Rattus norvegicus

0 known processes

Cpa2

carboxypeptidase A2 (pancreatic)

Cpa2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.136
response to extracellular stimulus GO:0009991 380 0.089
response to nutrient GO:0007584 248 0.087
oxoacid metabolic process GO:0043436 290 0.082
response to inorganic substance GO:0010035 377 0.076
single organism biosynthetic process GO:0044711 342 0.070
response to metal ion GO:0010038 253 0.068
carboxylic acid metabolic process GO:0019752 289 0.064
regulation of molecular function GO:0065009 398 0.062
positive regulation of cell proliferation GO:0008284 249 0.061
tissue development GO:0009888 252 0.060
regulation of catalytic activity GO:0050790 304 0.056
anatomical structure morphogenesis GO:0009653 298 0.053
Rat
cellular component assembly GO:0022607 360 0.052
carbohydrate derivative metabolic process GO:1901135 346 0.051
catabolic process GO:0009056 351 0.051
single organism catabolic process GO:0044712 283 0.050
regulation of cellular component organization GO:0051128 368 0.048
Rat
cellular amino acid metabolic process GO:0006520 107 0.046
nucleobase containing small molecule metabolic process GO:0055086 316 0.045
response to nutrient levels GO:0031667 370 0.043
cellular catabolic process GO:0044248 295 0.042
cell cell signaling GO:0007267 335 0.041
protein phosphorylation GO:0006468 345 0.040
nucleotide metabolic process GO:0009117 279 0.039
apoptotic process GO:0006915 381 0.038
response to glucocorticoid GO:0051384 223 0.038
cellular response to oxygen containing compound GO:1901701 386 0.038
Rat
blood circulation GO:0008015 183 0.037
cellular amine metabolic process GO:0044106 38 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
ribose phosphate metabolic process GO:0019693 235 0.037
organophosphate metabolic process GO:0019637 370 0.036
central nervous system development GO:0007417 311 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
cell projection organization GO:0030030 302 0.036
organelle organization GO:0006996 266 0.036
metal ion transport GO:0030001 289 0.036
neuron differentiation GO:0030182 368 0.036
regulation of cellular localization GO:0060341 263 0.036
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.036
programmed cell death GO:0012501 392 0.035
purine containing compound metabolic process GO:0072521 253 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
response to carbohydrate GO:0009743 183 0.035
Rat
ion transmembrane transport GO:0034220 365 0.035
regulation of multicellular organismal development GO:2000026 376 0.034
Rat
reproductive process GO:0022414 372 0.034
regulation of phosphate metabolic process GO:0019220 349 0.033
response to acid chemical GO:0001101 222 0.033
positive regulation of molecular function GO:0044093 230 0.033
cellular response to stress GO:0033554 269 0.032
amine metabolic process GO:0009308 38 0.032
regulation of secretion GO:0051046 224 0.032
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
cellular component biogenesis GO:0044085 368 0.032
regeneration GO:0031099 163 0.031
Rat
neurological system process GO:0050877 219 0.031
organic substance catabolic process GO:1901575 316 0.031
cellular component movement GO:0006928 248 0.030
purine nucleotide metabolic process GO:0006163 229 0.030
head development GO:0060322 247 0.030
response to wounding GO:0009611 254 0.030
Rat
regulation of apoptotic process GO:0042981 335 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
response to peptide hormone GO:0043434 278 0.029
organonitrogen compound biosynthetic process GO:1901566 167 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
response to estrogen GO:0043627 232 0.029
purine nucleoside metabolic process GO:0042278 169 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
secretion GO:0046903 307 0.028
Rat
rna biosynthetic process GO:0032774 380 0.028
response to hypoxia GO:0001666 231 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
response to estradiol GO:0032355 164 0.028
homeostatic process GO:0042592 331 0.028
Rat
neuron development GO:0048666 286 0.028
response to monosaccharide GO:0034284 159 0.027
Rat
regulation of cell proliferation GO:0042127 359 0.027
Rat
secretion by cell GO:0032940 248 0.027
Rat
synaptic transmission GO:0007268 235 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
rna metabolic process GO:0016070 406 0.027
transcription dna templated GO:0006351 377 0.027
response to peptide GO:1901652 292 0.026
single organism reproductive process GO:0044702 297 0.026
cellular lipid metabolic process GO:0044255 208 0.026
regulation of rna metabolic process GO:0051252 391 0.026
regulation of system process GO:0044057 208 0.026
intracellular transport GO:0046907 185 0.026
nitrogen compound transport GO:0071705 229 0.026
regulation of cell differentiation GO:0045595 320 0.026
cellular response to hormone stimulus GO:0032870 247 0.025
cellular ketone metabolic process GO:0042180 51 0.025
regulation of cell development GO:0060284 263 0.025
response to corticosteroid GO:0031960 235 0.025
response to purine containing compound GO:0014074 126 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
negative regulation of metabolic process GO:0009892 331 0.025
Rat
cation transport GO:0006812 382 0.025
neuron projection development GO:0031175 273 0.025
regulation of programmed cell death GO:0043067 341 0.024
organophosphate catabolic process GO:0046434 148 0.024
regulation of neurogenesis GO:0050767 247 0.024
ribonucleoside metabolic process GO:0009119 174 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
organonitrogen compound catabolic process GO:1901565 179 0.023
regulation of protein modification process GO:0031399 194 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
regulation of anatomical structure size GO:0090066 135 0.023
divalent metal ion transport GO:0070838 132 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
reproduction GO:0000003 245 0.022
positive regulation of transport GO:0051050 245 0.022
Rat
locomotion GO:0040011 237 0.022
single organism intracellular transport GO:1902582 166 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
brain development GO:0007420 247 0.022
nucleic acid templated transcription GO:0097659 379 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
regulation of protein metabolic process GO:0051246 289 0.021
Rat
response to decreased oxygen levels GO:0036293 237 0.021
multi organism reproductive process GO:0044703 262 0.021
aging GO:0007568 241 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
carbohydrate metabolic process GO:0005975 130 0.021
lipid metabolic process GO:0006629 283 0.021
small molecule biosynthetic process GO:0044283 124 0.021
heterocycle catabolic process GO:0046700 167 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
response to hexose GO:0009746 144 0.021
Rat
circulatory system process GO:0003013 183 0.021
regulation of secretion by cell GO:1903530 208 0.021
Rat
macromolecular complex assembly GO:0065003 273 0.021
response to glucose GO:0009749 136 0.021
Rat
proteolysis GO:0006508 175 0.020
Human Rat
regulation of neuron differentiation GO:0045664 208 0.020
regulation of phosphorylation GO:0042325 248 0.020
cellular homeostasis GO:0019725 252 0.020
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.020
negative regulation of cell death GO:0060548 229 0.020
ion homeostasis GO:0050801 212 0.020
localization of cell GO:0051674 202 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
cellular component morphogenesis GO:0032989 155 0.020
regulation of membrane potential GO:0042391 110 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
response to ethanol GO:0045471 162 0.020
intracellular signal transduction GO:0035556 314 0.020
transmembrane transport GO:0055085 412 0.020
growth GO:0040007 165 0.020
cellular response to nitrogen compound GO:1901699 210 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
response to vitamin GO:0033273 131 0.019
protein complex biogenesis GO:0070271 263 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
Rat
aromatic compound catabolic process GO:0019439 168 0.019
response to cytokine GO:0034097 215 0.019
regulation of cell projection organization GO:0031344 175 0.019
divalent inorganic cation transport GO:0072511 134 0.019
gland development GO:0048732 155 0.019
Rat
response to ketone GO:1901654 182 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
regulation of calcium ion transport GO:0051924 77 0.018
regulation of hormone levels GO:0010817 187 0.018
negative regulation of signaling GO:0023057 157 0.018
nucleoside metabolic process GO:0009116 179 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
purine containing compound catabolic process GO:0072523 138 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
multicellular organism reproduction GO:0032504 233 0.018
rhythmic process GO:0048511 156 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
macromolecule localization GO:0033036 252 0.017
calcium ion transport GO:0006816 131 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
organic acid biosynthetic process GO:0016053 83 0.017
negative regulation of gene expression GO:0010629 199 0.017
Rat
organic cyclic compound catabolic process GO:1901361 175 0.017
acrosome assembly GO:0001675 3 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
response to oxygen levels GO:0070482 265 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
alcohol metabolic process GO:0006066 77 0.017
fatty acid metabolic process GO:0006631 99 0.017
cytoplasmic transport GO:0016482 115 0.017
regulation of synaptic transmission GO:0050804 141 0.017
vascular process in circulatory system GO:0003018 96 0.017
negative regulation of molecular function GO:0044092 133 0.017
glycosyl compound catabolic process GO:1901658 126 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of ion transport GO:0043269 245 0.016
regulation of blood vessel size GO:0050880 89 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
regulation of signal transduction GO:0009966 318 0.016
regulation of nervous system development GO:0051960 264 0.016
response to amino acid GO:0043200 75 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of cellular component movement GO:0051270 150 0.016
negative regulation of transport GO:0051051 136 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
regulation of kinase activity GO:0043549 117 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
regulation of hydrolase activity GO:0051336 143 0.016
positive regulation of cell development GO:0010720 176 0.016
single organism organelle organization GO:1902589 180 0.016
behavior GO:0007610 205 0.016
response to camp GO:0051591 91 0.016
regulation of blood circulation GO:1903522 110 0.016
protein complex assembly GO:0006461 263 0.016
nucleoside catabolic process GO:0009164 126 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.015
protein oligomerization GO:0051259 191 0.015
lipid biosynthetic process GO:0008610 128 0.015
sensory perception GO:0007600 101 0.015
chromosome segregation GO:0007059 2 0.015
nucleotide catabolic process GO:0009166 139 0.015
cell motility GO:0048870 202 0.015
cell projection morphogenesis GO:0048858 123 0.015
regulation of transcription dna templated GO:0006355 374 0.015
response to organophosphorus GO:0046683 102 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
chemical homeostasis GO:0048878 292 0.015
Rat
positive regulation of response to stimulus GO:0048584 285 0.015
Rat
protein complex subunit organization GO:0071822 302 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of protein kinase activity GO:0045859 105 0.015
positive regulation of gene expression GO:0010628 244 0.015
response to alkaloid GO:0043279 132 0.014
cation transmembrane transport GO:0098655 263 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
ras protein signal transduction GO:0007265 29 0.014
gastrulation GO:0007369 2 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
inflammatory response GO:0006954 150 0.014
developmental process involved in reproduction GO:0003006 159 0.014
sexual reproduction GO:0019953 148 0.014
cell cycle checkpoint GO:0000075 2 0.014
muscle structure development GO:0061061 87 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
response to other organism GO:0051707 220 0.014
epithelial cell proliferation GO:0050673 54 0.014
Rat
response to growth factor GO:0070848 189 0.014
positive regulation of developmental process GO:0051094 283 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
female pregnancy GO:0007565 122 0.014
small molecule catabolic process GO:0044282 59 0.014
regulation of transferase activity GO:0051338 123 0.014
cellular response to lipid GO:0071396 201 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
gamete generation GO:0007276 124 0.013
regulation of neuron projection development GO:0010975 161 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
Rat
positive regulation of cell communication GO:0010647 271 0.013
muscle system process GO:0003012 115 0.013
response to interleukin 1 GO:0070555 55 0.013
cell migration GO:0016477 197 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular chemical homeostasis GO:0055082 247 0.013
Rat
transmission of nerve impulse GO:0019226 42 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
response to bacterium GO:0009617 200 0.013
oxidation reduction process GO:0055114 304 0.013
response to biotic stimulus GO:0009607 226 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
establishment of protein localization GO:0045184 141 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
Rat
response to axon injury GO:0048678 59 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
multicellular organismal signaling GO:0035637 44 0.013
cell part morphogenesis GO:0032990 123 0.013
regulation of cell motility GO:2000145 131 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
epithelium development GO:0060429 96 0.013
cellular ion homeostasis GO:0006873 184 0.012
developmental growth GO:0048589 100 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
cardiac ventricle development GO:0003231 1 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
axis specification GO:0009798 4 0.012
neuron projection morphogenesis GO:0048812 122 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
response to radiation GO:0009314 137 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to fatty acid GO:0070542 65 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
vesicle mediated transport GO:0016192 181 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
positive regulation of cell death GO:0010942 184 0.012
positive regulation of ion transport GO:0043270 94 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of signaling GO:0023056 270 0.012
muscle contraction GO:0006936 88 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
multicellular organism growth GO:0035264 1 0.011
eye morphogenesis GO:0048592 4 0.011
intestinal absorption GO:0050892 3 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
organic anion transport GO:0015711 132 0.011
response to lipopolysaccharide GO:0032496 191 0.011
cell growth GO:0016049 104 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
immune system process GO:0002376 204 0.011
regulation of transmembrane transport GO:0034762 122 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
Rat
cellular response to growth factor stimulus GO:0071363 162 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
urogenital system development GO:0001655 78 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
heart morphogenesis GO:0003007 3 0.011
spermatogenesis GO:0007283 99 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
hormone metabolic process GO:0042445 69 0.011
negative regulation of cell communication GO:0010648 158 0.011
anion transport GO:0006820 178 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of metal ion transport GO:0010959 118 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
dna metabolic process GO:0006259 96 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
Rat
cytoskeleton organization GO:0007010 111 0.011
reproductive system development GO:0061458 128 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
coenzyme metabolic process GO:0006732 86 0.011
appendage morphogenesis GO:0035107 4 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
signal release GO:0023061 145 0.011
dephosphorylation GO:0016311 98 0.010
positive regulation of transferase activity GO:0051347 81 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
neuronal action potential GO:0019228 35 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
carboxylic acid transport GO:0046942 115 0.010
respiratory system process GO:0003016 3 0.010
male gamete generation GO:0048232 99 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
circulatory system development GO:0072359 134 0.010
neural crest cell differentiation GO:0014033 2 0.010
salivary gland development GO:0007431 3 0.010
hormone transport GO:0009914 121 0.010
striated muscle tissue development GO:0014706 58 0.010
positive regulation of secretion GO:0051047 140 0.010
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010

Cpa2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.016
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.012