Rattus norvegicus

11 known processes

Mepe

matrix extracellular phosphoglycoprotein

Mepe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 202 0.270
positive regulation of response to stimulus GO:0048584 285 0.240
regulation of apoptotic process GO:0042981 335 0.190
programmed cell death GO:0012501 392 0.135
response to cytokine GO:0034097 215 0.133
cell migration GO:0016477 197 0.115
positive regulation of cell communication GO:0010647 271 0.109
lipid metabolic process GO:0006629 283 0.102
circulatory system process GO:0003013 183 0.099
regulation of programmed cell death GO:0043067 341 0.096
chemical homeostasis GO:0048878 292 0.096
neuron differentiation GO:0030182 368 0.091
regulation of cell differentiation GO:0045595 320 0.085
nucleic acid templated transcription GO:0097659 379 0.085
regulation of cellular component movement GO:0051270 150 0.085
localization of cell GO:0051674 202 0.084
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.083
rna metabolic process GO:0016070 406 0.082
positive regulation of phosphate metabolic process GO:0045937 262 0.081
cellular component movement GO:0006928 248 0.081
intracellular signal transduction GO:0035556 314 0.081
positive regulation of neurogenesis GO:0050769 165 0.078
positive regulation of cell motility GO:2000147 97 0.075
response to oxygen levels GO:0070482 265 0.073
regulation of rna metabolic process GO:0051252 391 0.073
regulation of rna biosynthetic process GO:2001141 381 0.072
regulation of transcription dna templated GO:0006355 374 0.071
positive regulation of programmed cell death GO:0043068 157 0.070
response to nutrient levels GO:0031667 370 0.068
positive regulation of transcription dna templated GO:0045893 197 0.067
cellular response to oxygen containing compound GO:1901701 386 0.066
positive regulation of cell death GO:0010942 184 0.063
cellular divalent inorganic cation homeostasis GO:0072503 162 0.059
positive regulation of cell differentiation GO:0045597 217 0.058
negative regulation of apoptotic process GO:0043066 181 0.058
regulation of protein metabolic process GO:0051246 289 0.057
apoptotic process GO:0006915 381 0.057
regulation of phosphate metabolic process GO:0019220 349 0.057
potassium ion transport GO:0006813 97 0.056
locomotion GO:0040011 237 0.056
regulation of multicellular organismal development GO:2000026 376 0.055
tissue remodeling GO:0048771 40 0.055
blood circulation GO:0008015 183 0.055
synaptic transmission GO:0007268 235 0.054
positive regulation of rna biosynthetic process GO:1902680 197 0.053
response to estrogen GO:0043627 232 0.053
regulation of response to stress GO:0080134 126 0.053
response to external biotic stimulus GO:0043207 221 0.053
cellular chemical homeostasis GO:0055082 247 0.053
positive regulation of signaling GO:0023056 270 0.052
regulation of hormone levels GO:0010817 187 0.052
reproductive process GO:0022414 372 0.052
regulation of intracellular signal transduction GO:1902531 218 0.051
positive regulation of gene expression GO:0010628 244 0.051
regulation of signal transduction GO:0009966 318 0.051
negative regulation of programmed cell death GO:0043069 183 0.050
positive regulation of cell proliferation GO:0008284 249 0.050
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.049
response to inorganic substance GO:0010035 377 0.049
positive regulation of signal transduction GO:0009967 175 0.049
transcription from rna polymerase ii promoter GO:0006366 252 0.049
regulation of protein modification process GO:0031399 194 0.049
regulation of immune system process GO:0002682 123 0.048
regulation of neurogenesis GO:0050767 247 0.048
positive regulation of apoptotic process GO:0043065 154 0.048
response to decreased oxygen levels GO:0036293 237 0.047
proteolysis GO:0006508 175 0.047
ion homeostasis GO:0050801 212 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.045
positive regulation of nucleic acid templated transcription GO:1903508 197 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
positive regulation of nervous system development GO:0051962 178 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.043
positive regulation of cell development GO:0010720 176 0.043
positive regulation of rna metabolic process GO:0051254 203 0.043
positive regulation of developmental process GO:0051094 283 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
positive regulation of multicellular organismal process GO:0051240 387 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
response to radiation GO:0009314 137 0.042
central nervous system development GO:0007417 311 0.042
regulation of cell proliferation GO:0042127 359 0.042
positive regulation of molecular function GO:0044093 230 0.042
response to bacterium GO:0009617 200 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
response to lipopolysaccharide GO:0032496 191 0.040
positive regulation of catalytic activity GO:0043085 184 0.040
cell projection organization GO:0030030 302 0.039
positive regulation of protein metabolic process GO:0051247 178 0.038
positive regulation of phosphorylation GO:0042327 177 0.038
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.038
cellular homeostasis GO:0019725 252 0.038
response to biotic stimulus GO:0009607 226 0.037
regulation of blood circulation GO:1903522 110 0.037
inflammatory response GO:0006954 150 0.037
response to other organism GO:0051707 220 0.037
negative regulation of cell death GO:0060548 229 0.037
regulation of membrane potential GO:0042391 110 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
neuron projection morphogenesis GO:0048812 122 0.036
olfactory learning GO:0008355 1 0.036
regulation of transferase activity GO:0051338 123 0.036
ras protein signal transduction GO:0007265 29 0.036
response to molecule of bacterial origin GO:0002237 194 0.036
regulation of cell development GO:0060284 263 0.035
rhythmic process GO:0048511 156 0.035
cellular response to cytokine stimulus GO:0071345 127 0.035
cell part morphogenesis GO:0032990 123 0.034
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
smooth muscle cell proliferation GO:0048659 77 0.034
regulation of protein phosphorylation GO:0001932 183 0.034
immune response GO:0006955 104 0.034
response to toxic substance GO:0009636 133 0.033
cytosolic calcium ion homeostasis GO:0051480 140 0.033
regulation of phosphorylation GO:0042325 248 0.033
transcription dna templated GO:0006351 377 0.033
regulation of catalytic activity GO:0050790 304 0.033
homeostatic process GO:0042592 331 0.033
single organism behavior GO:0044708 130 0.033
positive regulation of protein phosphorylation GO:0001934 135 0.032
wound healing GO:0042060 122 0.032
regulation of mapk cascade GO:0043408 116 0.032
neuron projection development GO:0031175 273 0.032
single organism catabolic process GO:0044712 283 0.032
negative regulation of rna metabolic process GO:0051253 123 0.032
calcium ion homeostasis GO:0055074 162 0.031
gliogenesis GO:0042063 93 0.031
behavior GO:0007610 205 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.031
cellular ion homeostasis GO:0006873 184 0.030
divalent inorganic cation homeostasis GO:0072507 165 0.030
positive regulation of cellular component movement GO:0051272 102 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
protein phosphorylation GO:0006468 345 0.029
regulation of synaptic transmission GO:0050804 141 0.029
epithelial cell proliferation GO:0050673 54 0.029
cellular component assembly GO:0022607 360 0.029
single organism reproductive process GO:0044702 297 0.029
lipid biosynthetic process GO:0008610 128 0.029
immune system process GO:0002376 204 0.029
cellular cation homeostasis GO:0030003 180 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
cellular calcium ion homeostasis GO:0006874 160 0.028
regulation of immune response to tumor cell GO:0002837 3 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.027
single organism biosynthetic process GO:0044711 342 0.027
response to extracellular stimulus GO:0009991 380 0.027
head development GO:0060322 247 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
positive regulation of neuron differentiation GO:0045666 126 0.026
response to mechanical stimulus GO:0009612 134 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of cell migration GO:0030334 128 0.026
mapk cascade GO:0000165 140 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
negative regulation of metabolic process GO:0009892 331 0.025
protein complex subunit organization GO:0071822 302 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
reproductive system development GO:0061458 128 0.025
regulation of ion transport GO:0043269 245 0.024
cellular response to biotic stimulus GO:0071216 59 0.024
muscle cell proliferation GO:0033002 84 0.024
regulation of molecular function GO:0065009 398 0.024
response to corticosteroid GO:0031960 235 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
response to peptide GO:1901652 292 0.024
biological adhesion GO:0022610 110 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
response to tumor necrosis factor GO:0034612 56 0.023
limb morphogenesis GO:0035108 4 0.023
reproduction GO:0000003 245 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
brain development GO:0007420 247 0.023
regulation of nervous system development GO:0051960 264 0.023
organ formation GO:0048645 3 0.023
neuron development GO:0048666 286 0.023
cellular component biogenesis GO:0044085 368 0.023
epithelium development GO:0060429 96 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
positive regulation of protein kinase activity GO:0045860 73 0.021
cellular response to molecule of bacterial origin GO:0071219 56 0.021
multicellular organism reproduction GO:0032504 233 0.021
ossification GO:0001503 70 0.021
negative regulation of transport GO:0051051 136 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
immunoglobulin mediated immune response GO:0016064 4 0.021
organic hydroxy compound metabolic process GO:1901615 115 0.021
regulation of cell growth GO:0001558 85 0.020
positive regulation of cell migration GO:0030335 96 0.020
response to ketone GO:1901654 182 0.020
organic acid metabolic process GO:0006082 292 0.020
regulation of cell motility GO:2000145 131 0.020
regulation of neuron differentiation GO:0045664 208 0.020
signal release GO:0023061 145 0.020
response to reactive oxygen species GO:0000302 120 0.020
response to wounding GO:0009611 254 0.020
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
positive regulation of immune system process GO:0002684 90 0.020
negative regulation of gene expression GO:0010629 199 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
male gonad development GO:0008584 59 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
regulation of kinase activity GO:0043549 117 0.020
negative regulation of ion transport GO:0043271 51 0.020
response to growth factor GO:0070848 189 0.020
positive regulation of kinase activity GO:0033674 77 0.020
regulation of lipid metabolic process GO:0019216 68 0.020
appendage morphogenesis GO:0035107 4 0.020
tissue development GO:0009888 252 0.019
positive regulation of epithelial cell proliferation GO:0050679 32 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
cation homeostasis GO:0055080 195 0.019
jak stat cascade GO:0007259 26 0.019
steroid metabolic process GO:0008202 73 0.019
chemosensory behavior GO:0007635 2 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
erk1 and erk2 cascade GO:0070371 48 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
salivary gland development GO:0007431 3 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
cellular lipid catabolic process GO:0044242 37 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
positive regulation of protein modification process GO:0031401 142 0.018
steroid biosynthetic process GO:0006694 48 0.018
regulation of anatomical structure size GO:0090066 135 0.018
negative regulation of signaling GO:0023057 157 0.018
forebrain development GO:0030900 98 0.018
gonad development GO:0008406 104 0.018
neurological system process GO:0050877 219 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
regulation of small gtpase mediated signal transduction GO:0051056 48 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
response to hypoxia GO:0001666 231 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of epithelial cell proliferation GO:0050678 49 0.017
rna biosynthetic process GO:0032774 380 0.017
regulation of defense response GO:0031347 68 0.017
female pregnancy GO:0007565 122 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
cellular response to tumor necrosis factor GO:0071356 46 0.016
regulation of neuron death GO:1901214 115 0.016
regulation of cell activation GO:0050865 50 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
sex differentiation GO:0007548 113 0.016
response to hydrogen peroxide GO:0042542 89 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
negative regulation of immune system process GO:0002683 39 0.016
urogenital system development GO:0001655 78 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of neuron projection development GO:0010975 161 0.016
cellular catabolic process GO:0044248 295 0.016
activation of protein kinase activity GO:0032147 47 0.016
regulation of vasculature development GO:1901342 44 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.015
response to temperature stimulus GO:0009266 94 0.015
peptidyl amino acid modification GO:0018193 126 0.015
myeloid leukocyte activation GO:0002274 36 0.015
cellular response to lipid GO:0071396 201 0.015
response to acid chemical GO:0001101 222 0.015
olfactory behavior GO:0042048 2 0.015
secretion by cell GO:0032940 248 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular amine metabolic process GO:0044106 38 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
cell morphogenesis GO:0000902 142 0.015
vasculature development GO:0001944 70 0.015
cellular ketone metabolic process GO:0042180 51 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
response to ethanol GO:0045471 162 0.015
catabolic process GO:0009056 351 0.015
response to isoquinoline alkaloid GO:0014072 28 0.015
anatomical structure morphogenesis GO:0009653 298 0.014
axonogenesis GO:0007409 71 0.014
growth GO:0040007 165 0.014
defense response GO:0006952 194 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
response to peptide hormone GO:0043434 278 0.014
response to retinoic acid GO:0032526 63 0.014
regulation of locomotion GO:0040012 148 0.014
response to tumor cell GO:0002347 4 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
ovulation cycle GO:0042698 67 0.014
regulation of cell projection organization GO:0031344 175 0.014
small molecule catabolic process GO:0044282 59 0.014
protein homooligomerization GO:0051260 91 0.014
developmental growth GO:0048589 100 0.014
negative regulation of developmental process GO:0051093 125 0.014
male sex differentiation GO:0046661 64 0.014
gamete generation GO:0007276 124 0.014
positive regulation of transferase activity GO:0051347 81 0.014
response to vitamin GO:0033273 131 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
purine containing compound metabolic process GO:0072521 253 0.013
regulation of system process GO:0044057 208 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
regulation of protein kinase activity GO:0045859 105 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
hormone metabolic process GO:0042445 69 0.013
organophosphate metabolic process GO:0019637 370 0.013
response to estradiol GO:0032355 164 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
response to light stimulus GO:0009416 52 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
multi organism reproductive process GO:0044703 262 0.013
aging GO:0007568 241 0.013
cognition GO:0050890 92 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
oxidation reduction process GO:0055114 304 0.012
cellular response to external stimulus GO:0071496 118 0.012
dendrite development GO:0016358 72 0.012
amine metabolic process GO:0009308 38 0.012
regulation of cellular component size GO:0032535 51 0.012
regulation of inflammatory response GO:0050727 48 0.012
regulation of axonogenesis GO:0050770 37 0.012
activation of immune response GO:0002253 26 0.012
nucleoside metabolic process GO:0009116 179 0.012
small molecule biosynthetic process GO:0044283 124 0.012
protein localization GO:0008104 191 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
cellular response to nutrient levels GO:0031669 60 0.012
regulation of homeostatic process GO:0032844 101 0.012
neuron death GO:0070997 127 0.012
sensory perception of pain GO:0019233 73 0.012
metal ion homeostasis GO:0055065 186 0.012
innate immune response GO:0045087 35 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
immune response to tumor cell GO:0002418 3 0.012
epithelial cell differentiation GO:0030855 71 0.012
protein complex assembly GO:0006461 263 0.012
cellular response to stress GO:0033554 269 0.012
negative regulation of cell communication GO:0010648 158 0.012
response to metal ion GO:0010038 253 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
regulation of cellular component organization GO:0051128 368 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
oxoacid metabolic process GO:0043436 290 0.011
taxis GO:0042330 67 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
regulation of actin filament based process GO:0032970 42 0.011
sodium ion transport GO:0006814 82 0.011
sensory perception GO:0007600 101 0.011
regulation of metal ion transport GO:0010959 118 0.011
renal system development GO:0072001 67 0.011
regulation of blood vessel size GO:0050880 89 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of locomotion GO:0040017 102 0.011
rho protein signal transduction GO:0007266 11 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
detection of visible light GO:0009584 3 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
cellular response to alkaloid GO:0071312 25 0.011
cellular lipid metabolic process GO:0044255 208 0.011
development of primary sexual characteristics GO:0045137 107 0.011
action potential GO:0001508 54 0.011
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.011
cellular response to abiotic stimulus GO:0071214 85 0.010
response to morphine GO:0043278 27 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
protein oligomerization GO:0051259 191 0.010
b cell mediated immunity GO:0019724 4 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
lymphocyte activation involved in immune response GO:0002285 3 0.010
acute inflammatory response GO:0002526 58 0.010
learning or memory GO:0007611 90 0.010
regulation of gtpase activity GO:0043087 57 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
hormone secretion GO:0046879 115 0.010

Mepe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.023
disease of anatomical entity DOID:7 0 0.023
retinal disease DOID:5679 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019