Rattus norvegicus

65 known processes

Shank1

SH3 and multiple ankyrin repeat domains 1

(Aliases: Sstrip,Spank1,Shank1a)

Shank1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutamate receptor signaling pathway GO:0007215 43 0.896
Mouse Rat
transmembrane transport GO:0055085 412 0.530
Mouse
cellular homeostasis GO:0019725 252 0.508
positive regulation of membrane potential GO:0045838 16 0.479
Mouse
ion transmembrane transport GO:0034220 365 0.477
Mouse
regulation of glutamate receptor signaling pathway GO:1900449 17 0.419
Mouse Rat
behavior GO:0007610 205 0.393
Human Mouse Worm
regulation of synaptic transmission GO:0050804 141 0.359
organic anion transport GO:0015711 132 0.350
synaptic growth at neuromuscular junction GO:0051124 1 0.332
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 6 0.327
single organism behavior GO:0044708 130 0.316
Human Mouse
regulation of postsynaptic membrane potential GO:0060078 25 0.309
Mouse
neuronal ion channel clustering GO:0045161 3 0.296
cell cell signaling GO:0007267 335 0.290
Mouse
neuropeptide signaling pathway GO:0007218 29 0.288
protein complex subunit organization GO:0071822 302 0.265
neurological system process GO:0050877 219 0.254
Human Mouse
regulation of molecular function GO:0065009 398 0.249
Mouse
rhythmic process GO:0048511 156 0.245
Worm
sensory perception GO:0007600 101 0.230
Human
neuron differentiation GO:0030182 368 0.225
positive regulation of multicellular organismal process GO:0051240 387 0.205
amino acid transport GO:0006865 70 0.202
neuromuscular process GO:0050905 2 0.190
Mouse
exploration behavior GO:0035640 1 0.185
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.180
metal ion transport GO:0030001 289 0.173
positive regulation of cell communication GO:0010647 271 0.157
Rat
regulation of behavior GO:0050795 61 0.153
macromolecule localization GO:0033036 252 0.150
Mouse
protein complex biogenesis GO:0070271 263 0.150
axon development GO:0061564 96 0.146
receptor localization to synapse GO:0097120 2 0.142
mapk cascade GO:0000165 140 0.142
asymmetric protein localization GO:0008105 2 0.142
urinary bladder smooth muscle contraction GO:0014832 4 0.141
catabolic process GO:0009056 351 0.139
cellular ion homeostasis GO:0006873 184 0.138
regulation of neuron differentiation GO:0045664 208 0.137
postsynaptic membrane organization GO:0001941 5 0.133
inorganic ion transmembrane transport GO:0098660 229 0.133
carbohydrate derivative catabolic process GO:1901136 147 0.133
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.131
protein complex assembly GO:0006461 263 0.131
endocytosis GO:0006897 84 0.129
regulation of signal transduction GO:0009966 318 0.128
Mouse Rat
macromolecular complex subunit organization GO:0043933 339 0.127
receptor clustering GO:0043113 13 0.124
calcium ion dependent exocytosis of neurotransmitter GO:0048791 2 0.123
receptor internalization GO:0031623 14 0.121
metal ion homeostasis GO:0055065 186 0.120
regulation of multicellular organismal development GO:2000026 376 0.118
cation transport GO:0006812 382 0.117
regulation of cell differentiation GO:0045595 320 0.115
limbic system development GO:0021761 38 0.114
regulation of cellular component organization GO:0051128 368 0.114
ion homeostasis GO:0050801 212 0.114
chemical homeostasis GO:0048878 292 0.112
calcium ion homeostasis GO:0055074 162 0.111
regulation of membrane potential GO:0042391 110 0.105
Mouse
cellular metal ion homeostasis GO:0006875 172 0.103
signal transduction by phosphorylation GO:0023014 144 0.103
adult locomotory behavior GO:0008344 4 0.100
cellular chemical homeostasis GO:0055082 247 0.096
positive regulation of molecular function GO:0044093 230 0.093
cation transmembrane transport GO:0098655 263 0.091
cellular calcium ion homeostasis GO:0006874 160 0.091
organonitrogen compound catabolic process GO:1901565 179 0.089
positive regulation of long term synaptic potentiation GO:1900273 4 0.087
cell morphogenesis involved in differentiation GO:0000904 119 0.087
Mouse
aromatic compound catabolic process GO:0019439 168 0.085
organic acid transport GO:0015849 116 0.085
regulation of ion transport GO:0043269 245 0.085
Mouse
regulation of cell development GO:0060284 263 0.083
intracellular signal transduction GO:0035556 314 0.083
regulation of neurogenesis GO:0050767 247 0.082
organelle organization GO:0006996 266 0.082
Mouse
organophosphate metabolic process GO:0019637 370 0.082
regulation of transmembrane transporter activity GO:0022898 49 0.081
Mouse
gland development GO:0048732 155 0.081
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.080
Mouse
potassium ion transport GO:0006813 97 0.079
axonogenesis GO:0007409 71 0.079
synaptic transmission GO:0007268 235 0.078
Mouse
cellular component assembly GO:0022607 360 0.078
divalent inorganic cation homeostasis GO:0072507 165 0.076
cellular catabolic process GO:0044248 295 0.075
inorganic cation transmembrane transport GO:0098662 202 0.075
locomotory exploration behavior GO:0035641 1 0.075
actin filament based process GO:0030029 86 0.074
Mouse
grooming behavior GO:0007625 4 0.074
neuron neuron synaptic transmission GO:0007270 60 0.072
response to radiation GO:0009314 137 0.071
positive regulation of ion transport GO:0043270 94 0.071
defecation GO:0030421 1 0.071
Worm
homeostatic process GO:0042592 331 0.070
response to nutrient GO:0007584 248 0.070
Rat
central nervous system development GO:0007417 311 0.070
Rat
regulation of catalytic activity GO:0050790 304 0.069
anion transport GO:0006820 178 0.069
response to alkaloid GO:0043279 132 0.069
regulation of phosphorylation GO:0042325 248 0.069
negative regulation of signaling GO:0023057 157 0.069
carbohydrate derivative metabolic process GO:1901135 346 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.067
oxoacid metabolic process GO:0043436 290 0.067
cytoskeleton organization GO:0007010 111 0.067
Mouse
regulation of nervous system development GO:0051960 264 0.066
organic substance catabolic process GO:1901575 316 0.066
response to ethanol GO:0045471 162 0.065
regulation of ion transmembrane transport GO:0034765 121 0.065
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.064
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.064
carboxylic acid transport GO:0046942 115 0.064
regulation of neuronal synaptic plasticity GO:0048168 31 0.063
anatomical structure morphogenesis GO:0009653 298 0.063
Mouse
camp metabolic process GO:0046058 63 0.062
negative regulation of nervous system development GO:0051961 79 0.061
olfactory behavior GO:0042048 2 0.061
Mouse
positive regulation of developmental process GO:0051094 283 0.061
response to mechanical stimulus GO:0009612 134 0.060
neurotransmitter gated ion channel clustering GO:0072578 3 0.060
olfactory learning GO:0008355 1 0.059
cellular component morphogenesis GO:0032989 155 0.059
Mouse
positive regulation of programmed cell death GO:0043068 157 0.059
regulation of synaptic transmission glutamatergic GO:0051966 26 0.058
regulation of synapse assembly GO:0051963 15 0.058
head development GO:0060322 247 0.058
Rat
regulation of synaptic plasticity GO:0048167 70 0.057
multi organism reproductive process GO:0044703 262 0.056
positive regulation of catalytic activity GO:0043085 184 0.056
negative regulation of cell communication GO:0010648 158 0.056
receptor metabolic process GO:0043112 18 0.056
response to oxidative stress GO:0006979 186 0.056
cellular divalent inorganic cation homeostasis GO:0072503 162 0.056
secretion by cell GO:0032940 248 0.056
sexual reproduction GO:0019953 148 0.055
synapse assembly GO:0007416 29 0.054
positive regulation of cellular component organization GO:0051130 200 0.054
cellular response to oxygen containing compound GO:1901701 386 0.053
regulation of cellular component biogenesis GO:0044087 86 0.053
Mouse
negative regulation of phosphorus metabolic process GO:0010563 80 0.053
regulation of blood circulation GO:1903522 110 0.052
regulation of neuron projection development GO:0010975 161 0.052
positive regulation of synaptic transmission GO:0050806 62 0.051
telencephalon development GO:0021537 62 0.051
smooth muscle contraction GO:0006939 37 0.050
regulation of transmembrane transport GO:0034762 122 0.050
Mouse
response to extracellular stimulus GO:0009991 380 0.050
Rat
cellular cation homeostasis GO:0030003 180 0.050
neuron projection morphogenesis GO:0048812 122 0.049
Mouse
rhythmic behavior GO:0007622 24 0.049
Worm
cellular response to organic cyclic compound GO:0071407 202 0.049
response to estradiol GO:0032355 164 0.048
negative regulation of camp metabolic process GO:0030815 14 0.048
locomotion GO:0040011 237 0.048
nucleotide metabolic process GO:0009117 279 0.047
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.047
cytosolic calcium ion homeostasis GO:0051480 140 0.047
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.046
Mouse
neuron development GO:0048666 286 0.046
nucleobase containing small molecule metabolic process GO:0055086 316 0.046
response to retinoic acid GO:0032526 63 0.046
regulation of synapse organization GO:0050807 19 0.046
positive regulation of cellular component biogenesis GO:0044089 55 0.045
protein localization to membrane GO:0072657 36 0.045
camp biosynthetic process GO:0006171 47 0.045
regulation of ion transmembrane transporter activity GO:0032412 48 0.045
Mouse
regulation of endocrine process GO:0044060 21 0.045
locomotory behavior GO:0007626 15 0.045
response to light stimulus GO:0009416 52 0.045
regulation of system process GO:0044057 208 0.044
membrane organization GO:0061024 94 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
positive regulation of synapse assembly GO:0051965 12 0.044
synapse organization GO:0050808 46 0.043
organophosphate biosynthetic process GO:0090407 143 0.043
positive regulation of cell development GO:0010720 176 0.043
dendritic spine morphogenesis GO:0060997 9 0.043
Mouse
cell projection organization GO:0030030 302 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.043
multicellular organism reproduction GO:0032504 233 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
purine ribonucleoside metabolic process GO:0046128 168 0.042
cellular response to nitrogen compound GO:1901699 210 0.042
regulation of cellular protein metabolic process GO:0032268 267 0.042
organic acid metabolic process GO:0006082 292 0.042
response to histamine GO:0034776 3 0.042
positive regulation of protein modification process GO:0031401 142 0.041
urinary tract smooth muscle contraction GO:0014848 4 0.040
response to peptide GO:1901652 292 0.040
associative learning GO:0008306 19 0.040
Mouse
cellular protein localization GO:0034613 122 0.040
hippocampus development GO:0021766 30 0.039
nucleoside phosphate metabolic process GO:0006753 283 0.039
apoptotic process GO:0006915 381 0.038
cellular lipid metabolic process GO:0044255 208 0.038
response to peptide hormone GO:0043434 278 0.037
signal release GO:0023061 145 0.037
ribonucleotide metabolic process GO:0009259 231 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
cellular macromolecule localization GO:0070727 122 0.036
negative regulation of response to stimulus GO:0048585 155 0.036
negative regulation of luteinizing hormone secretion GO:0033685 4 0.036
regulation of potassium ion transport GO:0043266 29 0.036
lipid metabolic process GO:0006629 283 0.036
chemosensory behavior GO:0007635 2 0.036
Mouse
cellular nitrogen compound catabolic process GO:0044270 163 0.036
negative regulation of dopamine secretion GO:0033602 4 0.036
purine nucleotide metabolic process GO:0006163 229 0.036
purine nucleoside metabolic process GO:0042278 169 0.036
heterocycle catabolic process GO:0046700 167 0.035
reproductive process GO:0022414 372 0.035
cardiac chamber development GO:0003205 1 0.035
neuron projection development GO:0031175 273 0.035
heart morphogenesis GO:0003007 3 0.035
response to fungicide GO:0060992 20 0.034
regulation of nucleotide metabolic process GO:0006140 117 0.034
vesicle mediated transport GO:0016192 181 0.034
negative regulation of metabolic process GO:0009892 331 0.034
regulation of purine nucleotide metabolic process GO:1900542 115 0.034
regulation of vesicle mediated transport GO:0060627 81 0.034
cellular component biogenesis GO:0044085 368 0.034
protein phosphorylation GO:0006468 345 0.034
positive regulation of apoptotic process GO:0043065 154 0.033
developmental process involved in reproduction GO:0003006 159 0.033
positive regulation of neuron projection development GO:0010976 99 0.033
response to cocaine GO:0042220 39 0.033
regulation of synapse structure and activity GO:0050803 21 0.033
cell morphogenesis GO:0000902 142 0.033
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.033
positive regulation of signaling GO:0023056 270 0.033
Rat
response to activity GO:0014823 73 0.033
carboxylic acid metabolic process GO:0019752 289 0.032
regulation of feeding behavior GO:0060259 14 0.032
positive regulation of cell death GO:0010942 184 0.032
cellular response to extracellular stimulus GO:0031668 73 0.032
regulation of rna metabolic process GO:0051252 391 0.031
negative regulation of neuron differentiation GO:0045665 62 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
positive regulation of ion transmembrane transport GO:0034767 24 0.031
forebrain development GO:0030900 98 0.030
brain development GO:0007420 247 0.030
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
axon choice point recognition GO:0016198 2 0.030
regulation of protein metabolic process GO:0051246 289 0.030
dicarboxylic acid transport GO:0006835 34 0.030
response to glucose GO:0009749 136 0.030
membrane depolarization GO:0051899 32 0.029
Mouse
response to nutrient levels GO:0031667 370 0.029
Rat
multicellular organismal reproductive process GO:0048609 233 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.029
Mouse
guanosine containing compound catabolic process GO:1901069 71 0.029
response to inorganic substance GO:0010035 377 0.029
response to vitamin d GO:0033280 34 0.029
cation homeostasis GO:0055080 195 0.029
tissue development GO:0009888 252 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
cell junction organization GO:0034330 21 0.029
cellular response to stress GO:0033554 269 0.029
negative regulation of organ growth GO:0046621 3 0.028
negative regulation of receptor internalization GO:0002091 2 0.028
negative regulation of cardiac muscle tissue development GO:0055026 3 0.028
protein oligomerization GO:0051259 191 0.028
Rat
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.028
adult behavior GO:0030534 16 0.028
Human
nucleoside triphosphate catabolic process GO:0009143 123 0.028
monovalent inorganic cation transport GO:0015672 172 0.028
action potential GO:0001508 54 0.028
response to amphetamine GO:0001975 25 0.028
spinal cord development GO:0021510 27 0.028
regulation of apoptotic process GO:0042981 335 0.028
programmed cell death GO:0012501 392 0.028
rna metabolic process GO:0016070 406 0.027
organic cyclic compound catabolic process GO:1901361 175 0.027
response to amine GO:0014075 46 0.027
negative regulation of cellular component organization GO:0051129 83 0.027
Mouse
neuromuscular synaptic transmission GO:0007274 2 0.027
regulation of transporter activity GO:0032409 50 0.027
Mouse
purine containing compound metabolic process GO:0072521 253 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
sensory perception of pain GO:0019233 73 0.026
positive regulation of nervous system development GO:0051962 178 0.026
organonitrogen compound biosynthetic process GO:1901566 167 0.026
response to growth factor GO:0070848 189 0.025
macromolecular complex assembly GO:0065003 273 0.025
purine nucleoside triphosphate catabolic process GO:0009146 122 0.025
regulation of receptor internalization GO:0002090 6 0.025
receptor mediated endocytosis GO:0006898 42 0.025
small molecule biosynthetic process GO:0044283 124 0.025
negative regulation of nucleotide metabolic process GO:0045980 23 0.025
circadian rhythm GO:0007623 88 0.025
cardiac muscle cell contraction GO:0086003 10 0.024
organic hydroxy compound metabolic process GO:1901615 115 0.024
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.024
male mating behavior GO:0060179 3 0.024
protein localization to synapse GO:0035418 5 0.024
Mouse
multicellular organismal response to stress GO:0033555 25 0.024
nucleobase containing compound catabolic process GO:0034655 152 0.024
cell adhesion GO:0007155 110 0.024
detection of visible light GO:0009584 3 0.024
purine containing compound catabolic process GO:0072523 138 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.023
cellular response to alkaloid GO:0071312 25 0.023
regulation of cell cycle g1 s phase transition GO:1902806 7 0.023
negative regulation of cell development GO:0010721 82 0.023
synaptic vesicle endocytosis GO:0048488 4 0.023
response to ketone GO:1901654 182 0.023
response to electrical stimulus GO:0051602 56 0.023
positive regulation of gene expression GO:0010628 244 0.023
regulation of nucleotide catabolic process GO:0030811 65 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
cell part morphogenesis GO:0032990 123 0.023
Mouse
purine nucleoside catabolic process GO:0006152 124 0.023
actin mediated cell contraction GO:0070252 12 0.022
embryonic axis specification GO:0000578 1 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
negative regulation of lyase activity GO:0051350 8 0.022
regulation of cellular localization GO:0060341 263 0.022
positive regulation of mapk cascade GO:0043410 92 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of developmental growth GO:0048638 45 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
inner ear development GO:0048839 21 0.022
single organism reproductive process GO:0044702 297 0.022
circulatory system development GO:0072359 134 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
regulation of protein modification process GO:0031399 194 0.021
presynaptic membrane organization GO:0097090 4 0.021
defense response GO:0006952 194 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
phospholipid metabolic process GO:0006644 61 0.021
purine ribonucleotide catabolic process GO:0009154 136 0.021
thyroid gland development GO:0030878 1 0.021
cell fate commitment involved in pattern specification GO:0060581 2 0.021
regulation of axonogenesis GO:0050770 37 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
protein localization GO:0008104 191 0.021
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.021
cellular response to drug GO:0035690 30 0.021
response to nicotine GO:0035094 51 0.021
positive regulation of excitatory postsynaptic membrane potential GO:2000463 7 0.020
Mouse
regulation of notch signaling pathway GO:0008593 3 0.020
negative regulation of transport GO:0051051 136 0.020
single organism biosynthetic process GO:0044711 342 0.020
response to insecticide GO:0017085 21 0.020
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.020
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.020
positive regulation of transferase activity GO:0051347 81 0.020
neuron apoptotic process GO:0051402 88 0.020
second messenger mediated signaling GO:0019932 51 0.020
regulation of endocytosis GO:0030100 42 0.020
positive regulation of myoblast proliferation GO:2000288 1 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
response to estrogen GO:0043627 232 0.020
anion transmembrane transport GO:0098656 77 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
glycosyl compound catabolic process GO:1901658 126 0.019
axon extension GO:0048675 26 0.019
regulation of anatomical structure size GO:0090066 135 0.019
cellular amine metabolic process GO:0044106 38 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.019
response to manganese ion GO:0010042 13 0.019
cell projection morphogenesis GO:0048858 123 0.019
Mouse
ovulation GO:0030728 17 0.019
response to temperature stimulus GO:0009266 94 0.019
regulation of organelle organization GO:0033043 80 0.019
Mouse
single organism catabolic process GO:0044712 283 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
negative regulation of adenylate cyclase activity GO:0007194 7 0.019
response to ammonium ion GO:0060359 71 0.018
negative regulation of neuron apoptotic process GO:0043524 45 0.018
positive regulation of blood circulation GO:1903524 65 0.018
gamma aminobutyric acid transport GO:0015812 8 0.018
regulation of receptor activity GO:0010469 29 0.018
Mouse
negative regulation of gamma aminobutyric acid secretion GO:0014053 3 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
protein tetramerization GO:0051262 38 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
n methyl d aspartate receptor clustering GO:0097114 2 0.018
positive regulation of nucleoside metabolic process GO:0045979 55 0.018
gamma aminobutyric acid secretion GO:0014051 6 0.018
amide transport GO:0042886 105 0.018
nucleoside metabolic process GO:0009116 179 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
transcription dna templated GO:0006351 377 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
response to toxic substance GO:0009636 133 0.017
phasic smooth muscle contraction GO:0014821 3 0.017
regulation of growth GO:0040008 105 0.017
regulation of mapk cascade GO:0043408 116 0.017
response to vitamin GO:0033273 131 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
regulation of purine nucleotide catabolic process GO:0033121 65 0.017
glycerolipid metabolic process GO:0046486 67 0.017
regulation of muscle system process GO:0090257 79 0.017
learning or memory GO:0007611 90 0.017
Mouse
regulation of programmed cell death GO:0043067 341 0.017
localization of cell GO:0051674 202 0.017
positive regulation of cytoskeleton organization GO:0051495 26 0.017
regulation of corticotropin secretion GO:0051459 7 0.017
oxidation reduction process GO:0055114 304 0.017
positive regulation of signal transduction GO:0009967 175 0.017
Rat
intracellular transport GO:0046907 185 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
nucleic acid templated transcription GO:0097659 379 0.017
lens fiber cell differentiation GO:0070306 3 0.016
feeding behavior GO:0007631 53 0.016
respiratory gaseous exchange GO:0007585 4 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
jak stat cascade GO:0007259 26 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
skeletal system development GO:0001501 41 0.016
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.016
cell cell junction assembly GO:0007043 7 0.016
cell motility GO:0048870 202 0.016
nucleotide catabolic process GO:0009166 139 0.016
epithelium development GO:0060429 96 0.016
positive regulation of adenylate cyclase activity GO:0045762 12 0.016
single organism cellular localization GO:1902580 102 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
amine metabolic process GO:0009308 38 0.016
response to ph GO:0009268 27 0.016
positive regulation of nucleotide catabolic process GO:0030813 53 0.016
developmental maturation GO:0021700 25 0.016
heterotypic cell cell adhesion GO:0034113 2 0.015
response to reactive oxygen species GO:0000302 120 0.015
cardiac ventricle development GO:0003231 1 0.015
single organism cell adhesion GO:0098602 46 0.015
negative regulation of cell death GO:0060548 229 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
calcium ion transport GO:0006816 131 0.015
regulation of locomotion GO:0040012 148 0.015
aging GO:0007568 241 0.015
cellular response to nutrient levels GO:0031669 60 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
developmental growth GO:0048589 100 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
regulation of vasoconstriction GO:0019229 44 0.015
response to hexose GO:0009746 144 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
somatostatin receptor signaling pathway GO:0038169 4 0.015
isoquinoline alkaloid metabolic process GO:0033076 2 0.015
long term synaptic potentiation GO:0060291 21 0.015
protein catabolic process GO:0030163 30 0.015
regulation of neurotransmitter secretion GO:0046928 19 0.015
regulation of behavioral fear response GO:2000822 3 0.015
biphenyl metabolic process GO:0018879 10 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
multi organism behavior GO:0051705 24 0.014
Human Mouse
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
establishment of protein localization GO:0045184 141 0.014
gastric motility GO:0035482 3 0.014
negative regulation of molecular function GO:0044092 133 0.014
regulation of receptor mediated endocytosis GO:0048259 17 0.014
positive regulation of synaptic transmission cholinergic GO:0032224 6 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
actin filament based movement GO:0030048 16 0.014
lipid modification GO:0030258 52 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
muscle system process GO:0003012 115 0.013
negative regulation of peptide hormone secretion GO:0090278 30 0.013
glucose homeostasis GO:0042593 75 0.013
ras protein signal transduction GO:0007265 29 0.013
cell migration GO:0016477 197 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
positive regulation of renin secretion into blood stream GO:1900135 1 0.013
rna biosynthetic process GO:0032774 380 0.013
heart development GO:0007507 72 0.013
regulation of camp metabolic process GO:0030814 43 0.013
response to testosterone GO:0033574 55 0.013
cellular ketone metabolic process GO:0042180 51 0.013
circadian behavior GO:0048512 24 0.013
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.013
Mouse
regulation of metal ion transport GO:0010959 118 0.013
rhythmic synaptic transmission GO:0060024 1 0.013
cell junction assembly GO:0034329 18 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of actin filament based process GO:0032970 42 0.013
Mouse
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.013
growth GO:0040007 165 0.013
regulation of vascular smooth muscle contraction GO:0003056 3 0.013
long term memory GO:0007616 15 0.013
Mouse
negative regulation of developmental growth GO:0048640 15 0.013
synaptic transmission glycinergic GO:0060012 2 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
alcohol biosynthetic process GO:0046165 38 0.013
response to carbohydrate GO:0009743 183 0.013
memory GO:0007613 54 0.012
Mouse

Shank1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022