Rattus norvegicus

0 known processes

Klra22

killer cell lectin-like receptor subfamily A, member 22

(Aliases: Ly49,Ly49s2,Klra1)

Klra22 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.147
Rat
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.130
Rat
negative regulation of chronic inflammatory response GO:0002677 2 0.127
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.108
Rat
cellular component biogenesis GO:0044085 368 0.103
protein heterooligomerization GO:0051291 89 0.100
response to biotic stimulus GO:0009607 226 0.092
Rat
synaptic transmission GO:0007268 235 0.089
cellular amine metabolic process GO:0044106 38 0.086
protein transport GO:0015031 132 0.074
monovalent inorganic cation transport GO:0015672 172 0.072
response to inorganic substance GO:0010035 377 0.064
Rat
cation transport GO:0006812 382 0.062
immune system process GO:0002376 204 0.061
Rat
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.060
Rat
response to external biotic stimulus GO:0043207 221 0.058
inorganic cation transmembrane transport GO:0098662 202 0.057
cellular metal ion homeostasis GO:0006875 172 0.055
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.055
Rat
amine metabolic process GO:0009308 38 0.053
cognition GO:0050890 92 0.053
negative regulation of response to tumor cell GO:0002835 2 0.050
Rat
cellular component assembly GO:0022607 360 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.049
head development GO:0060322 247 0.048
leukocyte activation GO:0045321 76 0.048
Rat
organophosphate metabolic process GO:0019637 370 0.045
cellular amino acid metabolic process GO:0006520 107 0.045
negative regulation of innate immune response GO:0045824 4 0.045
Rat
male mating behavior GO:0060179 3 0.045
negative regulation of long term synaptic potentiation GO:1900272 1 0.044
response to bacterium GO:0009617 200 0.043
small molecule catabolic process GO:0044282 59 0.042
response to cocaine GO:0042220 39 0.042
brain development GO:0007420 247 0.042
protein phosphorylation GO:0006468 345 0.041
regulation of membrane potential GO:0042391 110 0.040
rna metabolic process GO:0016070 406 0.039
learning or memory GO:0007611 90 0.039
metal ion transport GO:0030001 289 0.038
cellular ion homeostasis GO:0006873 184 0.037
response to amine GO:0014075 46 0.036
regulation of rna biosynthetic process GO:2001141 381 0.036
protein complex subunit organization GO:0071822 302 0.036
response to amphetamine GO:0001975 25 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
protein localization GO:0008104 191 0.035
sodium ion transport GO:0006814 82 0.035
immune response GO:0006955 104 0.035
Rat
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.034
Rat
central nervous system development GO:0007417 311 0.033
neuron neuron synaptic transmission GO:0007270 60 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
regulation of signal transduction GO:0009966 318 0.032
response to radiation GO:0009314 137 0.032
angioblast cell migration GO:0035476 1 0.032
defense response GO:0006952 194 0.032
Rat
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
positive regulation of developmental process GO:0051094 283 0.031
regulation of synaptic transmission GO:0050804 141 0.031
negative regulation of immune system process GO:0002683 39 0.030
Rat
positive regulation of neurogenesis GO:0050769 165 0.030
eosinophil migration GO:0072677 3 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.030
blood vessel development GO:0001568 69 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
protein oligomerization GO:0051259 191 0.029
nucleic acid templated transcription GO:0097659 379 0.029
metanephric tubule morphogenesis GO:0072173 2 0.028
single organism catabolic process GO:0044712 283 0.028
regulation of catabolic process GO:0009894 113 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
neurological system process GO:0050877 219 0.028
regulation of system process GO:0044057 208 0.027
nitrogen compound transport GO:0071705 229 0.027
aromatic compound catabolic process GO:0019439 168 0.027
organic cyclic compound catabolic process GO:1901361 175 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.026
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
neutrophil apoptotic process GO:0001781 4 0.026
regulation of metal ion transport GO:0010959 118 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
lymphocyte chemotaxis GO:0048247 3 0.025
macromolecular complex assembly GO:0065003 273 0.025
organic hydroxy compound transport GO:0015850 77 0.024
secretion by cell GO:0032940 248 0.024
behavior GO:0007610 205 0.024
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
organelle organization GO:0006996 266 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
response to tumor cell GO:0002347 4 0.023
Rat
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.023
negative regulation of metabolic process GO:0009892 331 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
cellular ketone metabolic process GO:0042180 51 0.023
regulation of immune response GO:0050776 55 0.023
Rat
regulation of cellular localization GO:0060341 263 0.022
positive regulation of transport GO:0051050 245 0.022
cellular catabolic process GO:0044248 295 0.022
ion homeostasis GO:0050801 212 0.022
transcription dna templated GO:0006351 377 0.022
regulation of neuronal synaptic plasticity GO:0048168 31 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
t cell chemotaxis GO:0010818 2 0.022
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.022
Rat
regulation of immune system process GO:0002682 123 0.022
Rat
catabolic process GO:0009056 351 0.021
regulation of kinase activity GO:0043549 117 0.021
negative regulation of neutrophil apoptotic process GO:0033030 3 0.020
heart process GO:0003015 57 0.020
regulation of cellular component movement GO:0051270 150 0.019
regulation of catalytic activity GO:0050790 304 0.019
regulation of defense response GO:0031347 68 0.019
Rat
purine nucleotide metabolic process GO:0006163 229 0.019
regulation of molecular function GO:0065009 398 0.019
negative regulation of molecular function GO:0044092 133 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
protein complex assembly GO:0006461 263 0.018
sensory perception of pain GO:0019233 73 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
phospholipid metabolic process GO:0006644 61 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
response to ammonium ion GO:0060359 71 0.018
peptide hormone secretion GO:0030072 84 0.018
mast cell chemotaxis GO:0002551 4 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
phosphatidylinositol dephosphorylation GO:0046856 4 0.017
oxoacid metabolic process GO:0043436 290 0.017
regulation of vasculature development GO:1901342 44 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
transmembrane transport GO:0055085 412 0.017
sodium ion transmembrane transport GO:0035725 67 0.017
regulation of neutrophil apoptotic process GO:0033029 4 0.017
establishment of protein localization GO:0045184 141 0.017
negative regulation of immune response to tumor cell GO:0002838 2 0.017
Rat
regulation of long term synaptic potentiation GO:1900271 5 0.017
circulatory system development GO:0072359 134 0.017
establishment of vesicle localization GO:0051650 31 0.017
circadian rhythm GO:0007623 88 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
positive regulation of cell activation GO:0050867 34 0.016
tissue remodeling GO:0048771 40 0.016
positive regulation of cell development GO:0010720 176 0.016
cell cell signaling GO:0007267 335 0.016
regulation of t cell activation GO:0050863 23 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of cell differentiation GO:0045595 320 0.016
organic acid metabolic process GO:0006082 292 0.016
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
membrane depolarization GO:0051899 32 0.016
regulation of nervous system development GO:0051960 264 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
negative regulation of catalytic activity GO:0043086 103 0.016
homeostatic process GO:0042592 331 0.016
regulation of peptide secretion GO:0002791 82 0.016
learning GO:0007612 33 0.016
carboxylic acid metabolic process GO:0019752 289 0.015
regulation of immune response to tumor cell GO:0002837 3 0.015
Rat
intracellular signal transduction GO:0035556 314 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
response to hypoxia GO:0001666 231 0.015
transmission of nerve impulse GO:0019226 42 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
regulation of postsynaptic membrane potential GO:0060078 25 0.015
telencephalon development GO:0021537 62 0.015
signal release GO:0023061 145 0.015
regulation of secretion by cell GO:1903530 208 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
cardiovascular system development GO:0072358 134 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
leukocyte cell cell adhesion GO:0007159 4 0.014
Rat
neuronal action potential GO:0019228 35 0.014
response to starvation GO:0042594 59 0.014
positive regulation of immune system process GO:0002684 90 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
mast cell migration GO:0097531 4 0.014
nucleotide metabolic process GO:0009117 279 0.014
regulation of protein metabolic process GO:0051246 289 0.014
response to toxic substance GO:0009636 133 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
regulation of protein modification process GO:0031399 194 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
single organism behavior GO:0044708 130 0.014
muscle system process GO:0003012 115 0.014
protein complex biogenesis GO:0070271 263 0.013
synaptic transmission glutamatergic GO:0035249 33 0.013
tumor necrosis factor biosynthetic process GO:0042533 1 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
rna biosynthetic process GO:0032774 380 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
cell activation GO:0001775 97 0.013
Rat
ion transmembrane transport GO:0034220 365 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.013
positive regulation of nervous system development GO:0051962 178 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
sensory perception GO:0007600 101 0.013
regulation of chronic inflammatory response GO:0002676 3 0.013
organ formation GO:0048645 3 0.012
cellular protein localization GO:0034613 122 0.012
lymphocyte activation GO:0046649 43 0.012
Rat
positive regulation of gene expression GO:0010628 244 0.012
jak stat cascade GO:0007259 26 0.012
cytokine production GO:0001816 61 0.012
metal ion homeostasis GO:0055065 186 0.012
lymphocyte migration GO:0072676 3 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
dendrite development GO:0016358 72 0.012
regulation of transcription dna templated GO:0006355 374 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
cellular component movement GO:0006928 248 0.012
divalent metal ion transport GO:0070838 132 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
protein secretion GO:0009306 34 0.012
sexual reproduction GO:0019953 148 0.011
reproductive process GO:0022414 372 0.011
organophosphate catabolic process GO:0046434 148 0.011
innate immune response GO:0045087 35 0.011
Rat
synaptic transmission glycinergic GO:0060012 2 0.011
inflammatory response to antigenic stimulus GO:0002437 18 0.011
cellular chemical homeostasis GO:0055082 247 0.011
eosinophil chemotaxis GO:0048245 3 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of response to stress GO:0080134 126 0.011
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of immunoglobulin production GO:0002637 4 0.011
regulation of cellular component organization GO:0051128 368 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
organic substance catabolic process GO:1901575 316 0.011
negative regulation of protein modification process GO:0031400 52 0.010
calcium mediated signaling GO:0019722 23 0.010
calcium ion homeostasis GO:0055074 162 0.010
regulation of innate immune response GO:0045088 15 0.010
Rat
macromolecule localization GO:0033036 252 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
regulation of phosphate metabolic process GO:0019220 349 0.010
regulation of ion transport GO:0043269 245 0.010
regulation of multicellular organismal development GO:2000026 376 0.010
positive regulation of renin secretion into blood stream GO:1900135 1 0.010
negative regulation of response to external stimulus GO:0032102 37 0.010
neurotransmitter gated ion channel clustering GO:0072578 3 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of intracellular transport GO:0032386 65 0.010
purine containing compound metabolic process GO:0072521 253 0.010
cartilage condensation GO:0001502 2 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010

Klra22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.011
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011