Rattus norvegicus

10 known processes

Smad6

SMAD family member 6

Smad6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.410
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.328
Rat
positive regulation of signal transduction GO:0009967 175 0.304
Rat
positive regulation of signaling GO:0023056 270 0.277
Rat
response to oxygen levels GO:0070482 265 0.245
Rat
regulation of apoptotic process GO:0042981 335 0.243
Rat
regulation of catalytic activity GO:0050790 304 0.223
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.222
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.219
Rat
regulation of transcription dna templated GO:0006355 374 0.202
Rat
response to hypoxia GO:0001666 231 0.199
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.194
Rat
regulation of programmed cell death GO:0043067 341 0.193
Rat
tissue development GO:0009888 252 0.192
Rat
positive regulation of transcription dna templated GO:0045893 197 0.191
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.184
Rat
intracellular signal transduction GO:0035556 314 0.183
Rat
regulation of protein phosphorylation GO:0001932 183 0.182
negative regulation of nucleic acid templated transcription GO:1903507 117 0.177
Rat
positive regulation of cell communication GO:0010647 271 0.171
Rat
regulation of molecular function GO:0065009 398 0.167
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.161
Rat
positive regulation of phosphorylation GO:0042327 177 0.154
negative regulation of gene expression GO:0010629 199 0.149
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.144
Rat
anatomical structure morphogenesis GO:0009653 298 0.141
Rat
response to inorganic substance GO:0010035 377 0.138
regulation of cell development GO:0060284 263 0.133
Rat
response to wounding GO:0009611 254 0.132
Rat
negative regulation of biosynthetic process GO:0009890 168 0.127
Rat
positive regulation of biosynthetic process GO:0009891 319 0.124
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.119
Rat
negative regulation of cell death GO:0060548 229 0.116
Rat
negative regulation of transcription dna templated GO:0045892 116 0.113
Rat
regulation of multicellular organismal development GO:2000026 376 0.112
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.109
Rat
regulation of protein modification process GO:0031399 194 0.109
neuron differentiation GO:0030182 368 0.107
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.105
regulation of cell proliferation GO:0042127 359 0.105
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.104
Rat
brain development GO:0007420 247 0.101
regulation of rna biosynthetic process GO:2001141 381 0.099
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.098
Rat
programmed cell death GO:0012501 392 0.098
Rat
positive regulation of cell differentiation GO:0045597 217 0.097
Rat
regulation of rna metabolic process GO:0051252 391 0.095
Rat
regulation of signal transduction GO:0009966 318 0.095
Rat
regulation of protein metabolic process GO:0051246 289 0.094
Rat
cellular response to oxygen containing compound GO:1901701 386 0.093
positive regulation of response to stimulus GO:0048584 285 0.092
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.091
Rat
positive regulation of cell proliferation GO:0008284 249 0.090
regulation of protein kinase activity GO:0045859 105 0.090
single organism reproductive process GO:0044702 297 0.089
Rat
reproduction GO:0000003 245 0.088
cell migration GO:0016477 197 0.086
Rat
response to acid chemical GO:0001101 222 0.086
negative regulation of rna metabolic process GO:0051253 123 0.085
Rat
response to nutrient levels GO:0031667 370 0.085
positive regulation of phosphorus metabolic process GO:0010562 262 0.085
Rat
response to decreased oxygen levels GO:0036293 237 0.083
Rat
transcription dna templated GO:0006351 377 0.082
Rat
locomotion GO:0040011 237 0.082
Rat
nucleic acid templated transcription GO:0097659 379 0.079
Rat
cellular response to lipid GO:0071396 201 0.079
cellular response to endogenous stimulus GO:0071495 377 0.077
Rat
positive regulation of mapk cascade GO:0043410 92 0.077
reproductive process GO:0022414 372 0.077
Rat
regulation of phosphorylation GO:0042325 248 0.075
rna metabolic process GO:0016070 406 0.075
Rat
cellular component morphogenesis GO:0032989 155 0.074
Rat
rna biosynthetic process GO:0032774 380 0.074
Rat
positive regulation of molecular function GO:0044093 230 0.073
Rat
regulation of neuron differentiation GO:0045664 208 0.072
Rat
apoptotic process GO:0006915 381 0.072
Rat
response to estradiol GO:0032355 164 0.071
positive regulation of rna biosynthetic process GO:1902680 197 0.070
Rat
negative regulation of metabolic process GO:0009892 331 0.069
Rat
cellular response to hormone stimulus GO:0032870 247 0.067
regulation of anatomical structure morphogenesis GO:0022603 141 0.067
Rat
response to lipopolysaccharide GO:0032496 191 0.062
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.062
Rat
cell motility GO:0048870 202 0.061
Rat
cellular response to stress GO:0033554 269 0.061
positive regulation of protein kinase activity GO:0045860 73 0.061
hepaticobiliary system development GO:0061008 90 0.061
cellular component assembly GO:0022607 360 0.060
Rat
regulation of neurogenesis GO:0050767 247 0.060
Rat
regulation of mapk cascade GO:0043408 116 0.059
neuron development GO:0048666 286 0.059
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.058
Rat
inorganic ion transmembrane transport GO:0098660 229 0.058
muscle cell proliferation GO:0033002 84 0.057
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.057
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.057
regulation of intracellular signal transduction GO:1902531 218 0.057
connective tissue development GO:0061448 33 0.056
regulation of nucleic acid templated transcription GO:1903506 380 0.055
Rat
organ regeneration GO:0031100 101 0.054
positive regulation of catalytic activity GO:0043085 184 0.054
Rat
ion transmembrane transport GO:0034220 365 0.053
cation transmembrane transport GO:0098655 263 0.053
enzyme linked receptor protein signaling pathway GO:0007167 116 0.053
Rat
localization of cell GO:0051674 202 0.052
Rat
cell part morphogenesis GO:0032990 123 0.052
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.052
Rat
regulation of phagocytosis engulfment GO:0060099 4 0.052
positive regulation of kinase activity GO:0033674 77 0.051
muscle tissue development GO:0060537 58 0.051
protein phosphorylation GO:0006468 345 0.051
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.050
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
Rat
sensory organ development GO:0007423 74 0.049
negative regulation of apoptotic process GO:0043066 181 0.049
Rat
liver development GO:0001889 90 0.049
negative regulation of rna biosynthetic process GO:1902679 118 0.049
Rat
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.048
central nervous system development GO:0007417 311 0.048
ion homeostasis GO:0050801 212 0.048
transmembrane transport GO:0055085 412 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.048
Rat
regulation of transferase activity GO:0051338 123 0.047
positive regulation of protein metabolic process GO:0051247 178 0.047
Rat
response to ethanol GO:0045471 162 0.047
sodium ion transmembrane transport GO:0035725 67 0.047
cardiovascular system development GO:0072358 134 0.047
organophosphate metabolic process GO:0019637 370 0.046
cellular homeostasis GO:0019725 252 0.046
regulation of cell migration GO:0030334 128 0.046
Rat
striated muscle tissue development GO:0014706 58 0.046
skeletal muscle tissue development GO:0007519 31 0.046
aging GO:0007568 241 0.046
positive regulation of cellular component organization GO:0051130 200 0.045
Rat
positive regulation of gene expression GO:0010628 244 0.045
Rat
positive regulation of programmed cell death GO:0043068 157 0.045
Rat
regulation of cell differentiation GO:0045595 320 0.045
Rat
response to molecule of bacterial origin GO:0002237 194 0.045
kidney development GO:0001822 67 0.044
Rat
response to corticosteroid GO:0031960 235 0.044
response to estrogen GO:0043627 232 0.044
cellular response to organic cyclic compound GO:0071407 202 0.043
regulation of cellular component organization GO:0051128 368 0.043
Rat
response to glucocorticoid GO:0051384 223 0.043
cellular component movement GO:0006928 248 0.043
Rat
regulation of kinase activity GO:0043549 117 0.042
positive regulation of cell development GO:0010720 176 0.042
Rat
response to external biotic stimulus GO:0043207 221 0.041
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.041
Rat
cellular component biogenesis GO:0044085 368 0.041
Rat
smooth muscle cell proliferation GO:0048659 77 0.041
urogenital system development GO:0001655 78 0.041
Rat
positive regulation of neurogenesis GO:0050769 165 0.040
Rat
response to bacterium GO:0009617 200 0.040
organelle organization GO:0006996 266 0.040
Rat
regeneration GO:0031099 163 0.040
positive regulation of transferase activity GO:0051347 81 0.040
circulatory system process GO:0003013 183 0.040
response to peptide hormone GO:0043434 278 0.040
response to nutrient GO:0007584 248 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
regulation of smooth muscle cell proliferation GO:0048660 75 0.038
gliogenesis GO:0042063 93 0.038
muscle structure development GO:0061061 87 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.038
Rat
head development GO:0060322 247 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
Rat
camera type eye development GO:0043010 48 0.037
response to extracellular stimulus GO:0009991 380 0.037
response to purine containing compound GO:0014074 126 0.037
response to peptide GO:1901652 292 0.037
regulation of blood pressure GO:0008217 83 0.036
single organism organelle organization GO:1902589 180 0.036
Rat
response to toxic substance GO:0009636 133 0.036
cell fate determination GO:0001709 2 0.035
positive regulation of hydrolase activity GO:0051345 86 0.035
Rat
cellular catabolic process GO:0044248 295 0.035
neuron projection development GO:0031175 273 0.035
Rat
regulation of system process GO:0044057 208 0.034
mapk cascade GO:0000165 140 0.034
Rat
bmp signaling pathway GO:0030509 4 0.034
Rat
response to cytokine GO:0034097 215 0.034
cardiac chamber development GO:0003205 1 0.033
amine metabolic process GO:0009308 38 0.033
homeostatic process GO:0042592 331 0.033
growth GO:0040007 165 0.033
positive regulation of phagocytosis engulfment GO:0060100 4 0.033
epithelium development GO:0060429 96 0.033
response to mechanical stimulus GO:0009612 134 0.033
regulation of homeostatic process GO:0032844 101 0.032
positive regulation of apoptotic process GO:0043065 154 0.032
Rat
heart development GO:0007507 72 0.032
sterol homeostasis GO:0055092 3 0.032
cellular response to external stimulus GO:0071496 118 0.032
organ formation GO:0048645 3 0.032
purine containing compound metabolic process GO:0072521 253 0.032
cellular amine metabolic process GO:0044106 38 0.032
organic acid transport GO:0015849 116 0.032
negative regulation of cell proliferation GO:0008285 119 0.031
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.031
forebrain development GO:0030900 98 0.031
protein complex assembly GO:0006461 263 0.031
Rat
signal transduction by phosphorylation GO:0023014 144 0.031
Rat
regulation of locomotion GO:0040012 148 0.031
Rat
eye development GO:0001654 50 0.031
response to metal ion GO:0010038 253 0.031
developmental process involved in reproduction GO:0003006 159 0.031
Rat
regulation of secretion GO:0051046 224 0.031
regulation of phosphate metabolic process GO:0019220 349 0.030
Rat
regulation of response to external stimulus GO:0032101 106 0.030
Rat
circulatory system development GO:0072359 134 0.030
cartilage development GO:0051216 22 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
positive regulation of nervous system development GO:0051962 178 0.030
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
respiratory system development GO:0060541 45 0.030
gland development GO:0048732 155 0.029
renal system development GO:0072001 67 0.029
Rat
cellular response to acid chemical GO:0071229 75 0.029
cellular ketone metabolic process GO:0042180 51 0.028
heart morphogenesis GO:0003007 3 0.028
regulation of cellular component movement GO:0051270 150 0.028
Rat
alcohol metabolic process GO:0006066 77 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.028
macromolecule localization GO:0033036 252 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
catabolic process GO:0009056 351 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.026
salivary gland development GO:0007431 3 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
skeletal system development GO:0001501 41 0.026
cell morphogenesis GO:0000902 142 0.026
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.026
regulation of secretion by cell GO:1903530 208 0.025
positive regulation of developmental process GO:0051094 283 0.025
Rat
activation of protein kinase activity GO:0032147 47 0.025
regulation of hydrolase activity GO:0051336 143 0.025
Rat
multicellular organismal reproductive process GO:0048609 233 0.025
embryonic skeletal system development GO:0048706 3 0.025
single organism biosynthetic process GO:0044711 342 0.025
cellular chemical homeostasis GO:0055082 247 0.025
negative regulation of molecular function GO:0044092 133 0.024
response to alkaloid GO:0043279 132 0.024
cell adhesion GO:0007155 110 0.024
Rat
nucleotide metabolic process GO:0009117 279 0.024
cellular lipid metabolic process GO:0044255 208 0.024
negative regulation of cellular protein metabolic process GO:0032269 106 0.024
erk1 and erk2 cascade GO:0070371 48 0.024
cellular response to glucocorticoid stimulus GO:0071385 68 0.024
positive regulation of organelle organization GO:0010638 48 0.024
Rat
cholesterol homeostasis GO:0042632 3 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
reproductive structure development GO:0048608 128 0.023
small molecule biosynthetic process GO:0044283 124 0.023
tube development GO:0035295 89 0.023
establishment of protein localization GO:0045184 141 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
negative regulation of catalytic activity GO:0043086 103 0.023
cell projection organization GO:0030030 302 0.023
Rat
nucleoside metabolic process GO:0009116 179 0.023
immune system process GO:0002376 204 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.023
cellular response to peptide GO:1901653 133 0.022
regulation of tube size GO:0035150 89 0.022
anterior posterior pattern specification GO:0009952 1 0.022
organ morphogenesis GO:0009887 75 0.022
limbic system development GO:0021761 38 0.022
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.022
regulation of organ formation GO:0003156 2 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
Rat
multicellular organism reproduction GO:0032504 233 0.022
neuron apoptotic process GO:0051402 88 0.021
epithelial cell differentiation GO:0030855 71 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
Rat
regulation of hormone levels GO:0010817 187 0.021
regulation of anatomical structure size GO:0090066 135 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
cation homeostasis GO:0055080 195 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
Rat
carboxylic acid transport GO:0046942 115 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
regulation of cell motility GO:2000145 131 0.021
Rat
embryo development GO:0009790 49 0.021
eye morphogenesis GO:0048592 4 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
chemical homeostasis GO:0048878 292 0.020
reproductive system development GO:0061458 128 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
Rat
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.020
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 3 0.020
regulation of map kinase activity GO:0043405 53 0.020
response to growth factor GO:0070848 189 0.020
Rat
neuron projection morphogenesis GO:0048812 122 0.020
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.020
action potential GO:0001508 54 0.019
t cell tolerance induction GO:0002517 3 0.019
amide transport GO:0042886 105 0.019
regulation of ion transmembrane transport GO:0034765 121 0.019
response to camp GO:0051591 91 0.019
secretion by cell GO:0032940 248 0.019
blood vessel morphogenesis GO:0048514 58 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
regulation of growth GO:0040008 105 0.019
response to hydrogen peroxide GO:0042542 89 0.019
positive regulation of cell death GO:0010942 184 0.018
Rat
protein localization GO:0008104 191 0.018
sex differentiation GO:0007548 113 0.018
Rat
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.018
glial cell differentiation GO:0010001 65 0.018
regulation of hormone secretion GO:0046883 106 0.018
response to monosaccharide GO:0034284 159 0.018
response to hyperoxia GO:0055093 45 0.018
vitamin a metabolic process GO:0006776 2 0.018
response to oxidative stress GO:0006979 186 0.018
metal ion transport GO:0030001 289 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
Rat
response to other organism GO:0051707 220 0.018
oxoacid metabolic process GO:0043436 290 0.017
epithelial cell proliferation GO:0050673 54 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
Rat
ribonucleotide metabolic process GO:0009259 231 0.017
cellular response to alcohol GO:0097306 87 0.017
appendage morphogenesis GO:0035107 4 0.017
biological adhesion GO:0022610 110 0.017
Rat
response to nicotine GO:0035094 51 0.017
lipid metabolic process GO:0006629 283 0.017
cellular cation homeostasis GO:0030003 180 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
Rat
cell projection morphogenesis GO:0048858 123 0.017
Rat
organic acid metabolic process GO:0006082 292 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
response to retinoic acid GO:0032526 63 0.017
response to glucose GO:0009749 136 0.017
regulation of nervous system development GO:0051960 264 0.017
Rat
regulation of response to stress GO:0080134 126 0.017
cellular response to oxygen levels GO:0071453 60 0.017
pallium development GO:0021543 42 0.017
morphogenesis of embryonic epithelium GO:0016331 3 0.017
response to axon injury GO:0048678 59 0.016
negative regulation of neuron death GO:1901215 69 0.016
protein complex subunit organization GO:0071822 302 0.016
Rat
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.016
Rat
sensory perception of pain GO:0019233 73 0.016
positive regulation of protein modification process GO:0031401 142 0.016
response to carbohydrate GO:0009743 183 0.016
cellular response to drug GO:0035690 30 0.016
negative regulation of transport GO:0051051 136 0.016
secretion GO:0046903 307 0.016
cell growth GO:0016049 104 0.016
response to increased oxygen levels GO:0036296 45 0.016
embryonic pattern specification GO:0009880 1 0.016
vesicle mediated transport GO:0016192 181 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
glomerulus development GO:0032835 10 0.015
specification of organ identity GO:0010092 2 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
Rat
glycosaminoglycan biosynthetic process GO:0006024 4 0.015
mesenchymal cell proliferation GO:0010463 4 0.015
posttranscriptional regulation of gene expression GO:0010608 37 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
negative regulation of signal transduction GO:0009968 83 0.015
coronary vasculature morphogenesis GO:0060977 3 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
response to fatty acid GO:0070542 65 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
multi organism reproductive process GO:0044703 262 0.015
muscle organ development GO:0007517 50 0.015
monocarboxylic acid transport GO:0015718 52 0.015
olfactory bulb interneuron differentiation GO:0021889 1 0.015
positive regulation of cytoskeleton organization GO:0051495 26 0.014
Rat
regulation of cellular localization GO:0060341 263 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
response to vitamin GO:0033273 131 0.014
protein localization to organelle GO:0033365 57 0.014
regulation of erk1 and erk2 cascade GO:0070372 41 0.014
transmission of nerve impulse GO:0019226 42 0.014
palate development GO:0060021 2 0.014
cellular ion homeostasis GO:0006873 184 0.014
positive regulation of map kinase activity GO:0043406 46 0.014
regulation of neuron projection development GO:0010975 161 0.014
Rat
response to radiation GO:0009314 137 0.014
regulation of blood vessel size GO:0050880 89 0.014
vasculature development GO:0001944 70 0.014
phospholipid metabolic process GO:0006644 61 0.014
angiogenesis GO:0001525 53 0.014
gastrulation GO:0007369 2 0.014
placenta development GO:0001890 22 0.014
protein targeting GO:0006605 61 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
hippocampus development GO:0021766 30 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
cell type specific apoptotic process GO:0097285 134 0.014
Rat
purine nucleoside catabolic process GO:0006152 124 0.014
phasic smooth muscle contraction GO:0014821 3 0.014
muscle tissue morphogenesis GO:0060415 1 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
gonad development GO:0008406 104 0.013
embryonic skeletal system morphogenesis GO:0048704 3 0.013
digestive system development GO:0055123 41 0.013
response to vitamin a GO:0033189 36 0.013
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.013
apoptotic signaling pathway GO:0097190 27 0.013
Rat
negative regulation of response to stimulus GO:0048585 155 0.013
response to organophosphorus GO:0046683 102 0.013
regulation of body fluid levels GO:0050878 90 0.013
glomerular mesangium development GO:0072109 4 0.013
regulation of epithelial cell proliferation GO:0050678 49 0.013
regulation of transmembrane transport GO:0034762 122 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
regulation of protein localization GO:0032880 81 0.013
cell cycle process GO:0022402 57 0.013
dendrite development GO:0016358 72 0.013
Rat
development of primary male sexual characteristics GO:0046546 59 0.013
muscle organ morphogenesis GO:0048644 1 0.013
glomerulus morphogenesis GO:0072102 1 0.013
blood circulation GO:0008015 183 0.013
protein complex biogenesis GO:0070271 263 0.013
Rat
camera type eye morphogenesis GO:0048593 2 0.012
organic hydroxy compound transport GO:0015850 77 0.012
neuronal action potential GO:0019228 35 0.012
retina development in camera type eye GO:0060041 27 0.012
digestive tract development GO:0048565 39 0.012
organic substance catabolic process GO:1901575 316 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
sensory perception GO:0007600 101 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.012
vitamin d receptor signaling pathway GO:0070561 1 0.012
multi multicellular organism process GO:0044706 138 0.012
cellular response to hypoxia GO:0071456 51 0.012
odontogenesis GO:0042476 32 0.012
regulation of peptidase activity GO:0052547 55 0.012
Rat
actin filament based process GO:0030029 86 0.012
Rat
nitrogen compound transport GO:0071705 229 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
embryonic placenta development GO:0001892 1 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
sensory perception of bitter taste GO:0050913 4 0.012
mesoderm development GO:0007498 2 0.012
phospholipid biosynthetic process GO:0008654 29 0.012
positive regulation of tolerance induction GO:0002645 1 0.012
peptide transport GO:0015833 97 0.012
hormone transport GO:0009914 121 0.012
positive regulation of locomotion GO:0040017 102 0.012
Rat
response to hexose GO:0009746 144 0.012
neurological system process GO:0050877 219 0.012
potassium ion transport GO:0006813 97 0.012
positive regulation of epidermis development GO:0045684 1 0.011
blood vessel development GO:0001568 69 0.011
regulation of cell cycle GO:0051726 73 0.011
embryonic limb morphogenesis GO:0030326 4 0.011
regulation of heart contraction GO:0008016 48 0.011
development of primary sexual characteristics GO:0045137 107 0.011
ossification GO:0001503 70 0.011
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
skeletal muscle organ development GO:0060538 33 0.011
cardiac ventricle development GO:0003231 1 0.011
inner ear morphogenesis GO:0042472 1 0.011
cytoskeleton organization GO:0007010 111 0.011
Rat
heterocycle catabolic process GO:0046700 167 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
Rat
actin cytoskeleton organization GO:0030036 73 0.011
Rat
ras protein signal transduction GO:0007265 29 0.011
negative regulation of signaling GO:0023057 157 0.011
protein maturation GO:0051604 68 0.011
Rat
organic anion transport GO:0015711 132 0.011
cellular glucose homeostasis GO:0001678 66 0.011
peptide hormone secretion GO:0030072 84 0.011
vasodilation GO:0042311 44 0.011
positive regulation of focal adhesion assembly GO:0051894 2 0.011
Rat
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
cell cycle GO:0007049 101 0.011
negative regulation of developmental process GO:0051093 125 0.011
inflammatory response GO:0006954 150 0.011
regulation of axonogenesis GO:0050770 37 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
lens fiber cell differentiation GO:0070306 3 0.011
regulation of blood circulation GO:1903522 110 0.011
response to biotic stimulus GO:0009607 226 0.011
positive regulation of secretion GO:0051047 140 0.011

Smad6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
disease of cellular proliferation DOID:14566 0 0.011