Rattus norvegicus

9 known processes

Atp6ap1

ATPase, H+ transporting, lysosomal accessory protein 1

(Aliases: C7-1,Atp6s1)

Atp6ap1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
histamine secretion by mast cell GO:0002553 3 0.478
vesicle mediated transport GO:0016192 181 0.439
endocytosis GO:0006897 84 0.354
response to peptide GO:1901652 292 0.146
regulation of transcription dna templated GO:0006355 374 0.144
cellular response to oxygen containing compound GO:1901701 386 0.134
histamine production involved in inflammatory response GO:0002349 3 0.120
nucleic acid templated transcription GO:0097659 379 0.112
nitrogen compound transport GO:0071705 229 0.111
mast cell activation GO:0045576 15 0.110
negative regulation of multicellular organismal process GO:0051241 203 0.109
response to nutrient levels GO:0031667 370 0.104
regulation of nucleic acid templated transcription GO:1903506 380 0.101
response to hypoxia GO:0001666 231 0.097
mast cell mediated immunity GO:0002448 10 0.095
response to peptide hormone GO:0043434 278 0.093
histamine secretion involved in inflammatory response GO:0002441 3 0.090
secretion by cell GO:0032940 248 0.088
protein targeting GO:0006605 61 0.086
reproductive process GO:0022414 372 0.080
single organism catabolic process GO:0044712 283 0.079
regulation of cell differentiation GO:0045595 320 0.078
cellular macromolecule localization GO:0070727 122 0.077
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.076
leukocyte activation involved in immune response GO:0002366 16 0.076
leukocyte degranulation GO:0043299 12 0.075
signal release GO:0023061 145 0.074
lysosome localization GO:0032418 10 0.073
production of molecular mediator involved in inflammatory response GO:0002532 5 0.073
mast cell degranulation GO:0043303 10 0.071
cellular catabolic process GO:0044248 295 0.071
regulation of rna biosynthetic process GO:2001141 381 0.070
head development GO:0060322 247 0.069
rna biosynthetic process GO:0032774 380 0.068
transcription dna templated GO:0006351 377 0.065
brain development GO:0007420 247 0.065
rna metabolic process GO:0016070 406 0.062
regulation of cellular component organization GO:0051128 368 0.059
regulation of neuron projection development GO:0010975 161 0.057
macromolecule localization GO:0033036 252 0.056
single organism membrane organization GO:0044802 74 0.053
intracellular transport GO:0046907 185 0.051
response to insulin GO:0032868 133 0.050
organic acid metabolic process GO:0006082 292 0.050
response to cytokine GO:0034097 215 0.050
cellular response to external stimulus GO:0071496 118 0.050
transcription from rna polymerase ii promoter GO:0006366 252 0.049
reproductive system development GO:0061458 128 0.048
neuron projection development GO:0031175 273 0.047
negative regulation of gene expression GO:0010629 199 0.047
regulation of rna metabolic process GO:0051252 391 0.046
cellular response to peptide hormone stimulus GO:0071375 120 0.046
response to extracellular stimulus GO:0009991 380 0.046
positive regulation of cell differentiation GO:0045597 217 0.045
cell activation involved in immune response GO:0002263 16 0.045
cellular response to endogenous stimulus GO:0071495 377 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
regulation of hormone levels GO:0010817 187 0.042
synaptic transmission GO:0007268 235 0.041
response to hexose GO:0009746 144 0.041
myeloid leukocyte mediated immunity GO:0002444 12 0.039
response to monosaccharide GO:0034284 159 0.039
catabolic process GO:0009056 351 0.039
ion homeostasis GO:0050801 212 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.038
cellular response to insulin stimulus GO:0032869 81 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
cellular protein localization GO:0034613 122 0.037
multi organism reproductive process GO:0044703 262 0.037
cellular component biogenesis GO:0044085 368 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.036
organophosphate metabolic process GO:0019637 370 0.036
regulated secretory pathway GO:0045055 17 0.035
central nervous system development GO:0007417 311 0.035
protein oligomerization GO:0051259 191 0.034
positive regulation of cell development GO:0010720 176 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
regulation of cell development GO:0060284 263 0.033
inflammatory response GO:0006954 150 0.033
carbohydrate derivative biosynthetic process GO:1901137 124 0.033
regulation of neurological system process GO:0031644 43 0.033
response to inorganic substance GO:0010035 377 0.033
regulation of synaptic transmission GO:0050804 141 0.032
response to lipopolysaccharide GO:0032496 191 0.032
response to oxygen levels GO:0070482 265 0.032
myeloid cell activation involved in immune response GO:0002275 13 0.032
cellular response to nitrogen compound GO:1901699 210 0.031
response to growth factor GO:0070848 189 0.031
oxoacid metabolic process GO:0043436 290 0.031
cellular response to mechanical stimulus GO:0071260 48 0.031
response to glucose GO:0009749 136 0.031
secretion GO:0046903 307 0.030
cell cell signaling GO:0007267 335 0.030
regulation of signal transduction GO:0009966 318 0.030
positive regulation of developmental process GO:0051094 283 0.030
reproduction GO:0000003 245 0.030
hormone secretion GO:0046879 115 0.030
regulation of cell projection organization GO:0031344 175 0.029
female pregnancy GO:0007565 122 0.029
receptor mediated endocytosis GO:0006898 42 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
negative regulation of nucleic acid templated transcription GO:1903507 117 0.028
autophagic cell death GO:0048102 4 0.028
establishment of protein localization GO:0045184 141 0.028
histamine secretion GO:0001821 8 0.028
growth GO:0040007 165 0.027
response to decreased oxygen levels GO:0036293 237 0.027
regulation of nervous system development GO:0051960 264 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
response to other organism GO:0051707 220 0.026
proteolysis GO:0006508 175 0.026
positive regulation of gene expression GO:0010628 244 0.026
response to carbohydrate GO:0009743 183 0.026
response to oxidative stress GO:0006979 186 0.026
negative regulation of cell development GO:0010721 82 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.026
response to camp GO:0051591 91 0.025
negative regulation of metabolic process GO:0009892 331 0.025
protein complex biogenesis GO:0070271 263 0.024
myeloid leukocyte activation GO:0002274 36 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
negative regulation of cell differentiation GO:0045596 99 0.023
cellular response to stress GO:0033554 269 0.023
regulation of anatomical structure size GO:0090066 135 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
ras protein signal transduction GO:0007265 29 0.023
negative regulation of signaling GO:0023057 157 0.023
membrane organization GO:0061024 94 0.022
regulation of neuron differentiation GO:0045664 208 0.022
sodium ion transmembrane transport GO:0035725 67 0.022
multicellular organism growth GO:0035264 1 0.022
hormone transport GO:0009914 121 0.022
cellular amine metabolic process GO:0044106 38 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
homeostatic process GO:0042592 331 0.022
tissue development GO:0009888 252 0.022
developmental growth GO:0048589 100 0.022
positive regulation of biosynthetic process GO:0009891 319 0.021
protein localization to organelle GO:0033365 57 0.021
protein heterooligomerization GO:0051291 89 0.021
single organism intracellular transport GO:1902582 166 0.020
regulation of axonogenesis GO:0050770 37 0.020
regulation of molecular function GO:0065009 398 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
negative regulation of neuron differentiation GO:0045665 62 0.020
cellular metal ion homeostasis GO:0006875 172 0.019
metal ion homeostasis GO:0055065 186 0.019
tetrahydrofolate metabolic process GO:0046653 9 0.019
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.019
neuron differentiation GO:0030182 368 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
regulation of apoptotic process GO:0042981 335 0.019
single organism reproductive process GO:0044702 297 0.019
multicellular organism reproduction GO:0032504 233 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.018
immune response GO:0006955 104 0.018
regulation of growth GO:0040008 105 0.018
cation transport GO:0006812 382 0.018
protein complex assembly GO:0006461 263 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
negative regulation of nervous system development GO:0051961 79 0.017
macromolecular complex assembly GO:0065003 273 0.017
dendrite development GO:0016358 72 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
single organism biosynthetic process GO:0044711 342 0.017
cell fate determination GO:0001709 2 0.017
response to amine GO:0014075 46 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
protein localization to membrane GO:0072657 36 0.017
cellular response to extracellular stimulus GO:0031668 73 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
protein localization GO:0008104 191 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
cellular cation homeostasis GO:0030003 180 0.016
organic substance catabolic process GO:1901575 316 0.016
rhythmic process GO:0048511 156 0.016
macroautophagy GO:0016236 4 0.016
protein complex subunit organization GO:0071822 302 0.015
chemical homeostasis GO:0048878 292 0.015
regulation of body fluid levels GO:0050878 90 0.015
defense response GO:0006952 194 0.015
negative regulation of transport GO:0051051 136 0.015
regulation of sensory perception GO:0051931 29 0.015
apoptotic process GO:0006915 381 0.015
organelle organization GO:0006996 266 0.015
antigen processing and presentation GO:0019882 2 0.015
cellular response to oxidative stress GO:0034599 76 0.015
negative regulation of neuron projection development GO:0010977 46 0.015
nucleotide metabolic process GO:0009117 279 0.015
macromolecule catabolic process GO:0009057 58 0.015
response to wounding GO:0009611 254 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
response to mechanical stimulus GO:0009612 134 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
sensory perception of pain GO:0019233 73 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
intracellular protein transport GO:0006886 79 0.014
negative regulation of cell communication GO:0010648 158 0.014
rab protein signal transduction GO:0032482 1 0.014
golgi vesicle transport GO:0048193 22 0.014
organelle localization GO:0051640 55 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
regeneration GO:0031099 163 0.014
epithelium development GO:0060429 96 0.014
mast cell activation involved in immune response GO:0002279 10 0.013
response to nutrient GO:0007584 248 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
protein prenylation GO:0018342 4 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of angiotensin levels in blood GO:0002002 2 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
immune system process GO:0002376 204 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
sexual reproduction GO:0019953 148 0.013
reproductive structure development GO:0048608 128 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.013
alcohol metabolic process GO:0006066 77 0.013
cellular response to interleukin 1 GO:0071347 37 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
cellular modified amino acid biosynthetic process GO:0042398 18 0.013
cell projection organization GO:0030030 302 0.013
response to hyperoxia GO:0055093 45 0.013
response to external biotic stimulus GO:0043207 221 0.013
response to increased oxygen levels GO:0036296 45 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
neuron development GO:0048666 286 0.013
response to activity GO:0014823 73 0.012
single organism cellular localization GO:1902580 102 0.012
cytoplasmic transport GO:0016482 115 0.012
response to radiation GO:0009314 137 0.012
multicellular organismal catabolic process GO:0044243 2 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular ion homeostasis GO:0006873 184 0.012
cellular homeostasis GO:0019725 252 0.012
glycogen metabolic process GO:0005977 23 0.012
cell cycle GO:0007049 101 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
regulation of cellular localization GO:0060341 263 0.012
response to interleukin 1 GO:0070555 55 0.012
neurological system process GO:0050877 219 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
protein homooligomerization GO:0051260 91 0.012
organelle fusion GO:0048284 17 0.012
endosome to lysosome transport GO:0008333 6 0.012
developmental process involved in reproduction GO:0003006 159 0.012
lipid biosynthetic process GO:0008610 128 0.011
programmed cell death GO:0012501 392 0.011
response to organophosphorus GO:0046683 102 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
amine metabolic process GO:0009308 38 0.011
taxis GO:0042330 67 0.011
cellular response to nutrient levels GO:0031669 60 0.011
positive regulation of cell death GO:0010942 184 0.011
membrane depolarization during action potential GO:0086010 1 0.011
circadian rhythm GO:0007623 88 0.011
positive regulation of nervous system development GO:0051962 178 0.011
response to vitamin GO:0033273 131 0.011
er to golgi vesicle mediated transport GO:0006888 10 0.011
cellular amino acid biosynthetic process GO:0008652 32 0.011
rna localization GO:0006403 4 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
cellular response to peptide GO:1901653 133 0.011
exocytosis GO:0006887 60 0.011
protein processing GO:0016485 68 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
catecholamine secretion GO:0050432 33 0.011
cell growth GO:0016049 104 0.011
meiotic cell cycle process GO:1903046 3 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
regulation of sensory perception of pain GO:0051930 29 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
purine ribonucleoside biosynthetic process GO:0046129 21 0.010
regulation of neurogenesis GO:0050767 247 0.010
regulation of organelle organization GO:0033043 80 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
regulation of cell proliferation GO:0042127 359 0.010
multi multicellular organism process GO:0044706 138 0.010
sex differentiation GO:0007548 113 0.010
learning or memory GO:0007611 90 0.010
calcium ion homeostasis GO:0055074 162 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
purine containing compound metabolic process GO:0072521 253 0.010

Atp6ap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.049
disease of metabolism DOID:0014667 0 0.029
sensory system disease DOID:0050155 0 0.018
non syndromic intellectual disability DOID:0050889 0 0.013
disease of mental health DOID:150 0 0.013
developmental disorder of mental health DOID:0060037 0 0.013
specific developmental disorder DOID:0060038 0 0.013
non specific x linked mental retardation DOID:0050776 0 0.013
intellectual disability DOID:1059 0 0.013