Rattus norvegicus

0 known processes

Agmat

agmatine ureohydrolase (agmatinase)

Agmat biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell death GO:0060548 229 0.102
apoptotic process GO:0006915 381 0.077
response to carbohydrate GO:0009743 183 0.067
regulation of multicellular organismal development GO:2000026 376 0.065
response to monosaccharide GO:0034284 159 0.065
gland development GO:0048732 155 0.059
response to ketone GO:1901654 182 0.059
negative regulation of apoptotic process GO:0043066 181 0.056
cellular response to stress GO:0033554 269 0.055
regulation of programmed cell death GO:0043067 341 0.055
programmed cell death GO:0012501 392 0.055
cellular catabolic process GO:0044248 295 0.053
regulation of apoptotic process GO:0042981 335 0.053
cellular component assembly GO:0022607 360 0.053
catabolic process GO:0009056 351 0.052
organic substance catabolic process GO:1901575 316 0.052
homeostatic process GO:0042592 331 0.052
organic acid transport GO:0015849 116 0.052
response to glucocorticoid GO:0051384 223 0.051
central nervous system development GO:0007417 311 0.050
positive regulation of cell proliferation GO:0008284 249 0.050
response to estradiol GO:0032355 164 0.050
regulation of cell proliferation GO:0042127 359 0.048
negative regulation of programmed cell death GO:0043069 183 0.045
response to extracellular stimulus GO:0009991 380 0.045
regeneration GO:0031099 163 0.044
transmembrane transport GO:0055085 412 0.044
response to inorganic substance GO:0010035 377 0.043
response to nutrient levels GO:0031667 370 0.042
carboxylic acid transport GO:0046942 115 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
response to corticosteroid GO:0031960 235 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
response to wounding GO:0009611 254 0.037
response to peptide GO:1901652 292 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
regulation of rna metabolic process GO:0051252 391 0.034
chemical homeostasis GO:0048878 292 0.034
positive regulation of developmental process GO:0051094 283 0.034
regulation of anatomical structure morphogenesis GO:0022603 141 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
response to glucose GO:0009749 136 0.033
positive regulation of gene expression GO:0010628 244 0.033
positive regulation of cell death GO:0010942 184 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
transcription dna templated GO:0006351 377 0.032
brain development GO:0007420 247 0.032
regulation of catalytic activity GO:0050790 304 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
protein complex assembly GO:0006461 263 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
rna metabolic process GO:0016070 406 0.031
response to peptide hormone GO:0043434 278 0.031
regulation of molecular function GO:0065009 398 0.031
organophosphate metabolic process GO:0019637 370 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
single organism biosynthetic process GO:0044711 342 0.030
nitrogen compound transport GO:0071705 229 0.030
response to external biotic stimulus GO:0043207 221 0.030
protein complex subunit organization GO:0071822 302 0.030
response to other organism GO:0051707 220 0.030
cellular response to endogenous stimulus GO:0071495 377 0.029
positive regulation of biosynthetic process GO:0009891 319 0.028
anion transport GO:0006820 178 0.028
cellular component biogenesis GO:0044085 368 0.028
oxoacid metabolic process GO:0043436 290 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
cellular homeostasis GO:0019725 252 0.028
proteolysis GO:0006508 175 0.028
regulation of neurogenesis GO:0050767 247 0.028
protein oligomerization GO:0051259 191 0.028
cation transport GO:0006812 382 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
response to metal ion GO:0010038 253 0.028
response to molecule of fungal origin GO:0002238 3 0.027
regulation of cellular component movement GO:0051270 150 0.027
localization of cell GO:0051674 202 0.027
response to toxic substance GO:0009636 133 0.027
rna biosynthetic process GO:0032774 380 0.027
negative regulation of metabolic process GO:0009892 331 0.027
hepatocyte proliferation GO:0072574 3 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of rna metabolic process GO:0051254 203 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
response to oxygen levels GO:0070482 265 0.026
cellular component movement GO:0006928 248 0.026
regulation of cellular component organization GO:0051128 368 0.026
organic anion transport GO:0015711 132 0.026
macromolecular complex assembly GO:0065003 273 0.025
secretion GO:0046903 307 0.025
secretion by cell GO:0032940 248 0.025
organelle organization GO:0006996 266 0.025
response to hexose GO:0009746 144 0.025
response to estrogen GO:0043627 232 0.025
single organism reproductive process GO:0044702 297 0.025
positive regulation of apoptotic process GO:0043065 154 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of cell projection organization GO:0031344 175 0.024
response to lipopolysaccharide GO:0032496 191 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
nucleotide metabolic process GO:0009117 279 0.024
purine containing compound metabolic process GO:0072521 253 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
regulation of protein metabolic process GO:0051246 289 0.023
organic hydroxy compound transport GO:0015850 77 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
hepaticobiliary system development GO:0061008 90 0.022
positive regulation of transport GO:0051050 245 0.022
fibrinolysis GO:0042730 2 0.022
positive regulation of nervous system development GO:0051962 178 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
response to acid chemical GO:0001101 222 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
regulation of response to stress GO:0080134 126 0.022
positive regulation of cell motility GO:2000147 97 0.022
gliogenesis GO:0042063 93 0.022
protein complex biogenesis GO:0070271 263 0.022
cellular amine metabolic process GO:0044106 38 0.022
negative regulation of gene expression GO:0010629 199 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
cellular chemical homeostasis GO:0055082 247 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
organic acid metabolic process GO:0006082 292 0.021
regulation of transcription dna templated GO:0006355 374 0.021
negative regulation of developmental process GO:0051093 125 0.021
cell projection organization GO:0030030 302 0.021
cell migration GO:0016477 197 0.021
regulation of cell development GO:0060284 263 0.021
liver development GO:0001889 90 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
ion transmembrane transport GO:0034220 365 0.021
intracellular signal transduction GO:0035556 314 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
response to radiation GO:0009314 137 0.020
positive regulation of blood coagulation GO:0030194 4 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
single organism catabolic process GO:0044712 283 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
head development GO:0060322 247 0.020
nucleic acid templated transcription GO:0097659 379 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
regulation of synaptic transmission GO:0050804 141 0.020
protein phosphorylation GO:0006468 345 0.020
positive regulation of cell development GO:0010720 176 0.020
positive regulation of secretion GO:0051047 140 0.020
locomotion GO:0040011 237 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.019
wound healing GO:0042060 122 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
mesoderm development GO:0007498 2 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
multi organism reproductive process GO:0044703 262 0.019
inflammatory response GO:0006954 150 0.019
hemostasis GO:0007599 26 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
epithelial cell proliferation GO:0050673 54 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
response to ethanol GO:0045471 162 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
regulation of locomotion GO:0040012 148 0.018
regulation of body fluid levels GO:0050878 90 0.018
tissue development GO:0009888 252 0.018
response to hypoxia GO:0001666 231 0.018
regulation of cell migration GO:0030334 128 0.018
telencephalon development GO:0021537 62 0.018
reproduction GO:0000003 245 0.018
neuron projection development GO:0031175 273 0.018
aging GO:0007568 241 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
tissue remodeling GO:0048771 40 0.018
positive regulation of programmed cell death GO:0043068 157 0.017
cell motility GO:0048870 202 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
response to amino acid GO:0043200 75 0.017
amino acid transport GO:0006865 70 0.017
regulation of nervous system development GO:0051960 264 0.017
regulation of neuron differentiation GO:0045664 208 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
positive regulation of cell migration GO:0030335 96 0.017
regulation of plasminogen activation GO:0010755 2 0.017
response to oxidative stress GO:0006979 186 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
regulation of system process GO:0044057 208 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
cellular response to hexose stimulus GO:0071331 65 0.016
response to camp GO:0051591 91 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
carboxylic acid biosynthetic process GO:0046394 83 0.016
plasminogen activation GO:0031639 2 0.016
regulation of response to wounding GO:1903034 69 0.016
cellular response to external stimulus GO:0071496 118 0.016
response to nutrient GO:0007584 248 0.016
response to biotic stimulus GO:0009607 226 0.016
multicellular organism reproduction GO:0032504 233 0.016
positive regulation of molecular function GO:0044093 230 0.016
cellular amino acid biosynthetic process GO:0008652 32 0.016
amine metabolic process GO:0009308 38 0.015
developmental growth GO:0048589 100 0.015
response to bacterium GO:0009617 200 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
developmental process involved in reproduction GO:0003006 159 0.015
protein processing GO:0016485 68 0.015
neuron development GO:0048666 286 0.015
organ regeneration GO:0031100 101 0.015
single organism intracellular transport GO:1902582 166 0.015
neuron differentiation GO:0030182 368 0.015
regulation of cell differentiation GO:0045595 320 0.015
aromatic compound catabolic process GO:0019439 168 0.015
choline transport GO:0015871 4 0.015
cellular response to lipid GO:0071396 201 0.015
regulation of neuron projection development GO:0010975 161 0.015
monocarboxylic acid transport GO:0015718 52 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
response to growth factor GO:0070848 189 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
response to vitamin GO:0033273 131 0.014
positive regulation of signaling GO:0023056 270 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
metal ion transport GO:0030001 289 0.014
reproductive process GO:0022414 372 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
macromolecule catabolic process GO:0009057 58 0.014
heterocycle catabolic process GO:0046700 167 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
regulation of protein processing GO:0070613 50 0.014
glucose homeostasis GO:0042593 75 0.014
regulation of fibrinolysis GO:0051917 2 0.014
organic acid biosynthetic process GO:0016053 83 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
regulation of cellular localization GO:0060341 263 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cellular ketone metabolic process GO:0042180 51 0.014
negative regulation of fibrinolysis GO:0051918 2 0.014
coagulation GO:0050817 28 0.014
cellular ion homeostasis GO:0006873 184 0.013
defense response GO:0006952 194 0.013
neuron death GO:0070997 127 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
cellular response to fluid shear stress GO:0071498 4 0.013
neurological system process GO:0050877 219 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
response to decreased oxygen levels GO:0036293 237 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
cell type specific apoptotic process GO:0097285 134 0.013
cellular response to carbohydrate stimulus GO:0071322 72 0.013
regulation of cell motility GO:2000145 131 0.013
forebrain development GO:0030900 98 0.013
regulation of secretion by cell GO:1903530 208 0.013
regulation of phosphorylation GO:0042325 248 0.013
regulation of secretion GO:0051046 224 0.013
response to mechanical stimulus GO:0009612 134 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
multicellular organism growth GO:0035264 1 0.013
negative regulation of molecular function GO:0044092 133 0.013
protein localization GO:0008104 191 0.013
circulatory system development GO:0072359 134 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of hemostasis GO:1900048 4 0.012
cation transmembrane transport GO:0098655 263 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
spermatogenesis GO:0007283 99 0.012
regulation of anatomical structure size GO:0090066 135 0.012
mapk cascade GO:0000165 140 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
carbohydrate homeostasis GO:0033500 75 0.012
female pregnancy GO:0007565 122 0.012
regulation of response to external stimulus GO:0032101 106 0.012
cell activation GO:0001775 97 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
regulation of protein kinase activity GO:0045859 105 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of ion transport GO:0043269 245 0.012
sterol homeostasis GO:0055092 3 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
liver morphogenesis GO:0072576 3 0.012
response to temperature stimulus GO:0009266 94 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
regulation of map kinase activity GO:0043405 53 0.012
ras protein signal transduction GO:0007265 29 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
chemosensory behavior GO:0007635 2 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
regulation of neuron death GO:1901214 115 0.012
response to ammonium ion GO:0060359 71 0.012
negative regulation of innate immune response GO:0045824 4 0.012
nucleoside metabolic process GO:0009116 179 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
single organism organelle organization GO:1902589 180 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
negative regulation of signaling GO:0023057 157 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
sodium ion transport GO:0006814 82 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
cellular response to alcohol GO:0097306 87 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
sexual reproduction GO:0019953 148 0.011
reproductive system development GO:0061458 128 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
olfactory behavior GO:0042048 2 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
neuromuscular process GO:0050905 2 0.011
glial cell differentiation GO:0010001 65 0.011
reproductive structure development GO:0048608 128 0.011
response to purine containing compound GO:0014074 126 0.011
macromolecule localization GO:0033036 252 0.011
protein transport GO:0015031 132 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
cholesterol homeostasis GO:0042632 3 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
positive regulation of ion transport GO:0043270 94 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
cellular response to oxygen levels GO:0071453 60 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
response to activity GO:0014823 73 0.010
single organism cellular localization GO:1902580 102 0.010
amide transport GO:0042886 105 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
divalent metal ion transport GO:0070838 132 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
small molecule biosynthetic process GO:0044283 124 0.010
dendrite development GO:0016358 72 0.010
regulation of immune system process GO:0002682 123 0.010
cell projection morphogenesis GO:0048858 123 0.010
synaptic transmission GO:0007268 235 0.010
endocytosis GO:0006897 84 0.010
gamete generation GO:0007276 124 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
lipid metabolic process GO:0006629 283 0.010
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.010
anion transmembrane transport GO:0098656 77 0.010

Agmat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.016
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.011