Rattus norvegicus

0 known processes

Steap4

STEAP family member 4

Steap4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to other organism GO:0051707 220 0.144
cellular response to oxygen containing compound GO:1901701 386 0.117
response to external biotic stimulus GO:0043207 221 0.115
cellular response to lipid GO:0071396 201 0.114
response to biotic stimulus GO:0009607 226 0.108
regulation of cell proliferation GO:0042127 359 0.100
response to bacterium GO:0009617 200 0.086
regulation of rna biosynthetic process GO:2001141 381 0.084
regulation of rna metabolic process GO:0051252 391 0.082
response to molecule of bacterial origin GO:0002237 194 0.080
regulation of nucleic acid templated transcription GO:1903506 380 0.076
programmed cell death GO:0012501 392 0.074
regulation of cellular ketone metabolic process GO:0010565 27 0.072
positive regulation of cell proliferation GO:0008284 249 0.071
rna metabolic process GO:0016070 406 0.069
positive regulation of response to stimulus GO:0048584 285 0.065
rna biosynthetic process GO:0032774 380 0.063
transcription dna templated GO:0006351 377 0.062
response to metal ion GO:0010038 253 0.062
regulation of molecular function GO:0065009 398 0.061
regulation of transcription dna templated GO:0006355 374 0.059
protein phosphorylation GO:0006468 345 0.058
response to cytokine GO:0034097 215 0.052
carboxylic acid metabolic process GO:0019752 289 0.052
organic acid metabolic process GO:0006082 292 0.051
cellular ketone metabolic process GO:0042180 51 0.050
response to lipopolysaccharide GO:0032496 191 0.049
regulation of protein metabolic process GO:0051246 289 0.048
response to extracellular stimulus GO:0009991 380 0.048
response to nutrient GO:0007584 248 0.046
positive regulation of signaling GO:0023056 270 0.046
regulation of protein phosphorylation GO:0001932 183 0.045
multi multicellular organism process GO:0044706 138 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.045
regulation of programmed cell death GO:0043067 341 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.044
aging GO:0007568 241 0.044
locomotion GO:0040011 237 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
transmembrane transport GO:0055085 412 0.041
cellular response to stress GO:0033554 269 0.041
oxoacid metabolic process GO:0043436 290 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
positive regulation of cell death GO:0010942 184 0.041
response to inorganic substance GO:0010035 377 0.041
response to nutrient levels GO:0031667 370 0.041
response to peptide GO:1901652 292 0.041
regulation of apoptotic process GO:0042981 335 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.040
cellular response to molecule of bacterial origin GO:0071219 56 0.040
reproductive process GO:0022414 372 0.039
metal ion transport GO:0030001 289 0.038
Mouse
defense response GO:0006952 194 0.038
nucleic acid templated transcription GO:0097659 379 0.038
apoptotic process GO:0006915 381 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
macromolecule localization GO:0033036 252 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
positive regulation of cell communication GO:0010647 271 0.036
negative regulation of metabolic process GO:0009892 331 0.036
urogenital system development GO:0001655 78 0.035
positive regulation of programmed cell death GO:0043068 157 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
cellular response to lipopolysaccharide GO:0071222 55 0.035
positive regulation of developmental process GO:0051094 283 0.035
ion transmembrane transport GO:0034220 365 0.035
cellular component biogenesis GO:0044085 368 0.034
intracellular signal transduction GO:0035556 314 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
localization of cell GO:0051674 202 0.034
regulation of catalytic activity GO:0050790 304 0.034
inflammatory response GO:0006954 150 0.034
positive regulation of rna biosynthetic process GO:1902680 197 0.034
cation transport GO:0006812 382 0.033
Mouse
synaptic transmission GO:0007268 235 0.033
positive regulation of molecular function GO:0044093 230 0.033
immune system process GO:0002376 204 0.033
cellular response to cytokine stimulus GO:0071345 127 0.033
purine containing compound metabolic process GO:0072521 253 0.033
regulation of cellular component organization GO:0051128 368 0.032
cellular response to biotic stimulus GO:0071216 59 0.032
cellular amine metabolic process GO:0044106 38 0.032
regulation of locomotion GO:0040012 148 0.032
single organism biosynthetic process GO:0044711 342 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.031
negative regulation of cell proliferation GO:0008285 119 0.031
homeostatic process GO:0042592 331 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
response to transition metal nanoparticle GO:1990267 122 0.031
cellular response to organic cyclic compound GO:0071407 202 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
cellular component movement GO:0006928 248 0.031
single organism reproductive process GO:0044702 297 0.030
chemical homeostasis GO:0048878 292 0.030
multi organism reproductive process GO:0044703 262 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
regulation of immune system process GO:0002682 123 0.029
cation homeostasis GO:0055080 195 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
protein complex assembly GO:0006461 263 0.029
positive regulation of transcription dna templated GO:0045893 197 0.029
cellular homeostasis GO:0019725 252 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
reproduction GO:0000003 245 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.028
regulation of cell differentiation GO:0045595 320 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
leukocyte activation GO:0045321 76 0.028
amine metabolic process GO:0009308 38 0.028
positive regulation of gene expression GO:0010628 244 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
lipid metabolic process GO:0006629 283 0.027
response to mechanical stimulus GO:0009612 134 0.027
female pregnancy GO:0007565 122 0.027
cell migration GO:0016477 197 0.027
cellular component assembly GO:0022607 360 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
central nervous system development GO:0007417 311 0.026
response to corticosteroid GO:0031960 235 0.026
regulation of protein modification process GO:0031399 194 0.026
positive regulation of signal transduction GO:0009967 175 0.026
negative regulation of gene expression GO:0010629 199 0.026
response to wounding GO:0009611 254 0.026
nitrogen compound transport GO:0071705 229 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
mapk cascade GO:0000165 140 0.025
protein complex subunit organization GO:0071822 302 0.025
negative regulation of transport GO:0051051 136 0.025
nucleotide metabolic process GO:0009117 279 0.025
positive regulation of transport GO:0051050 245 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
response to decreased oxygen levels GO:0036293 237 0.024
regulation of body fluid levels GO:0050878 90 0.024
response to estrogen GO:0043627 232 0.024
organic substance catabolic process GO:1901575 316 0.024
smooth muscle cell proliferation GO:0048659 77 0.024
muscle cell proliferation GO:0033002 84 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
catabolic process GO:0009056 351 0.023
protein oligomerization GO:0051259 191 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
organelle organization GO:0006996 266 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
response to ketone GO:1901654 182 0.023
cell cell signaling GO:0007267 335 0.023
regulation of response to stress GO:0080134 126 0.023
monocarboxylic acid metabolic process GO:0032787 152 0.022
negative regulation of molecular function GO:0044092 133 0.022
fatty acid metabolic process GO:0006631 99 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
neuron projection development GO:0031175 273 0.022
regeneration GO:0031099 163 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
lipid biosynthetic process GO:0008610 128 0.021
response to peptide hormone GO:0043434 278 0.021
response to vitamin GO:0033273 131 0.021
neurological system process GO:0050877 219 0.021
small molecule biosynthetic process GO:0044283 124 0.021
immune response GO:0006955 104 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of phosphorylation GO:0042325 248 0.020
cellular response to reactive oxygen species GO:0034614 55 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
reproductive system development GO:0061458 128 0.020
ion homeostasis GO:0050801 212 0.020
cytokine mediated signaling pathway GO:0019221 43 0.020
single organism organelle organization GO:1902589 180 0.020
multicellular organism reproduction GO:0032504 233 0.020
monocarboxylic acid biosynthetic process GO:0072330 48 0.020
gland development GO:0048732 155 0.019
response to insulin GO:0032868 133 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
organic acid biosynthetic process GO:0016053 83 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
metal ion homeostasis GO:0055065 186 0.019
positive regulation of cell development GO:0010720 176 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
response to glucocorticoid GO:0051384 223 0.019
response to oxygen levels GO:0070482 265 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
lipid transport GO:0006869 61 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
response to hypoxia GO:0001666 231 0.019
muscle contraction GO:0006936 88 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
cation transmembrane transport GO:0098655 263 0.019
lipid storage GO:0019915 1 0.018
regulation of membrane potential GO:0042391 110 0.018
organophosphate metabolic process GO:0019637 370 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
cellular lipid metabolic process GO:0044255 208 0.018
regulation of establishment of planar polarity GO:0090175 2 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
regulation of system process GO:0044057 208 0.018
negative regulation of signaling GO:0023057 157 0.018
negative regulation of cell death GO:0060548 229 0.018
fatty acid derivative metabolic process GO:1901568 38 0.018
response to estradiol GO:0032355 164 0.018
cellular response to oxidative stress GO:0034599 76 0.018
response to growth factor GO:0070848 189 0.018
regulation of lipid metabolic process GO:0019216 68 0.018
brain development GO:0007420 247 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
organophosphate catabolic process GO:0046434 148 0.017
rhythmic process GO:0048511 156 0.017
negative regulation of cell communication GO:0010648 158 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
regulation of lipid biosynthetic process GO:0046890 38 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cell projection organization GO:0030030 302 0.017
regulation of cell motility GO:2000145 131 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
heterocycle catabolic process GO:0046700 167 0.017
head development GO:0060322 247 0.017
regulation of mapk cascade GO:0043408 116 0.017
secretion GO:0046903 307 0.017
regulation of catabolic process GO:0009894 113 0.017
organ regeneration GO:0031100 101 0.017
regulation of ion transport GO:0043269 245 0.017
activation of immune response GO:0002253 26 0.017
regulation of response to external stimulus GO:0032101 106 0.017
cellular chemical homeostasis GO:0055082 247 0.017
positive regulation of cell motility GO:2000147 97 0.017
purine nucleoside catabolic process GO:0006152 124 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
regulation of signal transduction GO:0009966 318 0.016
protein complex biogenesis GO:0070271 263 0.016
positive regulation of immune system process GO:0002684 90 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of cellular localization GO:0060341 263 0.016
circulatory system development GO:0072359 134 0.016
muscle system process GO:0003012 115 0.016
response to carbohydrate GO:0009743 183 0.016
cellular response to insulin stimulus GO:0032869 81 0.016
positive regulation of blood circulation GO:1903524 65 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
stress activated protein kinase signaling cascade GO:0031098 37 0.016
cellular cation homeostasis GO:0030003 180 0.016
positive regulation of secretion GO:0051047 140 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
regulation of cellular component movement GO:0051270 150 0.015
interleukin 6 production GO:0032635 12 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
purine containing compound catabolic process GO:0072523 138 0.015
neuron differentiation GO:0030182 368 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
nucleoside metabolic process GO:0009116 179 0.015
response to toxic substance GO:0009636 133 0.015
lipid localization GO:0010876 62 0.015
cell motility GO:0048870 202 0.015
defense response to gram positive bacterium GO:0050830 2 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
glial cell differentiation GO:0010001 65 0.015
regulation of neurogenesis GO:0050767 247 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
cellular response to peptide GO:1901653 133 0.015
cardiovascular system development GO:0072358 134 0.015
neuron development GO:0048666 286 0.015
cognition GO:0050890 92 0.015
response to acid chemical GO:0001101 222 0.015
cellular ion homeostasis GO:0006873 184 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
sexual reproduction GO:0019953 148 0.014
regulation of hormone levels GO:0010817 187 0.014
positive regulation of cell migration GO:0030335 96 0.014
neuronal action potential GO:0019228 35 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
single organism catabolic process GO:0044712 283 0.014
response to monosaccharide GO:0034284 159 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
regulation of secretion GO:0051046 224 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
response to temperature stimulus GO:0009266 94 0.014
dna metabolic process GO:0006259 96 0.014
peptidyl amino acid modification GO:0018193 126 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of secretion by cell GO:1903530 208 0.013
macromolecular complex assembly GO:0065003 273 0.013
cellular macromolecule localization GO:0070727 122 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
action potential GO:0001508 54 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
maintenance of location GO:0051235 17 0.013
regulation of nervous system development GO:0051960 264 0.013
response to oxidative stress GO:0006979 186 0.013
proteolysis GO:0006508 175 0.013
regulation of ossification GO:0030278 32 0.013
cellular protein localization GO:0034613 122 0.013
vesicle mediated transport GO:0016192 181 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
muscle cell differentiation GO:0042692 52 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
aromatic compound catabolic process GO:0019439 168 0.013
anterior posterior pattern specification GO:0009952 1 0.013
developmental process involved in reproduction GO:0003006 159 0.013
gamete generation GO:0007276 124 0.013
establishment of protein localization GO:0045184 141 0.012
eye morphogenesis GO:0048592 4 0.012
bmp signaling pathway GO:0030509 4 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
blood circulation GO:0008015 183 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of kinase activity GO:0043549 117 0.012
positive regulation of ion transport GO:0043270 94 0.012
jak stat cascade GO:0007259 26 0.012
response to fatty acid GO:0070542 65 0.012
positive regulation of locomotion GO:0040017 102 0.012
sensory perception of pain GO:0019233 73 0.012
regulation of transmembrane transport GO:0034762 122 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
ras protein signal transduction GO:0007265 29 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
cell activation GO:0001775 97 0.012
cytokine production GO:0001816 61 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
regulation of blood circulation GO:1903522 110 0.012
positive regulation of immune response GO:0050778 42 0.012
renal system development GO:0072001 67 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.012
programmed necrotic cell death GO:0097300 2 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
calcium ion homeostasis GO:0055074 162 0.012
protein transport GO:0015031 132 0.012
gliogenesis GO:0042063 93 0.012
regulation of synaptic transmission GO:0050804 141 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
anion transport GO:0006820 178 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
nucleoside catabolic process GO:0009164 126 0.012
cellular response to alcohol GO:0097306 87 0.012
regulation of cell migration GO:0030334 128 0.011
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
regulation of cell development GO:0060284 263 0.011
regulation of peptide transport GO:0090087 87 0.011
regulation of interleukin 6 production GO:0032675 12 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of dna metabolic process GO:0051052 60 0.011
nuclear transport GO:0051169 49 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
regulation of growth GO:0040008 105 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
secretion by cell GO:0032940 248 0.011
cellular response to external stimulus GO:0071496 118 0.011
cellular response to ketone GO:1901655 51 0.011
response to hexose GO:0009746 144 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of protein modification process GO:0031401 142 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
ossification GO:0001503 70 0.011
learning or memory GO:0007611 90 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
fatty acid biosynthetic process GO:0006633 33 0.011
cytokine biosynthetic process GO:0042089 3 0.011
cell type specific apoptotic process GO:0097285 134 0.011
vasculature development GO:0001944 70 0.011
regulation of cell activation GO:0050865 50 0.011
negative regulation of viral process GO:0048525 4 0.011
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
response to alkaloid GO:0043279 132 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
regulation of muscle system process GO:0090257 79 0.010
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
response to interleukin 1 GO:0070555 55 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
protein homooligomerization GO:0051260 91 0.010
kidney development GO:0001822 67 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
activation of cysteine type endopeptidase activity GO:0097202 4 0.010
cellular response to corticosteroid stimulus GO:0071384 69 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
potassium ion transport GO:0006813 97 0.010
antigen processing and presentation GO:0019882 2 0.010
rho protein signal transduction GO:0007266 11 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
taxis GO:0042330 67 0.010
salivary gland development GO:0007431 3 0.010
tissue development GO:0009888 252 0.010
hormone transport GO:0009914 121 0.010
acid secretion GO:0046717 48 0.010
negative regulation of developmental process GO:0051093 125 0.010
negative regulation of protein modification process GO:0031400 52 0.010
sensory perception GO:0007600 101 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
single organism intracellular transport GO:1902582 166 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
axis specification GO:0009798 4 0.010

Steap4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.011
disease of cellular proliferation DOID:14566 0 0.010