction GO:0003006 159 0.017
positive regulation of cell motility GO:2000147 97 0.017
Rat
negative regulation of response to stimulus GO:0048585 155 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
response to inorganic substance GO:0010035 377 0.017
neuron development GO:0048666 286 0.017
Rat
striated muscle tissue development GO:0014706 58 0.016
protein heterooligomerization GO:0051291 89 0.016
cellular component maintenance GO:0043954 4 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
positive regulation of immune response GO:0050778 42 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
nucleoside metabolic process GO:0009116 179 0.016
response to oxygen levels GO:0070482 265 0.016
neuron death GO:0070997 127 0.016
regulation of protein modification process GO:0031399 194 0.016
Rat
positive regulation of phagocytosis engulfment GO:0060100 4 0.016
regulation of cell differentiation GO:0045595 320 0.016
Rat
sexual reproduction GO:0019953 148 0.016
lymphocyte activation GO:0046649 43 0.016
regulation of transcription dna templated GO:0006355 374 0.016
regulation of cell motility GO:2000145 131 0.016
Rat
protein polymerization GO:0051258 22 0.016
endoplasmic reticulum to cytosol transport GO:1903513 4 0.016
protein localization GO:0008104 191 0.016
Rat
rho protein signal transduction GO:0007266 11 0.015
salivary gland morphogenesis GO:0007435 1 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
cellular ketone metabolic process GO:0042180 51 0.015
amine metabolic process GO:0009308 38 0.015
regulation of cellular extravasation GO:0002691 2 0.015
response to decreased oxygen levels GO:0036293 237 0.015
membrane organization GO:0061024 94 0.015
Rat
axis specification GO:0009798 4 0.015
gamete generation GO:0007276 124 0.015
skin morphogenesis GO:0043589 2 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
positive regulation of signal transduction GO:0009967 175 0.015
Rat
gland development GO:0048732 155 0.014
myoblast fusion GO:0007520 2 0.014
regulation of cellular component movement GO:0051270 150 0.014
Rat
inflammatory response GO:0006954 150 0.014
circulatory system process GO:0003013 183 0.014
actin filament based process GO:0030029 86 0.014
regulation of cellular localization GO:0060341 263 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
response to acid chemical GO:0001101 222 0.014
anterior posterior pattern specification GO:0009952 1 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
smooth muscle contraction GO:0006939 37 0.014
hormone secretion GO:0046879 115 0.014
regulation of neuron differentiation GO:0045664 208 0.013
Rat
mast cell chemotaxis GO:0002551 4 0.013
muscle contraction GO:0006936 88 0.013
platelet aggregation GO:0070527 4 0.013
cellular macromolecular complex assembly GO:0034622 58 0.013
regulation of response to stress GO:0080134 126 0.013
neurological system process GO:0050877 219 0.013
rna metabolic process GO:0016070 406 0.013
mapk cascade GO:0000165 140 0.013
Rat
negative regulation of molecular function GO:0044092 133 0.013
negative regulation of signal transduction GO:0009968 83 0.013
epithelial cell migration GO:0010631 19 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
Rat
homeostatic process GO:0042592 331 0.013
Rat
blood circulation GO:0008015 183 0.013
sensory perception of pain GO:0019233 73 0.013
regulation of actin filament based process GO:0032970 42 0.013
regulation of protein complex assembly GO:0043254 33 0.013
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.013
mast cell migration GO:0097531 4 0.013
immune response regulating signaling pathway GO:0002764 19 0.013
actin filament polymerization GO:0030041 11 0.013
lipid metabolic process GO:0006629 283 0.013
cellular component morphogenesis GO:0032989 155 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
Rat
intracellular protein transport GO:0006886 79 0.012
Rat
cellular amine metabolic process GO:0044106 38 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of mapk cascade GO:0043408 116 0.012
Rat
dendrite development GO:0016358 72 0.012
rna localization GO:0006403 4 0.012
calcium ion homeostasis GO:0055074 162 0.012
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of nervous system development GO:0051960 264 0.012
Rat
response to growth factor GO:0070848 189 0.012
Rat
vascular process in circulatory system GO:0003018 96 0.012
cellular homeostasis GO:0019725 252 0.012
Rat
positive regulation of rna metabolic process GO:0051254 203 0.012
cellular macromolecule localization GO:0070727 122 0.012
Rat
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.011
response to nutrient levels GO:0031667 370 0.011
Rat
positive regulation of secretion GO:0051047 140 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of hormone levels GO:0010817 187 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of muscle system process GO:0090257 79 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
Rat
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
Rat
smooth muscle cell proliferation GO:0048659 77 0.011
autophagic cell death GO:0048102 4 0.011
cellular protein localization GO:0034613 122 0.011
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
nitrogen compound transport GO:0071705 229 0.011
lipid storage GO:0019915 1 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
chemical homeostasis GO:0048878 292 0.011
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.011
cognition GO:0050890 92 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
leukocyte activation involved in immune response GO:0002366 16 0.011
rna biosynthetic process GO:0032774 380 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of cell adhesion GO:0030155 52 0.011
Rat
alpha beta t cell activation GO:0046631 3 0.011
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.011
leukocyte activation GO:0045321 76 0.011
cellular response to alcohol GO:0097306 87 0.011
Rat
catabolic process GO:0009056 351 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
positive regulation of immune system process GO:0002684 90 0.010
single organism biosynthetic process GO:0044711 342 0.010
regulation of smooth muscle contraction GO:0006940 29 0.010
embryonic pattern specification GO:0009880 1 0.010
alcohol metabolic process GO:0006066 77 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
Rat
actin filament bundle assembly GO:0051017 19 0.010
triglyceride homeostasis GO:0070328 2 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010
synaptic transmission GO:0007268 235 0.010
actin polymerization or depolymerization GO:0008154 14 0.010
regulation of gtpase activity GO:0043087 57 0.010
positive regulation of organelle organization GO:0010638 48 0.010

Itgb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org