Rattus norvegicus

146 known processes

Flt3

fms-related tyrosine kinase 3

Flt3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to hormone stimulus GO:0032870 247 0.087
locomotion GO:0040011 237 0.081
Rat
cellular response to lipid GO:0071396 201 0.067
regulation of phosphate metabolic process GO:0019220 349 0.066
cellular response to organic cyclic compound GO:0071407 202 0.065
cell motility GO:0048870 202 0.062
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.061
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.059
positive regulation of cell differentiation GO:0045597 217 0.057
Rat
signal transduction by phosphorylation GO:0023014 144 0.057
Rat
regulation of cell migration GO:0030334 128 0.056
Rat
positive regulation of developmental process GO:0051094 283 0.056
Rat
regulation of nervous system development GO:0051960 264 0.056
Rat
aging GO:0007568 241 0.055
cellular response to peptide GO:1901653 133 0.054
regulation of molecular function GO:0065009 398 0.052
Rat
regulation of phosphorylation GO:0042325 248 0.051
mapk cascade GO:0000165 140 0.051
Rat
regulation of immune system process GO:0002682 123 0.051
localization of cell GO:0051674 202 0.049
Rat
biological adhesion GO:0022610 110 0.048
regulation of cell proliferation GO:0042127 359 0.048
positive regulation of cell motility GO:2000147 97 0.048
Rat
positive regulation of cell proliferation GO:0008284 249 0.048
Rat
reproductive process GO:0022414 372 0.047
Rat
cellular response to nitrogen compound GO:1901699 210 0.045
growth GO:0040007 165 0.044
Rat
rna metabolic process GO:0016070 406 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
Rat
cell migration GO:0016477 197 0.044
Rat
regulation of intracellular signal transduction GO:1902531 218 0.043
Rat
response to oxygen levels GO:0070482 265 0.043
Rat
epithelium development GO:0060429 96 0.043
response to radiation GO:0009314 137 0.043
Rat
cellular component movement GO:0006928 248 0.043
Rat
tissue development GO:0009888 252 0.042
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
regulation of rna biosynthetic process GO:2001141 381 0.041
purine nucleotide metabolic process GO:0006163 229 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.040
cellular response to organonitrogen compound GO:0071417 197 0.040
wound healing GO:0042060 122 0.040
Rat
regulation of rna metabolic process GO:0051252 391 0.040
regulation of mapk cascade GO:0043408 116 0.039
Rat
positive regulation of biosynthetic process GO:0009891 319 0.039
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.039
regulation of system process GO:0044057 208 0.038
Rat
neuron projection development GO:0031175 273 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
gastrulation GO:0007369 2 0.037
regulation of apoptotic process GO:0042981 335 0.037
Rat
response to mechanical stimulus GO:0009612 134 0.037
regulation of protein phosphorylation GO:0001932 183 0.036
response to metal ion GO:0010038 253 0.036
macromolecular complex subunit organization GO:0043933 339 0.035
tube development GO:0035295 89 0.034
inflammatory response GO:0006954 150 0.034
regulation of anatomical structure morphogenesis GO:0022603 141 0.033
response to retinoic acid GO:0032526 63 0.033
Rat
regulation of programmed cell death GO:0043067 341 0.033
Rat
brain development GO:0007420 247 0.033
regulation of cell development GO:0060284 263 0.032
Rat
organophosphate metabolic process GO:0019637 370 0.032
cellular response to peptide hormone stimulus GO:0071375 120 0.032
response to inorganic substance GO:0010035 377 0.032
Rat
circulatory system process GO:0003013 183 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
macromolecule localization GO:0033036 252 0.031
cytoskeleton organization GO:0007010 111 0.031
cellular response to stress GO:0033554 269 0.031
organonitrogen compound catabolic process GO:1901565 179 0.031
response to oxidative stress GO:0006979 186 0.031
Rat
positive regulation of response to stimulus GO:0048584 285 0.030
Rat
blood circulation GO:0008015 183 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
single organism reproductive process GO:0044702 297 0.029
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
Rat
anatomical structure morphogenesis GO:0009653 298 0.029
Rat
synaptic transmission GO:0007268 235 0.028
Rat
regulation of cell differentiation GO:0045595 320 0.028
cellular component assembly GO:0022607 360 0.028
Rat
protein phosphorylation GO:0006468 345 0.028
regulation of cell motility GO:2000145 131 0.028
Rat
intracellular signal transduction GO:0035556 314 0.028
Rat
cellular component biogenesis GO:0044085 368 0.028
Rat
response to estradiol GO:0032355 164 0.028
Rat
head development GO:0060322 247 0.027
positive regulation of nucleotide metabolic process GO:0045981 91 0.027
purine containing compound metabolic process GO:0072521 253 0.027
cellular component morphogenesis GO:0032989 155 0.027
nucleotide metabolic process GO:0009117 279 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
regeneration GO:0031099 163 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
cell adhesion GO:0007155 110 0.026
positive regulation of cell development GO:0010720 176 0.026
Rat
muscle cell proliferation GO:0033002 84 0.026
Rat
response to peptide GO:1901652 292 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
apoptotic process GO:0006915 381 0.026
Rat
multi organism reproductive process GO:0044703 262 0.025
Rat
response to corticosteroid GO:0031960 235 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
regulation of cellular component movement GO:0051270 150 0.025
Rat
regulation of neurogenesis GO:0050767 247 0.025
Rat
regulation of membrane potential GO:0042391 110 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
cell projection organization GO:0030030 302 0.024
Rat
neuron differentiation GO:0030182 368 0.024
neurological system process GO:0050877 219 0.024
Rat
protein localization GO:0008104 191 0.024
multicellular organism reproduction GO:0032504 233 0.024
Rat
positive regulation of transport GO:0051050 245 0.024
nucleoside metabolic process GO:0009116 179 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
transcription dna templated GO:0006351 377 0.023
protein complex subunit organization GO:0071822 302 0.023
regulation of cellular localization GO:0060341 263 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
Rat
positive regulation of apoptotic process GO:0043065 154 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
aromatic compound catabolic process GO:0019439 168 0.022
positive regulation of cell death GO:0010942 184 0.022
central nervous system development GO:0007417 311 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
carbohydrate derivative biosynthetic process GO:1901137 124 0.022
Rat
response to acid chemical GO:0001101 222 0.022
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.022
cell morphogenesis GO:0000902 142 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
response to toxic substance GO:0009636 133 0.022
Rat
positive regulation of phosphorylation GO:0042327 177 0.021
heterocycle catabolic process GO:0046700 167 0.021
positive regulation of cell communication GO:0010647 271 0.021
Rat
response to cytokine GO:0034097 215 0.021
immune response GO:0006955 104 0.021
regulation of catalytic activity GO:0050790 304 0.021
Rat
programmed cell death GO:0012501 392 0.021
Rat
regulation of locomotion GO:0040012 148 0.021
Rat
response to reactive oxygen species GO:0000302 120 0.021
Rat
regulation of transcription dna templated GO:0006355 374 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
response to peptide hormone GO:0043434 278 0.020
reproduction GO:0000003 245 0.020
Rat
ras protein signal transduction GO:0007265 29 0.020
positive regulation of molecular function GO:0044093 230 0.020
Rat
neuron development GO:0048666 286 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
limb morphogenesis GO:0035108 4 0.020
response to external biotic stimulus GO:0043207 221 0.020
regulation of protein modification process GO:0031399 194 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
Rat
response to hypoxia GO:0001666 231 0.019
Rat
ribonucleoside catabolic process GO:0042454 126 0.019
cell activation GO:0001775 97 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
cell cell signaling GO:0007267 335 0.019
Rat
response to nutrient levels GO:0031667 370 0.019
amine metabolic process GO:0009308 38 0.019
regulation of response to stress GO:0080134 126 0.019
cellular response to alcohol GO:0097306 87 0.019
oxoacid metabolic process GO:0043436 290 0.019
purine containing compound catabolic process GO:0072523 138 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
regulation of neuron differentiation GO:0045664 208 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
Rat
embryonic limb morphogenesis GO:0030326 4 0.019
rna biosynthetic process GO:0032774 380 0.019
regulation of vasculature development GO:1901342 44 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
regulation of signal transduction GO:0009966 318 0.018
Rat
organelle organization GO:0006996 266 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
action potential GO:0001508 54 0.018
cellular catabolic process GO:0044248 295 0.018
response to increased oxygen levels GO:0036296 45 0.018
Rat
regulation of secretion GO:0051046 224 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
Rat
leukocyte migration GO:0050900 38 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
Rat
single organism organelle organization GO:1902589 180 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
cellular amine metabolic process GO:0044106 38 0.017
immune system process GO:0002376 204 0.017
response to estrogen GO:0043627 232 0.017
Rat
catabolic process GO:0009056 351 0.017
peptidyl amino acid modification GO:0018193 126 0.017
positive regulation of immune system process GO:0002684 90 0.017
Rat
positive regulation of catalytic activity GO:0043085 184 0.017
Rat
regulation of cellular response to stress GO:0080135 49 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
circulatory system development GO:0072359 134 0.016
nucleic acid templated transcription GO:0097659 379 0.016
sexual reproduction GO:0019953 148 0.016
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
appendage morphogenesis GO:0035107 4 0.016
positive regulation of nervous system development GO:0051962 178 0.016
Rat
embryonic skeletal system morphogenesis GO:0048704 3 0.016
anterior posterior pattern specification GO:0009952 1 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
erk1 and erk2 cascade GO:0070371 48 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
Rat
vascular process in circulatory system GO:0003018 96 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
response to wounding GO:0009611 254 0.016
Rat
regulation of anatomical structure size GO:0090066 135 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
gamete generation GO:0007276 124 0.016
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
protein complex biogenesis GO:0070271 263 0.015
secretion by cell GO:0032940 248 0.015
single organism biosynthetic process GO:0044711 342 0.015
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
Rat
negative regulation of apoptotic process GO:0043066 181 0.015
Rat
regulation of transferase activity GO:0051338 123 0.015
Rat
purine nucleoside metabolic process GO:0042278 169 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
single organism cell adhesion GO:0098602 46 0.015
cellular response to external stimulus GO:0071496 118 0.015
establishment of protein localization GO:0045184 141 0.015
motor neuron axon guidance GO:0008045 1 0.014
organ regeneration GO:0031100 101 0.014
negative regulation of developmental process GO:0051093 125 0.014
morphogenesis of an epithelium GO:0002009 20 0.014
macromolecular complex assembly GO:0065003 273 0.014
protein autophosphorylation GO:0046777 66 0.014
muscle structure development GO:0061061 87 0.014
Rat
positive regulation of protein metabolic process GO:0051247 178 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
cellular protein localization GO:0034613 122 0.014
multi multicellular organism process GO:0044706 138 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
regulation of blood circulation GO:1903522 110 0.014
positive regulation of signaling GO:0023056 270 0.014
Rat
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
positive regulation of cell migration GO:0030335 96 0.014
Rat
saliva secretion GO:0046541 3 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
axon development GO:0061564 96 0.014
positive regulation of signal transduction GO:0009967 175 0.014
Rat
tissue remodeling GO:0048771 40 0.014
Rat
kidney development GO:0001822 67 0.014
Rat
embryonic appendage morphogenesis GO:0035113 4 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
cellular chemical homeostasis GO:0055082 247 0.014
organic acid metabolic process GO:0006082 292 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
Rat
positive regulation of protein modification process GO:0031401 142 0.013
cation homeostasis GO:0055080 195 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
stress activated protein kinase signaling cascade GO:0031098 37 0.013
epithelial cell proliferation GO:0050673 54 0.013
Rat
nucleoside triphosphate catabolic process GO:0009143 123 0.013
cytoplasmic transport GO:0016482 115 0.013
immune system development GO:0002520 41 0.013
response to glucocorticoid GO:0051384 223 0.013
positive regulation of gene expression GO:0010628 244 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cellular ketone metabolic process GO:0042180 51 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
response to hyperoxia GO:0055093 45 0.013
Rat
regulation of establishment of planar polarity GO:0090175 2 0.013
regulation of protein transport GO:0051223 68 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
learning or memory GO:0007611 90 0.013
Rat
regulation of nucleotide catabolic process GO:0030811 65 0.013
rho protein signal transduction GO:0007266 11 0.013
homeostatic process GO:0042592 331 0.013
regulation of angiogenesis GO:0045765 39 0.013
female pregnancy GO:0007565 122 0.013
nitrogen compound transport GO:0071705 229 0.013
urogenital system development GO:0001655 78 0.013
Rat
negative regulation of rna metabolic process GO:0051253 123 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
Rat
regulation of muscle contraction GO:0006937 53 0.012
Rat
liver development GO:0001889 90 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of kinase activity GO:0043549 117 0.012
Rat
peptidyl tyrosine modification GO:0018212 72 0.012
regulation of protein localization GO:0032880 81 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
Rat
negative regulation of gene expression GO:0010629 199 0.012
response to other organism GO:0051707 220 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
behavior GO:0007610 205 0.012
Rat
regulation of hydrolase activity GO:0051336 143 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
taxis GO:0042330 67 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
formation of primary germ layer GO:0001704 1 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
muscle tissue development GO:0060537 58 0.012
Rat
regulation of epithelial cell proliferation GO:0050678 49 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
Rat
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of locomotion GO:0040017 102 0.012
Rat
cytokine production GO:0001816 61 0.012
mesoderm development GO:0007498 2 0.012
salivary gland morphogenesis GO:0007435 1 0.011
skeletal system development GO:0001501 41 0.011
gland development GO:0048732 155 0.011
sodium ion transport GO:0006814 82 0.011
positive regulation of angiogenesis GO:0045766 28 0.011
stress activated mapk cascade GO:0051403 35 0.011
palate development GO:0060021 2 0.011
single organismal cell cell adhesion GO:0016337 42 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
regulation of vasoconstriction GO:0019229 44 0.011
organic substance catabolic process GO:1901575 316 0.011
regulation of neuron projection development GO:0010975 161 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
regulation of catabolic process GO:0009894 113 0.011
response to glucose GO:0009749 136 0.011
response to biotic stimulus GO:0009607 226 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of response to wounding GO:1903034 69 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
regulation of protein kinase activity GO:0045859 105 0.011
Rat
developmental growth GO:0048589 100 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
lymphoid progenitor cell differentiation GO:0002320 2 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.011
Rat
response to carbohydrate GO:0009743 183 0.011
activation of protein kinase activity GO:0032147 47 0.011
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.011
organophosphate catabolic process GO:0046434 148 0.011
negative regulation of metabolic process GO:0009892 331 0.011
response to hexose GO:0009746 144 0.011
atp metabolic process GO:0046034 72 0.011
neuron projection morphogenesis GO:0048812 122 0.011
positive regulation of neuron apoptotic process GO:0043525 33 0.011
axis specification GO:0009798 4 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
response to alkaloid GO:0043279 132 0.010
protein complex assembly GO:0006461 263 0.010
reproductive structure development GO:0048608 128 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
regulation of cell growth GO:0001558 85 0.010
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.010
response to ketone GO:1901654 182 0.010
protein transport GO:0015031 132 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
endocytosis GO:0006897 84 0.010
developmental process involved in reproduction GO:0003006 159 0.010
male gamete generation GO:0048232 99 0.010
Rat
jnk cascade GO:0007254 28 0.010

Flt3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
musculoskeletal system disease DOID:17 0 0.026
nervous system disease DOID:863 0 0.011
connective tissue disease DOID:65 0 0.010