Rattus norvegicus

0 known processes

Cfl2

cofilin 2, muscle

Cfl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.116
rna biosynthetic process GO:0032774 380 0.088
oxoacid metabolic process GO:0043436 290 0.084
nucleobase biosynthetic process GO:0046112 2 0.082
negative regulation of metabolic process GO:0009892 331 0.071
regulation of cellular component organization GO:0051128 368 0.069
cell projection organization GO:0030030 302 0.067
carboxylic acid metabolic process GO:0019752 289 0.058
protein complex subunit organization GO:0071822 302 0.057
single organism biosynthetic process GO:0044711 342 0.053
intracellular transport GO:0046907 185 0.052
negative regulation of signaling GO:0023057 157 0.052
negative regulation of response to stimulus GO:0048585 155 0.051
regulation of neuron projection development GO:0010975 161 0.051
regulation of rna biosynthetic process GO:2001141 381 0.048
amine metabolic process GO:0009308 38 0.045
programmed cell death GO:0012501 392 0.045
transcription dna templated GO:0006351 377 0.044
regulation of cell projection organization GO:0031344 175 0.044
regulation of programmed cell death GO:0043067 341 0.043
response to nutrient levels GO:0031667 370 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
regulation of cell differentiation GO:0045595 320 0.040
macromolecular complex assembly GO:0065003 273 0.040
negative regulation of cell communication GO:0010648 158 0.040
response to extracellular stimulus GO:0009991 380 0.039
protein modification by small protein conjugation GO:0032446 31 0.038
single organism intracellular transport GO:1902582 166 0.036
protein complex assembly GO:0006461 263 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
positive regulation of cellular amine metabolic process GO:0033240 3 0.034
regulation of cell development GO:0060284 263 0.033
nucleic acid templated transcription GO:0097659 379 0.033
response to hypoxia GO:0001666 231 0.031
protein modification by small protein conjugation or removal GO:0070647 35 0.031
cellular amine metabolic process GO:0044106 38 0.031
regulation of rna metabolic process GO:0051252 391 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.030
central nervous system development GO:0007417 311 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
negative regulation of cell death GO:0060548 229 0.028
response to ethanol GO:0045471 162 0.028
cellular amino acid metabolic process GO:0006520 107 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of apoptotic process GO:0042981 335 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
catabolic process GO:0009056 351 0.025
neuron development GO:0048666 286 0.025
cellular protein localization GO:0034613 122 0.025
regulation of neurogenesis GO:0050767 247 0.025
negative regulation of signal transduction GO:0009968 83 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
response to oxygen levels GO:0070482 265 0.024
establishment of protein localization GO:0045184 141 0.023
regulation of phosphorylation GO:0042325 248 0.023
neuron differentiation GO:0030182 368 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
negative regulation of cellular component organization GO:0051129 83 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
glucan metabolic process GO:0044042 23 0.022
cellular response to stress GO:0033554 269 0.022
response to wounding GO:0009611 254 0.021
regulation of neuron differentiation GO:0045664 208 0.021
rna metabolic process GO:0016070 406 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
regulation of system process GO:0044057 208 0.020
head development GO:0060322 247 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
organophosphate metabolic process GO:0019637 370 0.019
neuron projection development GO:0031175 273 0.019
secretion by cell GO:0032940 248 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
protein complex biogenesis GO:0070271 263 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
protein oligomerization GO:0051259 191 0.019
regulation of nervous system development GO:0051960 264 0.019
plasma lipoprotein particle clearance GO:0034381 3 0.019
cellular macromolecule localization GO:0070727 122 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.018
apoptotic process GO:0006915 381 0.018
response to nutrient GO:0007584 248 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
organelle organization GO:0006996 266 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
negative regulation of gene expression GO:0010629 199 0.018
organic substance catabolic process GO:1901575 316 0.017
protein import GO:0017038 37 0.017
response to peptide hormone GO:0043434 278 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
regulation of molecular function GO:0065009 398 0.017
cytoplasmic transport GO:0016482 115 0.017
ion transmembrane transport GO:0034220 365 0.017
regulation of cellular component biogenesis GO:0044087 86 0.016
response to carbohydrate GO:0009743 183 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
regulation of cell growth GO:0001558 85 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
transmembrane transport GO:0055085 412 0.016
heart development GO:0007507 72 0.016
cellular catabolic process GO:0044248 295 0.016
response to external biotic stimulus GO:0043207 221 0.016
regulation of transcription dna templated GO:0006355 374 0.016
nucleotide metabolic process GO:0009117 279 0.016
regulation of protein metabolic process GO:0051246 289 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
cellular polysaccharide metabolic process GO:0044264 23 0.016
regulation of plasma lipoprotein particle levels GO:0097006 3 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
regulation of anatomical structure size GO:0090066 135 0.015
response to other organism GO:0051707 220 0.015
ribonucleoside metabolic process GO:0009119 174 0.014
pseudopodium organization GO:0031268 3 0.014
protein localization GO:0008104 191 0.014
response to decreased oxygen levels GO:0036293 237 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
single organism catabolic process GO:0044712 283 0.014
cell motility GO:0048870 202 0.014
regulation of cellular localization GO:0060341 263 0.014
cellular ketone metabolic process GO:0042180 51 0.014
positive regulation of transport GO:0051050 245 0.014
cellular homeostasis GO:0019725 252 0.014
macromolecule catabolic process GO:0009057 58 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
cellular component biogenesis GO:0044085 368 0.013
gamete generation GO:0007276 124 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
spermatogenesis GO:0007283 99 0.013
sulfur compound metabolic process GO:0006790 70 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
response to inorganic substance GO:0010035 377 0.013
muscle system process GO:0003012 115 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
fatty acid metabolic process GO:0006631 99 0.013
cellular response to external stimulus GO:0071496 118 0.013
localization of cell GO:0051674 202 0.013
protein phosphorylation GO:0006468 345 0.012
synaptic transmission GO:0007268 235 0.012
positive regulation of nervous system development GO:0051962 178 0.012
macromolecule localization GO:0033036 252 0.012
response to lipopolysaccharide GO:0032496 191 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
regulation of blood circulation GO:1903522 110 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cell cell signaling GO:0007267 335 0.012
multicellular organism reproduction GO:0032504 233 0.012
organ formation GO:0048645 3 0.012
positive regulation of developmental process GO:0051094 283 0.012
response to vitamin GO:0033273 131 0.012
defense response GO:0006952 194 0.012
cellular response to lipid GO:0071396 201 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
vesicle mediated transport GO:0016192 181 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
nitrogen compound transport GO:0071705 229 0.012
multicellular organismal reproductive process GO:0048609 233 0.011
locomotion GO:0040011 237 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
circulatory system development GO:0072359 134 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
pigment biosynthetic process GO:0046148 4 0.011
cofactor biosynthetic process GO:0051188 28 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
negative regulation of epithelial cell proliferation GO:0050680 16 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
purine nucleobase metabolic process GO:0006144 4 0.011
regulation of membrane potential GO:0042391 110 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
positive regulation of cell development GO:0010720 176 0.010
muscle cell proliferation GO:0033002 84 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
multi organism reproductive process GO:0044703 262 0.010
male gamete generation GO:0048232 99 0.010

Cfl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050
sensory system disease DOID:0050155 0 0.043
eye and adnexa disease DOID:1492 0 0.043
eye disease DOID:5614 0 0.043
musculoskeletal system disease DOID:17 0 0.029
retinal disease DOID:5679 0 0.022
retinal degeneration DOID:8466 0 0.022
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.013
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011