Rattus norvegicus

72 known processes

Epas1

endothelial PAS domain protein 1

(Aliases: HLF,Hif2a)

Epas1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of catalytic activity GO:0050790 304 0.492
regulation of cellular protein metabolic process GO:0032268 267 0.485
regulation of molecular function GO:0065009 398 0.372
single organism catabolic process GO:0044712 283 0.357
regulation of cellular catabolic process GO:0031329 101 0.353
Fly
regulation of cell proliferation GO:0042127 359 0.350
Rat
response to hypoxia GO:0001666 231 0.345
nucleoside phosphate catabolic process GO:1901292 140 0.338
positive regulation of locomotion GO:0040017 102 0.338
nucleoside triphosphate metabolic process GO:0009141 144 0.336
organophosphate metabolic process GO:0019637 370 0.334
positive regulation of phosphorus metabolic process GO:0010562 262 0.322
positive regulation of cell communication GO:0010647 271 0.317
regulation of cell migration GO:0030334 128 0.310
Fly
cell migration GO:0016477 197 0.301
Fly
positive regulation of catalytic activity GO:0043085 184 0.299
positive regulation of signaling GO:0023056 270 0.297
regulation of transcription dna templated GO:0006355 374 0.289
positive regulation of intracellular signal transduction GO:1902533 138 0.287
response to decreased oxygen levels GO:0036293 237 0.253
regulation of intracellular signal transduction GO:1902531 218 0.252
tissue development GO:0009888 252 0.249
positive regulation of phosphate metabolic process GO:0045937 262 0.247
response to glucocorticoid GO:0051384 223 0.246
Rat
pro t cell differentiation GO:0002572 1 0.244
cation transport GO:0006812 382 0.243
cellular lipid metabolic process GO:0044255 208 0.229
guanosine containing compound metabolic process GO:1901068 74 0.228
response to oxygen levels GO:0070482 265 0.217
lymphoid progenitor cell differentiation GO:0002320 2 0.216
positive regulation of nucleoside metabolic process GO:0045979 55 0.205
ribonucleoside triphosphate catabolic process GO:0009203 122 0.200
response to oxidative stress GO:0006979 186 0.198
Mouse Rat
positive regulation of biosynthetic process GO:0009891 319 0.196
regulation of signal transduction GO:0009966 318 0.195
cellular response to oxygen containing compound GO:1901701 386 0.194
Rat Fly
negative regulation of programmed cell death GO:0043069 183 0.192
Rat
nucleoside metabolic process GO:0009116 179 0.192
intracellular signal transduction GO:0035556 314 0.192
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.189
purine ribonucleoside catabolic process GO:0046130 124 0.188
organic acid metabolic process GO:0006082 292 0.187
monovalent inorganic cation transport GO:0015672 172 0.186
regulation of phosphate metabolic process GO:0019220 349 0.184
regulation of protein metabolic process GO:0051246 289 0.182
organic substance catabolic process GO:1901575 316 0.182
regulation of kinase activity GO:0043549 117 0.180
positive regulation of multicellular organismal process GO:0051240 387 0.178
positive regulation of cell proliferation GO:0008284 249 0.178
Rat
cell motility GO:0048870 202 0.176
Fly
organic cyclic compound catabolic process GO:1901361 175 0.173
regulation of hydrolase activity GO:0051336 143 0.173
positive regulation of cell migration GO:0030335 96 0.171
regulation of lipid metabolic process GO:0019216 68 0.169
nucleoside phosphate metabolic process GO:0006753 283 0.169
rna metabolic process GO:0016070 406 0.169
response to acid chemical GO:0001101 222 0.164
Rat
ribonucleotide catabolic process GO:0009261 136 0.162
carboxylic acid metabolic process GO:0019752 289 0.159
response to inorganic substance GO:0010035 377 0.156
Rat
catabolic process GO:0009056 351 0.155
Fly
regulation of protein phosphorylation GO:0001932 183 0.155
organophosphate catabolic process GO:0046434 148 0.152
aromatic compound catabolic process GO:0019439 168 0.150
cellular response to endogenous stimulus GO:0071495 377 0.149
Rat Fly
glycosyl compound metabolic process GO:1901657 182 0.149
oxoacid metabolic process GO:0043436 290 0.148
ion transmembrane transport GO:0034220 365 0.147
regulation of catabolic process GO:0009894 113 0.142
Fly
positive regulation of signal transduction GO:0009967 175 0.141
regulation of nucleic acid templated transcription GO:1903506 380 0.138
regulation of phosphorus metabolic process GO:0051174 349 0.137
nucleobase containing small molecule metabolic process GO:0055086 316 0.136
nucleic acid templated transcription GO:0097659 379 0.135
cellular response to organic cyclic compound GO:0071407 202 0.133
Rat
response to estrogen GO:0043627 232 0.132
Rat
regulation of multicellular organismal development GO:2000026 376 0.132
purine ribonucleotide catabolic process GO:0009154 136 0.131
response to peptide GO:1901652 292 0.130
Rat Fly
single organism reproductive process GO:0044702 297 0.129
Mouse Rat Fly
angiogenesis GO:0001525 53 0.128
Mouse
positive regulation of hydrolase activity GO:0051345 86 0.127
regulation of neuron death GO:1901214 115 0.126
Zebrafish
negative regulation of cell death GO:0060548 229 0.125
Rat
central nervous system development GO:0007417 311 0.125
locomotion GO:0040011 237 0.125
Fly
regulation of system process GO:0044057 208 0.124
Mouse Rat
purine ribonucleoside metabolic process GO:0046128 168 0.123
positive regulation of cellular protein metabolic process GO:0032270 167 0.122
guanosine containing compound catabolic process GO:1901069 71 0.121
positive regulation of map kinase activity GO:0043406 46 0.120
wound healing GO:0042060 122 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.119
carbohydrate derivative metabolic process GO:1901135 346 0.119
carbohydrate derivative catabolic process GO:1901136 147 0.119
negative regulation of gene expression GO:0010629 199 0.118
Rat
gtp catabolic process GO:0006184 71 0.116
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.115
ribonucleoside metabolic process GO:0009119 174 0.115
positive regulation of transferase activity GO:0051347 81 0.115
anatomical structure morphogenesis GO:0009653 298 0.114
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 141 0.114
peptide secretion GO:0002790 86 0.112
positive regulation of molecular function GO:0044093 230 0.111
regulation of purine nucleotide catabolic process GO:0033121 65 0.111
lipid metabolic process GO:0006629 283 0.110
gtp metabolic process GO:0046039 72 0.110
purine nucleoside metabolic process GO:0042278 169 0.109
taxis GO:0042330 67 0.109
negative regulation of cell proliferation GO:0008285 119 0.106
nucleobase containing compound catabolic process GO:0034655 152 0.104
purine nucleoside catabolic process GO:0006152 124 0.103
ion homeostasis GO:0050801 212 0.102
Mouse
response to cytokine GO:0034097 215 0.101
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.101
regulation of cellular component movement GO:0051270 150 0.100
Fly
localization of cell GO:0051674 202 0.096
Fly
positive regulation of cell motility GO:2000147 97 0.096
regulation of nucleotide catabolic process GO:0030811 65 0.096
cellular response to hormone stimulus GO:0032870 247 0.095
Rat Fly
inorganic ion transmembrane transport GO:0098660 229 0.095
protein phosphorylation GO:0006468 345 0.094
heart process GO:0003015 57 0.092
Mouse
positive regulation of gene expression GO:0010628 244 0.092
nucleoside triphosphate catabolic process GO:0009143 123 0.091
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.091
sodium ion transmembrane transport GO:0035725 67 0.088
regulation of mesenchymal cell proliferation GO:0010464 4 0.086
regulation of ras gtpase activity GO:0032318 32 0.086
regulation of ion transport GO:0043269 245 0.086
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 1 0.086
regulation of protein modification process GO:0031399 194 0.086
cellular amino acid metabolic process GO:0006520 107 0.085
positive regulation of rna biosynthetic process GO:1902680 197 0.084
purine nucleotide metabolic process GO:0006163 229 0.084
positive regulation of protein phosphorylation GO:0001934 135 0.083
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.082
Rat
cellular cation homeostasis GO:0030003 180 0.082
purine ribonucleotide metabolic process GO:0009150 227 0.082
negative regulation of multicellular organismal process GO:0051241 203 0.081
Rat
regulation of phosphorylation GO:0042325 248 0.081
nucleoside catabolic process GO:0009164 126 0.081
nucleotide metabolic process GO:0009117 279 0.080
neuron development GO:0048666 286 0.080
transmembrane transport GO:0055085 412 0.080
cellular ion homeostasis GO:0006873 184 0.079
response to ethanol GO:0045471 162 0.078
epithelium development GO:0060429 96 0.078
purine containing compound catabolic process GO:0072523 138 0.077
negative regulation of cell communication GO:0010648 158 0.076
secretion by cell GO:0032940 248 0.076
organelle organization GO:0006996 266 0.076
Mouse
glycosyl compound catabolic process GO:1901658 126 0.075
regulation of response to stress GO:0080134 126 0.075
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.074
regulation of protein kinase activity GO:0045859 105 0.074
cellular catabolic process GO:0044248 295 0.073
Fly
ribonucleoside catabolic process GO:0042454 126 0.072
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
positive regulation of gtpase activity GO:0043547 47 0.072
epithelial cell proliferation GO:0050673 54 0.072
response to purine containing compound GO:0014074 126 0.072
Rat
organonitrogen compound catabolic process GO:1901565 179 0.071
sodium ion transport GO:0006814 82 0.071
regulation of nucleotide metabolic process GO:0006140 117 0.070
regulation of rna metabolic process GO:0051252 391 0.070
regulation of small gtpase mediated signal transduction GO:0051056 48 0.070
organ regeneration GO:0031100 101 0.070
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.070
potassium ion transport GO:0006813 97 0.070
response to mechanical stimulus GO:0009612 134 0.069
Rat
response to estradiol GO:0032355 164 0.069
Rat
positive regulation of mapk cascade GO:0043410 92 0.069
positive regulation of transport GO:0051050 245 0.069
signal transduction by phosphorylation GO:0023014 144 0.068
positive regulation of nucleotide catabolic process GO:0030813 53 0.067
regulation of map kinase activity GO:0043405 53 0.066
heart contraction GO:0060047 57 0.066
Mouse
blood circulation GO:0008015 183 0.066
Mouse Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.065
regulation of cell development GO:0060284 263 0.065
positive regulation of protein kinase activity GO:0045860 73 0.065
nucleotide catabolic process GO:0009166 139 0.065
positive regulation of cellular biosynthetic process GO:0031328 295 0.065
positive regulation of cellular catabolic process GO:0031331 71 0.065
Fly
cell substrate adhesion GO:0031589 29 0.064
positive regulation of developmental process GO:0051094 283 0.064
negative regulation of response to stimulus GO:0048585 155 0.064
positive regulation of nervous system development GO:0051962 178 0.064
phototransduction visible light GO:0007603 2 0.063
positive regulation of cell development GO:0010720 176 0.063
neuron differentiation GO:0030182 368 0.063
Zebrafish
positive regulation of phosphorylation GO:0042327 177 0.062
ribose phosphate metabolic process GO:0019693 235 0.062
regulation of cellular amino acid metabolic process GO:0006521 2 0.062
rna biosynthetic process GO:0032774 380 0.062
g protein coupled receptor signaling pathway GO:0007186 242 0.062
nitrogen compound transport GO:0071705 229 0.062
regulation of transferase activity GO:0051338 123 0.061
positive regulation of cell differentiation GO:0045597 217 0.060
negative regulation of signaling GO:0023057 157 0.060
ras protein signal transduction GO:0007265 29 0.060
positive regulation of nucleotide metabolic process GO:0045981 91 0.059
negative regulation of cellular biosynthetic process GO:0031327 161 0.059
Rat
ribonucleotide metabolic process GO:0009259 231 0.058
regulation of programmed cell death GO:0043067 341 0.057
Zebrafish Rat
purine nucleotide catabolic process GO:0006195 136 0.057
head development GO:0060322 247 0.057
positive regulation of ras gtpase activity GO:0032320 28 0.057
response to camp GO:0051591 91 0.055
single organism biosynthetic process GO:0044711 342 0.055
response to toxic substance GO:0009636 133 0.055
Rat
homeostatic process GO:0042592 331 0.055
Mouse Rat
phospholipid metabolic process GO:0006644 61 0.054
cellular response to stress GO:0033554 269 0.054
Human Mouse Rat Fly
transcription dna templated GO:0006351 377 0.054
positive regulation of protein modification process GO:0031401 142 0.054
cellular ketone metabolic process GO:0042180 51 0.053
cellular homeostasis GO:0019725 252 0.053
Rat
cellular response to lipid GO:0071396 201 0.053
Rat
brain development GO:0007420 247 0.053
response to alkaloid GO:0043279 132 0.053
Rat
regulation of cell differentiation GO:0045595 320 0.052
regulation of mapk cascade GO:0043408 116 0.052
positive regulation of nucleic acid templated transcription GO:1903508 197 0.052
regulation of peptide transport GO:0090087 87 0.052
negative regulation of rna metabolic process GO:0051253 123 0.052
Rat
multicellular organism growth GO:0035264 1 0.052
regulation of purine nucleotide metabolic process GO:1900542 115 0.052
cellular response to abiotic stimulus GO:0071214 85 0.052
Rat
peptidyl amino acid modification GO:0018193 126 0.051
regulation of cellular localization GO:0060341 263 0.050
response to nutrient GO:0007584 248 0.050
regulation of lipid kinase activity GO:0043550 7 0.050
anatomical structure formation involved in morphogenesis GO:0048646 83 0.049
Mouse
response to corticosteroid GO:0031960 235 0.049
Rat
metanephric glomerulus morphogenesis GO:0072275 1 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
Rat
glycosaminoglycan biosynthetic process GO:0006024 4 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.048
Rat
positive regulation of response to stimulus GO:0048584 285 0.048
oxidation reduction process GO:0055114 304 0.047
cation homeostasis GO:0055080 195 0.047
Mouse
myeloid progenitor cell differentiation GO:0002318 1 0.047
purine containing compound metabolic process GO:0072521 253 0.047
salivary gland development GO:0007431 3 0.047
metal ion transport GO:0030001 289 0.046
negative regulation of apoptotic process GO:0043066 181 0.046
Rat
regulation of cell motility GO:2000145 131 0.046
Fly
positive regulation of neurogenesis GO:0050769 165 0.046
response to wounding GO:0009611 254 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.045
cellular amine metabolic process GO:0044106 38 0.045
muscle system process GO:0003012 115 0.045
heterocycle catabolic process GO:0046700 167 0.045
cellular response to external stimulus GO:0071496 118 0.044
Rat
gliogenesis GO:0042063 93 0.044
cellular metal ion homeostasis GO:0006875 172 0.044
positive regulation of cellular amine metabolic process GO:0033240 3 0.044
muscle cell proliferation GO:0033002 84 0.043
Rat
cell migration involved in metanephros development GO:0035788 2 0.043
cellular response to cytokine stimulus GO:0071345 127 0.043
Rat
establishment of protein localization GO:0045184 141 0.043
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.043
negative regulation of protein metabolic process GO:0051248 114 0.042
neuron projection development GO:0031175 273 0.042
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.042
Rat
epithelial cell differentiation GO:0030855 71 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.042
response to extracellular stimulus GO:0009991 380 0.042
programmed cell death GO:0012501 392 0.042
Zebrafish Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.042
regulation of locomotion GO:0040012 148 0.041
Fly
aminoglycan biosynthetic process GO:0006023 4 0.041
hormone transport GO:0009914 121 0.041
regulation of gtpase activity GO:0043087 57 0.041
regulation of body fluid levels GO:0050878 90 0.041
dephosphorylation GO:0016311 98 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.041
purine nucleoside triphosphate catabolic process GO:0009146 122 0.041
aging GO:0007568 241 0.040
positive regulation of cellular component movement GO:0051272 102 0.039
regulation of cellular component organization GO:0051128 368 0.039
Fly
actin cytoskeleton organization GO:0030036 73 0.039
divalent metal ion transport GO:0070838 132 0.039
positive regulation of cellular component organization GO:0051130 200 0.038
negative regulation of neuron apoptotic process GO:0043524 45 0.038
cellular response to peptide GO:1901653 133 0.038
Rat Fly
response to bacterium GO:0009617 200 0.037
Rat
blood vessel development GO:0001568 69 0.037
Mouse
organ morphogenesis GO:0009887 75 0.037
small molecule biosynthetic process GO:0044283 124 0.037
small gtpase mediated signal transduction GO:0007264 36 0.037
positive regulation of gtp catabolic process GO:0033126 48 0.037
tube development GO:0035295 89 0.036
Mouse
regulation of neuron projection development GO:0010975 161 0.036
transmission of nerve impulse GO:0019226 42 0.036
regulation of secretion GO:0051046 224 0.035
cellular component biogenesis GO:0044085 368 0.035
sensory perception GO:0007600 101 0.035
Mouse
chemotaxis GO:0006935 66 0.035
smooth muscle cell proliferation GO:0048659 77 0.035
Rat
developmental process involved in reproduction GO:0003006 159 0.035
Mouse Fly
rhythmic process GO:0048511 156 0.035
salivary gland morphogenesis GO:0007435 1 0.035
intracellular protein transport GO:0006886 79 0.035
defense response GO:0006952 194 0.034
reproduction GO:0000003 245 0.034
Rat Fly
positive regulation of rna metabolic process GO:0051254 203 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
Rat
blood vessel morphogenesis GO:0048514 58 0.033
Mouse
cell migration involved in kidney development GO:0035787 2 0.033
b cell differentiation GO:0030183 2 0.033
regulation of gtp catabolic process GO:0033124 58 0.033
cellular response to peptide hormone stimulus GO:0071375 120 0.033
Rat Fly
response to external biotic stimulus GO:0043207 221 0.033
Rat
inorganic cation transmembrane transport GO:0098662 202 0.033
regulation of smooth muscle cell proliferation GO:0048660 75 0.033
Rat
cell matrix adhesion GO:0007160 19 0.033
positive regulation of protein metabolic process GO:0051247 178 0.033
response to monosaccharide GO:0034284 159 0.033
Rat
response to nutrient levels GO:0031667 370 0.033
cell chemotaxis GO:0060326 31 0.032
response to lipopolysaccharide GO:0032496 191 0.032
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.032
amide transport GO:0042886 105 0.032
vesicle mediated transport GO:0016192 181 0.032
regulation of apoptotic process GO:0042981 335 0.031
Zebrafish Rat
sensory organ development GO:0007423 74 0.031
cell cell signaling GO:0007267 335 0.031
lipid modification GO:0030258 52 0.031
chemical homeostasis GO:0048878 292 0.031
Mouse Rat
mapk cascade GO:0000165 140 0.031
peptide transport GO:0015833 97 0.031
response to hexose GO:0009746 144 0.031
Rat
ureteric bud development GO:0001657 14 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.030
neuron death GO:0070997 127 0.030
Zebrafish
multicellular organism reproduction GO:0032504 233 0.030
Rat Fly
retina morphogenesis in camera type eye GO:0060042 1 0.030
multi organism reproductive process GO:0044703 262 0.030
Rat Fly
ossification GO:0001503 70 0.030
purinergic receptor signaling pathway GO:0035587 10 0.030
s shaped body morphogenesis GO:0072050 2 0.030
regulation of blood circulation GO:1903522 110 0.030
Mouse Rat
positive regulation of lipid kinase activity GO:0090218 2 0.029
cellular divalent inorganic cation homeostasis GO:0072503 162 0.029
regulation of muscle system process GO:0090257 79 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
Rat Fly
regulation of sodium ion transport GO:0002028 21 0.029
hormone secretion GO:0046879 115 0.028
cellular chemical homeostasis GO:0055082 247 0.028
Rat
single organism cell adhesion GO:0098602 46 0.028
positive regulation of epithelial cell migration GO:0010634 13 0.028
regulation of translation GO:0006417 27 0.028
insulin secretion GO:0030073 69 0.028
response to hydrogen peroxide GO:0042542 89 0.028
Rat
calcium ion homeostasis GO:0055074 162 0.028
negative regulation of cellular protein metabolic process GO:0032269 106 0.028
cellular component morphogenesis GO:0032989 155 0.028
activation of phospholipase d activity GO:0031584 2 0.027
secretion GO:0046903 307 0.027
metanephric comma shaped body morphogenesis GO:0072278 2 0.027
regeneration GO:0031099 163 0.027
glial cell differentiation GO:0010001 65 0.027
cation transmembrane transport GO:0098655 263 0.027
regulation of heart contraction GO:0008016 48 0.027
Mouse
regulation of hormone secretion GO:0046883 106 0.027
female sex differentiation GO:0046660 59 0.027
positive regulation of kinase activity GO:0033674 77 0.027
positive regulation of lipid metabolic process GO:0045834 33 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
regulation of protein serine threonine kinase activity GO:0071900 64 0.026
cellular response to insulin stimulus GO:0032869 81 0.026
Rat Fly
amine metabolic process GO:0009308 38 0.026
regulation of neurogenesis GO:0050767 247 0.026
regulation of neuron differentiation GO:0045664 208 0.026
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
response to insulin GO:0032868 133 0.026
Rat Fly
metal ion homeostasis GO:0055065 186 0.025
Mouse
negative regulation of b cell differentiation GO:0045578 1 0.025
positive regulation of focal adhesion assembly GO:0051894 2 0.025
regulation of nucleoside metabolic process GO:0009118 66 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
cellular component movement GO:0006928 248 0.025
Fly
regulation of metal ion transport GO:0010959 118 0.025
proteolysis GO:0006508 175 0.025
regulation of cell projection organization GO:0031344 175 0.024
anion transmembrane transport GO:0098656 77 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
regulation of hormone levels GO:0010817 187 0.024
regulation of peptide secretion GO:0002791 82 0.024
negative regulation of phosphorus metabolic process GO:0010563 80 0.024
negative regulation of signal transduction GO:0009968 83 0.024
olfactory bulb interneuron differentiation GO:0021889 1 0.024
negative regulation of metabolic process GO:0009892 331 0.024
Rat
generation of precursor metabolites and energy GO:0006091 62 0.024
negative regulation of rna biosynthetic process GO:1902679 118 0.023
Rat
actin filament based process GO:0030029 86 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.023
cell projection organization GO:0030030 302 0.023
eye development GO:0001654 50 0.023
regulation of response to wounding GO:1903034 69 0.023
vasodilation GO:0042311 44 0.023
hexose metabolic process GO:0019318 58 0.023
steroid metabolic process GO:0008202 73 0.022
peptidyl tyrosine phosphorylation GO:0018108 72 0.022
cellular component assembly GO:0022607 360 0.022
neurological system process GO:0050877 219 0.022
Mouse
cellular calcium ion homeostasis GO:0006874 160 0.022
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.022
synaptic transmission GO:0007268 235 0.022
positive regulation of response to external stimulus GO:0032103 51 0.022
negative regulation of developmental process GO:0051093 125 0.022
positive regulation of blood circulation GO:1903524 65 0.022
fatty acid metabolic process GO:0006631 99 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of synaptic transmission GO:0050804 141 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
positive regulation of catabolic process GO:0009896 78 0.022
Fly
smooth muscle cell migration GO:0014909 36 0.022
positive regulation of chemotaxis GO:0050921 23 0.022
response to vitamin GO:0033273 131 0.021
regulation of nervous system development GO:0051960 264 0.021
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.021
response to glucose GO:0009749 136 0.021
Rat
apoptotic process GO:0006915 381 0.021
Zebrafish Rat
response to light stimulus GO:0009416 52 0.021
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.021
anion transport GO:0006820 178 0.021
response to corticosterone GO:0051412 40 0.021
negative regulation of phosphate metabolic process GO:0045936 80 0.020
circulatory system process GO:0003013 183 0.020
Mouse Rat
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.020
regulation of b cell differentiation GO:0045577 1 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.020
gamete generation GO:0007276 124 0.020
Fly
regulation of erk1 and erk2 cascade GO:0070372 41 0.020
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 3 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
pyruvate metabolic process GO:0006090 27 0.020
positive regulation of ion transport GO:0043270 94 0.020
regulation of behavior GO:0050795 61 0.020
regulation of transcription regulatory region dna binding GO:2000677 4 0.020
development of primary female sexual characteristics GO:0046545 56 0.020
negative regulation of transport GO:0051051 136 0.020
kidney mesenchyme development GO:0072074 2 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
Rat
positive regulation of transcription dna templated GO:0045893 197 0.019
kidney development GO:0001822 67 0.019
regulation of homeostatic process GO:0032844 101 0.019
biological adhesion GO:0022610 110 0.019
reproductive process GO:0022414 372 0.019
Mouse Rat Fly
positive regulation of phospholipase activity GO:0010518 10 0.019
positive regulation of peptide secretion GO:0002793 52 0.019
vascular endothelial growth factor signaling pathway GO:0038084 4 0.019
gonad development GO:0008406 104 0.019
cardiovascular system development GO:0072358 134 0.019
Mouse
multi multicellular organism process GO:0044706 138 0.019
Rat
regulation of insulin secretion GO:0050796 65 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
spermatogenesis GO:0007283 99 0.019
regulation of tube size GO:0035150 89 0.019
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.019
vascular process in circulatory system GO:0003018 96 0.018
Rat
circulatory system development GO:0072359 134 0.018
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.018
Rat Fly
sulfur compound metabolic process GO:0006790 70 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.018
pancreatic stellate cell proliferation GO:0072343 2 0.018
positive regulation of endothelial cell migration GO:0010595 4 0.018
neuron apoptotic process GO:0051402 88 0.018
Zebrafish
sexual reproduction GO:0019953 148 0.018
Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.018
metanephric mesenchyme development GO:0072075 2 0.018
cell activation GO:0001775 97 0.018
regulation of chemotaxis GO:0050920 29 0.018
neuron projection morphogenesis GO:0048812 122 0.018
regulation of response to external stimulus GO:0032101 106 0.018
regulation of cellular response to growth factor stimulus GO:0090287 15 0.017
carbohydrate catabolic process GO:0016052 40 0.017
cell cell junction organization GO:0045216 20 0.017
smad protein complex assembly GO:0007183 1 0.017
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.017
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.017
regulation of phospholipase c activity GO:1900274 9 0.017
female mating behavior GO:0060180 6 0.017
macromolecule localization GO:0033036 252 0.017
retina development in camera type eye GO:0060041 27 0.017
regulation of triglyceride biosynthetic process GO:0010866 4 0.017
activation of protein kinase activity GO:0032147 47 0.016

Epas1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.054
inherited metabolic disorder DOID:655 0 0.040
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018