Rattus norvegicus

0 known processes

Lrfn4

leucine rich repeat and fibronectin type III domain containing 4

Lrfn4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.155
response to extracellular stimulus GO:0009991 380 0.125
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.101
regulation of molecular function GO:0065009 398 0.100
regulation of neurogenesis GO:0050767 247 0.081
response to peptide GO:1901652 292 0.079
endocytosis GO:0006897 84 0.071
response to cytokine GO:0034097 215 0.067
nucleic acid templated transcription GO:0097659 379 0.065
cell projection organization GO:0030030 302 0.064
negative regulation of metabolic process GO:0009892 331 0.063
regulation of rna metabolic process GO:0051252 391 0.061
regulation of neuron differentiation GO:0045664 208 0.056
positive regulation of signaling GO:0023056 270 0.056
locomotion GO:0040011 237 0.053
regulation of cell proliferation GO:0042127 359 0.053
response to nutrient levels GO:0031667 370 0.052
positive regulation of developmental process GO:0051094 283 0.050
protein localization GO:0008104 191 0.050
neuron projection morphogenesis GO:0048812 122 0.050
behavior GO:0007610 205 0.049
rna biosynthetic process GO:0032774 380 0.049
lipid metabolic process GO:0006629 283 0.049
single organism intracellular transport GO:1902582 166 0.048
neuron development GO:0048666 286 0.047
regulation of signal transduction GO:0009966 318 0.046
regulation of protein modification process GO:0031399 194 0.044
secretion by cell GO:0032940 248 0.043
regulation of nucleic acid templated transcription GO:1903506 380 0.043
positive regulation of rna metabolic process GO:0051254 203 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
tissue development GO:0009888 252 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
regulation of cell differentiation GO:0045595 320 0.041
regulation of rna biosynthetic process GO:2001141 381 0.041
regulation of transcription dna templated GO:0006355 374 0.040
negative regulation of biosynthetic process GO:0009890 168 0.039
positive regulation of cell death GO:0010942 184 0.039
negative regulation of response to stimulus GO:0048585 155 0.039
adult locomotory behavior GO:0008344 4 0.039
vesicle mediated transport GO:0016192 181 0.039
cognition GO:0050890 92 0.038
cell projection morphogenesis GO:0048858 123 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
positive regulation of response to stimulus GO:0048584 285 0.038
regulation of cell projection organization GO:0031344 175 0.037
single organism behavior GO:0044708 130 0.037
positive regulation of transport GO:0051050 245 0.035
reproductive process GO:0022414 372 0.035
secretion GO:0046903 307 0.035
dendrite development GO:0016358 72 0.034
metal ion transport GO:0030001 289 0.033
synaptic transmission GO:0007268 235 0.033
regulation of nervous system development GO:0051960 264 0.033
regulation of secretion GO:0051046 224 0.033
chemosensory behavior GO:0007635 2 0.033
regulation of proteasomal protein catabolic process GO:0061136 4 0.033
neuron projection development GO:0031175 273 0.032
negative regulation of rna metabolic process GO:0051253 123 0.032
protein complex biogenesis GO:0070271 263 0.032
cellular component assembly GO:0022607 360 0.032
central nervous system development GO:0007417 311 0.032
regulation of synapse maturation GO:0090128 2 0.032
response to inorganic substance GO:0010035 377 0.031
cellular response to oxygen containing compound GO:1901701 386 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
positive regulation of neuron differentiation GO:0045666 126 0.029
regulation of vesicle mediated transport GO:0060627 81 0.029
regulation of cellular localization GO:0060341 263 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
multi organism reproductive process GO:0044703 262 0.028
regulation of cellular component organization GO:0051128 368 0.028
neuron death GO:0070997 127 0.028
intracellular signal transduction GO:0035556 314 0.028
response to monosaccharide GO:0034284 159 0.028
spindle organization GO:0007051 2 0.027
negative regulation of signaling GO:0023057 157 0.027
transcription dna templated GO:0006351 377 0.027
regulation of cell development GO:0060284 263 0.027
transmembrane transport GO:0055085 412 0.027
positive regulation of secretion by cell GO:1903532 128 0.026
organelle organization GO:0006996 266 0.026
positive regulation of gene expression GO:0010628 244 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
cell migration GO:0016477 197 0.026
regulation of neuron projection development GO:0010975 161 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
female pregnancy GO:0007565 122 0.025
synaptic growth at neuromuscular junction GO:0051124 1 0.025
heart morphogenesis GO:0003007 3 0.025
reproductive system development GO:0061458 128 0.025
response to estradiol GO:0032355 164 0.025
negative regulation of developmental process GO:0051093 125 0.024
regulation of secretion by cell GO:1903530 208 0.024
response to vitamin GO:0033273 131 0.024
regulation of jnk cascade GO:0046328 19 0.024
regulation of locomotion GO:0040012 148 0.024
regulation of dendrite development GO:0050773 59 0.024
response to hydrogen peroxide GO:0042542 89 0.023
gland development GO:0048732 155 0.023
response to hypoxia GO:0001666 231 0.023
macromolecular complex assembly GO:0065003 273 0.023
response to acid chemical GO:0001101 222 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
oxoacid metabolic process GO:0043436 290 0.023
positive regulation of nervous system development GO:0051962 178 0.022
positive regulation of cell communication GO:0010647 271 0.022
single organism reproductive process GO:0044702 297 0.022
programmed cell death GO:0012501 392 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
cellular cation homeostasis GO:0030003 180 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
reproduction GO:0000003 245 0.021
response to radiation GO:0009314 137 0.021
cellular ketone metabolic process GO:0042180 51 0.021
negative regulation of signal transduction GO:0009968 83 0.021
protein phosphorylation GO:0006468 345 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
regulation of synaptic vesicle endocytosis GO:1900242 1 0.021
axon development GO:0061564 96 0.021
brain development GO:0007420 247 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
response to wounding GO:0009611 254 0.021
cell cell signaling GO:0007267 335 0.021
rhythmic process GO:0048511 156 0.021
head development GO:0060322 247 0.020
neuron differentiation GO:0030182 368 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
postsynaptic density protein 95 clustering GO:0097119 2 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
chemical homeostasis GO:0048878 292 0.020
associative learning GO:0008306 19 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
negative regulation of molecular function GO:0044092 133 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of cell migration GO:0030334 128 0.019
response to nutrient GO:0007584 248 0.019
cardiac chamber development GO:0003205 1 0.019
learning or memory GO:0007611 90 0.019
single organism biosynthetic process GO:0044711 342 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
response to peptide hormone GO:0043434 278 0.019
regulation of apoptotic process GO:0042981 335 0.019
apoptotic process GO:0006915 381 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
positive regulation of cell projection organization GO:0031346 111 0.018
cellular component morphogenesis GO:0032989 155 0.018
response to oxygen levels GO:0070482 265 0.018
protein complex subunit organization GO:0071822 302 0.018
dendrite morphogenesis GO:0048813 43 0.018
positive regulation of kinase activity GO:0033674 77 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
response to reactive oxygen species GO:0000302 120 0.018
synapse organization GO:0050808 46 0.018
protein transport GO:0015031 132 0.018
olfactory learning GO:0008355 1 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
protein complex assembly GO:0006461 263 0.018
cellular response to growth factor stimulus GO:0071363 162 0.017
response to metal ion GO:0010038 253 0.017
negative regulation of gene expression GO:0010629 199 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
mitotic spindle organization GO:0007052 2 0.017
multicellular organism growth GO:0035264 1 0.017
regulation of ion transmembrane transport GO:0034765 121 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of molecular function GO:0044093 230 0.017
ion transmembrane transport GO:0034220 365 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
response to decreased oxygen levels GO:0036293 237 0.017
homeostatic process GO:0042592 331 0.017
regeneration GO:0031099 163 0.017
cellular response to external stimulus GO:0071496 118 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
cell part morphogenesis GO:0032990 123 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
cellular response to stress GO:0033554 269 0.016
cell cycle GO:0007049 101 0.016
negative regulation of cell development GO:0010721 82 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.016
terminal button organization GO:0072553 3 0.016
response to growth factor GO:0070848 189 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
negative regulation of neurogenesis GO:0050768 78 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
motor neuron axon guidance GO:0008045 1 0.015
protein oligomerization GO:0051259 191 0.015
multicellular organism reproduction GO:0032504 233 0.015
epithelium development GO:0060429 96 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
olfactory behavior GO:0042048 2 0.015
proteolysis GO:0006508 175 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
regulation of transferase activity GO:0051338 123 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
centrosome organization GO:0051297 1 0.015
regulation of phosphorylation GO:0042325 248 0.015
calcium ion homeostasis GO:0055074 162 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
biological adhesion GO:0022610 110 0.015
response to hexose GO:0009746 144 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
cellular homeostasis GO:0019725 252 0.015
cellular amino acid metabolic process GO:0006520 107 0.014
organic acid metabolic process GO:0006082 292 0.014
positive regulation of signal transduction GO:0009967 175 0.014
salivary gland development GO:0007431 3 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
regulation of neuron death GO:1901214 115 0.014
axis specification GO:0009798 4 0.014
growth GO:0040007 165 0.014
regulation of programmed cell death GO:0043067 341 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
neurological system process GO:0050877 219 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
regulation of protein metabolic process GO:0051246 289 0.014
amine metabolic process GO:0009308 38 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
negative regulation of transport GO:0051051 136 0.014
cellular lipid metabolic process GO:0044255 208 0.014
entrainment of circadian clock GO:0009649 3 0.013
circadian regulation of gene expression GO:0032922 3 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
negative regulation of cell death GO:0060548 229 0.013
positive regulation of synapse maturation GO:0090129 2 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
ion homeostasis GO:0050801 212 0.013
embryonic pattern specification GO:0009880 1 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
gastrulation GO:0007369 2 0.013
cell morphogenesis GO:0000902 142 0.013
response to carbohydrate GO:0009743 183 0.013
macromolecule localization GO:0033036 252 0.013
p38mapk cascade GO:0038066 1 0.013
regulation of ion transport GO:0043269 245 0.013
tube formation GO:0035148 3 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.012
regulation of membrane potential GO:0042391 110 0.012
spermatogenesis GO:0007283 99 0.012
localization of cell GO:0051674 202 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of response to external stimulus GO:0032101 106 0.012
circadian rhythm GO:0007623 88 0.012
cation homeostasis GO:0055080 195 0.012
organ morphogenesis GO:0009887 75 0.012
male mating behavior GO:0060179 3 0.012
multi multicellular organism process GO:0044706 138 0.012
response to other organism GO:0051707 220 0.012
purine containing compound metabolic process GO:0072521 253 0.012
cellular amine metabolic process GO:0044106 38 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
mapk cascade GO:0000165 140 0.012
cell cycle checkpoint GO:0000075 2 0.012
aging GO:0007568 241 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
positive regulation of secretion GO:0051047 140 0.011
cellular chemical homeostasis GO:0055082 247 0.011
regulation of catalytic activity GO:0050790 304 0.011
cellular component biogenesis GO:0044085 368 0.011
positive regulation of protein modification process GO:0031401 142 0.011
establishment of protein localization GO:0045184 141 0.011
response to vitamin a GO:0033189 36 0.011
organophosphate metabolic process GO:0019637 370 0.011
regulation of behavior GO:0050795 61 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
glial cell differentiation GO:0010001 65 0.011
negative regulation of cell communication GO:0010648 158 0.011
negative regulation of stress activated mapk cascade GO:0032873 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of transmembrane transport GO:0034762 122 0.011
catabolic process GO:0009056 351 0.011
response to biotic stimulus GO:0009607 226 0.011
male gamete generation GO:0048232 99 0.011
peptide biosynthetic process GO:0043043 3 0.011
cardiac ventricle development GO:0003231 1 0.011
dna integrity checkpoint GO:0031570 2 0.011
protein heterooligomerization GO:0051291 89 0.011
ras protein signal transduction GO:0007265 29 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of phosphate metabolic process GO:0019220 349 0.010
developmental process involved in reproduction GO:0003006 159 0.010
muscle structure development GO:0061061 87 0.010
response to glucose GO:0009749 136 0.010
regulation of mapk cascade GO:0043408 116 0.010
cellular response to mechanical stimulus GO:0071260 48 0.010
regulation of response to stress GO:0080134 126 0.010
negative regulation of nervous system development GO:0051961 79 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
organic substance catabolic process GO:1901575 316 0.010
divalent inorganic cation transport GO:0072511 134 0.010
negative regulation of neuron projection development GO:0010977 46 0.010
negative regulation of jnk cascade GO:0046329 4 0.010
cell motility GO:0048870 202 0.010
gonad development GO:0008406 104 0.010

Lrfn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018