Rattus norvegicus

17 known processes

Smad5

SMAD family member 5

(Aliases: Madh5)

Smad5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 302 0.061
Rat
neuron differentiation GO:0030182 368 0.057
Rat
regulation of rna metabolic process GO:0051252 391 0.049
Rat
neuron development GO:0048666 286 0.046
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.044
Rat
anterior posterior pattern specification GO:0009952 1 0.043
rna biosynthetic process GO:0032774 380 0.043
Rat
negative regulation of gene expression GO:0010629 199 0.041
Rat
protein complex biogenesis GO:0070271 263 0.041
Rat
cellular component biogenesis GO:0044085 368 0.040
Rat
regulation of nervous system development GO:0051960 264 0.040
Rat
neuron projection development GO:0031175 273 0.040
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
Rat
regulation of cell differentiation GO:0045595 320 0.039
Rat
regulation of transcription dna templated GO:0006355 374 0.038
Rat
programmed cell death GO:0012501 392 0.037
Rat
developmental process involved in reproduction GO:0003006 159 0.037
regulation of neuron differentiation GO:0045664 208 0.035
Rat
macromolecular complex subunit organization GO:0043933 339 0.034
Rat
cellular component assembly GO:0022607 360 0.034
Rat
regulation of multicellular organismal development GO:2000026 376 0.034
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
Rat
axis specification GO:0009798 4 0.033
macromolecular complex assembly GO:0065003 273 0.033
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
Rat
regulation of neuron projection development GO:0010975 161 0.031
Rat
regulation of transforming growth factor beta3 production GO:0032910 2 0.031
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.031
Rat
cellular ketone metabolic process GO:0042180 51 0.031
regulation of neurogenesis GO:0050767 247 0.030
Rat
apoptotic process GO:0006915 381 0.030
Rat
carboxylic acid metabolic process GO:0019752 289 0.030
regulation of cellular component organization GO:0051128 368 0.030
Rat
transcription dna templated GO:0006351 377 0.030
Rat
positive regulation of gene expression GO:0010628 244 0.030
Rat
regulation of signal transduction GO:0009966 318 0.029
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.029
Rat
nucleic acid templated transcription GO:0097659 379 0.029
Rat
response to growth factor GO:0070848 189 0.029
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
Rat
amine metabolic process GO:0009308 38 0.028
regulation of apoptotic process GO:0042981 335 0.027
Rat
bmp signaling pathway GO:0030509 4 0.027
Rat
cellular amino acid metabolic process GO:0006520 107 0.027
regulation of cell development GO:0060284 263 0.026
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
Rat
cellular response to growth factor stimulus GO:0071363 162 0.026
Rat
intracellular signal transduction GO:0035556 314 0.025
Rat
reproductive process GO:0022414 372 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
Rat
cellular amine metabolic process GO:0044106 38 0.025
organelle organization GO:0006996 266 0.025
Rat
cellular response to endogenous stimulus GO:0071495 377 0.025
Rat
negative regulation of cell death GO:0060548 229 0.024
Rat
anatomical structure morphogenesis GO:0009653 298 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
Rat
regulation of protein metabolic process GO:0051246 289 0.024
Rat
negative regulation of biosynthetic process GO:0009890 168 0.024
Rat
positive regulation of biosynthetic process GO:0009891 319 0.024
Rat
neuron projection morphogenesis GO:0048812 122 0.023
Rat
rna metabolic process GO:0016070 406 0.023
Rat
single organism reproductive process GO:0044702 297 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
embryonic pattern specification GO:0009880 1 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.023
Rat
sex differentiation GO:0007548 113 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cell cycle GO:0007049 101 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.021
Rat
cellular response to stress GO:0033554 269 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
Rat
regulation of cell proliferation GO:0042127 359 0.020
Rat
protein phosphorylation GO:0006468 345 0.020
oxoacid metabolic process GO:0043436 290 0.020
positive regulation of developmental process GO:0051094 283 0.020
Rat
positive regulation of transcription dna templated GO:0045893 197 0.020
Rat
regulation of programmed cell death GO:0043067 341 0.020
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
Rat
negative regulation of metabolic process GO:0009892 331 0.019
Rat
protein complex subunit organization GO:0071822 302 0.019
Rat
protein complex assembly GO:0006461 263 0.019
Rat
positive regulation of response to stimulus GO:0048584 285 0.019
Rat
cellular macromolecular complex assembly GO:0034622 58 0.019
Rat
cellular component morphogenesis GO:0032989 155 0.019
Rat
negative regulation of rna metabolic process GO:0051253 123 0.018
Rat
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
Rat
positive regulation of cell projection organization GO:0031346 111 0.018
Rat
central nervous system development GO:0007417 311 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
response to hypoxia GO:0001666 231 0.017
Rat
reproductive system development GO:0061458 128 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
Rat
multi organism reproductive process GO:0044703 262 0.017
response to decreased oxygen levels GO:0036293 237 0.017
Rat
response to estrogen GO:0043627 232 0.017
Rat
negative regulation of apoptotic process GO:0043066 181 0.017
Rat
positive regulation of nervous system development GO:0051962 178 0.017
Rat
peptidyl amino acid modification GO:0018193 126 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
Rat
cellular response to oxygen containing compound GO:1901701 386 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
Rat
organic acid metabolic process GO:0006082 292 0.017
regulation of cell projection organization GO:0031344 175 0.017
Rat
positive regulation of neuron projection development GO:0010976 99 0.016
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.016
embryonic skeletal system development GO:0048706 3 0.016
ion transmembrane transport GO:0034220 365 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
Rat
reproduction GO:0000003 245 0.016
single organism biosynthetic process GO:0044711 342 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
Rat
histone h3 acetylation GO:0043966 2 0.015
multicellular organism reproduction GO:0032504 233 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of hormone levels GO:0010817 187 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
dna metabolic process GO:0006259 96 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
Rat
sexual reproduction GO:0019953 148 0.015
single organism organelle organization GO:1902589 180 0.014
Rat
positive regulation of cell proliferation GO:0008284 249 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
Rat
embryonic axis specification GO:0000578 1 0.014
response to oxidative stress GO:0006979 186 0.014
positive regulation of cell development GO:0010720 176 0.014
Rat
gonad development GO:0008406 104 0.014
regulation of cell cycle GO:0051726 73 0.014
response to inorganic substance GO:0010035 377 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
Rat
organic substance catabolic process GO:1901575 316 0.013
reproductive structure development GO:0048608 128 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
Rat
lipid metabolic process GO:0006629 283 0.013
transforming growth factor beta3 production GO:0032907 2 0.013
Rat
positive regulation of neurogenesis GO:0050769 165 0.013
Rat
gamete generation GO:0007276 124 0.013
positive regulation of cell communication GO:0010647 271 0.013
Rat
positive regulation of biomineral tissue development GO:0070169 4 0.013
Rat
regulation of phosphate metabolic process GO:0019220 349 0.013
Rat
cytoplasmic transport GO:0016482 115 0.013
locomotion GO:0040011 237 0.013
Rat
intracellular transport GO:0046907 185 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
Rat
metal ion transport GO:0030001 289 0.012
transmembrane transport GO:0055085 412 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
Rat
response to nutrient levels GO:0031667 370 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of molecular function GO:0065009 398 0.012
Rat
cell motility GO:0048870 202 0.012
Rat
multicellular organism growth GO:0035264 1 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
Rat
camera type eye morphogenesis GO:0048593 2 0.012
rhythmic process GO:0048511 156 0.012
catabolic process GO:0009056 351 0.012
response to oxygen levels GO:0070482 265 0.012
Rat
regulation of catalytic activity GO:0050790 304 0.012
Rat
cell part morphogenesis GO:0032990 123 0.012
Rat
gastrulation GO:0007369 2 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
gland development GO:0048732 155 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
cellular protein complex assembly GO:0043623 44 0.012
Rat
cell cell signaling GO:0007267 335 0.012
cellular response to organonitrogen compound GO:0071417 197 0.011
cellular chemical homeostasis GO:0055082 247 0.011
macromolecule localization GO:0033036 252 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
positive regulation of signaling GO:0023056 270 0.011
Rat
regulation of transferase activity GO:0051338 123 0.011
regulation of hormone secretion GO:0046883 106 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
response to hydrogen peroxide GO:0042542 89 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
regulation of protein modification process GO:0031399 194 0.011
secretion GO:0046903 307 0.011
cell cycle checkpoint GO:0000075 2 0.011
ras protein signal transduction GO:0007265 29 0.011
rna localization GO:0006403 4 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to mechanical stimulus GO:0009612 134 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
Rat
hormone secretion GO:0046879 115 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
Rat
regulation of phosphorylation GO:0042325 248 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.010
cellular macromolecule localization GO:0070727 122 0.010
chemical homeostasis GO:0048878 292 0.010
negative regulation of cell communication GO:0010648 158 0.010
growth GO:0040007 165 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
cell projection morphogenesis GO:0048858 123 0.010
Rat
cellular catabolic process GO:0044248 295 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.010
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.010
cell morphogenesis GO:0000902 142 0.010
Rat
regulation of organelle organization GO:0033043 80 0.010
Rat

Smad5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012