Rattus norvegicus

92 known processes

Aldh1a1

aldehyde dehydrogenase 1 family, member A1

(Aliases: Ahd2,Aldh1,Aldh2)

Aldh1a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.205
cellular amino acid metabolic process GO:0006520 107 0.155
Yeast
response to extracellular stimulus GO:0009991 380 0.132
Rat
oxoacid metabolic process GO:0043436 290 0.129
response to inorganic substance GO:0010035 377 0.103
cellular lipid metabolic process GO:0044255 208 0.099
catabolic process GO:0009056 351 0.094
Yeast
response to acid chemical GO:0001101 222 0.093
cellular catabolic process GO:0044248 295 0.086
oxidation reduction process GO:0055114 304 0.085
single organism catabolic process GO:0044712 283 0.080
carboxylic acid metabolic process GO:0019752 289 0.079
lipid metabolic process GO:0006629 283 0.077
response to nutrient levels GO:0031667 370 0.069
Rat
alpha amino acid metabolic process GO:1901605 71 0.068
single organism biosynthetic process GO:0044711 342 0.067
organic substance catabolic process GO:1901575 316 0.063
Yeast
response to toxic substance GO:0009636 133 0.060
response to metal ion GO:0010038 253 0.059
organophosphate metabolic process GO:0019637 370 0.058
Yeast
neurological system process GO:0050877 219 0.055
response to peptide GO:1901652 292 0.052
small molecule catabolic process GO:0044282 59 0.051
aging GO:0007568 241 0.045
response to nutrient GO:0007584 248 0.044
Rat
response to glucocorticoid GO:0051384 223 0.044
response to corticosteroid GO:0031960 235 0.043
amine metabolic process GO:0009308 38 0.041
Yeast
cellular response to organonitrogen compound GO:0071417 197 0.040
cellular response to endogenous stimulus GO:0071495 377 0.040
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.040
Yeast
response to peptide hormone GO:0043434 278 0.039
regulation of ion transport GO:0043269 245 0.039
cellular amine metabolic process GO:0044106 38 0.038
Yeast
regulation of molecular function GO:0065009 398 0.036
response to vitamin GO:0033273 131 0.036
Rat
transmembrane transport GO:0055085 412 0.036
response to ethanol GO:0045471 162 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
Rat
regulation of cellular component organization GO:0051128 368 0.034
response to insulin GO:0032868 133 0.034
single organism behavior GO:0044708 130 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
regulation of signal transduction GO:0009966 318 0.033
response to hypoxia GO:0001666 231 0.033
response to decreased oxygen levels GO:0036293 237 0.031
regulation of membrane potential GO:0042391 110 0.031
regulation of apoptotic process GO:0042981 335 0.031
Mouse Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
response to oxidative stress GO:0006979 186 0.030
response to transition metal nanoparticle GO:1990267 122 0.030
cellular response to peptide GO:1901653 133 0.030
reproductive process GO:0022414 372 0.030
learning or memory GO:0007611 90 0.029
intracellular signal transduction GO:0035556 314 0.029
regulation of cell differentiation GO:0045595 320 0.028
heart morphogenesis GO:0003007 3 0.028
transcription dna templated GO:0006351 377 0.028
carboxylic acid catabolic process GO:0046395 49 0.028
nitrogen compound transport GO:0071705 229 0.028
regulation of programmed cell death GO:0043067 341 0.027
Mouse Rat
synaptic transmission GO:0007268 235 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
Rat
cellular modified amino acid metabolic process GO:0006575 61 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
anion transport GO:0006820 178 0.027
ion transmembrane transport GO:0034220 365 0.026
organic acid transport GO:0015849 116 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
regulation of cell development GO:0060284 263 0.026
macromolecule localization GO:0033036 252 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
Mouse
regulation of hormone levels GO:0010817 187 0.025
programmed cell death GO:0012501 392 0.025
Mouse Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.025
apoptotic process GO:0006915 381 0.025
Mouse Rat
carbohydrate derivative metabolic process GO:1901135 346 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
rna biosynthetic process GO:0032774 380 0.024
response to oxygen levels GO:0070482 265 0.023
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.023
cation transport GO:0006812 382 0.023
chemical homeostasis GO:0048878 292 0.023
response to estrogen GO:0043627 232 0.023
cellular amide metabolic process GO:0043603 44 0.022
response to other organism GO:0051707 220 0.022
Rat
cellular response to organic cyclic compound GO:0071407 202 0.022
response to bacterium GO:0009617 200 0.022
Rat
regulation of transcription dna templated GO:0006355 374 0.022
behavior GO:0007610 205 0.022
cellular cation homeostasis GO:0030003 180 0.022
cellular response to insulin stimulus GO:0032869 81 0.022
action potential GO:0001508 54 0.021
regulation of catalytic activity GO:0050790 304 0.021
cellular homeostasis GO:0019725 252 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
Yeast
circulatory system process GO:0003013 183 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
intracellular transport GO:0046907 185 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
cell cell signaling GO:0007267 335 0.021
cellular component biogenesis GO:0044085 368 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
Yeast
cofactor metabolic process GO:0051186 95 0.021
Yeast
regulation of cell proliferation GO:0042127 359 0.021
heterocycle catabolic process GO:0046700 167 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
nucleic acid templated transcription GO:0097659 379 0.021
response to estradiol GO:0032355 164 0.020
carboxylic acid transport GO:0046942 115 0.020
negative regulation of metabolic process GO:0009892 331 0.020
glutathione metabolic process GO:0006749 15 0.020
brain development GO:0007420 247 0.020
Rat
positive regulation of cell proliferation GO:0008284 249 0.020
cellular response to lipid GO:0071396 201 0.020
Rat
cellular ketone metabolic process GO:0042180 51 0.020
organic anion transport GO:0015711 132 0.020
neuron development GO:0048666 286 0.020
fatty acid metabolic process GO:0006631 99 0.020
multicellular organismal signaling GO:0035637 44 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
ion homeostasis GO:0050801 212 0.020
regulation of rna metabolic process GO:0051252 391 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
multicellular organismal reproductive process GO:0048609 233 0.019
response to ketone GO:1901654 182 0.019
Rat
homeostatic process GO:0042592 331 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
Yeast Mouse
rna metabolic process GO:0016070 406 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
sulfur compound metabolic process GO:0006790 70 0.019
chlorinated hydrocarbon metabolic process GO:0042196 4 0.019
secretion GO:0046903 307 0.019
single organism reproductive process GO:0044702 297 0.019
multi organism reproductive process GO:0044703 262 0.019
metal ion transport GO:0030001 289 0.019
central nervous system development GO:0007417 311 0.019
Rat
response to carbohydrate GO:0009743 183 0.018
positive regulation of molecular function GO:0044093 230 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
cellular ion homeostasis GO:0006873 184 0.018
cellular component assembly GO:0022607 360 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
single organism organelle organization GO:1902589 180 0.018
regulation of phosphorylation GO:0042325 248 0.018
negative regulation of cell communication GO:0010648 158 0.018
regulation of metal ion transport GO:0010959 118 0.018
negative regulation of cell death GO:0060548 229 0.018
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
neuronal action potential GO:0019228 35 0.017
small molecule biosynthetic process GO:0044283 124 0.017
regulation of neurogenesis GO:0050767 247 0.017
organelle organization GO:0006996 266 0.017
ras protein signal transduction GO:0007265 29 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
reproduction GO:0000003 245 0.017
growth GO:0040007 165 0.017
macromolecular complex assembly GO:0065003 273 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
response to monosaccharide GO:0034284 159 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
neuron projection development GO:0031175 273 0.017
protein complex biogenesis GO:0070271 263 0.016
transmission of nerve impulse GO:0019226 42 0.016
head development GO:0060322 247 0.016
Rat
response to reactive oxygen species GO:0000302 120 0.016
response to alkaloid GO:0043279 132 0.016
Rat
regulation of secretion by cell GO:1903530 208 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
multicellular organism reproduction GO:0032504 233 0.016
phospholipid metabolic process GO:0006644 61 0.016
cellular amino acid catabolic process GO:0009063 21 0.016
positive regulation of cell death GO:0010942 184 0.016
Mouse
regulation of cellular localization GO:0060341 263 0.016
alpha amino acid biosynthetic process GO:1901607 23 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
cellular chemical homeostasis GO:0055082 247 0.016
vesicle mediated transport GO:0016192 181 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
nucleotide metabolic process GO:0009117 279 0.015
Yeast
regulation of intracellular signal transduction GO:1902531 218 0.015
negative regulation of transport GO:0051051 136 0.015
lipid catabolic process GO:0016042 46 0.015
cognition GO:0050890 92 0.015
glycerolipid metabolic process GO:0046486 67 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
organic acid biosynthetic process GO:0016053 83 0.015
cellular response to stress GO:0033554 269 0.015
regulation of system process GO:0044057 208 0.015
carbohydrate metabolic process GO:0005975 130 0.015
purine containing compound metabolic process GO:0072521 253 0.015
cation homeostasis GO:0055080 195 0.015
rhythmic process GO:0048511 156 0.015
cellular response to external stimulus GO:0071496 118 0.015
positive regulation of cell communication GO:0010647 271 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
regulation of hydrolase activity GO:0051336 143 0.014
cation transmembrane transport GO:0098655 263 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
neuron differentiation GO:0030182 368 0.014
multicellular organism growth GO:0035264 1 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
tissue development GO:0009888 252 0.014
Mouse
anion transmembrane transport GO:0098656 77 0.014
blood circulation GO:0008015 183 0.014
positive regulation of developmental process GO:0051094 283 0.014
response to radiation GO:0009314 137 0.014
chromosome segregation GO:0007059 2 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of gene expression GO:0010628 244 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
cardiac chamber development GO:0003205 1 0.014
cellular amino acid biosynthetic process GO:0008652 32 0.014
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
regulation of protein metabolic process GO:0051246 289 0.014
hormone metabolic process GO:0042445 69 0.013
regulation of neuron differentiation GO:0045664 208 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
response to cytokine GO:0034097 215 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of secretion GO:0051046 224 0.013
protein phosphorylation GO:0006468 345 0.013
response to external biotic stimulus GO:0043207 221 0.013
Rat
positive regulation of transcription dna templated GO:0045893 197 0.013
protein oligomerization GO:0051259 191 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of transport GO:0051050 245 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
regulation of blood pressure GO:0008217 83 0.013
halogenated hydrocarbon metabolic process GO:0042197 4 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
Yeast
cellular component morphogenesis GO:0032989 155 0.013
negative regulation of signaling GO:0023057 157 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
Mouse
negative regulation of programmed cell death GO:0043069 183 0.013
Rat
lipid transport GO:0006869 61 0.013
xenobiotic metabolic process GO:0006805 19 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
response to biotic stimulus GO:0009607 226 0.013
Rat
protein localization GO:0008104 191 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
regulation of nervous system development GO:0051960 264 0.013
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
organic acid catabolic process GO:0016054 49 0.012
positive regulation of signaling GO:0023056 270 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
axis specification GO:0009798 4 0.012
protein complex assembly GO:0006461 263 0.012
glycerophospholipid metabolic process GO:0006650 47 0.012
regulation of cell projection organization GO:0031344 175 0.012
muscle system process GO:0003012 115 0.012
regulation of growth GO:0040008 105 0.012
regulation of organelle organization GO:0033043 80 0.012
cellular response to xenobiotic stimulus GO:0071466 19 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
sensory perception GO:0007600 101 0.012
cytoplasmic transport GO:0016482 115 0.012
response to amino acid GO:0043200 75 0.012
response to organophosphorus GO:0046683 102 0.012
alcohol metabolic process GO:0006066 77 0.012
Yeast Mouse
heart development GO:0007507 72 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
secretion by cell GO:0032940 248 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
Rat
liver development GO:0001889 90 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
Mouse
positive regulation of secretion GO:0051047 140 0.012
developmental process involved in reproduction GO:0003006 159 0.012
glutamine family amino acid metabolic process GO:0009064 15 0.011
glutamate metabolic process GO:0006536 3 0.011
lipid oxidation GO:0034440 30 0.011
regulation of transferase activity GO:0051338 123 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of synaptic transmission GO:0050804 141 0.011
anterior posterior pattern specification GO:0009952 1 0.011
negative regulation of gene expression GO:0010629 199 0.011
cell projection organization GO:0030030 302 0.011
signal release GO:0023061 145 0.011
immune system process GO:0002376 204 0.011
divalent inorganic cation transport GO:0072511 134 0.011
gastrulation GO:0007369 2 0.011
response to vitamin e GO:0033197 24 0.011
glutamine family amino acid biosynthetic process GO:0009084 2 0.011
regulation of protein modification process GO:0031399 194 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
calcium ion transport GO:0006816 131 0.011
response to mechanical stimulus GO:0009612 134 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of ion transport GO:0043270 94 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
sex differentiation GO:0007548 113 0.011
regulation of neuron projection development GO:0010975 161 0.011
sexual reproduction GO:0019953 148 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
muscle contraction GO:0006936 88 0.011
coenzyme metabolic process GO:0006732 86 0.011
Yeast
cellular lipid catabolic process GO:0044242 37 0.011
nucleoside metabolic process GO:0009116 179 0.010
actin filament based process GO:0030029 86 0.010
circadian rhythm GO:0007623 88 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
rho protein signal transduction GO:0007266 11 0.010
cellular response to corticosteroid stimulus GO:0071384 69 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
response to lipopolysaccharide GO:0032496 191 0.010
Rat
response to wounding GO:0009611 254 0.010
cellular component movement GO:0006928 248 0.010
defense response GO:0006952 194 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
negative regulation of signal transduction GO:0009968 83 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
positive regulation of immune system process GO:0002684 90 0.010
cellular macromolecule localization GO:0070727 122 0.010
purine nucleoside metabolic process GO:0042278 169 0.010

Aldh1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.010