Rattus norvegicus

63 known processes

Aldh1a3

aldehyde dehydrogenase 1 family, member A3

(Aliases: Aldh6)

Aldh1a3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.094
Mouse Rat
programmed cell death GO:0012501 392 0.079
Mouse Rat
organic acid metabolic process GO:0006082 292 0.069
oxoacid metabolic process GO:0043436 290 0.063
positive regulation of molecular function GO:0044093 230 0.059
reproductive process GO:0022414 372 0.055
carboxylic acid metabolic process GO:0019752 289 0.053
apoptotic process GO:0006915 381 0.052
Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.052
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.050
amine metabolic process GO:0009308 38 0.049
Yeast
positive regulation of cell proliferation GO:0008284 249 0.046
cellular ketone metabolic process GO:0042180 51 0.046
response to estrogen GO:0043627 232 0.046
Rat
response to extracellular stimulus GO:0009991 380 0.045
Rat
protein phosphorylation GO:0006468 345 0.041
positive regulation of response to stimulus GO:0048584 285 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
regulation of cell proliferation GO:0042127 359 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.040
regulation of molecular function GO:0065009 398 0.040
head development GO:0060322 247 0.038
regulation of signal transduction GO:0009966 318 0.038
regulation of catalytic activity GO:0050790 304 0.038
single organism biosynthetic process GO:0044711 342 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.038
cellular amine metabolic process GO:0044106 38 0.037
Yeast
central nervous system development GO:0007417 311 0.037
response to acid chemical GO:0001101 222 0.036
Rat
cellular catabolic process GO:0044248 295 0.035
regulation of protein metabolic process GO:0051246 289 0.035
positive regulation of programmed cell death GO:0043068 157 0.035
Mouse
intracellular signal transduction GO:0035556 314 0.034
cellular response to hormone stimulus GO:0032870 247 0.034
Rat
positive regulation of developmental process GO:0051094 283 0.034
response to decreased oxygen levels GO:0036293 237 0.033
cellular response to stress GO:0033554 269 0.033
response to growth factor GO:0070848 189 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
response to metal ion GO:0010038 253 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
Rat
regulation of phosphorylation GO:0042325 248 0.032
positive regulation of signal transduction GO:0009967 175 0.032
cellular response to lipid GO:0071396 201 0.032
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
response to peptide GO:1901652 292 0.031
positive regulation of signaling GO:0023056 270 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
Yeast
positive regulation of catalytic activity GO:0043085 184 0.030
regulation of apoptotic process GO:0042981 335 0.030
Mouse Rat
response to corticosteroid GO:0031960 235 0.030
regulation of phosphate metabolic process GO:0019220 349 0.029
single organism reproductive process GO:0044702 297 0.029
regulation of protein phosphorylation GO:0001932 183 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of cellular component organization GO:0051128 368 0.028
response to nutrient levels GO:0031667 370 0.028
Rat
multicellular organismal reproductive process GO:0048609 233 0.028
regulation of cell development GO:0060284 263 0.028
response to estradiol GO:0032355 164 0.028
Rat
nucleoside metabolic process GO:0009116 179 0.028
response to hypoxia GO:0001666 231 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.027
positive regulation of cell communication GO:0010647 271 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
aging GO:0007568 241 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
organophosphate metabolic process GO:0019637 370 0.027
Yeast
response to oxygen levels GO:0070482 265 0.027
Rat
reproduction GO:0000003 245 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
regulation of canonical wnt signaling pathway GO:0060828 4 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
neuron development GO:0048666 286 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
response to inorganic substance GO:0010035 377 0.026
macromolecule localization GO:0033036 252 0.025
response to oxidative stress GO:0006979 186 0.025
Rat
signal transduction by phosphorylation GO:0023014 144 0.025
rhythmic process GO:0048511 156 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
cellular component movement GO:0006928 248 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
Mouse
multi organism reproductive process GO:0044703 262 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
response to peptide hormone GO:0043434 278 0.025
immune system process GO:0002376 204 0.025
nucleotide metabolic process GO:0009117 279 0.025
Yeast
cellular response to steroid hormone stimulus GO:0071383 93 0.024
response to insulin GO:0032868 133 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
tissue development GO:0009888 252 0.024
Mouse
organic substance catabolic process GO:1901575 316 0.024
Yeast
positive regulation of phosphorylation GO:0042327 177 0.024
proteolysis GO:0006508 175 0.024
protein oligomerization GO:0051259 191 0.023
Rat
establishment of protein localization GO:0045184 141 0.023
kidney development GO:0001822 67 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
cell type specific apoptotic process GO:0097285 134 0.023
rna biosynthetic process GO:0032774 380 0.023
positive regulation of cell death GO:0010942 184 0.023
Mouse
nucleic acid templated transcription GO:0097659 379 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
transcription dna templated GO:0006351 377 0.022
positive regulation of protein modification process GO:0031401 142 0.022
cell migration GO:0016477 197 0.022
neuron differentiation GO:0030182 368 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
cellular response to peptide GO:1901653 133 0.022
neuron apoptotic process GO:0051402 88 0.022
ras protein signal transduction GO:0007265 29 0.022
cellular component biogenesis GO:0044085 368 0.022
Rat
regulation of protein modification process GO:0031399 194 0.022
negative regulation of metabolic process GO:0009892 331 0.022
regulation of cell differentiation GO:0045595 320 0.022
regulation of hormone levels GO:0010817 187 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
inflammatory response GO:0006954 150 0.022
negative regulation of programmed cell death GO:0043069 183 0.021
Rat
glycosyl compound metabolic process GO:1901657 182 0.021
gland development GO:0048732 155 0.021
rna metabolic process GO:0016070 406 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
neuron projection development GO:0031175 273 0.021
brain development GO:0007420 247 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
regulation of hydrolase activity GO:0051336 143 0.021
regulation of nervous system development GO:0051960 264 0.021
multicellular organism reproduction GO:0032504 233 0.021
cation transport GO:0006812 382 0.021
cell projection organization GO:0030030 302 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
Yeast
negative regulation of cellular metabolic process GO:0031324 281 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
Mouse
leukocyte activation GO:0045321 76 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
cell adhesion GO:0007155 110 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
protein localization GO:0008104 191 0.020
developmental process involved in reproduction GO:0003006 159 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
mapk cascade GO:0000165 140 0.020
negative regulation of gene expression GO:0010629 199 0.019
cell activation GO:0001775 97 0.019
organelle organization GO:0006996 266 0.019
regulation of neuron projection development GO:0010975 161 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
organ morphogenesis GO:0009887 75 0.019
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of cell development GO:0010720 176 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
Yeast
purine nucleoside metabolic process GO:0042278 169 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
Rat
protein complex subunit organization GO:0071822 302 0.018
Rat
regulation of cell motility GO:2000145 131 0.018
regulation of mapk cascade GO:0043408 116 0.018
lipid metabolic process GO:0006629 283 0.018
single organism organelle organization GO:1902589 180 0.018
purine containing compound metabolic process GO:0072521 253 0.018
secretion GO:0046903 307 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
cellular lipid metabolic process GO:0044255 208 0.018
cellular response to external stimulus GO:0071496 118 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of rna metabolic process GO:0051252 391 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.017
cellular component morphogenesis GO:0032989 155 0.017
regulation of immune system process GO:0002682 123 0.017
gliogenesis GO:0042063 93 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to toxic substance GO:0009636 133 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.017
response to nutrient GO:0007584 248 0.017
Rat
positive regulation of gene expression GO:0010628 244 0.017
protein transport GO:0015031 132 0.017
renal system development GO:0072001 67 0.017
protein complex biogenesis GO:0070271 263 0.017
Rat
positive regulation of neurogenesis GO:0050769 165 0.017
chemical homeostasis GO:0048878 292 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.016
transmembrane transport GO:0055085 412 0.016
catabolic process GO:0009056 351 0.016
Yeast
axis specification GO:0009798 4 0.016
negative regulation of cell death GO:0060548 229 0.016
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
reproductive system development GO:0061458 128 0.016
cell cell signaling GO:0007267 335 0.016
regulation of locomotion GO:0040012 148 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to reactive oxygen species GO:0000302 120 0.016
localization of cell GO:0051674 202 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
neuron death GO:0070997 127 0.016
protein complex assembly GO:0006461 263 0.016
Rat
cellular component assembly GO:0022607 360 0.016
Rat
regulation of cellular localization GO:0060341 263 0.016
cell morphogenesis GO:0000902 142 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
response to ethanol GO:0045471 162 0.015
Rat
calcium ion homeostasis GO:0055074 162 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
oxidation reduction process GO:0055114 304 0.015
positive regulation of immune system process GO:0002684 90 0.015
cellular homeostasis GO:0019725 252 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
regulation of transcription dna templated GO:0006355 374 0.015
response to monosaccharide GO:0034284 159 0.015
regulation of cell projection organization GO:0031344 175 0.015
sex differentiation GO:0007548 113 0.015
regulation of system process GO:0044057 208 0.015
anterior posterior pattern specification GO:0009952 1 0.015
female pregnancy GO:0007565 122 0.014
multi multicellular organism process GO:0044706 138 0.014
response to glucocorticoid GO:0051384 223 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
peptidyl amino acid modification GO:0018193 126 0.014
reproductive structure development GO:0048608 128 0.014
growth GO:0040007 165 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
cation homeostasis GO:0055080 195 0.014
eye morphogenesis GO:0048592 4 0.014
Mouse
cellular ion homeostasis GO:0006873 184 0.014
regulation of protein kinase activity GO:0045859 105 0.014
metal ion transport GO:0030001 289 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
regulation of neuron differentiation GO:0045664 208 0.014
cell growth GO:0016049 104 0.014
response to carbohydrate GO:0009743 183 0.014
macromolecular complex assembly GO:0065003 273 0.013
Rat
cellular response to oxidative stress GO:0034599 76 0.013
defense response GO:0006952 194 0.013
heterocycle catabolic process GO:0046700 167 0.013
locomotion GO:0040011 237 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
nucleotide catabolic process GO:0009166 139 0.013
carboxylic acid transport GO:0046942 115 0.013
male gamete generation GO:0048232 99 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
organic anion transport GO:0015711 132 0.013
purine containing compound catabolic process GO:0072523 138 0.013
regulation of catabolic process GO:0009894 113 0.013
regulation of neuron death GO:1901214 115 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
urogenital system development GO:0001655 78 0.013
regulation of secretion GO:0051046 224 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
Yeast
response to glucose GO:0009749 136 0.013
circadian rhythm GO:0007623 88 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
spermatogenesis GO:0007283 99 0.013
biological adhesion GO:0022610 110 0.013
organophosphate catabolic process GO:0046434 148 0.013
regulation of secretion by cell GO:1903530 208 0.013
response to ketone GO:1901654 182 0.013
Rat
nucleoside catabolic process GO:0009164 126 0.012
gastrulation GO:0007369 2 0.012
cellular chemical homeostasis GO:0055082 247 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
membrane organization GO:0061024 94 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of cellular component movement GO:0051270 150 0.012
response to hydrogen peroxide GO:0042542 89 0.012
negative regulation of cell communication GO:0010648 158 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
response to radiation GO:0009314 137 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
regulation of transferase activity GO:0051338 123 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of nervous system development GO:0051962 178 0.012
cellular macromolecule localization GO:0070727 122 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
cell motility GO:0048870 202 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
Mouse
response to cytokine GO:0034097 215 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
secretion by cell GO:0032940 248 0.012
glycerolipid metabolic process GO:0046486 67 0.012
myeloid leukocyte activation GO:0002274 36 0.012
glycosyl compound catabolic process GO:1901658 126 0.011
regulation of protein secretion GO:0050708 28 0.011
regulation of cell migration GO:0030334 128 0.011
salivary gland development GO:0007431 3 0.011
response to wounding GO:0009611 254 0.011
cellular response to acid chemical GO:0071229 75 0.011
Rat
liver development GO:0001889 90 0.011
Rat
response to biotic stimulus GO:0009607 226 0.011
Rat
regulation of anatomical structure size GO:0090066 135 0.011
leukocyte differentiation GO:0002521 30 0.011
heart morphogenesis GO:0003007 3 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
single organism cell adhesion GO:0098602 46 0.011
aromatic compound catabolic process GO:0019439 168 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cell part morphogenesis GO:0032990 123 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
single organism intracellular transport GO:1902582 166 0.011
negative regulation of transport GO:0051051 136 0.011
immune response GO:0006955 104 0.011
bmp signaling pathway GO:0030509 4 0.011
negative regulation of developmental process GO:0051093 125 0.011
hematopoietic or lymphoid organ development GO:0048534 36 0.011
positive regulation of transferase activity GO:0051347 81 0.011
ovulation cycle GO:0042698 67 0.011
regulation of kinase activity GO:0043549 117 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
gonad development GO:0008406 104 0.011
muscle system process GO:0003012 115 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cytoplasmic transport GO:0016482 115 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
adult locomotory behavior GO:0008344 4 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of membrane potential GO:0042391 110 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
homeostatic process GO:0042592 331 0.011
intracellular transport GO:0046907 185 0.011
response to alkaloid GO:0043279 132 0.011
Rat
regulation of establishment of protein localization GO:0070201 69 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
regeneration GO:0031099 163 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
regulation of proteolysis GO:0030162 66 0.010
regulation of protein localization GO:0032880 81 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
Yeast
ion homeostasis GO:0050801 212 0.010
positive regulation of locomotion GO:0040017 102 0.010
nitrogen compound transport GO:0071705 229 0.010

Aldh1a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.018
sensory system disease DOID:0050155 0 0.011
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.011