Rattus norvegicus

0 known processes

Npc2

Niemann-Pick disease, type C2

(Aliases: re1)

Npc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 152 0.089
synaptic transmission GO:0007268 235 0.079
multi organism reproductive process GO:0044703 262 0.060
response to estrogen GO:0043627 232 0.055
response to inorganic substance GO:0010035 377 0.048
cation transmembrane transport GO:0098655 263 0.047
response to glucocorticoid GO:0051384 223 0.045
gamete generation GO:0007276 124 0.038
cell migration GO:0016477 197 0.037
sexual reproduction GO:0019953 148 0.035
organic substance catabolic process GO:1901575 316 0.034
catabolic process GO:0009056 351 0.034
programmed cell death GO:0012501 392 0.033
reproductive process GO:0022414 372 0.033
defense response GO:0006952 194 0.033
response to corticosteroid GO:0031960 235 0.033
cellular response to stress GO:0033554 269 0.032
regulation of programmed cell death GO:0043067 341 0.031
positive regulation of apoptotic process GO:0043065 154 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
organic acid biosynthetic process GO:0016053 83 0.029
peptide metabolic process GO:0006518 32 0.028
proteolysis GO:0006508 175 0.028
cellular catabolic process GO:0044248 295 0.028
multicellular organism reproduction GO:0032504 233 0.027
response to other organism GO:0051707 220 0.025
regulation of apoptotic process GO:0042981 335 0.024
positive regulation of developmental process GO:0051094 283 0.023
lipid metabolic process GO:0006629 283 0.022
regulation of cell differentiation GO:0045595 320 0.022
response to biotic stimulus GO:0009607 226 0.021
neuron projection development GO:0031175 273 0.021
ion transmembrane transport GO:0034220 365 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
cellular amide metabolic process GO:0043603 44 0.021
regulation of body fluid levels GO:0050878 90 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
immune system process GO:0002376 204 0.020
regulation of neurogenesis GO:0050767 247 0.020
regeneration GO:0031099 163 0.019
amino sugar metabolic process GO:0006040 12 0.019
cellular lipid metabolic process GO:0044255 208 0.018
secretion GO:0046903 307 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
single organism reproductive process GO:0044702 297 0.017
cellular response to vascular endothelial growth factor stimulus GO:0035924 6 0.017
positive regulation of signaling GO:0023056 270 0.017
response to vitamin GO:0033273 131 0.017
tissue development GO:0009888 252 0.017
negative regulation of developmental process GO:0051093 125 0.017
lipid biosynthetic process GO:0008610 128 0.017
response to peptide GO:1901652 292 0.017
wound healing GO:0042060 122 0.017
response to estradiol GO:0032355 164 0.017
metal ion transport GO:0030001 289 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of molecular function GO:0065009 398 0.016
regulation of ion transport GO:0043269 245 0.015
regulation of cell development GO:0060284 263 0.015
response to acid chemical GO:0001101 222 0.015
response to radiation GO:0009314 137 0.015
macromolecule catabolic process GO:0009057 58 0.015
lymphocyte activation GO:0046649 43 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
response to oxygen levels GO:0070482 265 0.014
cellular component movement GO:0006928 248 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
spermatogenesis GO:0007283 99 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
cell motility GO:0048870 202 0.013
respiratory system development GO:0060541 45 0.013
response to metal ion GO:0010038 253 0.013
apoptotic process GO:0006915 381 0.013
circulatory system process GO:0003013 183 0.013
response to nutrient levels GO:0031667 370 0.013
positive regulation of dendritic spine development GO:0060999 9 0.013
amine metabolic process GO:0009308 38 0.013
chemical homeostasis GO:0048878 292 0.013
cell cell signaling GO:0007267 335 0.013
response to extracellular stimulus GO:0009991 380 0.013
reproduction GO:0000003 245 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
single organism catabolic process GO:0044712 283 0.012
male gamete generation GO:0048232 99 0.011
response to amine GO:0014075 46 0.011
protein phosphorylation GO:0006468 345 0.011
multicellular organism growth GO:0035264 1 0.011
bradykinin catabolic process GO:0010815 2 0.011
regulation of cellular component organization GO:0051128 368 0.011
protein catabolic process GO:0030163 30 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
ion homeostasis GO:0050801 212 0.011
organic acid metabolic process GO:0006082 292 0.011
tissue regeneration GO:0042246 36 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
fatty acid derivative biosynthetic process GO:1901570 18 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
locomotion GO:0040011 237 0.011
response to carbohydrate GO:0009743 183 0.011
response to cytokine GO:0034097 215 0.011
reproductive structure development GO:0048608 128 0.010
regulation of metal ion transport GO:0010959 118 0.010
head development GO:0060322 247 0.010
regulation of cell motility GO:2000145 131 0.010
homeostatic process GO:0042592 331 0.010
circulatory system development GO:0072359 134 0.010
response to decreased oxygen levels GO:0036293 237 0.010
response to monosaccharide GO:0034284 159 0.010
response to reactive oxygen species GO:0000302 120 0.010
response to ethanol GO:0045471 162 0.010

Npc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.184
lysosomal storage disease DOID:3211 0 0.184
inherited metabolic disorder DOID:655 0 0.184
lipid storage disease DOID:9455 0 0.083
cerebral degeneration DOID:1443 0 0.068
central nervous system disease DOID:331 0 0.068
brain disease DOID:936 0 0.068
disease of anatomical entity DOID:7 0 0.068
nervous system disease DOID:863 0 0.068
retinal disease DOID:5679 0 0.017
retinal degeneration DOID:8466 0 0.017
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017