Rattus norvegicus

77 known processes

Opa1

optic atrophy 1 homolog (human)

(Aliases: MGC124921)

Opa1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism organelle organization GO:1902589 180 0.133
regulation of cellular component organization GO:0051128 368 0.117
vesicle mediated transport GO:0016192 181 0.112
single organism biosynthetic process GO:0044711 342 0.111
organelle organization GO:0006996 266 0.092
anatomical structure morphogenesis GO:0009653 298 0.072
cognition GO:0050890 92 0.071
intracellular signal transduction GO:0035556 314 0.063
response to inorganic substance GO:0010035 377 0.060
transmembrane transport GO:0055085 412 0.057
cellular response to endogenous stimulus GO:0071495 377 0.055
reproductive process GO:0022414 372 0.051
organophosphate metabolic process GO:0019637 370 0.050
regulation of catalytic activity GO:0050790 304 0.048
metal ion transport GO:0030001 289 0.048
macromolecular complex subunit organization GO:0043933 339 0.048
cellular response to stress GO:0033554 269 0.048
secretion by cell GO:0032940 248 0.046
cation transport GO:0006812 382 0.045
aging GO:0007568 241 0.044
response to extracellular stimulus GO:0009991 380 0.043
response to oxygen levels GO:0070482 265 0.043
regulation of cellular localization GO:0060341 263 0.043
secretion GO:0046903 307 0.042
homeostatic process GO:0042592 331 0.042
ion transmembrane transport GO:0034220 365 0.042
regulation of cell differentiation GO:0045595 320 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
establishment of protein localization GO:0045184 141 0.041
protein transport GO:0015031 132 0.040
protein phosphorylation GO:0006468 345 0.040
response to metal ion GO:0010038 253 0.040
carboxylic acid metabolic process GO:0019752 289 0.040
regulation of nervous system development GO:0051960 264 0.039
cellular amino acid metabolic process GO:0006520 107 0.039
cation transmembrane transport GO:0098655 263 0.039
response to growth factor GO:0070848 189 0.039
cell cell signaling GO:0007267 335 0.039
organic acid metabolic process GO:0006082 292 0.038
cellular component biogenesis GO:0044085 368 0.038
neurological system process GO:0050877 219 0.037
cellular component morphogenesis GO:0032989 155 0.036
response to nutrient levels GO:0031667 370 0.036
single organism behavior GO:0044708 130 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
rna metabolic process GO:0016070 406 0.036
single organism cellular localization GO:1902580 102 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
oxoacid metabolic process GO:0043436 290 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
transcription dna templated GO:0006351 377 0.035
cellular response to oxidative stress GO:0034599 76 0.035
response to hypoxia GO:0001666 231 0.033
mitochondrion organization GO:0007005 35 0.032
regulation of molecular function GO:0065009 398 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.031
response to cytokine GO:0034097 215 0.031
cellular component movement GO:0006928 248 0.031
central nervous system development GO:0007417 311 0.031
growth GO:0040007 165 0.030
response to decreased oxygen levels GO:0036293 237 0.030
synaptic transmission GO:0007268 235 0.030
neuron differentiation GO:0030182 368 0.030
dna metabolic process GO:0006259 96 0.030
single organism reproductive process GO:0044702 297 0.030
regulation of protein modification process GO:0031399 194 0.029
protein localization GO:0008104 191 0.029
single organism intracellular transport GO:1902582 166 0.029
nucleotide metabolic process GO:0009117 279 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
chemical homeostasis GO:0048878 292 0.028
ras protein signal transduction GO:0007265 29 0.028
positive regulation of transport GO:0051050 245 0.027
response to nutrient GO:0007584 248 0.027
brain development GO:0007420 247 0.027
multicellular organism reproduction GO:0032504 233 0.027
cellular homeostasis GO:0019725 252 0.027
response to oxidative stress GO:0006979 186 0.027
regulation of rna metabolic process GO:0051252 391 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.026
macromolecule localization GO:0033036 252 0.026
head development GO:0060322 247 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
regulation of transcription dna templated GO:0006355 374 0.025
cell migration GO:0016477 197 0.025
regulation of signal transduction GO:0009966 318 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
cell part morphogenesis GO:0032990 123 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
positive regulation of cell projection organization GO:0031346 111 0.024
rna biosynthetic process GO:0032774 380 0.024
regulation of hydrolase activity GO:0051336 143 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
response to estradiol GO:0032355 164 0.024
regulation of protein metabolic process GO:0051246 289 0.024
response to external biotic stimulus GO:0043207 221 0.024
protein complex biogenesis GO:0070271 263 0.023
endocytosis GO:0006897 84 0.023
multi organism reproductive process GO:0044703 262 0.023
cell cycle GO:0007049 101 0.023
protein complex assembly GO:0006461 263 0.023
cellular ion homeostasis GO:0006873 184 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
neuron development GO:0048666 286 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
cellular amine metabolic process GO:0044106 38 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
cytoskeleton organization GO:0007010 111 0.022
regulation of neuron projection development GO:0010975 161 0.022
cellular macromolecule localization GO:0070727 122 0.022
purine containing compound metabolic process GO:0072521 253 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
response to peptide GO:1901652 292 0.022
regulation of membrane potential GO:0042391 110 0.022
response to toxic substance GO:0009636 133 0.022
membrane organization GO:0061024 94 0.022
protein complex subunit organization GO:0071822 302 0.022
regulation of secretion by cell GO:1903530 208 0.021
response to bacterium GO:0009617 200 0.021
intracellular transport GO:0046907 185 0.021
nitrogen compound transport GO:0071705 229 0.021
lipid metabolic process GO:0006629 283 0.021
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
amine metabolic process GO:0009308 38 0.021
positive regulation of cell communication GO:0010647 271 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
positive regulation of gene expression GO:0010628 244 0.021
reproduction GO:0000003 245 0.021
cellular chemical homeostasis GO:0055082 247 0.021
catabolic process GO:0009056 351 0.021
regulation of neurogenesis GO:0050767 247 0.021
organophosphate catabolic process GO:0046434 148 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
behavior GO:0007610 205 0.021
response to estrogen GO:0043627 232 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
regulation of cell proliferation GO:0042127 359 0.020
acetyl coa metabolic process GO:0006084 17 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
regulation of secretion GO:0051046 224 0.020
response to acid chemical GO:0001101 222 0.020
negative regulation of metabolic process GO:0009892 331 0.020
regulation of cell development GO:0060284 263 0.019
regulation of growth GO:0040008 105 0.019
phospholipid metabolic process GO:0006644 61 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
cellular component assembly GO:0022607 360 0.019
translation GO:0006412 35 0.019
learning or memory GO:0007611 90 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
developmental process involved in reproduction GO:0003006 159 0.019
apoptotic process GO:0006915 381 0.019
nucleic acid templated transcription GO:0097659 379 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
cell motility GO:0048870 202 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of apoptotic process GO:0042981 335 0.019
cytoplasmic transport GO:0016482 115 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
response to peptide hormone GO:0043434 278 0.018
response to lipopolysaccharide GO:0032496 191 0.018
signal release GO:0023061 145 0.018
aromatic compound catabolic process GO:0019439 168 0.018
response to carbohydrate GO:0009743 183 0.018
cellular ketone metabolic process GO:0042180 51 0.018
negative regulation of developmental process GO:0051093 125 0.018
regulation of ion transport GO:0043269 245 0.018
locomotion GO:0040011 237 0.018
actin filament based process GO:0030029 86 0.018
positive regulation of developmental process GO:0051094 283 0.018
neuron projection development GO:0031175 273 0.018
response to glucose GO:0009749 136 0.018
localization of cell GO:0051674 202 0.018
single organism membrane organization GO:0044802 74 0.017
response to other organism GO:0051707 220 0.017
anion transport GO:0006820 178 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
positive regulation of cell development GO:0010720 176 0.017
response to biotic stimulus GO:0009607 226 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of organelle organization GO:0033043 80 0.017
response to ethanol GO:0045471 162 0.017
positive regulation of nervous system development GO:0051962 178 0.017
intracellular protein transport GO:0006886 79 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
carboxylic acid transport GO:0046942 115 0.017
positive regulation of catabolic process GO:0009896 78 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
positive regulation of secretion GO:0051047 140 0.016
regulation of programmed cell death GO:0043067 341 0.016
mesoderm development GO:0007498 2 0.016
nucleoside metabolic process GO:0009116 179 0.016
regulation of cell projection organization GO:0031344 175 0.016
carbohydrate metabolic process GO:0005975 130 0.016
regulation of phosphorylation GO:0042325 248 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
positive regulation of mitochondrion organization GO:0010822 4 0.016
response to alkaloid GO:0043279 132 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
metal ion homeostasis GO:0055065 186 0.016
gland development GO:0048732 155 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
reproductive system development GO:0061458 128 0.015
programmed cell death GO:0012501 392 0.015
regulation of anatomical structure size GO:0090066 135 0.015
cellular cation homeostasis GO:0030003 180 0.015
response to monosaccharide GO:0034284 159 0.015
cation homeostasis GO:0055080 195 0.015
negative regulation of gene expression GO:0010629 199 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
cell growth GO:0016049 104 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
cellular catabolic process GO:0044248 295 0.015
sulfur compound metabolic process GO:0006790 70 0.014
forebrain development GO:0030900 98 0.014
protein localization to organelle GO:0033365 57 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
negative regulation of molecular function GO:0044092 133 0.014
glycerolipid metabolic process GO:0046486 67 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cellular response to lipid GO:0071396 201 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
regulation of catabolic process GO:0009894 113 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
muscle system process GO:0003012 115 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
dephosphorylation GO:0016311 98 0.014
amide transport GO:0042886 105 0.013
positive regulation of signaling GO:0023056 270 0.013
cell projection organization GO:0030030 302 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
circulatory system development GO:0072359 134 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
heterocycle catabolic process GO:0046700 167 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
response to vitamin GO:0033273 131 0.013
organic anion transport GO:0015711 132 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
reproductive structure development GO:0048608 128 0.013
actin cytoskeleton organization GO:0030036 73 0.013
positive regulation of organelle organization GO:0010638 48 0.013
adult locomotory behavior GO:0008344 4 0.013
cell morphogenesis GO:0000902 142 0.013
response to hexose GO:0009746 144 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
alcohol metabolic process GO:0006066 77 0.013
divalent metal ion transport GO:0070838 132 0.013
axis specification GO:0009798 4 0.013
peptidyl amino acid modification GO:0018193 126 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
response to wounding GO:0009611 254 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
oxidation reduction process GO:0055114 304 0.012
cofactor biosynthetic process GO:0051188 28 0.012
spindle organization GO:0007051 2 0.012
positive regulation of cell death GO:0010942 184 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of protein localization GO:0032880 81 0.012
regeneration GO:0031099 163 0.012
organic substance catabolic process GO:1901575 316 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
ion homeostasis GO:0050801 212 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
divalent inorganic cation transport GO:0072511 134 0.012
regulation of locomotion GO:0040012 148 0.012
regulation of cell growth GO:0001558 85 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
transmission of nerve impulse GO:0019226 42 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cofactor metabolic process GO:0051186 95 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of system process GO:0044057 208 0.011
response to insulin GO:0032868 133 0.011
tissue development GO:0009888 252 0.011
regulation of protein kinase activity GO:0045859 105 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
nucleotide catabolic process GO:0009166 139 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
wound healing GO:0042060 122 0.011
b cell differentiation GO:0030183 2 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
organelle localization GO:0051640 55 0.011
organic acid transport GO:0015849 116 0.011
chromosome segregation GO:0007059 2 0.011
cellular response to peptide GO:1901653 133 0.011
lipid biosynthetic process GO:0008610 128 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
p38mapk cascade GO:0038066 1 0.011
anterior posterior pattern specification GO:0009952 1 0.011
multicellular organismal signaling GO:0035637 44 0.011
response to ketone GO:1901654 182 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
response to temperature stimulus GO:0009266 94 0.011
defense response GO:0006952 194 0.011
negative regulation of transport GO:0051051 136 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cellular component maintenance GO:0043954 4 0.011
embryonic pattern specification GO:0009880 1 0.011
negative regulation of signaling GO:0023057 157 0.011
sexual reproduction GO:0019953 148 0.011
positive regulation of protein modification process GO:0031401 142 0.011
response to corticosteroid GO:0031960 235 0.011
multi multicellular organism process GO:0044706 138 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of mapk cascade GO:0043408 116 0.011
gastrulation GO:0007369 2 0.011
spermatogenesis GO:0007283 99 0.011
immune response GO:0006955 104 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
centrosome cycle GO:0007098 1 0.011
regulation of vesicle mediated transport GO:0060627 81 0.010
calcium ion transport GO:0006816 131 0.010
regulation of cellular component movement GO:0051270 150 0.010
regulation of response to external stimulus GO:0032101 106 0.010
positive regulation of lipid catabolic process GO:0050996 4 0.010
negative regulation of cell communication GO:0010648 158 0.010
interleukin 12 production GO:0032615 3 0.010
neuron death GO:0070997 127 0.010
neuromuscular process GO:0050905 2 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
nucleoside catabolic process GO:0009164 126 0.010
neuron projection morphogenesis GO:0048812 122 0.010
rho protein signal transduction GO:0007266 11 0.010
male gamete generation GO:0048232 99 0.010
proteolysis GO:0006508 175 0.010

Opa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.013