Rattus norvegicus

58 known processes

Ryr2

ryanodine receptor 2, cardiac

(Aliases: RyR)

Ryr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.463
Mouse
transmembrane transport GO:0055085 412 0.285
divalent inorganic cation homeostasis GO:0072507 165 0.265
enzyme linked receptor protein signaling pathway GO:0007167 116 0.253
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.238
Human
chemical homeostasis GO:0048878 292 0.210
neuron differentiation GO:0030182 368 0.199
positive regulation of response to stimulus GO:0048584 285 0.197
neuron neuron synaptic transmission GO:0007270 60 0.181
purine nucleotide metabolic process GO:0006163 229 0.180
Human
intracellular signal transduction GO:0035556 314 0.164
Human Mouse
regulation of system process GO:0044057 208 0.162
Human Mouse
positive regulation of cell communication GO:0010647 271 0.160
heart contraction GO:0060047 57 0.151
Human Mouse
synaptic transmission glutamatergic GO:0035249 33 0.151
cellular response to hormone stimulus GO:0032870 247 0.150
regulation of membrane potential GO:0042391 110 0.149
Mouse
synapse organization GO:0050808 46 0.142
nucleotide metabolic process GO:0009117 279 0.142
Human
response to hypoxia GO:0001666 231 0.141
Mouse
metal ion homeostasis GO:0055065 186 0.137
cellular chemical homeostasis GO:0055082 247 0.134
regulation of homeostatic process GO:0032844 101 0.134
Human Mouse Rat
cellular ion homeostasis GO:0006873 184 0.133
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.133
homeostatic process GO:0042592 331 0.131
cation transport GO:0006812 382 0.130
metal ion transport GO:0030001 289 0.129
dicarboxylic acid transport GO:0006835 34 0.128
cellular metal ion homeostasis GO:0006875 172 0.124
ion transmembrane transport GO:0034220 365 0.122
positive regulation of phosphate metabolic process GO:0045937 262 0.120
Human
regulation of purine nucleotide metabolic process GO:1900542 115 0.117
Human
cation homeostasis GO:0055080 195 0.117
positive regulation of multicellular organismal process GO:0051240 387 0.116
Mouse
l glutamate import GO:0051938 2 0.116
protein phosphorylation GO:0006468 345 0.112
regulation of phosphorylation GO:0042325 248 0.110
cellular component biogenesis GO:0044085 368 0.104
carboxylic acid transport GO:0046942 115 0.103
regulation of heart contraction GO:0008016 48 0.098
Human Mouse
organophosphate metabolic process GO:0019637 370 0.097
Human
cellular homeostasis GO:0019725 252 0.095
response to estrogen GO:0043627 232 0.092
secretion GO:0046903 307 0.092
signal transduction by phosphorylation GO:0023014 144 0.091
ion homeostasis GO:0050801 212 0.090
cellular nitrogen compound catabolic process GO:0044270 163 0.089
Human
carbohydrate derivative metabolic process GO:1901135 346 0.089
Human
response to nutrient levels GO:0031667 370 0.089
reproductive process GO:0022414 372 0.087
regulation of neurotransmitter levels GO:0001505 42 0.085
regulation of molecular function GO:0065009 398 0.084
Human Mouse
protein complex subunit organization GO:0071822 302 0.084
negative regulation of signaling GO:0023057 157 0.083
regulation of cellular localization GO:0060341 263 0.083
Mouse
response to insulin GO:0032868 133 0.082
potassium ion transport GO:0006813 97 0.082
transcription dna templated GO:0006351 377 0.080
Mouse
cell projection morphogenesis GO:0048858 123 0.079
regulation of cellular catabolic process GO:0031329 101 0.079
Human
regulation of programmed cell death GO:0043067 341 0.079
positive regulation of nervous system development GO:0051962 178 0.078
nucleobase containing small molecule metabolic process GO:0055086 316 0.077
Human
inorganic cation transmembrane transport GO:0098662 202 0.077
response to blue light GO:0009637 1 0.076
glutamate receptor signaling pathway GO:0007215 43 0.076
amine metabolic process GO:0009308 38 0.076
development of primary sexual characteristics GO:0045137 107 0.075
anatomical structure morphogenesis GO:0009653 298 0.075
Mouse
cell projection organization GO:0030030 302 0.074
ribonucleotide metabolic process GO:0009259 231 0.074
Human
aromatic compound catabolic process GO:0019439 168 0.073
Human
neuron projection development GO:0031175 273 0.073
regulation of nervous system development GO:0051960 264 0.072
positive regulation of nucleotide metabolic process GO:0045981 91 0.072
Human
regulation of catabolic process GO:0009894 113 0.072
Human
divalent inorganic cation transport GO:0072511 134 0.070
nucleoside phosphate metabolic process GO:0006753 283 0.069
Human
dendrite morphogenesis GO:0048813 43 0.069
macromolecular complex subunit organization GO:0043933 339 0.069
regulation of phosphorus metabolic process GO:0051174 349 0.067
Human
protein oligomerization GO:0051259 191 0.067
response to mechanical stimulus GO:0009612 134 0.065
nucleobase containing compound catabolic process GO:0034655 152 0.063
Human
single organism catabolic process GO:0044712 283 0.062
Human
ras protein signal transduction GO:0007265 29 0.062
regulation of nucleotide metabolic process GO:0006140 117 0.061
Human
gonad development GO:0008406 104 0.061
developmental process involved in reproduction GO:0003006 159 0.059
positive regulation of signaling GO:0023056 270 0.059
monovalent inorganic cation transport GO:0015672 172 0.058
cellular cation homeostasis GO:0030003 180 0.058
regulation of actin filament based process GO:0032970 42 0.058
Mouse
regulation of rna metabolic process GO:0051252 391 0.058
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 48 0.058
cardiac muscle cell contraction GO:0086003 10 0.057
muscle contraction GO:0006936 88 0.057
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 122 0.057
Human
neurotransmitter transport GO:0006836 42 0.056
cellular response to organic cyclic compound GO:0071407 202 0.056
Human Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.056
Human
amino acid transport GO:0006865 70 0.055
regulation of purine nucleotide catabolic process GO:0033121 65 0.055
Human
regulation of neurogenesis GO:0050767 247 0.054
cellular response to nitrogen compound GO:1901699 210 0.054
Human Mouse
cellular response to organonitrogen compound GO:0071417 197 0.054
Human Mouse
sensory perception of pain GO:0019233 73 0.054
purine containing compound metabolic process GO:0072521 253 0.053
Human
cellular component movement GO:0006928 248 0.053
cellular divalent inorganic cation homeostasis GO:0072503 162 0.053
ribose phosphate metabolic process GO:0019693 235 0.053
Human
cellular component morphogenesis GO:0032989 155 0.052
negative regulation of cell death GO:0060548 229 0.052
inorganic ion transmembrane transport GO:0098660 229 0.050
cellular amine metabolic process GO:0044106 38 0.050
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.050
regulation of secretion GO:0051046 224 0.049
monosaccharide metabolic process GO:0005996 61 0.049
carboxylic acid metabolic process GO:0019752 289 0.049
central nervous system development GO:0007417 311 0.049
negative regulation of apoptotic process GO:0043066 181 0.048
regulation of signal transduction GO:0009966 318 0.047
cytosolic calcium ion homeostasis GO:0051480 140 0.047
single organism reproductive process GO:0044702 297 0.047
purine containing compound catabolic process GO:0072523 138 0.047
Human
regulation of cellular amine metabolic process GO:0033238 8 0.046
positive regulation of phosphorus metabolic process GO:0010562 262 0.046
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.046
Human
cellular calcium ion homeostasis GO:0006874 160 0.046
negative regulation of cell communication GO:0010648 158 0.045
regulation of hormone levels GO:0010817 187 0.045
cell morphogenesis GO:0000902 142 0.045
secretion by cell GO:0032940 248 0.045
regulation of nucleoside metabolic process GO:0009118 66 0.044
Human
response to decreased oxygen levels GO:0036293 237 0.044
Mouse
regulation of apoptotic process GO:0042981 335 0.043
protein complex biogenesis GO:0070271 263 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
synaptic transmission GO:0007268 235 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.043
regulation of cell proliferation GO:0042127 359 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
Human
blood circulation GO:0008015 183 0.041
Human Mouse
mapk cascade GO:0000165 140 0.041
multicellular organismal reproductive process GO:0048609 233 0.041
organic substance catabolic process GO:1901575 316 0.040
Human
biological adhesion GO:0022610 110 0.040
regulation of transmembrane transport GO:0034762 122 0.040
Human Mouse
purine nucleotide catabolic process GO:0006195 136 0.040
Human
ribose phosphate biosynthetic process GO:0046390 87 0.040
oxoacid metabolic process GO:0043436 290 0.040
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.040
g protein coupled receptor signaling pathway GO:0007186 242 0.039
Mouse
action potential GO:0001508 54 0.039
Mouse
muscle system process GO:0003012 115 0.039
Human Mouse
macromolecular complex assembly GO:0065003 273 0.039
regulation of growth GO:0040008 105 0.039
ribonucleoside triphosphate catabolic process GO:0009203 122 0.039
Human
gtp metabolic process GO:0046039 72 0.039
regulation of hydrolase activity GO:0051336 143 0.038
Human
cellular response to endogenous stimulus GO:0071495 377 0.038
Human Mouse
glycosyl compound metabolic process GO:1901657 182 0.037
Human
response to peptide GO:1901652 292 0.037
sensory perception GO:0007600 101 0.037
regulation of ion transmembrane transport GO:0034765 121 0.037
Human Mouse
apoptotic process GO:0006915 381 0.037
Human Mouse
regulation of metal ion transport GO:0010959 118 0.037
Human Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.037
Human
cellular response to insulin stimulus GO:0032869 81 0.036
organic acid transport GO:0015849 116 0.036
cellular component assembly GO:0022607 360 0.036
cellular macromolecule localization GO:0070727 122 0.036
Human
sex differentiation GO:0007548 113 0.036
monocarboxylic acid metabolic process GO:0032787 152 0.035
saliva secretion GO:0046541 3 0.035
rhythmic process GO:0048511 156 0.035
positive regulation of somatostatin secretion GO:0090274 4 0.035
regulation of transcription dna templated GO:0006355 374 0.035
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.035
Human
reproductive system development GO:0061458 128 0.035
negative regulation of phosphorus metabolic process GO:0010563 80 0.034
head development GO:0060322 247 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
cation transmembrane transport GO:0098655 263 0.034
rhythmic synaptic transmission GO:0060024 1 0.033
regulation of neuron differentiation GO:0045664 208 0.033
ribonucleoside metabolic process GO:0009119 174 0.033
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
Human
cellular response to peptide hormone stimulus GO:0071375 120 0.033
regulation of hormone secretion GO:0046883 106 0.033
positive regulation of cell development GO:0010720 176 0.033
organic acid metabolic process GO:0006082 292 0.033
peptidyl tyrosine phosphorylation GO:0018108 72 0.032
positive regulation of signal transduction GO:0009967 175 0.032
signal release GO:0023061 145 0.032
regulation of body fluid levels GO:0050878 90 0.032
dendritic spine morphogenesis GO:0060997 9 0.032
regulation of synapse assembly GO:0051963 15 0.032
regulation of synaptic transmission GO:0050804 141 0.032
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.032
regulation of anatomical structure size GO:0090066 135 0.031
carbohydrate derivative catabolic process GO:1901136 147 0.031
Human
developmental induction GO:0031128 2 0.031
ribonucleotide catabolic process GO:0009261 136 0.031
Human
wound healing GO:0042060 122 0.031
heart process GO:0003015 57 0.031
Human Mouse
multi organism reproductive process GO:0044703 262 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
anion transport GO:0006820 178 0.031
cell part morphogenesis GO:0032990 123 0.030
glycosyl compound catabolic process GO:1901658 126 0.030
Human
catabolic process GO:0009056 351 0.030
Human
regulation of synapse organization GO:0050807 19 0.030
rna metabolic process GO:0016070 406 0.030
Mouse
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.030
regulation of developmental growth GO:0048638 45 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of gtpase activity GO:0043087 57 0.029
regulation of cell development GO:0060284 263 0.029
neurological system process GO:0050877 219 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.028
Mouse
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.028
regulation of synaptic transmission glutamatergic GO:0051966 26 0.028
mechanoreceptor differentiation GO:0042490 2 0.028
exploration behavior GO:0035640 1 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
Human
cellular response to oxygen containing compound GO:1901701 386 0.027
response to extracellular stimulus GO:0009991 380 0.027
regulation of muscle contraction GO:0006937 53 0.027
Human Mouse
cellular ketone metabolic process GO:0042180 51 0.027
positive regulation of synaptic transmission glutamatergic GO:0051968 13 0.027
positive regulation of catabolic process GO:0009896 78 0.027
Human
learning or memory GO:0007611 90 0.027
negative regulation of calcium ion transport into cytosol GO:0010523 4 0.027
regulation of nucleotide catabolic process GO:0030811 65 0.027
Human
programmed cell death GO:0012501 392 0.026
Human Mouse
regulation of blood vessel size GO:0050880 89 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.026
Human
positive regulation of developmental process GO:0051094 283 0.026
growth GO:0040007 165 0.026
positive regulation of molecular function GO:0044093 230 0.026
Human Mouse
protein complex assembly GO:0006461 263 0.026
female gonad development GO:0008585 53 0.025
negative regulation of metabolic process GO:0009892 331 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
regulation of catalytic activity GO:0050790 304 0.025
Human
regulation of ras protein signal transduction GO:0046578 45 0.025
nucleoside triphosphate metabolic process GO:0009141 144 0.025
Human
immune system process GO:0002376 204 0.025
exocytosis GO:0006887 60 0.025
second messenger mediated signaling GO:0019932 51 0.025
Human Mouse
regulation of intracellular signal transduction GO:1902531 218 0.025
regulation of cellular component movement GO:0051270 150 0.025
Mouse
regulation of secretion by cell GO:1903530 208 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.024
peptidyl amino acid modification GO:0018193 126 0.024
regulation of protein metabolic process GO:0051246 289 0.024
brain development GO:0007420 247 0.024
response to oxygen levels GO:0070482 265 0.024
Mouse
nucleoside metabolic process GO:0009116 179 0.024
Human
negative regulation of response to stimulus GO:0048585 155 0.024
regulation of protein modification process GO:0031399 194 0.024
positive regulation of action potential GO:0045760 8 0.024
positive regulation of cellular catabolic process GO:0031331 71 0.024
Human
regulation of muscle system process GO:0090257 79 0.024
Human Mouse
single organism biosynthetic process GO:0044711 342 0.024
response to growth factor GO:0070848 189 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
response to monosaccharide GO:0034284 159 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
adult locomotory behavior GO:0008344 4 0.023
insulin receptor signaling pathway GO:0008286 24 0.023
macromolecule localization GO:0033036 252 0.023
Human
negative regulation of phosphate metabolic process GO:0045936 80 0.023
purine nucleoside catabolic process GO:0006152 124 0.023
Human
oxidation reduction process GO:0055114 304 0.023
cell type specific apoptotic process GO:0097285 134 0.023
Human Mouse
multicellular organismal homeostasis GO:0048871 49 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
Mouse
regulation of synaptic transmission gabaergic GO:0032228 17 0.023
forebrain development GO:0030900 98 0.023
nucleotide catabolic process GO:0009166 139 0.023
Human
cyclic nucleotide metabolic process GO:0009187 80 0.023
negative regulation of transport GO:0051051 136 0.023
cell differentiation in hindbrain GO:0021533 2 0.022
peptide secretion GO:0002790 86 0.022
regulation of neurological system process GO:0031644 43 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.022
reproduction GO:0000003 245 0.022
actin filament based process GO:0030029 86 0.022
nucleic acid templated transcription GO:0097659 379 0.022
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.022
regulation of actin filament based movement GO:1903115 12 0.022
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
response to peptide hormone GO:0043434 278 0.021
calcium ion homeostasis GO:0055074 162 0.021
cellular response to external stimulus GO:0071496 118 0.021
positive regulation of gene expression GO:0010628 244 0.021
regulation of ion transmembrane transporter activity GO:0032412 48 0.021
Human Mouse
regulation of neuron apoptotic process GO:0043523 83 0.021
nitrogen compound transport GO:0071705 229 0.021
cellular catabolic process GO:0044248 295 0.021
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.021
positive regulation of lipid catabolic process GO:0050996 4 0.021
regulation of action potential GO:0098900 14 0.021
glucose homeostasis GO:0042593 75 0.020
hair cell differentiation GO:0035315 2 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
mitotic cell cycle GO:0000278 49 0.020
rna biosynthetic process GO:0032774 380 0.020
Mouse
regulation of transporter activity GO:0032409 50 0.020
Human Mouse
membrane depolarization GO:0051899 32 0.020
protein tetramerization GO:0051262 38 0.020
cellular protein localization GO:0034613 122 0.020
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
Human
negative regulation of synaptic transmission dopaminergic GO:0032227 4 0.020
dendritic spine organization GO:0097061 12 0.020
male gonad development GO:0008584 59 0.020
positive regulation of synaptic transmission GO:0050806 62 0.020
response to electrical stimulus GO:0051602 56 0.020
regulation of gtp catabolic process GO:0033124 58 0.020
regulation of ion homeostasis GO:2000021 63 0.020
Human Mouse Rat
neuron apoptotic process GO:0051402 88 0.020
carbohydrate homeostasis GO:0033500 75 0.020
gamete generation GO:0007276 124 0.019
regulation of blood circulation GO:1903522 110 0.019
Human Mouse
gtp catabolic process GO:0006184 71 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
Human
central nervous system neuron axonogenesis GO:0021955 1 0.019
reproductive structure development GO:0048608 128 0.019
neuron projection morphogenesis GO:0048812 122 0.019
ephrin receptor signaling pathway GO:0048013 3 0.019
neurotransmitter secretion GO:0007269 33 0.019
single organism membrane organization GO:0044802 74 0.019
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.019
Mouse
intracellular transport GO:0046907 185 0.019
ovulation cycle process GO:0022602 50 0.019
divalent metal ion transport GO:0070838 132 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
regulation of blood pressure GO:0008217 83 0.019
positive regulation of mapk cascade GO:0043410 92 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
Human
neuromuscular process GO:0050905 2 0.018
regulation of cardiac muscle contraction GO:0055117 17 0.018
Human Mouse
activation of mapkkk activity GO:0000185 1 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
Human
regulation of vascular smooth muscle contraction GO:0003056 3 0.018
regulation of ion transport GO:0043269 245 0.018
Human Mouse
nucleoside phosphate catabolic process GO:1901292 140 0.018
Human
response to nutrient GO:0007584 248 0.018
sodium ion transmembrane transport GO:0035725 67 0.018
chemosensory behavior GO:0007635 2 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
secretion by tissue GO:0032941 37 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.018
synapse assembly GO:0007416 29 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
olfactory bulb interneuron differentiation GO:0021889 1 0.017
embryo development GO:0009790 49 0.017
Mouse
neuron development GO:0048666 286 0.017
regulation of peptide transport GO:0090087 87 0.017
cerebellar purkinje cell layer development GO:0021680 2 0.017
response to estradiol GO:0032355 164 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
Human
peptidyl tyrosine modification GO:0018212 72 0.017
regulation of dendrite development GO:0050773 59 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
cellular response to cgmp GO:0071321 2 0.016
limbic system development GO:0021761 38 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
choline transport GO:0015871 4 0.016
peristalsis GO:0030432 2 0.016
specification of organ identity GO:0010092 2 0.016
sexual reproduction GO:0019953 148 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
regulation of neuron death GO:1901214 115 0.016
organic anion transport GO:0015711 132 0.016
neuron death GO:0070997 127 0.016
regulation of organelle organization GO:0033043 80 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
Human
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.015
organophosphate catabolic process GO:0046434 148 0.015
Human
heart morphogenesis GO:0003007 3 0.015
Mouse
cerebellar cortex formation GO:0021697 2 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.015
protein heterooligomerization GO:0051291 89 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
Human
dendritic spine development GO:0060996 20 0.015
negative regulation of release of sequestered calcium ion into cytosol GO:0051280 4 0.015
detection of external stimulus GO:0009581 13 0.015
phasic smooth muscle contraction GO:0014821 3 0.015
negative regulation of protein phosphorylation GO:0001933 44 0.015
insulin secretion GO:0030073 69 0.015
protein transport GO:0015031 132 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
negative regulation of synaptic transmission GO:0050805 29 0.015
regulation of synapse structure and activity GO:0050803 21 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
cell communication involved in cardiac conduction GO:0086065 2 0.015
Mouse
negative regulation of molecular function GO:0044092 133 0.015
peptidyl serine phosphorylation GO:0018105 33 0.015
ventricular cardiac muscle cell action potential GO:0086005 2 0.015
Mouse
auditory receptor cell differentiation GO:0042491 2 0.014
potassium ion transmembrane transport GO:0071805 71 0.014
response to hexose GO:0009746 144 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
guanosine containing compound catabolic process GO:1901069 71 0.014
cellular potassium ion transport GO:0071804 72 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
regulation of tube size GO:0035150 89 0.014
lipid metabolic process GO:0006629 283 0.014
male gamete generation GO:0048232 99 0.014
mesoderm formation GO:0001707 1 0.014
positive regulation of transport GO:0051050 245 0.014
Human Mouse
neuromuscular synaptic transmission GO:0007274 2 0.014
inner ear receptor cell differentiation GO:0060113 2 0.014
protein localization GO:0008104 191 0.014
Human
cognition GO:0050890 92 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
positive regulation of myoblast proliferation GO:2000288 1 0.014
multicellular organism reproduction GO:0032504 233 0.013
peptide transport GO:0015833 97 0.013
micturition GO:0060073 4 0.013
regulation of kinase activity GO:0043549 117 0.013
nucleoside catabolic process GO:0009164 126 0.013
Human
localization of cell GO:0051674 202 0.013
axis specification GO:0009798 4 0.013
positive regulation of intracellular protein transport GO:0090316 20 0.013
body fluid secretion GO:0007589 41 0.013
actin filament organization GO:0007015 42 0.013
response to cytokine GO:0034097 215 0.013
anion transmembrane transport GO:0098656 77 0.013
regulation of cell differentiation GO:0045595 320 0.013
organ formation GO:0048645 3 0.013
response to cgmp GO:0070305 3 0.013
regulation of cell growth GO:0001558 85 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
organelle organization GO:0006996 266 0.013
cell motility GO:0048870 202 0.013
regulation of heart rate GO:0002027 16 0.013
Human Mouse
positive regulation of neuron differentiation GO:0045666 126 0.012
mesoderm development GO:0007498 2 0.012
protein homooligomerization GO:0051260 91 0.012
vascular process in circulatory system GO:0003018 96 0.012
membrane organization GO:0061024 94 0.012
heterocycle catabolic process GO:0046700 167 0.012
Human
potassium ion homeostasis GO:0055075 2 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
carbohydrate metabolic process GO:0005975 130 0.012
mesoderm morphogenesis GO:0048332 1 0.012
locomotion GO:0040011 237 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
Human Mouse Rat
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.012
cytoskeleton organization GO:0007010 111 0.012
regulation of amino acid transport GO:0051955 25 0.012
morphogenesis of embryonic epithelium GO:0016331 3 0.012
positive regulation of cytoskeleton organization GO:0051495 26 0.012
maintenance of location GO:0051235 17 0.012
Human Mouse Rat
regulation of ras gtpase activity GO:0032318 32 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
Human
locomotory exploration behavior GO:0035641 1 0.012
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.012
Human Mouse
protein localization to membrane GO:0072657 36 0.011
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 2 0.011
regulation of striated muscle contraction GO:0006942 21 0.011
Human Mouse
ensheathment of neurons GO:0007272 40 0.011
regulation of actin cytoskeleton organization GO:0032956 30 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
response to acid chemical GO:0001101 222 0.011
negative regulation of neuron death GO:1901215 69 0.011
regulation of respiratory system process GO:0044065 1 0.011
response to carbohydrate GO:0009743 183 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
Human
circulatory system process GO:0003013 183 0.011
Human Mouse
positive regulation of protein metabolic process GO:0051247 178 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
calcium ion transport GO:0006816 131 0.011

Ryr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
heart conduction disease DOID:10273 0 0.022
disease of anatomical entity DOID:7 0 0.022
Human
cardiovascular system disease DOID:1287 0 0.022
Human
long qt syndrome DOID:2843 0 0.020
disease of cellular proliferation DOID:14566 0 0.016
nervous system disease DOID:863 0 0.016
epilepsy syndrome DOID:1826 0 0.015
central nervous system disease DOID:331 0 0.015
brain disease DOID:936 0 0.015
cancer DOID:162 0 0.014