Rattus norvegicus

0 known processes

Sulf2

sulfatase 2

Sulf2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.104
oxoacid metabolic process GO:0043436 290 0.091
Human Rat
positive regulation of multicellular organismal process GO:0051240 387 0.084
organic acid metabolic process GO:0006082 292 0.080
Human Rat
cell motility GO:0048870 202 0.066
regulation of signal transduction GO:0009966 318 0.061
Human
cellular lipid metabolic process GO:0044255 208 0.060
regulation of molecular function GO:0065009 398 0.059
cellular component biogenesis GO:0044085 368 0.048
cell morphogenesis GO:0000902 142 0.046
regulation of multicellular organismal development GO:2000026 376 0.046
cellular component assembly GO:0022607 360 0.046
regulation of secretion GO:0051046 224 0.046
lipid metabolic process GO:0006629 283 0.046
positive regulation of signaling GO:0023056 270 0.046
Human
positive regulation of response to stimulus GO:0048584 285 0.045
Human
intracellular signal transduction GO:0035556 314 0.045
positive regulation of cell communication GO:0010647 271 0.044
Human
response to inorganic substance GO:0010035 377 0.044
organic substance catabolic process GO:1901575 316 0.044
Rat
positive regulation of transport GO:0051050 245 0.043
cellular amino acid metabolic process GO:0006520 107 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
regulation of cell differentiation GO:0045595 320 0.042
cellular component morphogenesis GO:0032989 155 0.042
apoptotic process GO:0006915 381 0.041
protein phosphorylation GO:0006468 345 0.041
positive regulation of developmental process GO:0051094 283 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.040
regulation of intracellular signal transduction GO:1902531 218 0.040
cell cell signaling GO:0007267 335 0.039
amine metabolic process GO:0009308 38 0.039
regulation of phosphate metabolic process GO:0019220 349 0.037
regulation of catalytic activity GO:0050790 304 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
macromolecular complex assembly GO:0065003 273 0.036
response to peptide hormone GO:0043434 278 0.035
programmed cell death GO:0012501 392 0.035
regulation of apoptotic process GO:0042981 335 0.035
positive regulation of neurogenesis GO:0050769 165 0.035
cell projection organization GO:0030030 302 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
regulation of cell development GO:0060284 263 0.034
regulation of programmed cell death GO:0043067 341 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
regulation of protein metabolic process GO:0051246 289 0.033
regulation of protein phosphorylation GO:0001932 183 0.033
regulation of neurogenesis GO:0050767 247 0.033
cell morphogenesis involved in differentiation GO:0000904 119 0.033
cellular catabolic process GO:0044248 295 0.033
Rat
macromolecular complex subunit organization GO:0043933 339 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.032
cellular response to stress GO:0033554 269 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
regulation of hormone levels GO:0010817 187 0.031
single organism intracellular transport GO:1902582 166 0.031
intracellular transport GO:0046907 185 0.031
catabolic process GO:0009056 351 0.031
Rat
nucleic acid templated transcription GO:0097659 379 0.030
cellular component movement GO:0006928 248 0.030
protein oligomerization GO:0051259 191 0.030
response to nutrient levels GO:0031667 370 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
cellular amine metabolic process GO:0044106 38 0.030
protein complex subunit organization GO:0071822 302 0.030
protein complex biogenesis GO:0070271 263 0.029
positive regulation of molecular function GO:0044093 230 0.029
negative regulation of response to stimulus GO:0048585 155 0.029
positive regulation of cell development GO:0010720 176 0.029
cellular ketone metabolic process GO:0042180 51 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
response to acid chemical GO:0001101 222 0.029
regulation of neuron projection development GO:0010975 161 0.029
response to metal ion GO:0010038 253 0.029
reproductive process GO:0022414 372 0.029
organophosphate metabolic process GO:0019637 370 0.029
negative regulation of cell death GO:0060548 229 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
localization of cell GO:0051674 202 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
regulation of nervous system development GO:0051960 264 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
tissue development GO:0009888 252 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
regulation of cellular localization GO:0060341 263 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
response to oxidative stress GO:0006979 186 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
secretion by cell GO:0032940 248 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
regulation of cell projection organization GO:0031344 175 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
Human Rat
regulation of protein modification process GO:0031399 194 0.026
organonitrogen compound catabolic process GO:1901565 179 0.025
Rat
negative regulation of cell communication GO:0010648 158 0.025
neuron projection development GO:0031175 273 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
gland development GO:0048732 155 0.025
single organism catabolic process GO:0044712 283 0.025
Rat
rna metabolic process GO:0016070 406 0.025
protein complex assembly GO:0006461 263 0.025
regulation of cellular component organization GO:0051128 368 0.024
central nervous system development GO:0007417 311 0.024
response to peptide GO:1901652 292 0.024
negative regulation of metabolic process GO:0009892 331 0.024
positive regulation of cell death GO:0010942 184 0.024
regulation of neuron differentiation GO:0045664 208 0.024
behavior GO:0007610 205 0.024
purine containing compound metabolic process GO:0072521 253 0.024
homeostatic process GO:0042592 331 0.024
regulation of secretion by cell GO:1903530 208 0.024
positive regulation of apoptotic process GO:0043065 154 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
single organism biosynthetic process GO:0044711 342 0.023
multi organism reproductive process GO:0044703 262 0.023
neuron development GO:0048666 286 0.023
macromolecule localization GO:0033036 252 0.023
fatty acid metabolic process GO:0006631 99 0.022
cation homeostasis GO:0055080 195 0.022
biological adhesion GO:0022610 110 0.022
cation transport GO:0006812 382 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
secretion GO:0046903 307 0.022
regulation of phosphorylation GO:0042325 248 0.022
neuron projection morphogenesis GO:0048812 122 0.022
response to extracellular stimulus GO:0009991 380 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
regulation of transcription dna templated GO:0006355 374 0.022
positive regulation of nervous system development GO:0051962 178 0.022
chemical homeostasis GO:0048878 292 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
chemotaxis GO:0006935 66 0.021
defense response GO:0006952 194 0.021
protein transport GO:0015031 132 0.021
response to biotic stimulus GO:0009607 226 0.020
cardiac chamber development GO:0003205 1 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
negative regulation of signaling GO:0023057 157 0.020
heart morphogenesis GO:0003007 3 0.020
locomotion GO:0040011 237 0.020
response to toxic substance GO:0009636 133 0.020
regulation of system process GO:0044057 208 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
cellular protein localization GO:0034613 122 0.020
organelle organization GO:0006996 266 0.020
metal ion transport GO:0030001 289 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
cellular ion homeostasis GO:0006873 184 0.020
calcium ion homeostasis GO:0055074 162 0.020
negative regulation of cell differentiation GO:0045596 99 0.019
response to oxygen levels GO:0070482 265 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
transcription dna templated GO:0006351 377 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
positive regulation of gene expression GO:0010628 244 0.019
regeneration GO:0031099 163 0.019
single organism reproductive process GO:0044702 297 0.019
response to glucocorticoid GO:0051384 223 0.019
protein localization GO:0008104 191 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
rna biosynthetic process GO:0032774 380 0.019
axon development GO:0061564 96 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.018
Rat
negative regulation of apoptotic process GO:0043066 181 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
ion homeostasis GO:0050801 212 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
motor neuron axon guidance GO:0008045 1 0.018
response to ethanol GO:0045471 162 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
positive regulation of protein modification process GO:0031401 142 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
ras protein signal transduction GO:0007265 29 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cell adhesion GO:0007155 110 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
positive regulation of signal transduction GO:0009967 175 0.017
Human
positive regulation of protein phosphorylation GO:0001934 135 0.017
response to insulin GO:0032868 133 0.017
regulation of catabolic process GO:0009894 113 0.017
cell activation GO:0001775 97 0.017
cell migration GO:0016477 197 0.017
heterocycle catabolic process GO:0046700 167 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
growth GO:0040007 165 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
transmembrane transport GO:0055085 412 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
head development GO:0060322 247 0.017
regulation of response to stress GO:0080134 126 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
axonogenesis GO:0007409 71 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
regulation of rna metabolic process GO:0051252 391 0.016
oxidation reduction process GO:0055114 304 0.016
metanephric comma shaped body morphogenesis GO:0072278 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
regulation of membrane potential GO:0042391 110 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
cellular cation homeostasis GO:0030003 180 0.016
response to hypoxia GO:0001666 231 0.016
cardiovascular system development GO:0072358 134 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of cell proliferation GO:0042127 359 0.016
signal release GO:0023061 145 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
regulation of anatomical structure size GO:0090066 135 0.016
regulation of protein transport GO:0051223 68 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
metal ion homeostasis GO:0055065 186 0.015
cellular homeostasis GO:0019725 252 0.015
salivary gland development GO:0007431 3 0.015
reproduction GO:0000003 245 0.015
neuron differentiation GO:0030182 368 0.015
response to external biotic stimulus GO:0043207 221 0.015
regulation of growth GO:0040008 105 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of kinase activity GO:0043549 117 0.015
mapk cascade GO:0000165 140 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
regulation of mapk cascade GO:0043408 116 0.015
steroid metabolic process GO:0008202 73 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
regulation of cell growth GO:0001558 85 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
organ regeneration GO:0031100 101 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
small molecule biosynthetic process GO:0044283 124 0.015
taxis GO:0042330 67 0.014
cell part morphogenesis GO:0032990 123 0.014
response to corticosteroid GO:0031960 235 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
learning or memory GO:0007611 90 0.014
actin filament based process GO:0030029 86 0.014
reproductive system development GO:0061458 128 0.014
negative regulation of developmental process GO:0051093 125 0.014
salivary gland morphogenesis GO:0007435 1 0.014
bmp signaling pathway GO:0030509 4 0.014
single organism organelle organization GO:1902589 180 0.014
cellular macromolecule localization GO:0070727 122 0.014
response to bacterium GO:0009617 200 0.014
cellular chemical homeostasis GO:0055082 247 0.014
nucleotide metabolic process GO:0009117 279 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of locomotion GO:0040012 148 0.014
regulation of transferase activity GO:0051338 123 0.014
blood circulation GO:0008015 183 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
dephosphorylation GO:0016311 98 0.014
axis specification GO:0009798 4 0.014
synaptic transmission GO:0007268 235 0.014
nucleoside metabolic process GO:0009116 179 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
hepaticobiliary system development GO:0061008 90 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of body fluid levels GO:0050878 90 0.013
response to estradiol GO:0032355 164 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
response to growth factor GO:0070848 189 0.013
aromatic compound catabolic process GO:0019439 168 0.013
circulatory system process GO:0003013 183 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of peptide transport GO:0090087 87 0.013
regulation of hormone secretion GO:0046883 106 0.013
response to reactive oxygen species GO:0000302 120 0.013
response to estrogen GO:0043627 232 0.013
cell projection morphogenesis GO:0048858 123 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
organophosphate catabolic process GO:0046434 148 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
multicellular organism reproduction GO:0032504 233 0.013
chromosome segregation GO:0007059 2 0.013
negative regulation of transport GO:0051051 136 0.013
calcium ion transport GO:0006816 131 0.013
regulation of ion transport GO:0043269 245 0.012
anterior posterior pattern specification GO:0009952 1 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
nitrogen compound transport GO:0071705 229 0.012
cellular response to lipid GO:0071396 201 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
anion transport GO:0006820 178 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
nucleotide catabolic process GO:0009166 139 0.012
aging GO:0007568 241 0.012
response to wounding GO:0009611 254 0.012
response to ketone GO:1901654 182 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
gamete generation GO:0007276 124 0.012
response to cytokine GO:0034097 215 0.012
ion transmembrane transport GO:0034220 365 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
hormone secretion GO:0046879 115 0.012
brain development GO:0007420 247 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
peptide transport GO:0015833 97 0.012
cytoplasmic transport GO:0016482 115 0.012
regulation of dendrite development GO:0050773 59 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
proteolysis GO:0006508 175 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
response to carbohydrate GO:0009743 183 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
adult locomotory behavior GO:0008344 4 0.012
amide transport GO:0042886 105 0.012
regulation of cellular component movement GO:0051270 150 0.011
response to camp GO:0051591 91 0.011
regulation of protein kinase activity GO:0045859 105 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
positive regulation of catabolic process GO:0009896 78 0.011
response to amino acid GO:0043200 75 0.011
inflammatory response GO:0006954 150 0.011
tube development GO:0035295 89 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
response to organophosphorus GO:0046683 102 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
leukocyte activation GO:0045321 76 0.011
dendrite development GO:0016358 72 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
respiratory system development GO:0060541 45 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
organic anion transport GO:0015711 132 0.011
rhythmic process GO:0048511 156 0.011
regulation of cell motility GO:2000145 131 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
response to glucose GO:0009749 136 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
development of primary sexual characteristics GO:0045137 107 0.011
circulatory system development GO:0072359 134 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
lipid biosynthetic process GO:0008610 128 0.011
synapse organization GO:0050808 46 0.011
positive regulation of cell migration GO:0030335 96 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
wound healing GO:0042060 122 0.011
response to other organism GO:0051707 220 0.011
gastrulation GO:0007369 2 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
single organism behavior GO:0044708 130 0.011
regulation of behavior GO:0050795 61 0.011
developmental process involved in reproduction GO:0003006 159 0.011
gliogenesis GO:0042063 93 0.011
ossification GO:0001503 70 0.011
peptidyl amino acid modification GO:0018193 126 0.011
liver development GO:0001889 90 0.011
peptide hormone secretion GO:0030072 84 0.011
peptide secretion GO:0002790 86 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
establishment of tissue polarity GO:0007164 2 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
single organism cellular localization GO:1902580 102 0.011
negative regulation of secretion GO:0051048 82 0.010
rho protein signal transduction GO:0007266 11 0.010
cellular hormone metabolic process GO:0034754 49 0.010
negative regulation of gene expression GO:0010629 199 0.010
metanephric s shaped body morphogenesis GO:0072284 2 0.010
hormone transport GO:0009914 121 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
heart development GO:0007507 72 0.010
mesoderm development GO:0007498 2 0.010
divalent inorganic cation transport GO:0072511 134 0.010
regulation of protein localization GO:0032880 81 0.010
embryonic pattern specification GO:0009880 1 0.010
spindle organization GO:0007051 2 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
hormone metabolic process GO:0042445 69 0.010
dna metabolic process GO:0006259 96 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
sex differentiation GO:0007548 113 0.010
positive regulation of secretion GO:0051047 140 0.010

Sulf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
disease of cellular proliferation DOID:14566 0 0.016
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.013
organ system cancer DOID:0050686 0 0.012
cancer DOID:162 0 0.012
musculoskeletal system disease DOID:17 0 0.012
inherited metabolic disorder DOID:655 0 0.011
sensory system disease DOID:0050155 0 0.011