Rattus norvegicus

20 known processes

Shank2

SH3 and multiple ankyrin repeat domains 2

(Aliases: CortBP1,Spank-3,ProSAP1)

Shank2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutamate receptor signaling pathway GO:0007215 43 0.733
Rat
intracellular signal transduction GO:0035556 314 0.614
phasic smooth muscle contraction GO:0014821 3 0.493
metal ion transport GO:0030001 289 0.394
organic substance catabolic process GO:1901575 316 0.386
regulation of ion transport GO:0043269 245 0.365
second messenger mediated signaling GO:0019932 51 0.353
heterocycle catabolic process GO:0046700 167 0.328
behavior GO:0007610 205 0.328
Human Mouse Worm
reproductive process GO:0022414 372 0.311
calcium mediated signaling GO:0019722 23 0.273
cellular catabolic process GO:0044248 295 0.264
positive regulation of synaptic transmission GO:0050806 62 0.254
Mouse
purine nucleotide metabolic process GO:0006163 229 0.243
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 2 0.242
regulation of cellular component organization GO:0051128 368 0.240
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.220
brain development GO:0007420 247 0.216
protein complex subunit organization GO:0071822 302 0.197
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.197
Rat
cell motility GO:0048870 202 0.194
catabolic process GO:0009056 351 0.189
regulation of system process GO:0044057 208 0.186
regulation of cellular protein metabolic process GO:0032268 267 0.185
muscle contraction GO:0006936 88 0.183
cellular response to organic cyclic compound GO:0071407 202 0.178
tissue development GO:0009888 252 0.178
purine nucleotide catabolic process GO:0006195 136 0.177
cellular chemical homeostasis GO:0055082 247 0.176
nucleobase containing small molecule metabolic process GO:0055086 316 0.173
head development GO:0060322 247 0.171
aromatic compound catabolic process GO:0019439 168 0.170
nucleotide metabolic process GO:0009117 279 0.170
nucleotide catabolic process GO:0009166 139 0.161
cell adhesion GO:0007155 110 0.161
central nervous system development GO:0007417 311 0.160
response to alkaloid GO:0043279 132 0.160
organophosphate metabolic process GO:0019637 370 0.157
localization of cell GO:0051674 202 0.157
cation transport GO:0006812 382 0.156
regulation of molecular function GO:0065009 398 0.153
cellular homeostasis GO:0019725 252 0.152
cellular cation homeostasis GO:0030003 180 0.150
cell migration GO:0016477 197 0.150
cellular ion homeostasis GO:0006873 184 0.149
regulation of cellular catabolic process GO:0031329 101 0.147
transmembrane transport GO:0055085 412 0.146
positive regulation of cell migration GO:0030335 96 0.144
regulation of synaptic transmission GO:0050804 141 0.143
Mouse
purine ribonucleotide catabolic process GO:0009154 136 0.140
programmed cell death GO:0012501 392 0.138
metal ion homeostasis GO:0055065 186 0.136
cellular metal ion homeostasis GO:0006875 172 0.135
cellular response to corticosteroid stimulus GO:0071384 69 0.135
positive regulation of cellular component organization GO:0051130 200 0.134
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.133
chemical homeostasis GO:0048878 292 0.133
actin filament based process GO:0030029 86 0.133
positive regulation of hydrolase activity GO:0051345 86 0.132
cellular component biogenesis GO:0044085 368 0.130
Mouse Rat
regulation of nervous system development GO:0051960 264 0.128
Rat
macromolecular complex subunit organization GO:0043933 339 0.125
Rat
cation homeostasis GO:0055080 195 0.123
rna metabolic process GO:0016070 406 0.123
inflammatory response to antigenic stimulus GO:0002437 18 0.120
purine containing compound metabolic process GO:0072521 253 0.119
locomotion GO:0040011 237 0.118
peristalsis GO:0030432 2 0.116
organonitrogen compound catabolic process GO:1901565 179 0.115
muscle system process GO:0003012 115 0.114
purine containing compound catabolic process GO:0072523 138 0.113
apoptotic process GO:0006915 381 0.113
regulation of postsynaptic membrane potential GO:0060078 25 0.112
purine nucleoside catabolic process GO:0006152 124 0.111
neurological system process GO:0050877 219 0.110
Human Mouse
regulation of catalytic activity GO:0050790 304 0.108
regulation of programmed cell death GO:0043067 341 0.106
regulation of hydrolase activity GO:0051336 143 0.106
cellular response to glucocorticoid stimulus GO:0071385 68 0.105
positive regulation of phosphate metabolic process GO:0045937 262 0.105
positive regulation of molecular function GO:0044093 230 0.105
organelle organization GO:0006996 266 0.105
cellular divalent inorganic cation homeostasis GO:0072503 162 0.104
regulation of apoptotic process GO:0042981 335 0.100
ribose phosphate metabolic process GO:0019693 235 0.100
positive regulation of catalytic activity GO:0043085 184 0.100
neuron development GO:0048666 286 0.099
Rat
positive regulation of response to stimulus GO:0048584 285 0.099
Rat
response to nutrient levels GO:0031667 370 0.098
cytoskeleton organization GO:0007010 111 0.098
cellular component assembly GO:0022607 360 0.098
Mouse Rat
positive regulation of locomotion GO:0040017 102 0.098
cell projection organization GO:0030030 302 0.097
Rat
divalent inorganic cation transport GO:0072511 134 0.097
cellular nitrogen compound catabolic process GO:0044270 163 0.096
nucleoside phosphate metabolic process GO:0006753 283 0.094
regulation of purine nucleotide catabolic process GO:0033121 65 0.094
cellular response to oxygen containing compound GO:1901701 386 0.092
nucleoside phosphate catabolic process GO:1901292 140 0.090
regulation of intracellular signal transduction GO:1902531 218 0.090
nucleoside triphosphate catabolic process GO:0009143 123 0.089
regulation of sensory perception of pain GO:0051930 29 0.089
regulation of metal ion transport GO:0010959 118 0.088
negative regulation of cell death GO:0060548 229 0.088
g protein coupled receptor signaling pathway GO:0007186 242 0.087
divalent inorganic cation homeostasis GO:0072507 165 0.086
nucleic acid templated transcription GO:0097659 379 0.085
response to starvation GO:0042594 59 0.085
cellular response to hormone stimulus GO:0032870 247 0.085
regulation of blood circulation GO:1903522 110 0.084
signal transduction by phosphorylation GO:0023014 144 0.083
ribonucleoside triphosphate metabolic process GO:0009199 141 0.083
heart contraction GO:0060047 57 0.083
rhythmic process GO:0048511 156 0.083
Worm
cellular component movement GO:0006928 248 0.081
cell projection morphogenesis GO:0048858 123 0.080
ribonucleoside triphosphate catabolic process GO:0009203 122 0.079
synapse assembly GO:0007416 29 0.078
Mouse
cellular response to nitrogen compound GO:1901699 210 0.078
somatostatin receptor signaling pathway GO:0038169 4 0.077
negative regulation of apoptotic process GO:0043066 181 0.077
positive regulation of cell motility GO:2000147 97 0.076
regulation of ion transmembrane transporter activity GO:0032412 48 0.075
single organism catabolic process GO:0044712 283 0.075
neuropeptide signaling pathway GO:0007218 29 0.075
amine metabolic process GO:0009308 38 0.075
cellular response to alcohol GO:0097306 87 0.074
glycosyl compound metabolic process GO:1901657 182 0.074
single organism behavior GO:0044708 130 0.073
Human Mouse
negative regulation of programmed cell death GO:0043069 183 0.073
positive regulation of gtp catabolic process GO:0033126 48 0.073
carbohydrate derivative catabolic process GO:1901136 147 0.072
cytosolic calcium ion homeostasis GO:0051480 140 0.072
regulation of nucleotide metabolic process GO:0006140 117 0.072
transcription dna templated GO:0006351 377 0.072
forebrain development GO:0030900 98 0.072
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.071
regulation of response to external stimulus GO:0032101 106 0.071
inflammatory response GO:0006954 150 0.069
ion homeostasis GO:0050801 212 0.069
positive regulation of phosphorus metabolic process GO:0010562 262 0.069
cell morphogenesis GO:0000902 142 0.068
single organism organelle organization GO:1902589 180 0.067
positive regulation of programmed cell death GO:0043068 157 0.067
hormone mediated signaling pathway GO:0009755 23 0.066
cellular response to ammonium ion GO:0071242 17 0.066
protein localization GO:0008104 191 0.065
regulation of actin filament bundle assembly GO:0032231 13 0.065
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.065
regulation of muscle contraction GO:0006937 53 0.064
organic cyclic compound catabolic process GO:1901361 175 0.064
intracellular transport GO:0046907 185 0.063
neuron differentiation GO:0030182 368 0.063
Rat
cell cell signaling GO:0007267 335 0.062
Mouse
regulation of protein metabolic process GO:0051246 289 0.062
regulation of neurogenesis GO:0050767 247 0.061
Rat
positive regulation of apoptotic process GO:0043065 154 0.061
regulation of cellular component movement GO:0051270 150 0.061
homeostatic process GO:0042592 331 0.061
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.060
regulation of actin filament based process GO:0032970 42 0.060
ion transmembrane transport GO:0034220 365 0.060
nucleobase containing compound catabolic process GO:0034655 152 0.060
regulation of cell differentiation GO:0045595 320 0.060
Rat
ribonucleotide metabolic process GO:0009259 231 0.060
cellular amine metabolic process GO:0044106 38 0.060
synaptic transmission GO:0007268 235 0.059
Mouse
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.059
purine nucleoside metabolic process GO:0042278 169 0.059
ribonucleoside metabolic process GO:0009119 174 0.058
cellular amino acid metabolic process GO:0006520 107 0.057
guanosine containing compound catabolic process GO:1901069 71 0.057
circulatory system process GO:0003013 183 0.057
immune system process GO:0002376 204 0.057
defense response GO:0006952 194 0.056
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.056
sensory perception GO:0007600 101 0.056
multicellular organism reproduction GO:0032504 233 0.056
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.056
developmental growth GO:0048589 100 0.055
regulation of purine nucleotide metabolic process GO:1900542 115 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
regulation of signal transduction GO:0009966 318 0.054
Rat
growth GO:0040007 165 0.054
regulation of cellular component biogenesis GO:0044087 86 0.053
regulation of neuron projection development GO:0010975 161 0.053
Rat
regulation of multicellular organismal development GO:2000026 376 0.053
Rat
ribonucleotide catabolic process GO:0009261 136 0.052
carboxylic acid metabolic process GO:0019752 289 0.052
positive regulation of signaling GO:0023056 270 0.052
Mouse Rat
positive regulation of gtpase activity GO:0043547 47 0.052
organophosphate catabolic process GO:0046434 148 0.052
secretion by cell GO:0032940 248 0.052
regulation of response to nutrient levels GO:0032107 11 0.052
regulation of gtpase activity GO:0043087 57 0.051
response to glucocorticoid GO:0051384 223 0.051
cellular calcium ion homeostasis GO:0006874 160 0.051
purine ribonucleoside metabolic process GO:0046128 168 0.051
positive regulation of cytoskeleton organization GO:0051495 26 0.050
positive regulation of cellular component movement GO:0051272 102 0.050
nucleoside triphosphate metabolic process GO:0009141 144 0.050
camp metabolic process GO:0046058 63 0.050
single organism biosynthetic process GO:0044711 342 0.049
response to ethanol GO:0045471 162 0.049
positive regulation of transport GO:0051050 245 0.049
regulation of cell development GO:0060284 263 0.049
Rat
cation transmembrane transport GO:0098655 263 0.049
cellular response to lipid GO:0071396 201 0.048
regulation of anatomical structure size GO:0090066 135 0.048
regulation of locomotion GO:0040012 148 0.048
nucleoside catabolic process GO:0009164 126 0.048
regulation of catabolic process GO:0009894 113 0.048
regulation of cytoskeleton organization GO:0051493 49 0.048
regulation of actin cytoskeleton organization GO:0032956 30 0.048
positive regulation of signal transduction GO:0009967 175 0.047
Rat
macromolecule localization GO:0033036 252 0.047
inorganic ion transmembrane transport GO:0098660 229 0.047
guanosine containing compound metabolic process GO:1901068 74 0.047
macromolecular complex assembly GO:0065003 273 0.046
Rat
calcium ion transport GO:0006816 131 0.046
actin cytoskeleton organization GO:0030036 73 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.046
regulation of tube size GO:0035150 89 0.046
positive regulation of response to external stimulus GO:0032103 51 0.046
response to ketone GO:1901654 182 0.046
synaptic growth at neuromuscular junction GO:0051124 1 0.045
anatomical structure morphogenesis GO:0009653 298 0.045
positive regulation of secretion GO:0051047 140 0.045
positive regulation of cellular catabolic process GO:0031331 71 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
protein complex biogenesis GO:0070271 263 0.044
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.043
neuron projection development GO:0031175 273 0.043
Rat
aging GO:0007568 241 0.043
response to corticosteroid GO:0031960 235 0.043
response to hypoxia GO:0001666 231 0.042
positive regulation of nucleotide catabolic process GO:0030813 53 0.042
anion transport GO:0006820 178 0.041
positive regulation of neuron projection development GO:0010976 99 0.041
Rat
oxoacid metabolic process GO:0043436 290 0.041
regulation of nucleotide catabolic process GO:0030811 65 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.041
purine nucleotide biosynthetic process GO:0006164 83 0.041
calcium ion homeostasis GO:0055074 162 0.041
regulation of muscle system process GO:0090257 79 0.040
positive regulation of developmental process GO:0051094 283 0.040
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.040
positive regulation of cell communication GO:0010647 271 0.040
Mouse Rat
regulation of cellular amine metabolic process GO:0033238 8 0.040
neuron projection morphogenesis GO:0048812 122 0.039
synapse organization GO:0050808 46 0.039
Mouse Rat
positive regulation of gene expression GO:0010628 244 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.038
cell growth GO:0016049 104 0.038
cellular response to endogenous stimulus GO:0071495 377 0.038
regulation of receptor activity GO:0010469 29 0.038
sensory perception of pain GO:0019233 73 0.038
regulation of membrane potential GO:0042391 110 0.037
regulation of dendrite development GO:0050773 59 0.037
Rat
phospholipid metabolic process GO:0006644 61 0.037
carbohydrate metabolic process GO:0005975 130 0.037
positive regulation of protein metabolic process GO:0051247 178 0.037
positive regulation of nucleoside metabolic process GO:0045979 55 0.037
cellular macromolecule catabolic process GO:0044265 29 0.037
negative regulation of cell proliferation GO:0008285 119 0.037
regulation of calcium ion transport GO:0051924 77 0.036
gtp catabolic process GO:0006184 71 0.036
regulation of cell migration GO:0030334 128 0.036
mapk cascade GO:0000165 140 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.036
negative regulation of metabolic process GO:0009892 331 0.036
positive regulation of nucleic acid templated transcription GO:1903508 197 0.036
response to oxygen levels GO:0070482 265 0.035
regulation of cell morphogenesis GO:0022604 77 0.035
ribonucleotide biosynthetic process GO:0009260 85 0.035
nucleoside metabolic process GO:0009116 179 0.035
regulation of protein kinase activity GO:0045859 105 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.035
wound healing GO:0042060 122 0.034
purine containing compound biosynthetic process GO:0072522 85 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
regulation of transferase activity GO:0051338 123 0.034
negative regulation of phosphate metabolic process GO:0045936 80 0.034
acute inflammatory response GO:0002526 58 0.034
organophosphate biosynthetic process GO:0090407 143 0.033
regulation of neuron differentiation GO:0045664 208 0.033
Rat
signal release GO:0023061 145 0.033
macromolecule catabolic process GO:0009057 58 0.033
ribonucleoside catabolic process GO:0042454 126 0.033
positive regulation of protein modification process GO:0031401 142 0.033
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 6 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
positive regulation of cell projection organization GO:0031346 111 0.033
Rat
anterior posterior pattern specification GO:0009952 1 0.033
small gtpase mediated signal transduction GO:0007264 36 0.033
endocytosis GO:0006897 84 0.032
cellular ketone metabolic process GO:0042180 51 0.032
negative regulation of ion transport GO:0043271 51 0.032
regulation of proteasomal protein catabolic process GO:0061136 4 0.032
positive regulation of phosphorylation GO:0042327 177 0.032
positive regulation of neuron differentiation GO:0045666 126 0.032
Rat
positive regulation of cellular component biogenesis GO:0044089 55 0.031
response to estradiol GO:0032355 164 0.031
regulation of glutamate receptor signaling pathway GO:1900449 17 0.031
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
regulation of sensory perception GO:0051931 29 0.030
regulation of secretion GO:0051046 224 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
regulation of cellular localization GO:0060341 263 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
vascular process in circulatory system GO:0003018 96 0.030
positive regulation of transferase activity GO:0051347 81 0.030
b cell differentiation GO:0030183 2 0.029
regulation of cell motility GO:2000145 131 0.029
response to extracellular stimulus GO:0009991 380 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
actomyosin structure organization GO:0031032 22 0.029
regulation of rna metabolic process GO:0051252 391 0.028
heart process GO:0003015 57 0.028
rho protein signal transduction GO:0007266 11 0.028
response to carbohydrate GO:0009743 183 0.028
multicellular organism growth GO:0035264 1 0.028
response to nutrient GO:0007584 248 0.028
positive regulation of secretion by cell GO:1903532 128 0.028
activation of phospholipase d activity GO:0031584 2 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
cellular response to steroid hormone stimulus GO:0071383 93 0.028
regulation of response to food GO:0032095 11 0.027
rna biosynthetic process GO:0032774 380 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
vesicle mediated transport GO:0016192 181 0.027
inorganic cation transmembrane transport GO:0098662 202 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
gtp metabolic process GO:0046039 72 0.027
membrane depolarization GO:0051899 32 0.027
positive regulation of organelle organization GO:0010638 48 0.026
regulation of protein modification process GO:0031399 194 0.026
hematopoietic progenitor cell differentiation GO:0002244 2 0.026
protein complex assembly GO:0006461 263 0.026
Rat
biological adhesion GO:0022610 110 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
glycosyl compound catabolic process GO:1901658 126 0.026
divalent metal ion transport GO:0070838 132 0.025
negative regulation of camp biosynthetic process GO:0030818 12 0.025
muscle cell proliferation GO:0033002 84 0.025
cytoplasmic transport GO:0016482 115 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.025
hormone secretion GO:0046879 115 0.025
central nervous system neuron axonogenesis GO:0021955 1 0.024
memory GO:0007613 54 0.024
Mouse
regulation of gtp catabolic process GO:0033124 58 0.024
protein oligomerization GO:0051259 191 0.024
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.024
negative regulation of adenylate cyclase activity GO:0007194 7 0.024
positive regulation of nucleotide metabolic process GO:0045981 91 0.024
ras protein signal transduction GO:0007265 29 0.023
epithelium development GO:0060429 96 0.023
regulation of blood pressure GO:0008217 83 0.023
regulation of developmental growth GO:0048638 45 0.023
ribose phosphate biosynthetic process GO:0046390 87 0.023
positive regulation of hormone secretion GO:0046887 65 0.023
actin filament organization GO:0007015 42 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
positive regulation of kinase activity GO:0033674 77 0.023
smooth muscle cell migration GO:0014909 36 0.023
response to decreased oxygen levels GO:0036293 237 0.023
protein phosphorylation GO:0006468 345 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.022
regulation of synapse organization GO:0050807 19 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
regulation of lyase activity GO:0051339 22 0.022
positive regulation of cell development GO:0010720 176 0.022
Rat
positive regulation of dendritic spine development GO:0060999 9 0.022
Rat
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.022
hormone transport GO:0009914 121 0.022
blood circulation GO:0008015 183 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
response to cocaine GO:0042220 39 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.021
actin filament based movement GO:0030048 16 0.021
regulation of camp metabolic process GO:0030814 43 0.021
regulation of nucleoside metabolic process GO:0009118 66 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
regulation of phosphorylation GO:0042325 248 0.021
multi organism reproductive process GO:0044703 262 0.021
neuron neuron synaptic transmission GO:0007270 60 0.021
regulation of growth GO:0040008 105 0.021
lipid modification GO:0030258 52 0.020
nucleotide biosynthetic process GO:0009165 98 0.020
sexual reproduction GO:0019953 148 0.020
cellular protein localization GO:0034613 122 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
activation of mapkk activity GO:0000186 18 0.020
immune response GO:0006955 104 0.020
single organism reproductive process GO:0044702 297 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
smooth muscle contraction GO:0006939 37 0.020
organic acid metabolic process GO:0006082 292 0.020
positive regulation of cell death GO:0010942 184 0.020
regulation of adenylate cyclase activity GO:0045761 18 0.019
regulation of mapk cascade GO:0043408 116 0.019
reactive oxygen species metabolic process GO:0072593 37 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
response to acid chemical GO:0001101 222 0.019
response to hexose GO:0009746 144 0.019
cyclic purine nucleotide metabolic process GO:0052652 62 0.019
sequestering of calcium ion GO:0051208 8 0.019
actin filament bundle assembly GO:0051017 19 0.019
response to temperature stimulus GO:0009266 94 0.019
action potential GO:0001508 54 0.019
defecation GO:0030421 1 0.018
Worm
coenzyme metabolic process GO:0006732 86 0.018
protein catabolic process GO:0030163 30 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.018
regulation of cell proliferation GO:0042127 359 0.018
calcium ion import GO:0070509 22 0.018
peptide secretion GO:0002790 86 0.018
long term synaptic potentiation GO:0060291 21 0.018
Mouse
alcohol metabolic process GO:0006066 77 0.018
positive regulation of ion transport GO:0043270 94 0.018
axon development GO:0061564 96 0.018
response to wounding GO:0009611 254 0.018
dendritic spine morphogenesis GO:0060997 9 0.018
response to growth factor GO:0070848 189 0.017
response to isoquinoline alkaloid GO:0014072 28 0.017
regulation of cyclase activity GO:0031279 21 0.017
sequestering of metal ion GO:0051238 9 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
neurotransmitter gated ion channel clustering GO:0072578 3 0.017
lipid metabolic process GO:0006629 283 0.017
regulation of blood vessel size GO:0050880 89 0.017
regulation of cellular response to stress GO:0080135 49 0.017
atp metabolic process GO:0046034 72 0.017
positive regulation of ras gtpase activity GO:0032320 28 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
regulation of defense response GO:0031347 68 0.017
circadian rhythm GO:0007623 88 0.017
single organism intracellular transport GO:1902582 166 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
regulation of heart contraction GO:0008016 48 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.016
response to morphine GO:0043278 27 0.016
response to monosaccharide GO:0034284 159 0.016
cell activation GO:0001775 97 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
maintenance of location GO:0051235 17 0.016
camp biosynthetic process GO:0006171 47 0.016
regulation of kinase activity GO:0043549 117 0.016
carboxylic acid transport GO:0046942 115 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
peptide transport GO:0015833 97 0.016
regulation of immune response GO:0050776 55 0.016
cardiac muscle contraction GO:0060048 27 0.016
positive regulation of catabolic process GO:0009896 78 0.016
response to ammonium ion GO:0060359 71 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
developmental growth involved in morphogenesis GO:0060560 33 0.015
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.015
cellular component morphogenesis GO:0032989 155 0.015
regulation of response to stress GO:0080134 126 0.015
carbohydrate homeostasis GO:0033500 75 0.015
regulation of response to wounding GO:1903034 69 0.015
muscle cell migration GO:0014812 36 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
calcium ion transport into cytosol GO:0060402 38 0.015
regulation of organelle organization GO:0033043 80 0.015
chemotaxis GO:0006935 66 0.015
membrane organization GO:0061024 94 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
spermatogenesis GO:0007283 99 0.015
positive regulation of nervous system development GO:0051962 178 0.015
Rat
cellular lipid metabolic process GO:0044255 208 0.015
regulation of amine transport GO:0051952 54 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
regulation of camp biosynthetic process GO:0030817 38 0.015
positive regulation of mapk cascade GO:0043410 92 0.014
excretion GO:0007588 24 0.014
Worm

Shank2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
organ system cancer DOID:0050686 0 0.031
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.017
bone disease DOID:0080001 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015